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Journal Articles

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Geethu Emily Thomas, PhDMSc,BSc, Grace Egan, MD, Laura Garcia Prat, Boaz Nachmias, MD PhD, Jordan M Chin, Fieke W Hoff, BSc, Kerstin Kaufmann, PhD, Rose Hurren, BSc, Marcela Gronda, MSc, Neil MacLean, Xiaoming Wang, Veronique Voisin, PhD, Aaron Botham, Andrea Arruda, Mark D. Minden, MD PhD, Gary D Bader, Steven M. Kornblau, MD, John E. Dick, PhD, Aaron D Schimmer, MD PhD

Blood (2019) 134 (Supplement_1): 2532.

https://doi.org/10.1182/blood-2019-123121

Published: 2019

Journal Articles

Human and Pathogen Derived Ndpks Act As Novel Damps and PAMPs to Drive Leukemia Cell Survival and Progression through Signaling Via the TLR4-Mediated Alternative NLRP3 Inflammasome Pathway

Sandro Trova, PhD, Matthew Fenton, MBChB, Bhavini Chauhan, BSc, Avani Puri, Santosh Lomada, BSc, PhD, Alexandra Adams, Thomas Wieland, BSc, PhD, Mark T Drayson, MB ChB, PhD FRCPath, Farhat Latif Khanim, PhD, Chistopher M Bunce, BSc, Fei Lin, MBChB

Blood (2019) 134 (Supplement_1): 2684.

https://doi.org/10.1182/blood-2019-131236

Published: 2019

Journal Articles

Therapeutic Targeting of Telomere Diseases Via Novel Small Molecule Modulators of Non-Coding RNA Biogenesis

Neha Nagpal, PhD, Jianing Wang, Emily Lo, Albert Tai, Patrick Cahan, PhD, Yick Fong, PhD, Suneet Agarwal, MDPhD

Blood (2018) 132 (Supplement 1): 647.

https://doi.org/10.1182/blood-2018-99-118800

Published: 2018

Journal Articles

VDJH Gene Repertoire Analysis in Multiple Myeloma (MM) Patients: Correlation with Clinical Data

Alejandro Medina, Cristina Jiménez, PhD, Maria E Sarasquete, PhD, Noemi Puig, MD PhD, Ana Balanzategui, Miguel Alcoceba, PhD, Veronica Gonzalez De La Calle, MD PhD, Maria Garcia-Alvarez, B.Sc., Isabel Prieto-Conde, PhD, Carmen Chillon, PhD, Enrique M. Ocio, MD, Norma C. Gutierrez, MD PhD, Maria-Victoria Mateos, MD PhD, Joaquin Martínez-López, MD PhD, Juan Jose Lahuerta, MD PhD, Jesús F San-Miguel, MD, Marcos González, MD PhD, Ramon García-Sanz, MD PhD

Blood (2018) 132 (Supplement 1): 4446.

https://doi.org/10.1182/blood-2018-99-114627

Published: 2018

Journal Articles

Determination of the Origin of the t(1;19) TCF3-PBX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Daniel Hein, PhD, Karin Dreisig, PhD, Shai Izraeli, MD, Kjeld Schmiegelow, MD, Arndt Borkhardt, MD, Ute Fischer, PhD

Blood (2018) 132 (Supplement 1): 4093.

https://doi.org/10.1182/blood-2018-99-110521

Published: 2018

Journal Articles

2% of Healthy Newborns Reveal ETV6-RUNX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Daniel Schaefer, MSc, Marianne Olsen, MD, Ulrik Lausten-Thomsen, MD PhD, Cyrill Schipp, MSc, Martin Stanulla, MD, Robert K. Slany, PhD, Kjeld Schmiegelow, MD DMSc, Arndt Borkhardt, MD, Ute Fischer, PhD

Blood (2016) 128 (22): 4082.

https://doi.org/10.1182/blood.V128.22.4082.4082

Published: 2016

Journal Articles

Lmo2's Oncogenic Function in T-Cell Leukemia Requires Ldb1

Liqi Li, PhD, Justin H. Layer, PhD, Claude Warzecha, PhD, Rati Tripathi, PhD, Paul Love, MD PhD, Utpal P. Dave, MD

Blood (2015) 126 (23): 3663.

https://doi.org/10.1182/blood.V126.23.3663.3663

Published: 2015

Journal Articles

Gipfel – a Novel Method for Unbiased Molecular ETV6-RUNX1 Screening of Healthy Newborns

Ute Fischer, PhD, Daniel Schäfer, MSc, Elisa Füller, MSc, Katrine Ask, MSc, Pina Fanny Ida Krell, MSc, Martin Stanulla, MD, Marianne Olsen, MD, Kjeld Schmiegelow, Robert K. Slany, PhD, Arndt Borkhardt, MD

Blood (2014) 124 (21): 5340.

https://doi.org/10.1182/blood.V124.21.5340.5340

Published: 2014

Journal Articles

DNA Demethylation By Activation-Induced Cytidine Deaminase in B Cell Lymphoma

Yang Xi, PhD, Velizar Shivarov, MD, PhD, Gur Yaari, PhD, Steven Kleinstein, PhD, Matthew P. Strout, MD, PhD

Blood (2014) 124 (21): 3549.

https://doi.org/10.1182/blood.V124.21.3549.3549

Published: 2014

Journal Articles

Hematopoietic Stem Cells Are Dependent On Homologous Recombination Only During Active Cell Cycle in Nuclease-Mutant Exonuclease1 mut mice

Amar Desai, Stanton L. Gerson, MD, Yulan Qing, PhD

Blood (2012) 120 (21): 1225.

https://doi.org/10.1182/blood.V120.21.1225.1225

Published: 2012

Journal Articles

The 3'-5' Exonuclease, TREX1, Interacts with Poly(ADP-ribose) Polymerase-1 (PARP1) in Response to DNA Damage

Takuya Miyazaki, MD, PhD, Yong-Soo Kim, PhD, Jeong-Heon Yoon, PhD, Hongsheng Wang, MD, PhD, Herbert C. Morse, III, MD

Blood (2012) 120 (21): 1046.

https://doi.org/10.1182/blood.V120.21.1046.1046

Published: 2012

Journal Articles

Whole Genome Sequencing of Four CD34+-Derived iPSC Polycythemia Vera Clones From a Single Female

Lifeng Tian, PhD., Lucie Piterkova, PhD, Linghua Wang, PhD, Zhaohui Ye, PhD, Linzhao Cheng, PhD, David A. Wheeler, PhD, Hakon Hakonarson, MD, PhD, Josef T Prchal, MD

Blood (2012) 120 (21): 1755.

https://doi.org/10.1182/blood.V120.21.1755.1755

Published: 2012

Journal Articles

Exo1 Independent DNA Mismatch Repair Pathway in Hematopoiesis.

Amar Desai, Yulan Qing, PhD, Min Liu, Jonathan Kenyon, BS, Uchenna Nwafor, Stanton L. Gerson, MD

Blood (2009) 114 (22): 2526.

https://doi.org/10.1182/blood.V114.22.2526.2526

Published: 2009

Journal Articles

High-Resolution Genome Wide Copy Number Alteration (CNA) and Loss of Heterozigosity (LOH) Analysis in Chronic Myeloid Leukemia (CML) Shows That High and Intermediate Sokal Risk Pts (Pts) Have Multiple Losses Targeting Genes Involved in DNA Repair.

Simona Soverini, PhD, Sabrina Colarossi, Alessandra Gnani, Annalisa Astolfi, Serena Formica, Fausto Castagnetti, Francesca Palandri, Gabriele Gugliotta, Angela Poerio, Ilaria Iacobucci, Marilina Amabile, Giulia Marzocchi, Simona Luatti, Carolina Terragna, Sandra Durante, Nicoletta Testoni, Gianantonio Rosti, Michele Baccarani, Giovanni Martinelli

Blood (2009) 114 (22): 3262.

https://doi.org/10.1182/blood.V114.22.3262.3262

Published: 2009

Journal Articles

Establishment of a Highly Sensitive Allele Specific Wild Type Blocker Polymerase Chain Reaction Followed by Pyrosequencing for Detection of the p.D816V Point Mutation.

Udo Siebolts, MD, MSc, Haifa Kathrin Al-Ali, MD, Dietger Niederwieser, MD, Claudia Wickenhauser, MD

Blood (2009) 114 (22): 4975.

https://doi.org/10.1182/blood.V114.22.4975.4975

Published: 2009

Journal Articles

BCR/ABL Stimulates WRN Helicase Activity To Facilitate DNA Double-Strand Breaks Repair.

Artur Slupianek, Stanislaw Jozwiakowski, Dariusz Pytel, Tomasz Poplawski, Michal Nowicki, Tomasz Skorski

Blood (2007) 110 (11): 1024.

https://doi.org/10.1182/blood.V110.11.1024.1024

Published: 2007

Journal Articles

Telomeric Recombination in Lymphocytes Implicates ALT, an Alternative Mechanism for Telomere Length Maintenance, in Normal Human Hematopoietic Cells.

Rodrigo T. Calado, MD, PhD, Solomon A. Graf, BsC, Neal S. Young, MD

Blood (2007) 110 (11): 1332.

https://doi.org/10.1182/blood.V110.11.1332.1332

Published: 2007

Journal Articles

BCR/ABL and Other Oncogenic Fusion Tyrosine Kinases (FTKs) Stimulate Single Strand Annealing (SSA), the Rare and Extremely Unfaithful DNA Double-Strand Break Repair Pathway To Facilitate Genomic Instability in Hematologic Malignancies.

Kimberly Cramer, Emir T. Penserga, Akhil Reddy, Jonathan Wosen, Tomasz Skorski

Blood (2007) 110 (11): 998.

https://doi.org/10.1182/blood.V110.11.998.998

Published: 2007

Journal Articles

Physical and Functional Association of the MRN Complex with Human Telomerase in Multiple Myeloma.

James J. Driscoll, MD, PhD, Robert C. Bertheau, Masood A. Shammas, PhD, Rao H. Prabhala, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2006) 108 (11): 5076.

https://doi.org/10.1182/blood.V108.11.5076.5076

Published: 2006

Journal Articles

BCR/ABL Regulates the Expression and Interacts with Werner Syndrome Helicase/Exonuclease To Modulate Its Biochemical Properties.

Artur Slupianek, PhD, Stanislaw Jozwiakowski, Ewa Gurdek, Michal O. Nowicki, Tomasz Skorski, MD, PhD

Blood (2005) 106 (11): 2873.

https://doi.org/10.1182/blood.V106.11.2873.2873

Published: 2005

NARROW

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Human and Pathogen Derived Ndpks Act As Novel Damps and PAMPs to Drive Leukemia Cell Survival and Progression through Signaling Via the TLR4-Mediated Alternative NLRP3 Inflammasome Pathway

Therapeutic Targeting of Telomere Diseases Via Novel Small Molecule Modulators of Non-Coding RNA Biogenesis

VDJH Gene Repertoire Analysis in Multiple Myeloma (MM) Patients: Correlation with Clinical Data

Determination of the Origin of the t(1;19) TCF3-PBX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

2% of Healthy Newborns Reveal ETV6-RUNX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Lmo2's Oncogenic Function in T-Cell Leukemia Requires Ldb1

Gipfel – a Novel Method for Unbiased Molecular ETV6-RUNX1 Screening of Healthy Newborns

DNA Demethylation By Activation-Induced Cytidine Deaminase in B Cell Lymphoma

Hematopoietic Stem Cells Are Dependent On Homologous Recombination Only During Active Cell Cycle in Nuclease-Mutant Exonuclease1 mut mice

The 3'-5' Exonuclease, TREX1, Interacts with Poly(ADP-ribose) Polymerase-1 (PARP1) in Response to DNA Damage

Whole Genome Sequencing of Four CD34+-Derived iPSC Polycythemia Vera Clones From a Single Female

Exo1 Independent DNA Mismatch Repair Pathway in Hematopoiesis.

High-Resolution Genome Wide Copy Number Alteration (CNA) and Loss of Heterozigosity (LOH) Analysis in Chronic Myeloid Leukemia (CML) Shows That High and Intermediate Sokal Risk Pts (Pts) Have Multiple Losses Targeting Genes Involved in DNA Repair.

Establishment of a Highly Sensitive Allele Specific Wild Type Blocker Polymerase Chain Reaction Followed by Pyrosequencing for Detection of the p.D816V Point Mutation.

BCR/ABL Stimulates WRN Helicase Activity To Facilitate DNA Double-Strand Breaks Repair.

Telomeric Recombination in Lymphocytes Implicates ALT, an Alternative Mechanism for Telomere Length Maintenance, in Normal Human Hematopoietic Cells.

BCR/ABL and Other Oncogenic Fusion Tyrosine Kinases (FTKs) Stimulate Single Strand Annealing (SSA), the Rare and Extremely Unfaithful DNA Double-Strand Break Repair Pathway To Facilitate Genomic Instability in Hematologic Malignancies.

Physical and Functional Association of the MRN Complex with Human Telomerase in Multiple Myeloma.

BCR/ABL Regulates the Expression and Interacts with Werner Syndrome Helicase/Exonuclease To Modulate Its Biochemical Properties.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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