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Journal Articles

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Sylvie Taveirne, Sigrid Wahlen, Wouter Van Loocke, Laura Kiekens, Eva Persyn, Els Van Ammel, Katrien De Mulder, Juliette Roels, Laurentijn Tilleman, Marc Aumercier, Patrick Matthys, Filip Van Nieuwerburgh, Tessa C. C. Kerre, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove, Georges Leclercq
Journal: Blood
Blood (2020) 136 (3): 288–298.
https://doi.org/10.1182/blood.2020005204
Published: 2020
Includes: Supplemental data
Journal Articles

Loss of Phospholipase C Gamma 1 (PLCG1) Impairs AML1-ETO Induced Leukemia Stem Cell Self-Renewal

Tina M. Schnoeder, PhD, Adrian Schwarzer, MD PhD, Florian Perner, MD, Joanna Kirkpatrick, Anna Dolnik, Konstanze Döhner, Patricia Arreba-Tutusaus, PhD, Salam A. Assi, PhD, Claudia Bruedigam, PhD, Carolin Kathner, Theresa Eifert, Marcus Buschbeck, PhD, Monica Nafria I Fedi, Anetta Ptasinska, PhD, Andrew Elefanty, Elizabeth Ng, Holger Bierhoff, PhD, Florian Gras, MD, Georg Matziolis, MD, Klaus-Dieter Fischer, Olaf Heidenreich, Steven W. Lane, MD PhD, Lars Bullinger, Björn von Eyss, PhD, Alessandro Ori, PhD, Constanze Bonifer, PhD, Florian H. Heidel
Journal: Blood
Blood (2019) 134 (Supplement_1): 531.
https://doi.org/10.1182/blood-2019-121996
Published: 2019
Journal Articles

Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure

Yimeng Gao, PhD, Radovan Vasic, MD, Yuanbin Song, MD, Rhea Teng, B.Sc., Rana Gbyli, MS, Giulia Biancon, PhD, Raman Nelakanti, B.Sc., Eriko Kudo, B.Sc., Wei Liu, PhD, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Xiaman Wang, MD PhD, Poorval Joshi, PhD, Burak Dura, PhD, Veronica Lee, Gabriella Viero, PhD, Akiko Iwasaki, PhD, Rong Fan, PhD, Andrew Xiao, PhD, Richard Flavell, PhD, Hua-Bing Li, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 450.
https://doi.org/10.1182/blood-2019-130442
Published: 2019
Journal Articles

The Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding and Represents a Druggable Target

Christophe Desterke, PhD, Sarah Pagliaro, Pharm D, Patricia Hugues, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1632.
https://doi.org/10.1182/blood-2019-124796
Published: 2019
Journal Articles

Interrogating the Role of ASXL1 and JAK2 mutations in Myeloproliferative Neoplasms Utilizing Human Pluripotent Stem Cells

Taylor B. Collins, Stephanie A. Luff, PhD, Luis F.Z. Batista, PhD, Christopher M. Sturgeon, PhD, Stephen T. Oh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2971.
https://doi.org/10.1182/blood-2019-130541
Published: 2019
Journal Articles

Differential Expression of CD49f Discriminates the Independently Emerged Hematopoietic Stem Cells and Erythroid-Biased Progenitors

Ai-Ning Xu, Dan Liu, Yu-Ting Dai, Fan Zhang, Jian Shen, MSc, Cheng-Long Hu, Chun-Hui Xu, Yuan-Liang Zhang, Yin-Yin Xie, Qiu-Hua Huang, Peng-Fei Xu, Lan Wang, Lin Cheng, Jinyan Huang, PhD, Zhu Chen, PhD, Sai-Juan Chen, PhD, Xiao-Jian Sun, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3700.
https://doi.org/10.1182/blood-2019-130429
Published: 2019
Journal Articles

Efficient Ex Vivo Expansion of Highly Purified Human Umbilical Cord Blood-Derived Very Small CD34 + lin - CD45 - Stem Cells into Functional Endothelial Cells in Vitro in Chemically Identified, Feeder Layer-Free Medium Supplemented with Nicotinamide

Alison Domingues, MS, Kamila Bujko, MS, Magdalena Kucia, PhD DSci, Janina Ratajczak, MD PhD DSci, Mariusz Z Ratajczak, MD PhD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 4882.
https://doi.org/10.1182/blood-2019-125819
Published: 2019
Journal Articles

Activated but Not Quiescent Hematopoietic Stem Cells Rely Readily on Glycolysis As Their Main Source of Energy

Tasleem Arif, PhD, Raymond Liang, PhD, Maio Lin, Msc, Svetlana Kalmikova, Msc, Artem Kasianov, PhD, Vijay Menon, PhD, Dmitri Papatsenko, PhD, Saghi Ghaffari, PhD MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 271.
https://doi.org/10.1182/blood-2019-129099
Published: 2019
Journal Articles

F-Deletion Non-Integrating Measles Virus Vector: A Promising Tool for T-Cell Engineering and Naive iPSCs Generation

Jiyuan Liao, PhD, Yasushi Soda, MD PhD, Ai Sugawara, B.Sc., Yoshie Miura, PhD, Takafumi Hiramoto, PhD, Maino Tahara, PhD, Yuto Takishima, M.S., Shohei Miyamoto, PhD, Makoto Takeda, MD PhD, Kenzaburo Tani, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5750.
https://doi.org/10.1182/blood-2019-131593
Published: 2019
Journal Articles

Significant Features of DNA Methylation at Bivalent Promotor and Repressed Polycomb Regions in Pediatric AML-the Jccg Study, JPLSG AML-05-

Genki Yamato, Tomoko Kawai, PhD, Norio Shiba, Yusuke Hara, Kentaro Ohki, MD PhD, Taeko Kaburagi, MD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Akira Shimada, MD PhD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Souichi Adachi, MD PhD, Takashi Taga, MD PhD, Keizo Horibe, MD PhD, Seishi Ogawa, MD PhD, Kenichiro Hata, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2739.
https://doi.org/10.1182/blood-2019-125025
Published: 2019
Journal Articles

Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita

Brief Report
Wilson Chun Fok, Siddharth Shukla, Alexandre Teixeira Vessoni, Kirsten Ann Brenner, Roy Parker, Christopher M. Sturgeon, Luis Francisco Zirnberger Batista
Journal: Blood
Blood (2019) 133 (12): 1308–1312.
https://doi.org/10.1182/blood-2018-11-885368
Published: 2019
Includes: Supplemental data
Journal Articles

Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells

Yong Lei, PhD, Margaret A. Goodell, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2571.
https://doi.org/10.1182/blood-2018-99-116841
Published: 2018
Journal Articles

A Novel Humanized Hemophilia-a Mouse Model to Facilitate Preclinical In Vivo Studies of Human Specific Fviiia-Mimetic Bispecific Antibodies

Wenjing Li, Jianxin Hu, PhD, Nina Leksa, PhD, Maria M Aleman, PhD, Robert Peters, PhD, Joe Salas, PhD, Arjan Van Der Flier, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2458.
https://doi.org/10.1182/blood-2018-99-119012
Published: 2018
Journal Articles

m 6 A Maintains Hematopoietic Stem and Progenitor Cell Identity

Yuanming Cheng, PhD, Hanzhi Luo, PhD, Franco Izzo, PhD, Brian F Pickering, PhD, Ly P Vu, PhD, Alexandra Schurer, BS, Saroj Gourkanti, BA, Samie R. Jaffrey, MD PhD, Dan A. Landau, MD PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 327.
https://doi.org/10.1182/blood-2018-99-117191
Published: 2018
Journal Articles

Efficient Gene Transduction and Reprogramming of Hematopoietic Cells Including T-Cells By Using a Non-Integrating Measles Virus Vector

Jiyuan Liao, PhD, Yasushi Soda, MD PhD, Ai Sugawara, B.Sc., Yoshie Miura, PhD, Takafumi Hiramoto, PhD, Maino Tahara, PhD, Yuto Takishima, M.S., Lisa Hirose, Yasuki Hijikata, MD PhD, Shohei Miyamoto, PhD, Makoto Takeda, MD PhD, Kenzaburo Tani, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3494.
https://doi.org/10.1182/blood-2018-99-120350
Published: 2018
Journal Articles

Human Pluripotent Stem Cell-Derived Blood Cells for Therapies

Dan S Kaufman, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-14.
https://doi.org/10.1182/blood-2018-99-109424
Published: 2018
Journal Articles

SKI Controls MDS-Associated Chronic TGFb Signaling, Aberrant Splicing, and Stem Cell Fitness

David Muench, BS, Kyle Ferchen, BS, Chinavenmeni S. Velu, PhD, Kith Pradhan, PhD, Kashish Chetal, MS, Clemencia Colmenares, PhD, Amit Verma, MD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4350.
https://doi.org/10.1182/blood-2018-99-119441
Published: 2018
Journal Articles

Nearly a Third of Clonal Hematopoiesis-Associated DNMT3A Mutations Reduce Protein Stability and May be Associated with Poorer Prognosis

Yung-Hsin Huang, Ayala Tovy, PhD, Venkatasubramaniam Sundaramurthy, Jianzhong Su, Joanne Hsu, BS, Lian He, Anna Guzman, Yubin Zhou, Alexander Meissner, PhD, Wei Li, Margaret A. Goodell, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1315.
https://doi.org/10.1182/blood-2018-99-115275
Published: 2018
Journal Articles

Direct Binding of BCOR, but Not CBX8, to MLL-AF9 Is Essential for MLL-AF9 Leukemia Via Regulation of the EYA1/SIX1 Gene Network

John H. Bushweller, PhD, Charles Schmidt, Nicholas Achille, Aravinda Kuntimaddi, Adam Boulton, Benjamin Leach, Shubin Zhang, Nancy J. Zeleznik-Le, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1316.
https://doi.org/10.1182/blood-2018-99-111388
Published: 2018
Journal Articles

Micro-RNA Profiling Reveals the Key Role of miR-206 in the Hematopoietic Potential of Human Embryonic and Induced Pluripotent Stem Cells

Stephane Flamant, Jean-Claude Chomel, PharmD PhD, Christophe Desterke, Olivier Feraud, Emilie Gobbo, Maria Teresa Mitjavila-Garcia, Adlen Foudi, Frank Griscelli, Ali G Turhan, MD PhD, Annelise Bennaceur-Griscelli, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1275.
https://doi.org/10.1182/blood-2018-99-110729
Published: 2018