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Journal Articles

Nras Q61R/+ and Kras −/− cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors

Zhi Wen, Grant Yun, Alexander Hebert, Guangyao Kong, Erik A. Ranheim, Remington Finn, Adhithi Rajagoplan, Shuyi Li, Yun Zhou, Mei Yu, Alisa Damnernsawad, Jeroen P. Roose, Joshua J. Coon, Renren Wen, Demin Wang, Jing Zhang

Blood (2021) 137 (23): 3259–3271.

https://doi.org/10.1182/blood.2020009082

Published: 2021

Includes: Supplemental data

Journal Articles

Bai X, Zhang Y, Huang L, et al. The early activation of memory B cells from Wiskott-Aldrich syndrome patients is suppressed by CD19 downregulation. Blood . 2016;128(13):1723-1734.

Blood (2019) 134 (22): 1997.

https://doi.org/10.1182/blood.2019003731

Published: 2019

Journal Articles

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Harold K. Elias, MD, Christina Spevak, PhD, Lavanya Kannan, PhD, Mohamed A.E. Ali, MD PhD, Gaelle H Martin, PhD, Shanmugapriya Selvaraj, MS, William S Eng, Guangjie Zhao, BS, Amanda Ernlund, PhD, Vinagolu Rajasekhar, PhD, Carolien M Woolthuis, MD PhD, Robert J Schneider, PhD, Christopher Y. Park, MD PhD

Blood (2019) 134 (Supplement_1): 1180.

https://doi.org/10.1182/blood-2019-131333

Published: 2019

Journal Articles

Single Cell Transcriptome Mapping of Human Thymopoiesis Reveals a Continuum of Cell States during T-Lineage Specification and Commitment

Justin Le, BS, Vi Luan Ha, PhD, Fan Li, PhD, Virginia Camacho, Sweta Patel, Rob S. Welner, PhD, Chintan Parekh, MBBS

Blood (2019) 134 (Supplement_1): 1183.

https://doi.org/10.1182/blood-2019-129886

Published: 2019

Journal Articles

A Test to Quantify NOTCH Pathway Activity in T Cell Acute Lymphoblastic Leukemia Patients

Kirsten Canté-Barrett, PhD, Laurent Holtzer, PhD, Henk van Ooijen, PhD, Rico Hagelaar, Valentina Cordo', MSc, Wim Verhaegh, PhD, Anja van de Stolpe, MD PhD, Jules P.P. Meijerink, PhD

Blood (2019) 134 (Supplement_1): 4661.

https://doi.org/10.1182/blood-2019-122856

Published: 2019

Journal Articles

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

Chie Suzuki, Tohru Fujiwara, MD PhD, Hiroki Shima, Koya Ono, MD, Kei Saito, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Hisayuki Yokoyama, MD PhD, Shinichi Fujimaki, Yukio Nakamura, MD PhD, Hideo Harigae, MD PhD

Blood (2019) 134 (Supplement_1): 3523.

https://doi.org/10.1182/blood-2019-122618

Published: 2019

Journal Articles

Downregulation of Transcription Factor LRF/ZBTB7A Increases Fetal Hemoglobin Expression in β-Thalassemia/Hemoglobin E Erythroid Cells

Sukanya Chumchuen, MSc, BSc, Tanapat Pornsukjantra, B.Sc., Pinyaphat Khamphikham, PhD, Usanarat Anurathapan, MD, Orapan Sripichai, PhD, Duantida Songdej, Suradej Hongeng, MD

Blood (2019) 134 (Supplement_1): 3549.

https://doi.org/10.1182/blood-2019-126664

Published: 2019

Journal Articles

ASXL1 Mutations Are Associated with Widespread and Distinct DNA Methylation Alterations

Nora E Rahmani, MD, Nandini Ramachandra, Tushar D Bhagat, PhD, Shanisha Gordon, Kith Pradhan, PhD, Bianca Rivera Pena, Mohammad Kazemi, Orsi Giricz, PhD, Shahina Maqbool, Raul Olea, Hamid Dolatshad, Vickram Tittrea, Dharamveer Tatwavedi, Shalini Singh, Andrea Pellagatti, Jacqueline Boultwood, Amit Verma, MBBS

Blood (2019) 134 (Supplement_1): 2989.

https://doi.org/10.1182/blood-2019-126850

Published: 2019

Journal Articles

Class I PI3K Is Required for HSC Differentiation

Kristina Ames, PhD, Imit Kaur, PhD, Meng Tong, Shayda Hemmati, PhD, Ellen Tein, Shira Glushakow-Smith, Lindsay Gurska, Kira Gritsman, MD PhD

Blood (2019) 134 (Supplement_1): 2461.

https://doi.org/10.1182/blood-2019-123823

Published: 2019

Journal Articles

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Wulin Aerbajinai, MD PhD, Jianqiong Zhu, MD, Chutima Kumkhaek, PhD, Kyung Chin, Griffin Rodgers, MD

Blood (2019) 134 (Supplement_1): 2318.

https://doi.org/10.1182/blood-2019-130318

Published: 2019

Journal Articles

Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function

Umapathy N Siddaramappa, PhD, Niren Patel, MBBS, Betty S. Pace, MD, Abdullah Kutlar, MD

Blood (2019) 134 (Supplement_1): 2258.

https://doi.org/10.1182/blood-2019-130924

Published: 2019

Journal Articles

SETDB1 Mediated H3K9 Methylation Suppresses MLL-Fusion Target Expression and Leukemic Transformation

Andrew G. Muntean, PhD, James Ropa, Nirmalya SAHA, PhD MSc, BSc, Hsiang-Yu Hu, BS, Justin Serio, Lili Zhao, Venkatesha Basrur, Alexei Nesvizhskii, Ivan Maillard, MD PhD

Blood (2019) 134 (Supplement_1): 110.

https://doi.org/10.1182/blood-2019-122610

Published: 2019

Journal Articles

Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits

Charu Mehta, MS, Isabela J Fraga de Andrade, Bachelors in Biological Science, Nobuyuki Tanimura, PhD, Gary M Wilson, Erik A. Ranheim, MD PhD, Joshua J Coon, PhD, Emery H Bresnick, PhD

Blood (2019) 134 (Supplement_1): 155.

https://doi.org/10.1182/blood-2019-126917

Published: 2019

Journal Articles

Downregulation of Sprr1a Contributes to the Pathobiology of Sickle Cell Disease

Donovan A Argueta, BSc, Anupam Aich, PhD, Jianxun Lei, PhD, Sergei Nekhai, PhD, Tatiana Ammosova, PhD, Xionghao Lin, PhD, Anindya Bagchi, PhD, Kalpna Gupta, PhD

Blood (2019) 134 (Supplement_1): 75.

https://doi.org/10.1182/blood-2019-129004

Published: 2019

Journal Articles

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

Sohaila Mohamed Khalil, Swagata Goswami, MSc, Xiaokui Mo, PhD MAS, Natarajan Muthusamy, DVM,PhD

Blood (2019) 134 (Supplement_1): 3977.

https://doi.org/10.1182/blood-2019-129224

Published: 2019

Journal Articles

A GPI-Anchored Protein, CD109, Protects Hematopoietic Progenitor Cells from Erythroid Differentiation Induced By TGF-β

Tanabe Mikoto, MD, Nguyen Hoang Maianh, MD, Kohei Hosokawa, MD PhD, Noriharu Nakagawa, MD, Luis Espinoza, MD PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2019) 134 (Supplement_1): 3736.

https://doi.org/10.1182/blood-2019-126677

Published: 2019

Journal Articles

The Ire of IRE1α: Overexpression of IRE1α at Myeloma Diagnosis Is Associated with Decreased Survival While Downregulation of IRE1α Expression Is Predictive of Therapy Resistance

Scott R. Goldsmith, MD, Mark A. Fiala, BS, Mark A. Schroeder, MD, Tanya M. Wildes, MD, Armin Ghobadi, MD, Ravi Vij, MBBS, Keith E. Stockerl-Goldstein, MD

Blood (2019) 134 (Supplement_1): 4351.

https://doi.org/10.1182/blood-2019-131135

Published: 2019

Journal Articles

Downregulation of MDM2 Leads to Anti-Proliferative Effects through Activation of p53-Associated Pathway Mediated By Both Dual Inhibitor MX69 and Mir-548c-3p in Multiple Myeloma

Faruq Faruq, PhD, Davidson Zhao, Jian Wu, MD, Jonahunnatha Nesson George William, PhD, Min Zhang, MD, Hong Chang, MD

Blood (2019) 134 (Supplement_1): 4419.

https://doi.org/10.1182/blood-2019-129430

Published: 2019

Journal Articles

Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations

Sravanti Rangaraju, MBBS, Silvia Marino, PhD, G. David Roodman, MD PhD, Larry D. Cripe, MD, Baskar Ramdas, PhD, Lakshmi Reddy Palam, PhD, Katie J Sargent, RN, Hamid Sayar, MD MSc, Heiko Konig, MD PhD, Reuben Kapur, PhD, H. Scott Boswell, MD

Blood (2019) 134 (Supplement_1): 5051.

https://doi.org/10.1182/blood-2019-124384

Published: 2019

Journal Articles

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

Meixian Huang, Amit Verma, MBBS, Ke Zeng, MD PhD, Mi-Ae Lyu, PhD, Mitsutaka Nishimoto, MD PhD, Hongbing Ma, MD PhD, Zheng Yin, PhD, Swaminathan P. Iyer, MD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 4446.

https://doi.org/10.1182/blood-2019-131948

Published: 2019

NARROW

Nras Q61R/+ and Kras −/− cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors

Bai X, Zhang Y, Huang L, et al. The early activation of memory B cells from Wiskott-Aldrich syndrome patients is suppressed by CD19 downregulation. Blood . 2016;128(13):1723-1734.

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Single Cell Transcriptome Mapping of Human Thymopoiesis Reveals a Continuum of Cell States during T-Lineage Specification and Commitment

A Test to Quantify NOTCH Pathway Activity in T Cell Acute Lymphoblastic Leukemia Patients

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

Downregulation of Transcription Factor LRF/ZBTB7A Increases Fetal Hemoglobin Expression in β-Thalassemia/Hemoglobin E Erythroid Cells

ASXL1 Mutations Are Associated with Widespread and Distinct DNA Methylation Alterations

Class I PI3K Is Required for HSC Differentiation

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function

SETDB1 Mediated H3K9 Methylation Suppresses MLL-Fusion Target Expression and Leukemic Transformation

Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits

Downregulation of Sprr1a Contributes to the Pathobiology of Sickle Cell Disease

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

A GPI-Anchored Protein, CD109, Protects Hematopoietic Progenitor Cells from Erythroid Differentiation Induced By TGF-β

The Ire of IRE1α: Overexpression of IRE1α at Myeloma Diagnosis Is Associated with Decreased Survival While Downregulation of IRE1α Expression Is Predictive of Therapy Resistance

Downregulation of MDM2 Leads to Anti-Proliferative Effects through Activation of p53-Associated Pathway Mediated By Both Dual Inhibitor MX69 and Mir-548c-3p in Multiple Myeloma

Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

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American Society of Hematology

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American Society of Hematology

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