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Gabriella De Canal
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Journal Articles

Progressive Down Regulation of JAK-STAT, Cell Cycle, and ABC Transporter Genes in CD34+/Lin- Cells of Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients at Diagnosis Vs. 12 Months of Nilotinib Treatment Vs. Healthy Subjects

Alessandra Trojani, Ester Pungolino, Giuseppe Rossi, Mariella D'adda, Luca Emanuele Bossi, Giacomo Baruzzo, Barbara Di Camillo, Alessandra Perego, Mauro Turrini, Chiara Elena, MD, Lorenza Maria Borin, Alessandra Iurlo, MD PhD, Simona Malato, Francesco Spina, Maria Luisa Latargia, Pierangelo Spedini, Salvatore Artale, Michela Anghilieri, Maria Cristina Carraro, Cristina Bucelli, Gabriella De Canal, Enrica Morra, Roberto Cairoli, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5034.
https://doi.org/10.1182/blood-2019-125595
Published: 2019
Journal Articles

Nilotinib Deregulates Cell Cycle Checkpoints, ABC Transporters Genes and JAK-STAT Signaling Pathway of CD34+/Lin- Cells in Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients after 12 Months of Treatment

Alessandra Trojani, PhD, Ester Pungolino, Giuseppe Rossi, MD, Mariella D'adda, MD, Milena Lodola, PhD, Alessandra Dal Molin, PhD, Giacomo Baruzzo, PhD, Alessandra Perego, MD, Mauro Turrini, MD, Chiara Elena, MD, Lorenza Maria Borin, MDcal doctor, Alessandra Iurlo, Simona Malato, MD, Francesco Spina, MD, Maria Luisa Latargia, MD, Pierangelo Spedini, MD, Salvatore Artale, MD, Michela Anghilieri, MD, Carraro Maria Cristina, MD, Cristina Bucelli, MD, Gabriella De Canal, PhD, Enrica Morra, MD, Roberto Cairoli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5122.
https://doi.org/10.1182/blood-2018-99-112188
Published: 2018
Journal Articles

Jak-2 and Nfkbia G ene Expression Play a Strategic Role in Chronic Myeloid Leukemia (CML) Molecular Response during Early Nilotinib Treatment: The PhilosoPhi34 Data

Ester Pungolino, Mariella D'adda, MD, Alessandra Trojani, PhD, Alessandra Perego, MD, Chiara Elena, MD, Alessandra Iurlo, Simona Malato, MD, Mauro Turrini, MD, Gabriella De Canal, PhD, Lorenza Borin, MD, Milena Lodola, PhD, Marianna Caramella, MD, Salvatore Artale, MD, Francesco Spina, MD, Maria Luisa Latargia, MD, Michela Anghilieri, MD, Pierangelo Spedini, MD, Mariacristina Carraro, Barbara Di Camillo, Doriana Gramegna, MD, Maria Luisa Pioltelli, MD, Giuseppe Rossi, MD, Enrica Morra, MD, Roberto Cairoli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5118.
https://doi.org/10.1182/blood-2018-99-113273
Published: 2018
Journal Articles

Gene Expression Profiling and Cellularity of Bone Marrow CD34+/Lin- Cells of Patients with Chronic-Phase Chronic Myeloid Leukemia at Diagnosis Vs. 12 Months of First-Line Nilotinib Treatment

Alessandra Trojani, Ester Pungolino, Giuseppe Rossi, MD, Mariella D'Adda, MD, Milena Lodola, Barbara Di Camillo, Alessandra Perego, MD, Mauro Turrini, MD, Ester Maria Orlandi, MD, Lorenza Maria Borin, MD, Alessandra Iurlo, MD PhD, Simona Malato, MD, Francesco Spina, MD, Maria Luisa Latargia, MD, Francesco Lanza, Salvatore Artale, Michela Anghilieri, MD, Carraro Maria Cristina, MD, Cristina Bucelli, MD, Gabriella De Canal, Enrica Morra, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4973.
https://doi.org/10.1182/blood.V130.Suppl_1.4973.4973
Published: 2017
Journal Articles

The REL-Protocol PhilosoPhi34 - an Open Label, Single Arm, Phase II Study of Nilotinib 300 Mg BID in Newly Diagnosed Chronic Phase Chronic Myeloid Leukaemia (CML) Patients - Confirms Early Clearance of Bone Marrow CD34+/Lin-Ph+ Cells

Ester Pungolino, MD, Gabriella De Canal, Mariella D'adda, MD, Alessandra Perego, MD, Mauro Turrini, MD, Ester Maria Orlandi, MD, Alessandra Trojani, PhD, Lorenza Borin, MD, Alessandra Iurlo, MD, Maria Luisa Latargia, MD, Simona Malato, MD, Maria Cristina Carraro, MD, Stefania Brusorio, Chiara Elena, MD, Francesco Spina, MD, Milena Lodola, Salvatore Artale, MD, Michela Anghilieri, MD, Cristina Bucelli, MD, Maria Luisa Pioltelli, MD, Silvia Cantoni, MD, Giuseppe Rossi, MD, Enrica Morra, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2016) 128 (22): 3080.
https://doi.org/10.1182/blood.V128.22.3080.3080
Published: 2016
Journal Articles

REL-Protocol PhilosoPhi34: An Open Label, Single Arm, Phase II Study of Nilotinib 300 Mg BID in Newly Diagnosed Chronic Phase Chronic Myeloid Leukaemia Patients, to Study the Disappearance of CD34+/Lin-Ph+ Cells from Bone Marrow during Treatment. Preliminary Data

Ester Pungolino, MD, Giuseppe Rossi, MD, Maria Angela Mura, Alessandra Perego, MD, Ester Maria Orlandi, MD, Mauro Turrini, MD, Lorenza Borin, MD, Maria Adele Capucci, MD, Alessandra Iurlo, MD PhD, Alessandra Trojani, PhD, Mariella D'Adda, MD, Francesco Spina, MD, Gabriella De Canal, Maria Luisa Pioltelli, Maria Luisa Latargia, MD, Sergio Pauli, MD, Chiara Elena, MD, Stefania Brusorio, Francesco Lanza, MD, Simona Malato, MD, Michela Anghilieri, MD, Maria C Carraro, MD, Enrica Morra, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2015) 126 (23): 1597.
https://doi.org/10.1182/blood.V126.23.1597.1597
Published: 2015
Journal Articles

Comparison Between FISH and Immunostimulatory Oligonucleotide-Induced Metaphase Cytogenetics in Previously Untreated CLL: Impact on Prognosis

Alessandra Tedeschi, Mariangela Mura, Eleonora Vismara, Silvia Soriani, Francesca Ricci, Elisa Roncoroni, Gabriella De Canal, Michele Nichelatti, Enrica Morra, Marco Montillo
Journal: Blood
Blood (2011) 118 (21): 4587.
https://doi.org/10.1182/blood.V118.21.4587.4587
Published: 2011