Page 1 | Search Results | Blood | American Society of Hematology

1-18 of 18

Sort by

Sort Order Select

Journal Articles

A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the γ-globin gene in β-thalassemia

Yi Gong, Xinhua Zhang, Qianqian Zhang, Yanxia Zhang, Yuhua Ye, Wenxia Yu, Congwen Shao, Tizhen Yan, Jin Huang, Jianmei Zhong, Li Wang, Yaoyun Li, Liren Wang, Xiangmin Xu

Blood (2021) 137 (12): 1652–1657.

https://doi.org/10.1182/blood.2020006425

Published: 2021

Includes: Supplemental data

Journal Articles

CDK8 Inhibitors Induce Transcriptional Reprogramming of AML Cells Associated with Differentiation

Milena Mazan, PhD, Marion Chapellier, PhD, Marcus Järås, PhD, Michal Mikula, MD PhD, Eliza Majewska, PhD, Katarzyna Wiklik, PhD, Michal Combik, PhD, Aniela Golas, PhD, Magdalena Masiejczyk, MSc, Elzbieta Fiedor, MSc, Federico Malusa, MSc, Przemyslaw Juszczynski, Prof., MD PhD, Magdalena Cybulska, DVM, Maciej Mikulski, PhD, Jerzy Ostrowski, Prof., MD PhD, Pawel Chrom, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD

Blood (2019) 134 (Supplement_1): 3774.

https://doi.org/10.1182/blood-2019-128073

Published: 2019

Journal Articles

Dual Effects of BCOR-PRC1.1 Dependent Gene Regulation Mediate Cooperation of BCOR and TET2 Mutations in Myeloid Transformation

Eva Johanna Schaefer, MD, Iman Fares, PhD, Clifford Meyer, PhD, Paloma Cejas, PhD, Annie Apffel, BA, Monica Schenone, PhD, Henry W Long, PhD, R. Coleman Lindsley, MD PhD

Blood (2018) 132 (Supplement 1): 651.

https://doi.org/10.1182/blood-2018-99-119519

Published: 2018

Journal Articles

Modeling ASXL1 Mutation Revealed Myelodysplasia Caused By Derepression of p16Ink4a through Aberrant PRC1-Mediated Histone Modification

Masahiro Uni, MD PhD, Yosuke Masamoto, MD PhD, Tomohiko Sato, MD PhD, Shunya Arai, MD PhD, Eiji Hara, PhD, Mineo Kurokawa, MD PhD

Blood (2017) 130 (Supplement 1): 118.

https://doi.org/10.1182/blood.V130.Suppl_1.118.118

Published: 2017

Journal Articles

Endogenous Retrovirus Derepression Drives Ectopic UGT2B17 Overexpression in Multiple Myeloma Cells: Molecular Sequelae and Pathophysiological Implications

Spyros Ioannis Papamichos, MD PhD, Eleftheria Lamprianidou, Chryssoula Kordella, Emmanouil Spanoudakis, Menelaos Konstantinos Papoutselis, Ioannis Kotsianidis, PhD

Blood (2017) 130 (Supplement 1): 4978.

https://doi.org/10.1182/blood.V130.Suppl_1.4978.4978

Published: 2017

Journal Articles

The Cohesin Subunit Rad21 Is a Negative Regulator of Hematopoietic Self-Renewal through Epigenetic Repression of HoxA7 and HoxA9

Joseph B. Fisher, PhD, Jonathan Peterson, B.S., Michael Reimer, Jr., B.S., Cary Stelloh, BA, Kirthi Pulakanti, MS, Zachary Gerbec, BS, Alex M Abel, MS, Jennifer Strouse, MD, Christopher Strouse, MD, Maureen McNulty, BS, Subramaniam Malarkannan, PhD, John Crispino, PhD MBA, Samuel Milanovich, MD, Sridhar Rao, MD PhD

Blood (2016) 128 (22): 1708.

https://doi.org/10.1182/blood.V128.22.1708.1708

Published: 2016

Journal Articles

Mitochondria Coordinate Intracellular Metabolism and Epigenetic Gene Regulation during Erythropoiesis

Xin Liu, PhD, Yuannyu Zhang, PhD, Min Ni, PhD, Hui Cao, M.S., Robert Signer, PhD, Dan Li, B.S., Zhimin Gu, PhD, Zeping Hu, PhD, Navdeep Chandel, Ralph DeBerardinis, MD PhD, Feng Zhou, PhD, Zhen Shao, PhD, Jian Xu, PhD

Blood (2016) 128 (22): 1038.

https://doi.org/10.1182/blood.V128.22.1038.1038

Published: 2016

Journal Articles

MIR142 Loss-of-Function Mutations Promote Leukemogenesis through Derepression of ASH1L Resulting in Increased HOX Gene Expression

Juo-Chin Yao, BS, Terrence Neal Wong, MD PhD, Maria Trissal, MD PhD, Rahul Ramaswamy, Yaping Sun, MD PhD, Timothy J. Ley, MD, Pavan R. Reddy, MD, Daniel C. Link, MD

Blood (2016) 128 (22): 2718.

https://doi.org/10.1182/blood.V128.22.2718.2718

Published: 2016

Journal Articles

Transcriptional Control of HSC Fitness

David E. Muench, MEng, Chinavenmeni S. Velu, PhD, Andre Olsson, PhD, Sara E. Meyer, PhD, H. Leighton Grimes, PhD

Blood (2015) 126 (23): 1161.

https://doi.org/10.1182/blood.V126.23.1161.1161

Published: 2015

Journal Articles

A Patient-Derived EZH2 Mutant Induces MDS-like Diseases with Derepressed ABCG2 Expression in Mice

Kimihito Cojin Kawabata, MD PhD, Daichi Inoue, MD PhD, Jiro Kitaura, MD PhD, Yuka Harada, MD PhD, Susumu Goyama, MD PhD, Hironori Harada, MD PhD, Hiroyuki Aburatani, MD PhD, Toshio Kitamura, MD PhD

Blood (2015) 126 (23): 4116.

https://doi.org/10.1182/blood.V126.23.4116.4116

Published: 2015

Journal Articles

Targeting The PRMT5 Enzyme To Induce γ -Globin Gene Derepression In Sickle Cell Anemia

Necrisha Roach, MSc., Matthew Cannon, Dalia El-Gamal, PhD, Payal C Desai, MD, Eric H. Kraut, MD, James E. Bradner, M.D., Rosa Lapalombella, PhD, Robert A. Baiocchi, M.D., Ph.D.

Blood (2013) 122 (21): 1007.

https://doi.org/10.1182/blood.V122.21.1007.1007

Published: 2013

Journal Articles

SQSTM1/p62 Is a Necessary Cofactor In MDS/AML With Deletion Of Mir-146a

Jing Fang, MD/PhD, Brenden Barker, BSc, Lyndsey Bolanos, BSc, Xiaona Liu, BSc, Andres Jerez, MD, PhD, Hideki Makishima, MD, PhD, Dinesh S. Rao, M.D., James C. Mulloy, PhD, Jaroslaw P. Maciejewski, MD, PhD, Jose A. Cancelas, M.D. PhD., Daniel T Starczynowski, PhD

Blood (2013) 122 (21): 747.

https://doi.org/10.1182/blood.V122.21.747.747

Published: 2013

Journal Articles

Loss Of Canonic Notch Signaling In The Microenvironment Causes a Myeloproliferative Syndrome Via Derepression Of The miR155 Promoter

Lin Wang, PhD, Huajia Zhang, BS, Sonia Rodriguez-Rodriguez, PhD, Liyun Cao, PhD, Jonathan Parish, BS, Amy Zollman, BS, Malgorzata Kamocka, PhD, H. Scott Boswell, M.D., Edward F. Srour, Ph.D., Brahmananda Reddy Chitteti, PhD, Taghi Manshouri, Ph.D., Srdan Verstovsek, MD, PhD, Reuben Kapur, PhD, Angelo A. Cardoso, MD, PhD, Nadia Carlesso, MD, PhD

Blood (2013) 122 (21): 339.

https://doi.org/10.1182/blood.V122.21.339.339

Published: 2013

Journal Articles

MLL-ENL Inhibits Polycomb Repressive Complex 1 to Achieve Efficient Transformation of Hematopoietic Cells

Emanuel Maethner, Constanze Breitinger, Maria-Paz Garcia-Cuellar, Ph.D., Jay L. Hess, MD, PhD, Robert K. Slany, PhD

Blood (2011) 118 (21): 2443.

https://doi.org/10.1182/blood.V118.21.2443.2443

Published: 2011

Journal Articles

Haploinsufficiency of Dnmt1 Impairs Leukemia Stem Cell Function Through Derepression of Bivalent Chromatin Domains,

Jennifer J. Trowbridge, PhD, Amit U. Sinha, Scott A. Armstrong, MD, PhD, Stuart H. Orkin, MD

Blood (2011) 118 (21): 3459.

https://doi.org/10.1182/blood.V118.21.3459.3459

Published: 2011

Journal Articles

LSD1-Mediated Epigenetic Modification Is Important for TAL1 Function

Xin Hu, Xingguo Li, PhD, River Ybarra, Kristell Valverde, Xueqi Fu, Constance Noguchi, PhD, Yi Qiu, PhD, Suming Huang, PhD

Blood (2008) 112 (11): 4757.

https://doi.org/10.1182/blood.V112.11.4757.4757

Published: 2008

Journal Articles

GATA1s Mutant Protein Contributes to “Down” Syndrome Megakaryoblastic Leukemia by Derepression of E2F Targets.

Jan-Henning Klusmann, MD, Frank Godinho, Thanaseelan Pushpanathan, Dirk Reinhardt, MD, PhD, Stuart H Orkin, MD, Zhe Li, PhD

Blood (2008) 112 (11): 2248.

https://doi.org/10.1182/blood.V112.11.2248.2248

Published: 2008

Journal Articles

CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus

Ling Zhao, Jennifer L. Cannons, Stacie Anderson, Martha Kirby, Liping Xu, Lucio H. Castilla, Pamela L. Schwartzberg, Rémy Bosselut, P. Paul Liu

Blood (2006) 109 (8): 3432–3440.

https://doi.org/10.1182/blood-2006-10-051508

Published: 2006

Includes: Supplemental data

NARROW

A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the γ-globin gene in β-thalassemia

CDK8 Inhibitors Induce Transcriptional Reprogramming of AML Cells Associated with Differentiation

Dual Effects of BCOR-PRC1.1 Dependent Gene Regulation Mediate Cooperation of BCOR and TET2 Mutations in Myeloid Transformation

Modeling ASXL1 Mutation Revealed Myelodysplasia Caused By Derepression of p16Ink4a through Aberrant PRC1-Mediated Histone Modification

Endogenous Retrovirus Derepression Drives Ectopic UGT2B17 Overexpression in Multiple Myeloma Cells: Molecular Sequelae and Pathophysiological Implications

The Cohesin Subunit Rad21 Is a Negative Regulator of Hematopoietic Self-Renewal through Epigenetic Repression of HoxA7 and HoxA9

Mitochondria Coordinate Intracellular Metabolism and Epigenetic Gene Regulation during Erythropoiesis

MIR142 Loss-of-Function Mutations Promote Leukemogenesis through Derepression of ASH1L Resulting in Increased HOX Gene Expression

Transcriptional Control of HSC Fitness

A Patient-Derived EZH2 Mutant Induces MDS-like Diseases with Derepressed ABCG2 Expression in Mice

Targeting The PRMT5 Enzyme To Induce γ -Globin Gene Derepression In Sickle Cell Anemia

SQSTM1/p62 Is a Necessary Cofactor In MDS/AML With Deletion Of Mir-146a

Loss Of Canonic Notch Signaling In The Microenvironment Causes a Myeloproliferative Syndrome Via Derepression Of The miR155 Promoter

MLL-ENL Inhibits Polycomb Repressive Complex 1 to Achieve Efficient Transformation of Hematopoietic Cells

Haploinsufficiency of Dnmt1 Impairs Leukemia Stem Cell Function Through Derepression of Bivalent Chromatin Domains,

LSD1-Mediated Epigenetic Modification Is Important for TAL1 Function

GATA1s Mutant Protein Contributes to “Down” Syndrome Megakaryoblastic Leukemia by Derepression of E2F Targets.

CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only