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Journal Articles

Pediatric hemophagocytic lymphohistiocytosis

Scott W. Canna, Rebecca A. Marsh

Blood (2020) 135 (16): 1332–1343.

https://doi.org/10.1182/blood.2019000936

Published: 2020

Journal Articles

Decline in Insulin-like Growth Factor-1 (IGF1) from Aged Mesenchymal Stromal Cells Is a Targetable Mechanism to Rescue Hematopoietic Stem Cell Aging

Kira Young, PhD, Elizabeth Eudy, BS, Matthew Loberg, BA, Rebecca Bell, BA, Jennifer Trowbridge, PhD

Blood (2019) 134 (Supplement_1): 526.

https://doi.org/10.1182/blood-2019-124534

Published: 2019

Journal Articles

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

Qiu-Sha Huang, Jing Xue, Chen-Cong Wang, Ya-Zhen Qin, Lan-Ping Xu, Kaiyan Liu, Xiao-Jun Huang, MD, Xiao-Hui Zhang

Blood (2019) 134 (Supplement_1): 218.

https://doi.org/10.1182/blood-2019-126384

Published: 2019

Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD

Blood (2019) 134 (Supplement_1): 99.

https://doi.org/10.1182/blood-2019-125359

Published: 2019

Journal Articles

The Role of the Lipid Raft-Associated Protein Flotillin-2 during Development and Progression of Myeloid Leukaemia

Rahul Kumar, PhD, Raquel Pereira, M.Sc, Julian Niemann, Costanza Zanetti, MSc, Alex Azimpour, Melanie Meister, PhD, Parimala Sonika Godavarthy, MSc, Daniela S. Krause, MD

Blood (2019) 134 (Supplement_1): 2921.

https://doi.org/10.1182/blood-2019-122670

Published: 2019

Journal Articles

A Stemness Screen Reveals C3ORF54/INKA1 As a Gate-Keeper of Human Stem Cell Latency

Kerstin B. Kaufmann, PhD, Laura Garcia Prat, Shin-Ichiro Takayanagi, PhD, Jessica McLeod, BSc, Olga I. Gan, Kristele Pan, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD

Blood (2018) 132 (Supplement 1): 325.

https://doi.org/10.1182/blood-2018-99-115065

Published: 2018

Journal Articles

Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α

Shailaja N Hegde, PhD, Mark J Althoff, BS, Ramesh C. Nayak, PhD, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Gang Huang, PhD, Yi Zheng, PhD, Maria T Diaz-Meco, PhD, Jorge Moscat, PhD, Jose A Cancelas, MD PhD

Blood (2018) 132 (Supplement 1): 551.

https://doi.org/10.1182/blood-2018-99-118919

Published: 2018

Journal Articles

Aged murine hematopoietic stem cells drive aging-associated immune remodeling

Hanna Leins, Medhanie Mulaw, Karina Eiwen, Vadim Sakk, Ying Liang, Michael Denkinger, Hartmut Geiger, Reinhold Schirmbeck

Blood (2018) 132 (6): 565–576.

https://doi.org/10.1182/blood-2018-02-831065

Published: 2018

Includes: Supplemental data

Journal Articles

Transcriptional Regulation of the CDC42 Signaling Pathway By Ikaros in T-Cell Acute Lymphoblastic Leukemia

Sinisa Dovat, Zheng Ge, MD PhD, Kimberly Payne, Chandrika Gowda, MD, Chunhua Song, MD

Blood (2017) 130 (Supplement 1): 1213.

https://doi.org/10.1182/blood.V130.Suppl_1.1213.1213

Published: 2017

Journal Articles

PAK4 Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldestrostom Macroglobulinemia

Na Li, MD, Mariateresa Fulciniti, PhD, Michael A Lopez, BS, Tommaso Perini, MD, Raphael Szalat, MD, Subodh Kumar, PhD, Mehmet Kemal Samur, PhD, Lian Xu, Yan Xu, MD, William Senapedis, PhD, Erkan Baloglu, Stefania Oliva, MD, Masood A. Shammas, PhD, Zachary Hunter, PhD, Kenneth C Anderson, MD, Steven P Treon, MDPhDFRCP, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 648.

https://doi.org/10.1182/blood.V130.Suppl_1.648.648

Published: 2017

Journal Articles

The cell polarity determinant CDC42 controls division symmetry to block leukemia cell differentiation

Benjamin Mizukawa, Eric O’Brien, Daniel C. Moreira, Mark Wunderlich, Cindy L. Hochstetler, Xin Duan, Wei Liu, Emily Orr, H. Leighton Grimes, James C. Mulloy, Yi Zheng

Blood (2017) 130 (11): 1336–1346.

https://doi.org/10.1182/blood-2016-12-758458

Published: 2017

Includes: Supplemental data

Journal Articles

Palladin Regulates Receptor Clustering and Actin Dynamics in Phagocytosis

Haimin Sun, PhD, Xinlei Chen, Jiang Zhu, MD PhD, Zhu Chen, Saijuan Chen

Blood (2016) 128 (22): 2505.

https://doi.org/10.1182/blood.V128.22.2505.2505

Published: 2016

Journal Articles

Alterations of Signaling Pathways in Essential Thrombocythemia with Calreticulin Mutation

Wuhan Hui, PhD, Fei Ye, Wei Zhang, Congyan Liu, Suigui Wan, Li Su

Blood (2016) 128 (22): 4286.

https://doi.org/10.1182/blood.V128.22.4286.4286

Published: 2016

Journal Articles

Vav1, a Rho GTPase Guanine Exchange Factor (GEF) Is Required to Integrate gp130 Cytokine Signaling for Successful Engraftment of Murine Hematopoietic Stem Cells Following Irradiation

Serena De Vita, MD PhD, Yanhua Li, MD PhD, Chad Everett Harris, MS, Meaghan McGuinness, BS, David A. Williams, MD

Blood (2016) 128 (22): 2149.

https://doi.org/10.1182/blood.V128.22.2149.2149

Published: 2016

Journal Articles

Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma

Deepak Perumal, PhD, Alessandro Lagana', PhD, David Melnekoff, BS, Ben Readhead, MBBS, Brian Kidd, PhD, Violetta V Leshchenko, PhD, Pei-Yu Kuo, MS, Jennifer Yesil, MS, Mary Derome, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2016) 128 (22): 802.

https://doi.org/10.1182/blood.V128.22.802.802

Published: 2016

Journal Articles

p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix

Pavankumar N. G. Reddy, Maria Radu, Ke Xu, Jenna Wood, Chad E. Harris, Jonathan Chernoff, David A. Williams

Blood (2016) 127 (16): 1967–1975.

https://doi.org/10.1182/blood-2016-01-693572

Published: 2016

Journal Articles

Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice

Ramesh Choudhari, Valerio Giacomo Minero, Matteo Menotti, Roberta Pulito, Cord Brakebusch, Mara Compagno, Claudia Voena, Chiara Ambrogio, Roberto Chiarle

Blood (2016) 127 (10): 1297–1306.

https://doi.org/10.1182/blood-2015-11-683052

Published: 2016

Includes: Supplemental data

Journal Articles

XRCC5 Plays an Important Role in Homologous Recombination, Genome Stability and Survival of Myeloma Cells

Edward Laane, MD PhD, Purushothama Nanjappa, Subodh Kumar, PhD, Florence Magrangeas, Stephane Minvielle, Hele Everaus, MD PhD, Kenneth C Anderson, MD, Herve Avet-Loiseau, Masood A Shammas, PhD, Nikhil C. Munshi, MD

Blood (2015) 126 (23): 1218.

https://doi.org/10.1182/blood.V126.23.1218.1218

Published: 2015

Journal Articles

In Vitro and In Vivo Anti-Leukemic Effects of KPT-9274, a Reported PAK4 Allosteric Modulator, in Acute Myeloid Leukemia: Promising Results Justifying Further Development in This Disease

Shaneice Mitchell, BS, Shelley Orwick, BS, Matthew Cannon, BS, Virginia M. Goettl, DVM , PhD, Taylor D. LaFollette, Erkan Baloglu, PhD, William Senapedis, PhD, Alison R. Walker, MD, Bhavana Bhatnagar, Alice S. Mims, MD, Rebecca B. Klisovic, MD, Sumithira Vasu, MBBS, William Blum, MD, David M. Lucas, PhD, James S. Blachly, MD, Ramiro Garzon, MD, Clara D. Bloomfield, MD, Rosa Lapalombella, PhD, John C. Byrd, MD

Blood (2015) 126 (23): 2471.

https://doi.org/10.1182/blood.V126.23.2471.2471

Published: 2015

Journal Articles

EphB4/EphrinB2 Contributes to Imatinib Resistance in Chronic Myeloid Leukemia Involved in Cytoskeletal Proteins

Lin Li, Na Xu, MD, Xuan Zhou, MD, Yuling Li, Qisi Lu, Ziyuan Lu, Jixian Huang, Bolin He, Chengyun Pan, Qifa Liu, MD, Liu Xiaoli, MD

Blood (2015) 126 (23): 5135.

https://doi.org/10.1182/blood.V126.23.5135.5135

Published: 2015

NARROW

Pediatric hemophagocytic lymphohistiocytosis

Decline in Insulin-like Growth Factor-1 (IGF1) from Aged Mesenchymal Stromal Cells Is a Targetable Mechanism to Rescue Hematopoietic Stem Cell Aging

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

The Role of the Lipid Raft-Associated Protein Flotillin-2 during Development and Progression of Myeloid Leukaemia

A Stemness Screen Reveals C3ORF54/INKA1 As a Gate-Keeper of Human Stem Cell Latency

Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α

Aged murine hematopoietic stem cells drive aging-associated immune remodeling

Transcriptional Regulation of the CDC42 Signaling Pathway By Ikaros in T-Cell Acute Lymphoblastic Leukemia

PAK4 Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldestrostom Macroglobulinemia

The cell polarity determinant CDC42 controls division symmetry to block leukemia cell differentiation

Palladin Regulates Receptor Clustering and Actin Dynamics in Phagocytosis

Alterations of Signaling Pathways in Essential Thrombocythemia with Calreticulin Mutation

Vav1, a Rho GTPase Guanine Exchange Factor (GEF) Is Required to Integrate gp130 Cytokine Signaling for Successful Engraftment of Murine Hematopoietic Stem Cells Following Irradiation

Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma

p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix

Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice

XRCC5 Plays an Important Role in Homologous Recombination, Genome Stability and Survival of Myeloma Cells

In Vitro and In Vivo Anti-Leukemic Effects of KPT-9274, a Reported PAK4 Allosteric Modulator, in Acute Myeloid Leukemia: Promising Results Justifying Further Development in This Disease

EphB4/EphrinB2 Contributes to Imatinib Resistance in Chronic Myeloid Leukemia Involved in Cytoskeletal Proteins

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American Society of Hematology

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ASH Publications

American Society of Hematology

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