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Journal Articles

Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells

Yong Lei, PhD, Margaret A. Goodell, PhD

Blood (2018) 132 (Supplement 1): 2571.

https://doi.org/10.1182/blood-2018-99-116841

Published: 2018

Journal Articles

Lessons from Nature: A Novel Class of TET Inhibitors for TET2 Mutant Associated Diseases

Yihong Guan, Anand D. Tiwari, PhD, Metis Hasipek, PhD, Dale Grabowski, BS, Yvonne Parker, Cassandra M. Hirsch, Amy C Graham, BS, MS, Yasunobu Nagata, Bartlomiej P. Przychodzen, Aziz Nazha, Daniel Lindner, MD PhD, Tomas Radivoyevitch, PhD, James G Phillips, PhD, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2018) 132 (Supplement 1): 4345.

https://doi.org/10.1182/blood-2018-99-117186

Published: 2018

Journal Articles

The Role and Therapeutic Target of Base Excision Repair Genes in Multiple Myeloma (MM)

Rumi Ino, Takayuki Saitoh, MD PhDProf, Yuya Kitamura, Kazuki Homma, Noriyuki Takahashi, Gotoh Nanami, Master, Tetsuhiro Kasamatsu, PhD, Hiroaki Shimizu, MD PhD, Makiko Takizawa, PhDMD, Morio Matsumoto, MD, Morio Sawamura, MD PhD, Akihiko Yokohama, MD PhD, Norifumi Tsukamoto, MDPhDChief Division, Hiroshi Handa, MD PhDChief Division, Hirokazu Murakami, MDPhDProf

Blood (2017) 130 (Supplement 1): 4403.

https://doi.org/10.1182/blood.V130.Suppl_1.4403.4403

Published: 2017

Journal Articles

Genetic Ablation or Pharmacological Inhibition of PRMT5 Affects Maintenance of Genomic Integrity in Hematopoietic Stem Cells

Darren Qiancheng Tan, BS, Desmond Wai Loon Chin, PhD, Ying Li, Ayako Nakamura-Ishizu, MD PhD, Henry Yang, PhD, Toshio Suda, MDPhD

Blood (2017) 130 (Supplement 1): 711.

https://doi.org/10.1182/blood.V130.Suppl_1.711.711

Published: 2017

Journal Articles

Base Excision Repair Gene OGG1 Affects the Relapse Risk of Acute Myeloid Leukemia

Nanami Gotoh, Takayuki Saitoh, MD PhD, Noriyuki Takahashi, Rumi Ino, Yuya Kitamura, Kazuki Honma, Tomomi Nagashima, Tetsuhiro Kasamatsu, Takumi Hoshino, MD, Toru Sakura, MD, Makiko Takizawa, Ph DMD, Akihiko Yokohama, MD PhD, Hiroaki Shimizu, MD PhD, Hiroshi Handa, MD PhD, Norifumi Tsukamoto, MD PhD, Hirokazu Murakami, MD PhD

Blood (2016) 128 (22): 2901.

https://doi.org/10.1182/blood.V128.22.2901.2901

Published: 2016

Journal Articles

AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma

Xiwen Gu, Carmen J. Booth, Zongzhi Liu, Matthew P. Strout

Blood (2016) 127 (1): 102–112.

https://doi.org/10.1182/blood-2015-02-628164

Published: 2016

Includes: Supplemental data

Journal Articles

ARID1A Is Recurrently and Significantly Mutated in Follicular Lymphoma (FL) and Impairs DNA Repair Efficiency

Deepak Bararia, PhD, Michael Heide, Tatiana Romashova, Pastore Alessandro, MD, Boris G. Wilson, PhD, Charles W.M. Roberts, MD PhD, Wolfgang Hiddemann, MD PhD, David M. Weinstock, MD, Oliver Weigert, MD

Blood (2014) 124 (21): 73.

https://doi.org/10.1182/blood.V124.21.73.73

Published: 2014

Journal Articles

Base Excision Repair Glycosylase Activity Is Impaired in a Subgroup of Acute Myeloid Leukemia Resulting in Increased Levels of Oxidative Base Lesions

Werner Olipitz, MD, Karin Lind, Nicole Monsberger, PhD, Anna Katschnig, MSc, Aswin Mangerich, PhD, Sybille Hofer, MSc, Eduard Schulz, MD, Franz Quehenberger, PhD, Dietmar Schlembach, MD, Christoph Robier, MD, Albert Woelfler, MD, Armin Zebisch, MD, Heinz Sill, MD

Blood (2014) 124 (21): 860.

https://doi.org/10.1182/blood.V124.21.860.860

Published: 2014

Journal Articles

The Polymorphism Of Base Excision Repair Gene, XRCC1 Arg399Gln Is Associated With The Therapy-Related Myelodysplastic Syndromes (MDS)

Batchimeg Norjmaa, Takayuki Saitoh, M.D. Ph.D., Atsushi Iwasaki, Yasuhiro Nitta, Yuta Masuda, Itsumi Suda, Ayaka Kaneko, Hiroaki Shimizu, M.D.Ph.D., Hiroshi Handa, MD, PhD, Akihiko Yokohama, MD, PhD, Norifumi Tsukamoto, MD, PhD, Toru Sakura, MD, PhD, Hirokazu Murakami, M.D.Ph.D.

Blood (2013) 122 (21): 4085.

https://doi.org/10.1182/blood.V122.21.4085.4085

Published: 2013

Journal Articles

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Subodh Kumar, PhD, Jagannath Pal, PhD, Jialan Shi, PhD, Puru Nanjappa, MS, Maria Gkotzamanidou, MD, Masood Shammas, PhD, Nikhil Munshi, MD

Blood (2013) 122 (21): 1248.

https://doi.org/10.1182/blood.V122.21.1248.1248

Published: 2013

Journal Articles

The Polymorphisms Of Base Excision Repair Genes Influence The Cytogenetic Risk Factors In Acute Myeloid Leukemia

Atsushi Iwasaki, Takayuki Saitoh, M.D. Ph.D., Yasuhiro Nitta, Batchimeg Norjimaa, Chiharu Omiya, Akira Kamiya, Nahoko Hatsumi, M.D., Hiroaki Shimizu, M.D. Ph.D., Takuma Ishizaki, M.D. Ph.D., Takumi Hoshino, Satoru Takada, MD, Hiroshi Handa, MD, PhD, Toru Sakura, MD, PhD, Akihiko Yokohama, MD, PhD, Norifumi Tsukamoto, MD, PhD, Hirokazu Murakami, M.D. Ph.D.

Blood (2013) 122 (21): 1355.

https://doi.org/10.1182/blood.V122.21.1355.1355

Published: 2013

Journal Articles

Somatic Mutations and Loss-Of-Heterozygosity Impair The DNA Repair Functions Of CUX1 in Myelodysplastic Syndromes (MDS)

Naoko Hosono, MD, PhD, Zubaidah M Ramdzan, PhD, Ranjana Pal, PhD, Hideki Makishima, MD, PhD, Bartlomiej P Przychodzen, PhD, Mikkael A. Sekeres, MD, MS, Kenichi Yoshida, MD, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Seishi Ogawa, MD, PhD, Alain Nepveu, PhD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2013) 122 (21): 1246.

https://doi.org/10.1182/blood.V122.21.1246.1246

Published: 2013

Journal Articles

The Polymorphisms of Base Excision Repair Genes Influence the Prognosis of Multiple Myeloma

Chiaki Ushie, Takayuki Saitoh, M.D. Ph.D., Atsushi Iwasaki, Norihiko Moriyama, Hikaru Hattori, Morio Matsumoto, MD, Morio Sawamura, M.D. Ph.D., Jun Isoda, M.D. Ph.D., Hiroshi Handa, M.D. Ph.D., Akihiko Yokohama, MD, PhD, Norifumi Tsukamoto, MD, PhD, Hatsue Ogawara, Ph.D., Hirokazu Murakami, M.D., Ph.D.

Blood (2012) 120 (21): 3981.

https://doi.org/10.1182/blood.V120.21.3981.3981

Published: 2012

Journal Articles

Functional Enrichment Analysis by David in Transgenic MYCN Zebrafish Model

Li-Jing Shen, Fang-Yuan Chen, Lan-Fang Cao, Yong Zhang, Hua Zhong

Blood (2012) 120 (21): 5114.

https://doi.org/10.1182/blood.V120.21.5114.5114

Published: 2012

Journal Articles

AML1/ETO Confers a Mutator Phenotype In Acute Myeloid Leukemia Associated with Downregulation of the Base-Excision-Repair Gene OGG1 ,

Victoria J Forster, Andrea Beyerle, PhD, Olaf Heidenreich, PhD, James M Allan, DPhil

Blood (2011) 118 (21): 3441.

https://doi.org/10.1182/blood.V118.21.3441.3441

Published: 2011

Journal Articles

Association Between Genetic Variants in the Base Excision Repair Pathway and Outcomes After Hematopoietic Cell Transplant.

Mukta Arora, MD, MS, Bruce Lindgren, MS, Saonli Basu, PhD, Sriharsha Nagaraj, MBBS, MS, Myron Gross, PhD, Daniel J Weisdorf, MD, Bharat Thyagarajan, MD, PhD

Blood (2009) 114 (22): 870.

https://doi.org/10.1182/blood.V114.22.870.870

Published: 2009

Journal Articles

Base Excision Repair Deficiency in Acute Myeloid Leukemia.

Werner Olipitz, Nicole Scheer, Franz Quehenberger, Karin Hiden, Julia Rankl, Dietmar Schlembach, Heinz Sill, MD

Blood (2009) 114 (22): 1106.

https://doi.org/10.1182/blood.V114.22.1106.1106

Published: 2009

Journal Articles

Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome

Diane C. Cabelof, Hiral V. Patel, Qing Chen, Holly van Remmen, Larry H. Matherly, Yubin Ge, Jeffrey W. Taub

Blood (2009) 114 (13): 2753–2763.

https://doi.org/10.1182/blood-2008-11-190330

Published: 2009

Journal Articles

Potentiation of Melphalan-Induced Cytotoxicity through Targeting of the Base Excision Repair Pathway in Multiple Myeloma.

April M. Reed, MS, Melissa L. Fishel, PhD, Mark R. Kelley, PhD, Rafat Abonour, MD

Blood (2007) 110 (11): 4799.

https://doi.org/10.1182/blood.V110.11.4799.4799

Published: 2007

Journal Articles

AML1-ETO Inhibits DNA Repair Pathways and Promotes the Accumulation of DNA Damage and the Activation of p53.

Ondrej Krejci, MD, PhD, Mark Wunderlich, Junping Wei, MD, PhD, Paul R. Andreassen, PhD, Thomas X. Lu, James C. Mulloy, PhD

Blood (2006) 108 (11): 1412.

https://doi.org/10.1182/blood.V108.11.1412.1412

Published: 2006

NARROW

Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells

Lessons from Nature: A Novel Class of TET Inhibitors for TET2 Mutant Associated Diseases

The Role and Therapeutic Target of Base Excision Repair Genes in Multiple Myeloma (MM)

Genetic Ablation or Pharmacological Inhibition of PRMT5 Affects Maintenance of Genomic Integrity in Hematopoietic Stem Cells

Base Excision Repair Gene OGG1 Affects the Relapse Risk of Acute Myeloid Leukemia

AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma

ARID1A Is Recurrently and Significantly Mutated in Follicular Lymphoma (FL) and Impairs DNA Repair Efficiency

Base Excision Repair Glycosylase Activity Is Impaired in a Subgroup of Acute Myeloid Leukemia Resulting in Increased Levels of Oxidative Base Lesions

The Polymorphism Of Base Excision Repair Gene, XRCC1 Arg399Gln Is Associated With The Therapy-Related Myelodysplastic Syndromes (MDS)

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

The Polymorphisms Of Base Excision Repair Genes Influence The Cytogenetic Risk Factors In Acute Myeloid Leukemia

Somatic Mutations and Loss-Of-Heterozygosity Impair The DNA Repair Functions Of CUX1 in Myelodysplastic Syndromes (MDS)

The Polymorphisms of Base Excision Repair Genes Influence the Prognosis of Multiple Myeloma

Functional Enrichment Analysis by David in Transgenic MYCN Zebrafish Model

AML1/ETO Confers a Mutator Phenotype In Acute Myeloid Leukemia Associated with Downregulation of the Base-Excision-Repair Gene OGG1 ,

Association Between Genetic Variants in the Base Excision Repair Pathway and Outcomes After Hematopoietic Cell Transplant.

Base Excision Repair Deficiency in Acute Myeloid Leukemia.

Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome

Potentiation of Melphalan-Induced Cytotoxicity through Targeting of the Base Excision Repair Pathway in Multiple Myeloma.

AML1-ETO Inhibits DNA Repair Pathways and Promotes the Accumulation of DNA Damage and the Activation of p53.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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