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Journal Articles

A Feasibility and Safety Study of a New CD19-Directed Fast CAR-T Therapy for Refractory and Relapsed B Cell Acute Lymphoblastic Leukemia

Junfang Yang, MD, Jiaping He, Xian Zhang, MD, Zhenguang Wang, Yongliang Zhang, Songbai Cai, Zhe Sun, Xun Ye, Yan He, Lianjun Shen, MD PhD, Jiujiang He, Gailing Zhang, MD, Dan Song, Min Zhang, Xiaona Hu, Jingjing Li, Shulian Xia, Li Xu, Wei Cao, Peihua Lu
Journal: Blood
Blood (2019) 134 (Supplement_1): 825.
https://doi.org/10.1182/blood-2019-121751
Published: 2019
Journal Articles

Phase 1 First-in-Human Trial of AMV564, a Bivalent Bispecific (2:2) CD33/CD3 T-Cell Engager, in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Peter Westervelt, MD PhD, Jorge E. Cortes, MD, Jessica K. Altman, Meixiao Long, MD, Vivian G. Oehler, MD, Ivana Gojo, MD, Jeanmarie Guenot, PhD, Patrick Chun, MD, Gail J. Roboz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 834.
https://doi.org/10.1182/blood-2019-129042
Published: 2019
Journal Articles

Preliminary Results from a Phase 1 First-in-Human Study of AMG 673, a Novel Half-Life Extended (HLE) Anti-CD33/CD3 BiTE ® (Bispecific T-Cell Engager) in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Marion Subklewe, MD, Anthony Stein, MD, Roland B. Walter, MD PhD MS, Ravi Bhatia, MD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS, David Ritchie, MD PhD, Veit Bücklein, MD, Pankit Vachhani, MD, Tian Dai, PhD, Antreas Hindoyan, PhD, Suresh Agarwal, PhD, Abraham Anderson, Sophia Khaldoyanidi, MD PhD, Farhad Ravandi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 833.
https://doi.org/10.1182/blood-2019-127977
Published: 2019
Journal Articles

An Artificial Neural Network Providing Highly Reliable Decision Support in a Routine Setting for Classification of B-Cell Neoplasms Based on Flow Cytometric Raw Data

Wolfgang Kern, MD, Franz Elsner, PhD, Max Zhao, Nanditha Mallesh, Richard Schabath, PhD, Claudia Haferlach, MD, Peter Krawitz, MD, Hannes Lueling, PhD, Torsten Haferlach, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 886.
https://doi.org/10.1182/blood-2019-130374
Published: 2019
Journal Articles

Characterization of Immune Cells Producing Regulatory Cytokines That Mediate Engraftment in Sickle Cell Disease Patients after Haploidentical Peripheral Blood Stem Cell Transplantation

Berline Francis, Arunakumar Gangaplara, PhD, Deepali K Bhat, PhD, J. Philip McCoy, PhD, Courtney D. Fitzhugh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 803.
https://doi.org/10.1182/blood-2019-130711
Published: 2019
Journal Articles

Identification of Two CAR T-Cell Populations Associated with Complete Response or Progressive Disease in Adult Lymphoma Patients Treated with Axi-Cel

Zinaida Good, PhD, Jay Y. Spiegel, MDFRCPC, Bita Sahaf, PhD, Meena B. Malipatlolla, Matthew J. Frank, MD PhD, John Baird, MD, Lori S Muffly, MD, Gursharan K. Claire, MPH, Juliana Craig, BA, Katherine A. Kong, Sean Bendall, PhD, David B Miklos, MD PhD, Crystal L. Mackall, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 779.
https://doi.org/10.1182/blood-2019-130815
Published: 2019
Journal Articles

Fas Mutations in Non-Hodgkin's Lymphoma (NHL): Implications for Disease Progression and Therapeutic Resistance

Ryan N Rys, BSc, BA, Maanasa Venkataraman, MSc, Jibin Zeng, MSc, Koren Kathleen Mann, PhD, Nathalie Johnson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1520.
https://doi.org/10.1182/blood-2019-130602
Published: 2019
Journal Articles

No Improvement in Survival for T-PLL Patients over the Last Two Decades

Matthew J Cross, MBBS, BSc, Monica Else, Ricardo Morilla, Mark Edward Ethell, MD, Michael Potter, MD, Dima El-Sharkawi, Sunil Iyengar, MBBS, FRCPath, PhD, Claire E. Dearden, MD FRCP, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 1552.
https://doi.org/10.1182/blood-2019-122094
Published: 2019
Journal Articles

Impact of Rituximab in the Clinical Outcomes of Hairy Cell Leukemia: A Retrospective Single-Institution Analysis

Kristen Gonter-Aubin, DO, Daniel Alan Kerr, MD PhD, Ashley Rose, MD, Thanh Lana Nguyen, MDBS, Julio C. Chavez, MD, Javier Pinilla Ibarz, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1542.
https://doi.org/10.1182/blood-2019-129028
Published: 2019
Journal Articles

CD4 Lymphocytes and T Regulatory Cells Show Distinct Phenotypes in Follicular Lymphoma and Classical Hodgkin Lymphoma Which May Account for Differences in Responses to Checkpoint Therapy

Sary El Daker, PhD, Qi Gao, MLS, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1513.
https://doi.org/10.1182/blood-2019-130346
Published: 2019
Journal Articles

Plasmatic Extracellular Vesicles in Acute Graft-Versus-Host Disease after Haplo-Identical Allografting with Post-Transplant Cyclophosphamide

Giuseppe Lia, PhD, Clara Di Vito, PhD, Marta Tapparo, PhD, Stefania Bruno, Elisa Zaghi, Michela Calvi, Lucia Brunello, Jacopo Mariotti, MD, Lorenzo Comba, Luisa Giaccone, Martina Fascì, Mario Boccadoro, Andrea Evangelista, MSc, Luca Castagna, MD, Giovanni Camussi, Domenico Mavilio, Benedetto Bruno, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 598.
https://doi.org/10.1182/blood-2019-126521
Published: 2019
Journal Articles

Regulation of the Elevated T Cell Glycolysis May Alleviate Acute Graft-Versus-Host Disease Post-Allotransplant

Qi Wen, MD, Song Yang, Zhong-Shi Lyu, PhD, Wei-Li Yao, Yu-Hong Chen, Ting-Ting Han, Yu Wang, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang, Yuan Kong, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 600.
https://doi.org/10.1182/blood-2019-122795
Published: 2019
Journal Articles

Exploiting an Anti-CD3/CD33 Bispecific Antibody to Redirect Donor T Cells Against HLA Loss Leukemia Relapses

Pier Edoardo Rovatti, MD, Laura Zito, MSc, Eleonora Draghi, MSc, Monika Herrmann, PhD, Anetta Marcinek, MSc, Bettina Brauchle, MSc, Cesare Covino, MSc, Mattia Di Bono, MSc, Matteo Giovanni Carrabba, MD, Massimo Bernardi, MD, Karl-Peter Hopfner, PhD, Cristina Toffalori, PhD, Fabio Ciceri, MD, Marion Subklewe, MD, Luca Vago, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 513.
https://doi.org/10.1182/blood-2019-126641
Published: 2019
Journal Articles

Single Cell Transcriptome Analysis Reveals Disease-Defining T Cell Subsets in the Tumor Microenvironment of Classic Hodgkin Lymphoma

Tomohiro Aoki, MD PhD, Lauren C. Chong, MSc, Katsuyoshi Takata, MD PhD, Katy Milne, Monirath Hav, PhD, Anthony Colombo, MS, Elizabeth Chavez, BSc, Cg RT, Tomoko Miyata-Takata, Vivian Lam, Chanel Ghesquiere, Daniel Kos, Talia Goodyear, Allen W. Zhang, Xuehai Wang, PhD, Saeed Saberi, Jiarui W. Ding, Pedro Farinha, MD PhD, Andrew P. Weng, MD PhD, Kerry J Savage, BSc, MD MSc, David W. Scott, MBChB, PhD, Gerald Krystal, PhD, Brad H. Nelson, Anja Mottok, MD PhD, Akil Merchant, MD, Sohrab P Shah, Christian Steidl, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 547.
https://doi.org/10.1182/blood-2019-121584
Published: 2019
Journal Articles

Ibrutinib Treatment in CLL Patients Improves T Cell Function and Blinatumomab Redirected Cytotoxicity

Meixiao Long, MD, Erich Williams, Clara Berard, Carolyn Cheney, BS, Eileen Hu, BS, Seema A. Bhat, MD, Kerry A. Rogers, MD, Jennifer Woyach, MD, Natarajan Muthusamy, DVM,PhD, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1049.
https://doi.org/10.1182/blood-2019-125417
Published: 2019
Journal Articles

Mesenchymal COX2-Derived PGD2 Activates an ILC2-Treg Axis to Promote Proliferation of Normal and Malignant HSPCs

Limei Wu, MD, PhD, Qiqi Lin, Zhilin Ma, Fabliha Chowdhury, Md Habibul Mazumder, Wei Du, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1208.
https://doi.org/10.1182/blood-2019-124144
Published: 2019
Journal Articles

Genomic Profiles and Subset Characterization of CD8 + terminally Differentiated Effector Memory (T EMRA ) Cells from Cancer Patients

Deok-Hwan Yang, MD PhD, Jae-Sook Ahn, Seo-Yeon Ahn, MD, Sung-Hoon Jung, MD, Je-Jung Lee, MD PhD, Hyeoung-Joon Kim, MD PhD, Young Rok Do, PhDMD, Sang Yun Song, MD PhD, Ga-Young Song, Hyeong Jong Kim, MD, Theresa Kim
Journal: Blood
Blood (2019) 134 (Supplement_1): 2329.
https://doi.org/10.1182/blood-2019-126533
Published: 2019
Journal Articles

Single Cell Signaling Responses Stratify Immune and Leukemia Cell Populations in Acute Myeloid Leukemia

Kathryn I Sunthankar, MD, Benjamin J Reisman, BS, Candace H Cote, BS, Paul Brent Ferrell, Jr., MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2680.
https://doi.org/10.1182/blood-2019-129602
Published: 2019
Journal Articles

T Cells Educated By DC/AML Fusions in the Context of 4-1BB Costimulation As a Potent Strategy for Adoptive Cellular Therapy

Jessica Liegel, MD, Dina Stroopinsky, PhD, Haider Ghiasuddin, Adam Morin, Marzia Capelletti, PhD MMSc, Shira Orr, PhD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, David E. Avigan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2673.
https://doi.org/10.1182/blood-2019-131491
Published: 2019
Journal Articles

Altered Immunophenotypes on Leukemic and/or Monocytic Cells from Acute Myeloid Leukemia Highly Predict for Nucleophosmin Gene Mutation

Sergio Matarraz, Pilar Leoz, Xavier Calvo, MD PhD, Luis García Alonso, Rosa Ayala Bueno, José Ignacio Sánchez-Gallego, PhD, Neus Villamor, Enrique Colado, MD PhD, María Belén Vidriales, María Isabel Prieto Conde, Maria Carmen Chillon, Ramón García-Sanz, MD PhD, Vincent H.J. Van Der Velden, PhD, Félix López Cadenas, MD, María Díez-Campelo, MD PhD, Leonor Arenillas, MD PhD, Sara Alonso, MD, Ariana Fonseca, Covadonga Quirós Caso, Laura Magnano, José Antonio Garcia Vela, MD, Carlos Fernandez, Daniela Damasceno, Andrea Mayado, Susana Barrena, PhD, Alberto Orfao, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2687.
https://doi.org/10.1182/blood-2019-131733
Published: 2019