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Journal Articles

Very long chain fatty acid metabolism is required in acute myeloid leukemia

Matthew Tcheng, Alessia Roma, Nawaz Ahmed, Richard W. Smith, Preethi Jayanth, Mark D. Minden, Aaron D. Schimmer, David A. Hess, Kristin Hope, Kevin A. Rea, Tariq A. Akhtar, Eric Bohrnsen, Angelo D’Alessandro, Al-Walid Mohsen, Jerry Vockley, Paul A. Spagnuolo

Blood (2021) 137 (25): 3518–3532.

https://doi.org/10.1182/blood.2020008551

Published: 2021

Includes: Supplemental data

Journal Articles

Break the lifeline of AML cells

Yoko Tabe, Marina Konopleva

Blood (2021) 137 (25): 3465–3467.

https://doi.org/10.1182/blood.2021011475

Published: 2021

Journal Articles

Identification of GPAT1 As a Novel Therapeutic Target for Acute Leukemia By Inhibiting Leukemia Specific Metabolism

Hidetoshi Irifune, MD, Yu Kochi, MD, Masayasu Hayashi, MD PhD, Yoshikane Kikushige, MD PhD, Toshihiro Miyamoto, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 1384.

https://doi.org/10.1182/blood-2019-125661

Published: 2019

Journal Articles

Inhibiting Very Long Chain Acyl-CoA Dehydrogenase (VLCAD) Induces Selective Leukemia Cell Death

Matthew Tcheng, BSc, Alessia Roma, BSc, Nawaz Ahmed, MSc, Richard Smith, PhD, Preethi Jayanth, PhD, Mark D. Minden, MD PhD, Rose Hurren, BSc, Aaron D Schimmer, MD PhD, Gale Bozzo, PhD, David Hess, PhD, Kristin Hope, PhD, Kevin Rea, MSc, Tariq A. Akhtar, PhD, Al-Walid Mohsen, PhD, Jerry Vockley, MD PhD, Paul A. Spagnuolo, PhD

Blood (2019) 134 (Supplement_1): 3922.

https://doi.org/10.1182/blood-2019-122262

Published: 2019

Journal Articles

A Novel Metabolic Transcriptome Identified in Myelodysplastic Syndromes (MDS) Correlates with OMS Classification and Poor Prognosis

Christophe Desterke, Estelle Balducci, Xavier Fund, Claire Borie, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2018) 132 (Supplement 1): 5495.

https://doi.org/10.1182/blood-2018-99-110678

Published: 2018

Journal Articles

Alloantigen-Activated Human T-Cells Increase Extracellular Fatty Acid Uptake and Intracellular Lipid Metabolism during Xenogeneic Gvhd

Hirofumi Nakano, MD, Kazuya Sato, MD PhD, Hiroko Hayakawa, PhD, Kiyomi Mashima, MD, Daisuke Minakata, MD, Kaoru Morita, MD PhD, Ryoko Yamasaki, MD, Masahiro Ashizawa, MD, Chihiro Yamamoto, MD PhD, Kaoru Hatano, MD PhD, Shin-ichiro Fujiwara, MD PhD, Iekuni Oh, MD PhD, Ken Ohmine, MD PhD, Kazuo Muroi, MD PhD, Yoshinobu Kanda, MD PhD

Blood (2018) 132 (Supplement 1): 3320.

https://doi.org/10.1182/blood-2018-99-110011

Published: 2018

Journal Articles

Aspariginase-Triggered Hyperglycerimedia: An Analysis on Germline Regulatory Gene Variations in Adult Acute Lymphoblastic Leukemia Patients

Sari Kytölä, MD, Suvi Rantamo, MSc, Matti Jauhiainen, PhD, Kimmo Porkka, MD PhD, Outi Kilpivaara, PhD, Ulla Wartiovaara-Kautto, MD PhD

Blood (2017) 130 (Supplement 1): 1287.

https://doi.org/10.1182/blood.V130.Suppl_1.1287.1287

Published: 2017

Journal Articles

CML Patients with Primary Resistance or Suboptimal Response to TKI Therapy Have Variants in Genes Affecting Drug Absorption and Metabolism

Paavo Pietarinen, MSc, Perttu Koskenvesa, MD, Judith Klievink, Kimmo Porkka, MD PhD, Mikko Niemi, MD PhD, Satu Mustjoki, MD PhD

Blood (2016) 128 (22): 3071.

https://doi.org/10.1182/blood.V128.22.3071.3071

Published: 2016

Journal Articles

The Trans-Fatty Acid, Elaidic Acid, Inhibits Macrophage Fatty Acid Catabolism and Stimulates Expression of Inflammatory Mediators

Lisa J Robinson, Janelle Zacherl, Harry C Blair, Stephanie J Mihalik

Blood (2012) 120 (21): 3277.

https://doi.org/10.1182/blood.V120.21.3277.3277

Published: 2012

Journal Articles

Lysophospholipid Acylation in RBC.

Eric Soupene, PhD, Frans A. Kuypers, PhD

Blood (2006) 108 (11): 1575.

https://doi.org/10.1182/blood.V108.11.1575.1575

Published: 2006

Journal Articles

Acyl-CoA Turnover in RBC.

Eric Soupene, PhD, Melvin Siliakus, Frans A. Kuypers, PhD

Blood (2006) 108 (11): 1579.

https://doi.org/10.1182/blood.V108.11.1579.1579

Published: 2006

Journal Articles

Multiple Erythroid Isoforms of Human Long-Chain acyl-CoA Synthetases Are Produced by a Switch of the Fatty Acid Gate-Domains.

Eric Soupene, PhD, Frans A. Kuypers, PhD

Blood (2005) 106 (11): 1672.

https://doi.org/10.1182/blood.V106.11.1672.1672

Published: 2005

NARROW

Very long chain fatty acid metabolism is required in acute myeloid leukemia

Break the lifeline of AML cells

Identification of GPAT1 As a Novel Therapeutic Target for Acute Leukemia By Inhibiting Leukemia Specific Metabolism

Inhibiting Very Long Chain Acyl-CoA Dehydrogenase (VLCAD) Induces Selective Leukemia Cell Death

A Novel Metabolic Transcriptome Identified in Myelodysplastic Syndromes (MDS) Correlates with OMS Classification and Poor Prognosis

Alloantigen-Activated Human T-Cells Increase Extracellular Fatty Acid Uptake and Intracellular Lipid Metabolism during Xenogeneic Gvhd

Aspariginase-Triggered Hyperglycerimedia: An Analysis on Germline Regulatory Gene Variations in Adult Acute Lymphoblastic Leukemia Patients

CML Patients with Primary Resistance or Suboptimal Response to TKI Therapy Have Variants in Genes Affecting Drug Absorption and Metabolism

The Trans-Fatty Acid, Elaidic Acid, Inhibits Macrophage Fatty Acid Catabolism and Stimulates Expression of Inflammatory Mediators

Lysophospholipid Acylation in RBC.

Acyl-CoA Turnover in RBC.

Multiple Erythroid Isoforms of Human Long-Chain acyl-CoA Synthetases Are Produced by a Switch of the Fatty Acid Gate-Domains.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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