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Yonghua Ling
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Journal Articles

OSU-T315: a novel targeted therapeutic that antagonizes AKT membrane localization and activation of chronic lymphocytic leukemia cells

Ta-Ming Liu, Yonghua Ling, Jennifer A. Woyach, Kyle Beckwith, Yuh-Ying Yeh, Erin Hertlein, Xiaoli Zhang, Amy Lehman, Farrukh Awan, Jeffrey A. Jones, Leslie A. Andritsos, Kami Maddocks, Jessica MacMurray, Santosh B. Salunke, Ching-Shih Chen, Mitch A. Phelps, John C. Byrd, Amy J. Johnson
Journal: Blood
Blood (2015) 125 (2): 284–295.
https://doi.org/10.1182/blood-2014-06-583518
Published: 2015
Includes: Supplemental data
Journal Articles

A Dose Escalation Study of Ibrutinib with Lenalidomide for Relapsed and Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Daniel A. Pollyea, MD MS, Steven Coutre, MD, Lia Gore, Nichole Adler, RN, BSN, Pamela Harris, MD, Mitch A. Phelps, PhD, Amy J. Johnson, PhD, YongHua Ling, Hao Li, Jonathan A Gutman, MD, John C. Byrd, MD
Journal: Blood
Blood (2014) 124 (21): 1987.
https://doi.org/10.1182/blood.V124.21.1987.1987
Published: 2014
Journal Articles

OSU-T315, An Integrin-Linked Kinase (ILK) Inhibitor, Induces Apoptosis By Targeting B Cell Receptor and CD49d Mediated AKT/ERK Activation In Chronic Lymphocytic Leukemia Cells

Ta-Ming Liu, YongHua Ling, Mitch A. Phelps, PhD, Jennifer A. Woyach, MD, Erin K Hertlein, PhD, William H. Towns, Jessica MacMurray, Santosh B. Salunke, PhD, Ching-Shih Chen, PhD, John C. Byrd, MD, Amy J. Johnson, PhD
Journal: Blood
Blood (2013) 122 (21): 2523.
https://doi.org/10.1182/blood.V122.21.2523.2523
Published: 2013
Journal Articles

Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine

Donald Lavelle, Kestis Vaitkus, Yonghua Ling, Maria A. Ruiz, Reda Mahfouz, Kwok Peng Ng, Soledad Negrotto, Nicola Smith, Pramod Terse, Kory J. Engelke, Joseph Covey, Kenneth K. Chan, Joseph DeSimone, Yogen Saunthararajah
Journal: Blood
Blood (2012) 119 (5): 1240–1247.
https://doi.org/10.1182/blood-2011-08-371690
Published: 2012
Includes: Supplemental data
Journal Articles

Tetrahydrouridine Co-Administration Improves Oral Bioavailability and Dampens Inter-Individual Variability of Decitabine Pharmacokinetics In Baboons

Donald Lavelle, Ph.D., Kestis Vaitkus, YongHua Ling, Nicola Smith, Kenneth K. Chan, PhD, Joseph DeSimone, PhD, Yogenthiran Saunthararajah, MD
Journal: Blood
Blood (2010) 116 (21): 2081.
https://doi.org/10.1182/blood.V116.21.2081.2081
Published: 2010