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Maria A. Ruiz
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Journal Articles

Phase 1 Evaluation of Oral Tetrahydrouridine-Decitabine As Non-Cytotoxic Epigenetic Disease Modification for Sickle Cell Disease

Robert E Molokie, MD, Donald Lavelle, PhD, Michel Gowhari, DO, Michael Pacini, PharmD, Lani Krauz, Johara Hassan, MD, Vinzon Ibanez, Maria A Ruiz, Daisy Pacelli, Sherry Fada, Mitch A. Phelps, PhD, Santosh L. Saraf, MD, Lewis L. Hsu, MD PhD, Victor R. Gordeuk, MD, Joseph DeSimone, PhD, Yogenthiran Saunthararajah, MD
Journal: Blood
Blood (2016) 128 (22): 124.
https://doi.org/10.1182/blood.V128.22.124.124
Published: 2016
Journal Articles

Mitophagy Induction Is a Potential Therapeutic Approach for Sickle Cell Disease

Ramasamy Jagadeeswaran, PhD, Benjamin Alejandro Vazquez, BS, Vinzon Ibanez, Maria A Ruiz, Robert E Molokie, MD, Joseph DeSimone, PhD, Donald Lavelle, PhD, Angela Rivers, MD PhD
Journal: Blood
Blood (2016) 128 (22): 267.
https://doi.org/10.1182/blood.V128.22.267.267
Published: 2016
Journal Articles

Combination with Thu to Address Pharmacologic Limitations of Decitabine, Interim PK/PD from a Phase 1/2 Clinical Trial of Oral Thu-Decitabine in Sickle Cell Disease

Donald Lavelle, PhD, Michel Gowhari, DO, Michael Pacini, PharmD, Lani Krauz, RN, Johara Hassan, MD, Vinzon Ibanez, Maria A. Ruiz, MSc, Daisy Pacelli, BSc, Chaher Alhandalous, MD, Mitch A. Phelps, PhD, Kathleen Fenner, BS,MS, Reda Z. Mahfouz, MDPhD, John Barnard, Lewis L. Hsu, MD PhD, Victor R. Gordeuk, MD, Joseph DeSimone, PhD, Yogen Saunthararajah, MD, Robert E. Molokie, MD
Journal: Blood
Blood (2014) 124 (21): 90.
https://doi.org/10.1182/blood.V124.21.90.90
Published: 2014
Journal Articles

Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine

Donald Lavelle, Kestis Vaitkus, Yonghua Ling, Maria A. Ruiz, Reda Mahfouz, Kwok Peng Ng, Soledad Negrotto, Nicola Smith, Pramod Terse, Kory J. Engelke, Joseph Covey, Kenneth K. Chan, Joseph DeSimone, Yogen Saunthararajah
Journal: Blood
Blood (2012) 119 (5): 1240–1247.
https://doi.org/10.1182/blood-2011-08-371690
Published: 2012
Includes: Supplemental data
Journal Articles

Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma

Brief Report
Jose A. Martinez-Climent, Esperanza Vizcarra, Dolors Sanchez, David Blesa, Isabel Marugan, Isabel Benet, Françesc Sole, Francisca Rubio-Moscardo, Maria J. Terol, Joan Climent, Elena Sarsotti, Mar Tormo, Enrique Andreu, Marta Salido, Maria A. Ruiz, Felipe Prosper, Reiner Siebert, Martin J. S. Dyer, Javier Garcı́a-Conde
Journal: Blood
Blood (2001) 98 (12): 3479–3482.
https://doi.org/10.1182/blood.V98.12.3479
Published: 2001