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Soledad Negrotto
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Journal Articles

Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine

Donald Lavelle, Kestis Vaitkus, Yonghua Ling, Maria A. Ruiz, Reda Mahfouz, Kwok Peng Ng, Soledad Negrotto, Nicola Smith, Pramod Terse, Kory J. Engelke, Joseph Covey, Kenneth K. Chan, Joseph DeSimone, Yogen Saunthararajah
Journal: Blood
Blood (2012) 119 (5): 1240–1247.
https://doi.org/10.1182/blood-2011-08-371690
Published: 2012
Includes: Supplemental data
Journal Articles

Effective and Non-Cytotoxic p53 Independent Epigenetic-Differentiation Therapy In Xeno-Transplant Models of Human Acute Myeloid Leukemia

Kwok Peng Ng, PhD, Quteba Ebrahem, MD, Soledad Negrotto, PhD, Reda Mahfouz, MD, Kevin Link, PhD, Zhenbo Hu, MD, Xiaorong Gu, PhD, Anjali Advani, MD, Matt Kalaycio, MD, Mikkael A. Sekeres, MD, MS, Edward A. Copelan, MD, Jaroslaw P Maciejewski, MD, PhD, FACP, James C. Mulloy, PhD, Yogenthiran Saunthararajah, MD
Journal: Blood
Blood (2010) 116 (21): 3309.
https://doi.org/10.1182/blood.V116.21.3309.3309
Published: 2010
Journal Articles

Non-p53 Dependent, Leukemia Initiating-Cell Selective, Therapy.

Kwok Peng Ng, Soledad Negrotto, Zhenbo Hu, Kevin A Link, Santosh L Saraf, MD, Anjali Advani, M.D., Mikkael A. Sekeres, MD, MS, Jaroslaw P. Maciejewski, MD, PhD, James C. Mulloy, PhD, Yogenthiran Saunthararajah, M.D.
Journal: Blood
Blood (2009) 114 (22): 2077.
https://doi.org/10.1182/blood.V114.22.2077.2077
Published: 2009
Journal Articles

Runx1 Deficiency Produces Aberrant Progenitor Self-Renewal through Selective Compromise of Pu.1 Mediated Transactivation but Not Transrepression.

Zhenbo Hu, Soledad Negrotto, Kristine Marie Baraoidan, Vinzon Ibanez, Aron Shama, Fariborz Mortazavi, Steven Ackerman, Shrihari Kadkol, Giuseppina Nucifora, Yogen Saunthararajah
Journal: Blood
Blood (2008) 112 (11): 1351.
https://doi.org/10.1182/blood.V112.11.1351.1351
Published: 2008
Journal Articles

Differentiation-Chronology Specific Function of DNMT1 and Selective Anti-Leukemia Stem-Cell Therapy

Soledad Negrotto, Zhenbo Hu, Kevin A Link, Hien Duong, Andrew E. Schade, MD, PhD, Jaroslaw P. Maciejewski, MD, PhD, James C. Mulloy, PhD, Yogenthiran Saunthararajah
Journal: Blood
Blood (2008) 112 (11): 201.
https://doi.org/10.1182/blood.V112.11.201.201
Published: 2008
Journal Articles

Differences Between Normal and Leukemic Stem Cell-Specific Methylome Indicates Aberrantly Silenced Genes Involved in the Pathogenesis of Malignant Evolution

Rebecca D Ganetzky, B.A., Ying Jiang, M.D., Ph.D., Jeffrey Falk, Ph.D., Mingjie Jin, Ph.D., Dongyan Liu, M.S., Soledad Negrotto, Ph.D., Yogen Saunthararajah, M.D., Jaroslaw P. Maciejewski, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 599.
https://doi.org/10.1182/blood.V112.11.599.599
Published: 2008