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Journal Articles

Molecular and Cytokine Correlates of Anemia Response to Treatment with DISC-0974 (An Anti-Hemojuvelin Antibody) in Non-Transfusion-Dependent Patients with Myelofibrosis

Ayalew Tefferi, Chandra Hutchens, Antoine N. Saliba, Giuseppe Gaetano Loscocco, Kebede Begna, William J. Hogan, Kaaren K. Reichard, Animesh D. Pardanani, Sima Bhatt, William Savage, Naseema Gangat

Blood (2024) 144 (Supplement 1): 6678.

https://doi.org/10.1182/blood-2024-209070

Published: 2024

Journal Articles

The EPP LIGHT Study: A Survey Describing the Burden of Erythropoietic Protoporphyria and X-Linked Protoporphyria

Hetanshi Naik, Manisha Balwani, Hilary H Colwell, Susan D Mathias, Kristen Wheeden, Chelsea Norregaard, Melanie Chin, William Savage

Blood (2024) 144 (Supplement 1): 3631.

https://doi.org/10.1182/blood-2024-202105

Published: 2024

Journal Articles

Application of a Validated Method for Quantifying Circulating Protoporphyrin IX to the Beacon Trial of Bitopertin in Erythropoietic Protoporphyria

Heidi Mangus, George Mensing, William Savage, Melanie Chin, Yue Chen, Guowen Liu, Hua Yang

Blood (2023) 142 (Supplement 1): 5228.

https://doi.org/10.1182/blood-2023-178122

Published: 2023

Journal Articles

A Phase 1b Trial of DISC-0974, an Anti-Hemojuvelin Antibody, in Patients with Myelofibrosis and Anemia

Naseema Gangat, James M. Foran, Anna B. Halpern, Raajit K. Rampal, Natasha Novikov, Akshay Buch, Olivia Pelletier, William Savage, Ayalew Tefferi

Blood (2023) 142 (Supplement 1): 4564.

https://doi.org/10.1182/blood-2023-174922

Published: 2023

Journal Articles

A Phase 1b Double-Blind, Placebo-Controlled Study of DISC-0974, an Anti-Hemojuvelin Antibody, in Patients with Non-Dialysis Dependent Chronic Kidney Disease and Anemia

Samir Arora, Jorge Monroy, Pablo Pergola, Arnold Silva, Akshay Buch, Natasha Novikov, Olivia Pelletier, William Savage

Blood (2023) 142 (Supplement 1): 5236.

https://doi.org/10.1182/blood-2023-178033

Published: 2023

Journal Articles

Anti-Hemojuvelin Monoclonal Antibody DISC-0974 Elicits a Durable and Consistent Response with Repeated Dosing in Cynomolgus Monkeys

Scott A Reisman, William Savage, Guowen Liu, Hua Yang

Blood (2023) 142 (Supplement 1): 5224.

https://doi.org/10.1182/blood-2023-179470

Published: 2023

Journal Articles

Interim Analyses from the Beacon Trial: A Phase 2, Randomized, Open-Label Trial of Bitopertin in Erythropoietic Protoporphyria

Gayle Ross, Peter Stewart, George Mensing, Melanie Chin, Haley Howell, Heidi Mangus, William Savage

Blood (2023) 142 (Supplement 1): 923.

https://doi.org/10.1182/blood-2023-175011

Published: 2023

Journal Articles

A Phase I/II, Intra-Patient Dose-Escalation Study of Bitopertin, a Selective Inhibitor of GlyT1 and Heme Synthesis, for Steroid-Refractory Diamond-Blackfan Anemia

David J. Young, Tania Rene Machado, Raymond T. Doty, Colin O. Wu, Janis L. Abkowitz, William Savage, Cynthia E. Dunbar

Blood (2023) 142 (Supplement 1): 1086.

https://doi.org/10.1182/blood-2023-173821

Published: 2023

Journal Articles

Rurioctocog alfa pegol PK-guided prophylaxis in hemophilia A: results from the phase 3 PROPEL study

Robert Klamroth, Jerzy Windyga, Vlad Radulescu, Peter W. Collins, Oleksandra Stasyshyn, Hishamshah Mohd Ibrahim, Werner Engl, Srilatha D. Tangada, William Savage, Bruce Ewenstein

Blood (2021) 137 (13): 1818–1827.

https://doi.org/10.1182/blood.2020005673

Published: 2021

Includes: Supplemental data

Journal Articles

Platelet Proteins Cause Allergic Transfusion Reactions through an Immunoglobulin-Dependent Mechanism

Dong-Young Donna Lee, Igla Muskaj, William Savage, MD PhD

Blood (2016) 128 (22): 91.

https://doi.org/10.1182/blood.V128.22.91.91

Published: 2016

Journal Articles

Developing an in Vitro Functional Model of Allergic Transfusion Reactions

William Savage, MD, PhD, Aaron A. R. Tobian, MD, PhD, Jessica Savage, MD MHS, Chris Thoburn, Paul M. Ness, MD, John T. Schroeder, PhD

Blood (2012) 120 (21): 3426.

https://doi.org/10.1182/blood.V120.21.3426.3426

Published: 2012

Journal Articles

Bleeding risks are higher in children versus adults given prophylactic platelet transfusions for treatment-induced hypoproliferative thrombocytopenia

Cassandra D. Josephson, Suzanne Granger, Susan F. Assmann, Marta-Inés Castillejo, Ronald G. Strauss, Sherrill J. Slichter, Marie E. Steiner, Janna M. Journeycake, Courtney D. Thornburg, James Bussel, Eric F. Grabowski, Ellis J. Neufeld, William Savage, Steven R. Sloan

Blood (2012) 120 (4): 748–760.

https://doi.org/10.1182/blood-2011-11-389569

Published: 2012

Includes: Supplemental data

Journal Articles

Longitudinal Analysis of Serial Liver Biopsies in Chronically Transfused Sickle Cell Disease

Jaime L Wolfe, MD, Robert Anders, MD, PhD, Shirley Reddoch, MD, Kathleen Schwarz, MD, William Savage, MD

Blood (2011) 118 (21): 1052.

https://doi.org/10.1182/blood.V118.21.1052.1052

Published: 2011

Journal Articles

Identification of Thrombospondin-1 and L-Selectin as Potential Plasma Biomarkers of Silent Cerebral Infarct In Children with Sickle Cell Disease Using a Proteomic-Based Approach

Lisa M. Williams, MD, Zongming Fu, PhD, Pratima Dulloor, Kun Yan, PhD, John J. Strouse, MD, PhD, William Savage, MD, Emily Barron-Casella, PhD, Michael R. DeBaun, MD, MPH, Jennifer E. Van Eyk, PhD, Allen Everett, MD, James F. Casella, MD

Blood (2010) 116 (21): 259.

https://doi.org/10.1182/blood.V116.21.259.259

Published: 2010

Journal Articles

Natural History of Paroxysmal Nocturnal Hemoglobinuria Clones In Patients Presenting as Aplastic Anemia

Jeffrey J Pu, MD, Ph.D., Galina Mukhina, MD, Ph.D., Hao Wang, Ph.D., William Savage, MD, Robert A Brodsky, MD

Blood (2010) 116 (21): 4428.

https://doi.org/10.1182/blood.V116.21.4428.4428

Published: 2010

Journal Articles

Multicenter survey on the outcome of transplantation of hematopoietic cells in patients with the complete form of DiGeorge anomaly

Ales Janda, Petr Sedlacek, Manfred Hönig, Wilhelm Friedrich, Martin Champagne, Tadashi Matsumoto, Alain Fischer, Benedicte Neven, Audrey Contet, Danielle Bensoussan, Pierre Bordigoni, David Loeb, William Savage, Nada Jabado, Francisco A. Bonilla, Mary A. Slatter, E. Graham Davies, Andrew R. Gennery

Blood (2010) 116 (13): 2229–2236.

https://doi.org/10.1182/blood-2010-03-275966

Published: 2010

Includes: Supplemental data

NARROW

Molecular and Cytokine Correlates of Anemia Response to Treatment with DISC-0974 (An Anti-Hemojuvelin Antibody) in Non-Transfusion-Dependent Patients with Myelofibrosis

The EPP LIGHT Study: A Survey Describing the Burden of Erythropoietic Protoporphyria and X-Linked Protoporphyria

Application of a Validated Method for Quantifying Circulating Protoporphyrin IX to the Beacon Trial of Bitopertin in Erythropoietic Protoporphyria

A Phase 1b Trial of DISC-0974, an Anti-Hemojuvelin Antibody, in Patients with Myelofibrosis and Anemia

A Phase 1b Double-Blind, Placebo-Controlled Study of DISC-0974, an Anti-Hemojuvelin Antibody, in Patients with Non-Dialysis Dependent Chronic Kidney Disease and Anemia

Anti-Hemojuvelin Monoclonal Antibody DISC-0974 Elicits a Durable and Consistent Response with Repeated Dosing in Cynomolgus Monkeys

Interim Analyses from the Beacon Trial: A Phase 2, Randomized, Open-Label Trial of Bitopertin in Erythropoietic Protoporphyria

A Phase I/II, Intra-Patient Dose-Escalation Study of Bitopertin, a Selective Inhibitor of GlyT1 and Heme Synthesis, for Steroid-Refractory Diamond-Blackfan Anemia

Rurioctocog alfa pegol PK-guided prophylaxis in hemophilia A: results from the phase 3 PROPEL study

Platelet Proteins Cause Allergic Transfusion Reactions through an Immunoglobulin-Dependent Mechanism

Developing an in Vitro Functional Model of Allergic Transfusion Reactions

Bleeding risks are higher in children versus adults given prophylactic platelet transfusions for treatment-induced hypoproliferative thrombocytopenia

Longitudinal Analysis of Serial Liver Biopsies in Chronically Transfused Sickle Cell Disease

Identification of Thrombospondin-1 and L-Selectin as Potential Plasma Biomarkers of Silent Cerebral Infarct In Children with Sickle Cell Disease Using a Proteomic-Based Approach

Natural History of Paroxysmal Nocturnal Hemoglobinuria Clones In Patients Presenting as Aplastic Anemia

Multicenter survey on the outcome of transplantation of hematopoietic cells in patients with the complete form of DiGeorge anomaly

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American Society of Hematology

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American Society of Hematology

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