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Journal Articles

Rare germline complement factor H variants in patients with paroxysmal nocturnal hemoglobinuria

Pedro Henrique Prata, Jacques-Emmanuel Galimard, Flore Sicre de Fontbrune, Anna Duval, Paula Vieira Martins, Stephane Roncelin, Pierre-Édouard Debureaux, Anne-Claire Lepretre, Lise Larcher, Rudy Birsen, Ygal Benhamou, Jean Soulier, Gérard Socié, Véronique Fremeaux-Bacchi, Régis Peffault de Latour

Blood (2023) 141 (15): 1812–1816.

https://doi.org/10.1182/blood.2022017019

Published: 2023

Includes: Supplemental data

Journal Articles

How I diagnose and treat atypical hemolytic uremic syndrome

Fadi Fakhouri, Nora Schwotzer, Véronique Frémeaux-Bacchi

Blood (2023) 141 (9): 984–995.

https://doi.org/10.1182/blood.2022017860

Published: 2023

Includes: Supplemental data

Journal Articles

Characterization of Patients with aHUS and Triggering/Associated Events, with and without Complement Pathogenic Variants or Anti-Cfh Antibodies: A Global aHUS Registry Analysis

Andrew Siedlecki, Imad Al-Dakkak, Katerina Anokhina, Nicole Isbel, Véronique Frémeaux-Bacchi, Rodney Gilbert, Laurence Greenbaum, Gema Ariceta, Gianluigi Ardissino, Franz Schaefer, Eric Rondeau, Christoph Licht

Blood (2022) 140 (Supplement 1): 2767–2769.

https://doi.org/10.1182/blood-2022-155814

Published: 2022

Journal Articles

COVID-19 as a potential trigger of complement-mediated atypical HUS

Carine El Sissy, Antonin Saldman, Gilbert Zanetta, Paula Vieira Martins, Coralie Poulain, Raphaël Cauchois, Gilles Kaplanski, Jean-Pierre Venetz, Mickaël Bobot, Hélène Dobosziewicz, Laurent Daniel, Marie Koubi, Salima Sadallah, Samuel Rotman, Christiane Mousson, Manuel Pascual, Véronique Frémeaux-Bacchi, Fadi Fakhouri

Blood (2021) 138 (18): 1777–1782.

https://doi.org/10.1182/blood.2021012752

Published: 2021

Includes: Supplemental data

Journal Articles

Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study

Blood (2021) 137 (18): 2438–2449.

https://doi.org/10.1182/blood.2020009280

Published: 2021

Includes: Supplemental data

Journal Articles

Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group

Blood (2020) 136 (19): 2103–2117.

https://doi.org/10.1182/blood.2020005221

Published: 2020

Includes: Supplemental data

Journal Articles

Treatment of Delayed Hemolytic Transfusion Reactions in Sickle Cell Disease Patients By an Anti-C5 Antibody

Blood (2019) 134 (Supplement_1): 2458.

https://doi.org/10.1182/blood-2019-127176

Published: 2019

Journal Articles

Treatment of B-cell disorder improves renal outcome of patients with monoclonal gammopathy–associated C3 glomerulopathy

Sophie Chauvet, Véronique Frémeaux-Bacchi, Florent Petitprez, Alexandre Karras, Laurent Daniel, Stéphane Burtey, Gabriel Choukroun, Yahsou Delmas, Dominique Guerrot, Arnaud François, Moglie Le Quintrec, Vincent Javaugue, David Ribes, Laurence Vrigneaud, Bertrand Arnulf, Jean Michel Goujon, Pierre Ronco, Guy Touchard, Frank Bridoux

Blood (2017) 129 (11): 1437–1447.

https://doi.org/10.1182/blood-2016-08-737163

Published: 2017

Includes: Supplemental data

Journal Articles

Eculizumab salvage therapy for delayed hemolysis transfusion reaction in sickle cell disease patients

Guillaume Dumas, Anoosha Habibi, Thierry Onimus, Jean-Claude Merle, Keyvan Razazi, Armand Mekontso Dessap, Frederic Galactéros, Marc Michel, Veronique Frémeaux Bacchi, France Noizat Pirenne, Pablo Bartolucci

Blood (2016) 127 (8): 1062–1064.

https://doi.org/10.1182/blood-2015-09-669770

Published: 2016

Journal Articles

The Global aHUS Registry: Characteristics of 826 Patients with Atypical Hemolytic Uremic Syndrome

Christoph Licht, MD FRCP(C), FASN, Gianluigi Ardissino, MD PhD, Gema Ariceta, MD PhD, David J. Cohen, MD, Christoph Gasteyger, MD, Laurence A. Greenbaum, MDPhD, Masayo Ogawa, MD FAAP, Varant Kupelian, PhD, Franz Schaefer, MD, Johan Vande Walle, MD PhD, Véronique Frémeaux-Bacchi, MD PhD

Blood (2015) 126 (23): 4640.

https://doi.org/10.1182/blood.V126.23.4640.4640

Published: 2015

Journal Articles

Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome

Elizabeth C. Schramm, Lubka T. Roumenina, Tania Rybkine, Sophie Chauvet, Paula Vieira-Martins, Christophe Hue, Tara Maga, Elisabetta Valoti, Valerie Wilson, Sakari Jokiranta, Richard J. H. Smith, Marina Noris, Tim Goodship, John P. Atkinson, Veronique Fremeaux-Bacchi

Blood (2015) 125 (15): 2359–2369.

https://doi.org/10.1182/blood-2014-10-609073

Published: 2015

Includes: Supplemental data

Journal Articles

Loss of DGKε induces endothelial cell activation and death independently of complement activation

Sarah Bruneau, Mélanie Néel, Lubka T. Roumenina, Marie Frimat, Lætitia Laurent, Véronique Frémeaux-Bacchi, Fadi Fakhouri

Blood (2015) 125 (6): 1038–1046.

https://doi.org/10.1182/blood-2014-06-579953

Published: 2015

Includes: Supplemental data

Journal Articles

Assessing complement blockade in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab

Régis Peffault de Latour, Véronique Fremeaux-Bacchi, Raphaël Porcher, Aliénor Xhaard, Jérémie Rosain, Diana Cadena Castaneda, Paula Vieira-Martins, Stéphane Roncelin, Paula Rodriguez-Otero, Aurélie Plessier, Flore Sicre de Fontbrune, Sarah Abbes, Marie Robin, Gérard Socié

Blood (2015) 125 (5): 775–783.

https://doi.org/10.1182/blood-2014-03-560540

Published: 2015

Includes: Supplemental data

Journal Articles

Baseline Demographics and Characteristics of 466 Patients with Atypical Hemolytic Uremic Syndrome in the Global aHUS Registry

Christoph Licht, MD FRCP(C), FASN, Gianluigi Ardissino, MD PhD, Gema Ariceta, MD PhD, David Cohen, MD, Christoph Gasteyger, MD, Laurence A. Greenbaum, MDPhD, Masayo Ogawa, MD FAAP, Franz Schaefer, MD, Johan Vande Walle, MD PhD, Veronique Fremeaux-Bacchi, MD PhD

Blood (2014) 124 (21): 4204.

https://doi.org/10.1182/blood.V124.21.4204.4204

Published: 2014

Journal Articles

The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status

Julie Rayes, Lubka T. Roumenina, Jordan D. Dimitrov, Yohann Repessé, Mathieu Ing, Olivier Christophe, T. Sakari Jokiranta, Lise Halbwachs-Mecarelli, Annie Borel-Derlon, Srinivas V. Kaveri, Véronique Frémeaux-Bacchi, Sébastien Lacroix-Desmazes

Blood (2014) 123 (1): 121–125.

https://doi.org/10.1182/blood-2013-04-495853

Published: 2014

Includes: Supplemental data

Journal Articles

Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome

Marie Frimat, Fanny Tabarin, Jordan D. Dimitrov, Caroline Poitou, Lise Halbwachs-Mecarelli, Veronique Fremeaux-Bacchi, Lubka T. Roumenina

Blood (2013) 122 (2): 282–292.

https://doi.org/10.1182/blood-2013-03-489245

Published: 2013

Journal Articles

CH50 Activity Correlates with Residual Intravascular Hemolysis in Pts with Paroxysmal Nocturnal Hemoglobinuria Treated by Eculizumab

Regis Peffault de Latour, Veronique Fremeaux-Bacchi, MD, PhD, Raphael Porcher, PhD, Paula Rodriguez-Otero, Stephane Roncellin, Sarah Abbes, Gerard Socie

Blood (2012) 120 (21): 3193.

https://doi.org/10.1182/blood.V120.21.3193.3193

Published: 2012

Journal Articles

A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function

Lubka T. Roumenina, Marie Frimat, Elizabeth C. Miller, Francois Provot, Marie-Agnes Dragon-Durey, Pauline Bordereau, Sylvain Bigot, Christophe Hue, Simon C. Satchell, Peter W. Mathieson, Christiane Mousson, Christian Noel, Catherine Sautes-Fridman, Lise Halbwachs-Mecarelli, John P. Atkinson, Arnaud Lionet, Veronique Fremeaux-Bacchi

Blood (2012) 119 (18): 4182–4191.

https://doi.org/10.1182/blood-2011-10-383281

Published: 2012

Journal Articles

Complement alternative pathway acts as a positive feedback amplification of neutrophil activation

Laurent Camous, Lubka Roumenina, Sylvain Bigot, Soumeya Brachemi, Véronique Frémeaux-Bacchi, Philippe Lesavre, Lise Halbwachs-Mecarelli

Blood (2011) 117 (4): 1340–1349.

https://doi.org/10.1182/blood-2010-05-283564

Published: 2011

Journal Articles

Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome

Lubka T. Roumenina, Mathieu Jablonski, Christophe Hue, Jacques Blouin, Jordan D. Dimitrov, Marie-Agnes Dragon-Durey, Mathieu Cayla, Wolf H. Fridman, Marie-Alice Macher, David Ribes, Luc Moulonguet, Lionel Rostaing, Simon C. Satchell, Peter W. Mathieson, Catherine Sautes-Fridman, Chantal Loirat, Catherine H. Regnier, Lise Halbwachs-Mecarelli, Veronique Fremeaux-Bacchi

Blood (2009) 114 (13): 2837–2845.

https://doi.org/10.1182/blood-2009-01-197640

Published: 2009

Includes: Supplemental data

NARROW

Rare germline complement factor H variants in patients with paroxysmal nocturnal hemoglobinuria

How I diagnose and treat atypical hemolytic uremic syndrome

Characterization of Patients with aHUS and Triggering/Associated Events, with and without Complement Pathogenic Variants or Anti-Cfh Antibodies: A Global aHUS Registry Analysis

COVID-19 as a potential trigger of complement-mediated atypical HUS

Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study

Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group

Treatment of Delayed Hemolytic Transfusion Reactions in Sickle Cell Disease Patients By an Anti-C5 Antibody

Treatment of B-cell disorder improves renal outcome of patients with monoclonal gammopathy–associated C3 glomerulopathy

Eculizumab salvage therapy for delayed hemolysis transfusion reaction in sickle cell disease patients

The Global aHUS Registry: Characteristics of 826 Patients with Atypical Hemolytic Uremic Syndrome

Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome

Loss of DGKε induces endothelial cell activation and death independently of complement activation

Assessing complement blockade in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab

Baseline Demographics and Characteristics of 466 Patients with Atypical Hemolytic Uremic Syndrome in the Global aHUS Registry

The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status

Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome

CH50 Activity Correlates with Residual Intravascular Hemolysis in Pts with Paroxysmal Nocturnal Hemoglobinuria Treated by Eculizumab

A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function

Complement alternative pathway acts as a positive feedback amplification of neutrophil activation

Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome

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American Society of Hematology

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ASH Publications

American Society of Hematology

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