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Journal Articles

Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa

Peter Olupot-Olupot, George Tomlinson, Thomas N. Williams, Léon Tshilolo, Brígida Santos, Luke R. Smart, Kathryn McElhinney, Thad A. Howard, Banu Aygun, Susan E. Stuber, Adam Lane, Teresa S. Latham, Russell E. Ware

Blood (2023) 141 (12): 1402–1410.

https://doi.org/10.1182/blood.2022017051

Published: 2023

Includes: Supplemental data

Journal Articles

Hydroxyurea to Reduce Stroke Risk in Tanzanian Children with Sickle Cell Anemia

Emmanuela E. Ambrose, MD, Luke R. Smart, MD, Primrose Songoro, RN, Idd Shabani, MD, Protas Komba, MD, Mwesige Charles, BScHLS, Thad A. Howard, MS, Susan E. Stuber, MA, Adam Lane, PhD, Teresa Latham, MA, Abel Nkono Makubi, PhD MD MSc, Russell E. Ware, MD PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-135944

Published: 2020

Journal Articles

Genetic Variants That Influence Fetal Hemoglobin Expression from Hydroxyurea Treatment

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-143139

Published: 2020

Journal Articles

Genetic Basis of Erythrocyte Alloimmunization Among Children with Sickle Cell Anemia in the Dominican Republic

Kristina Prus, MD, Rosa M. Nieves, MD, Thad A. Howard, MS, Susan E. Stuber, MA, Rafael Mena, MD, Teresa Latham, MA, Russell E. Ware, MD PhD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-142015

Published: 2020

Journal Articles

Novel Genetic Loci That Influence Fetal Hemoglobin Expression in Children with Sickle Cell Anemia

Anu Marahatta, PhD, Thad A. Howard, MS, Susan E. Stuber, MA, Kathryn L McElhinney, BS, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Brigida Santos, MD, Chandy C. John, MD MS, Robert Opoka, MMED, Rosa M. Nieves, MD, Rafael Mena, MD, Jasmine Baker, PhD, Teresa Latham, MA, Jonathan M. Flanagan, PhD, Russell E. Ware, MD PhD

Blood (2020) 136 (Supplement 1): 33–34.

https://doi.org/10.1182/blood-2020-143025

Published: 2020

Journal Articles

Hydroxyurea Pharmacokinetic Profiles in Children Treated for Extreme Thrombocytosis after Total Pancreatectomy with Islet Cell Autotransplant Demonstrate Poor Absorption

Alexander A Boucher, MD, Min Dong, PhD, Anu Marahatta, PhD, Adriane Hausfeld, Thad A. Howard, MS, Jaimie D Nathan, MD, Alexander A. Vinks, PharmD, PhD FCP, Patrick T. McGann, MD, Russell E. Ware, MD PhD, Lori Luchtman-Jones, MD

Blood (2019) 134 (Supplement_1): 4893.

https://doi.org/10.1182/blood-2019-127378

Published: 2019

Journal Articles

Genetic Analysis in the Tanzania Sickle Surveillance Study (TS3): Modifiers of Sickle Cell Disease and Identification of Hemoglobin Variants

Luke R. Smart, MD, Emmanuela E. Ambrose, MD, Mwesige Charles, BScHLS, Arielle G. Hernandez, MPH, Teresa S. Latham, MA, Adolfine Hokororo, MD MMed, MSc, Medard Beyanga, BLS, MSc, Erasmus Kamugisha, MD MSc, PhD, Erius Tebuka, MD MMed, Thad A. Howard, MS, Russell E. Ware, MD PhD

Blood (2019) 134 (Supplement_1): 988.

https://doi.org/10.1182/blood-2019-128554

Published: 2019

Journal Articles

Geospatial Mapping of Sickle Cell Disease in Northwest Tanzania: The Tanzania Sickle Surveillance Study (TS3)

Emmanuela E. Ambrose, MD, Luke R. Smart, MD, Mwesige Charles, BScHLS, Arielle G. Hernandez, MPH, Adolfine Hokororo, MD MMed, MSc, Teresa Latham, MA, Medard Beyanga, BLS, MSc, Erius Tebuka, MD MMed, Erasmus Kamugisha, MD MSc, PhD, Thad A. Howard, MS, Russell E. Ware, MD PhD

Blood (2018) 132 (Supplement 1): 3662.

https://doi.org/10.1182/blood-2018-99-113939

Published: 2018

Journal Articles

A Simple, Rapid, and Inexpensive Color-Based Hemoglobin Assay As a Robust Screening Test for Severe Anemia in Limited Resource Settings

Marina Perez-Plazola, Erika Tyburski, BS, Luke R. Smart, MD, Thad A. Howard, MS, Sophie Perier, BS MS, Russell E. Ware, MD PhD, Wilbur A Lam, MD PhD, Patrick T. McGann, MD

Blood (2018) 132 (Supplement 1): 4724.

https://doi.org/10.1182/blood-2018-99-112898

Published: 2018

Journal Articles

Personalized Hydroxyurea Dosing to Reduce Time to MTD and Optimize the HbF Response: Results from the TREAT Study

Patrick T. McGann, MD MS, Omar Niss, MD, Min Dong, PhD, Anu Marahatta, PhD, Kathryn L McElhinney, BS, Thad A. Howard, MS, Tomoyuki Mizuno, PhD, Theodosia A. Kalfa, MD PhD, Karen Kalinyak, MD, Punam Malik, MD, Charles T. Quinn, MD MS, Russell E. Ware, MD PhD, Alexander A. Vinks, PharmD, PhD FCP

Blood (2017) 130 (Supplement 1): 615.

https://doi.org/10.1182/blood.V130.Suppl_1.615.615

Published: 2017

Journal Articles

Individualized Dosing of Hydroxyurea for Children with Sickle Cell Anemia Using a Population Pharmacokinetic-Based Model: The TREAT Study

Patrick T. McGann, MD MS, Min Dong, PhD, Anu Marahatta, PhD, Thad A. Howard, MS, Tomoyuki Mizuno, PhD, Karen A. Kalinyak, MD, Theodosia A. Kalfa, MD PhD, Punam Malik, MD, Omar Niss, MD, Charles T Quinn, MD, Russell E. Ware, MD PhD, Alexander A. Vinks, PharmD, PhD

Blood (2016) 128 (22): 3652.

https://doi.org/10.1182/blood.V128.22.3652.3652

Published: 2016

Journal Articles

Genetic Causes of Anemia in Malawian Children Less Than 5 Years of Age: Results from the Malawi Demographic and Health Survey

Patrick T. McGann, MD MS, Anne M. Williams, MPH, Kathryn E. McElhinney, BS, Laurel Romano, Julia Woodall, Thad A. Howard, MS, Graham Ellis, Carine Mapango, Ben Chilima, PhD, Russell E. Ware, MD PhD, Parminder S. Suchdev, MD MPH

Blood (2016) 128 (22): 313.

https://doi.org/10.1182/blood.V128.22.313.313

Published: 2016

Journal Articles

Genetic Analyses in the Uganda Sickle Surveillance Study: Modifiers of Sickle Cell Anemia and Identification of Hemoglobin Variants

Beverly A Schaefer, MD, Charles Kiyaga, MS MPhil, Thad A. Howard, MS, Grace Ndeezi, MBChB PhD, Arielle G Hernandez, MPH, Isaac Ssewanyana, MS, Mary C. Paniagua, MA, Christopher Ndugwa, MBChB, Jane Aceng, MBChB MPH, Russell E. Ware, MD PhD

Blood (2016) 128 (22): 2479.

https://doi.org/10.1182/blood.V128.22.2479.2479

Published: 2016

Journal Articles

Effects of Genetic Polymorphisms on Leukocyte and Neutrophil Counts and Maximum Tolerated Dose of Hydroxyurea in Children with Sickle Cell Anemia

Beverly A Schaefer, MD, Jonathan M Flanagan, PhD, Thad A. Howard, MS, Kerri A Nottage, MD MPH, Connie M. Piccone, MD, Scott T. Miller, MD, Alex George, MD, PhD, Beatrice E. Gee, MD, Barry R Davis, MDPhD, Russell E. Ware, MD PhD

Blood (2015) 126 (23): 2165.

https://doi.org/10.1182/blood.V126.23.2165.2165

Published: 2015

Journal Articles

Accuracy of a Rapid and Simple Point-of-Care Test for Sickle Cell Disease

Patrick T. McGann, MD MS, Beverly A. Schaefer, MD, Mary C. Paniagua, MA, Thad A. Howard, MS, Russell E. Ware, MD PhD

Blood (2015) 126 (23): 2182.

https://doi.org/10.1182/blood.V126.23.2182.2182

Published: 2015

Journal Articles

Genetic Modifiers Influencing the Development of Albuminuria in Children with Sickle Cell Anemia

Beverly A Schaefer, MD, Jonathan M Flanagan, PhD, Banu Aygun, MD, Ofelia A. Alvarez, MD, Stephen C Nelson, MD, Kerri A Nottage, MD MPH, Carla W Roberts, MD, Thad A. Howard, MS, Barry R Davis, MDPhD, Russell E. Ware, MD PhD

Blood (2015) 126 (23): 3393.

https://doi.org/10.1182/blood.V126.23.3393.3393

Published: 2015

Journal Articles

Pharmacokinetics and Tissue Distribution of Hydroxyurea in a Mouse Model

Anu Marahatta, Kathryn McElhinney, Thad A. Howard, MS, Russell E. Ware, MD PhD

Blood (2015) 126 (23): 4579.

https://doi.org/10.1182/blood.V126.23.4579.4579

Published: 2015

Journal Articles

Hydroxyurea Pharmacokinetics for Predicting Maximum Tolerated Dose in Children with Sickle Cell Anemia

Patrick T. McGann, MDMS, Alex Sparreboom, PhD, Nicole A Mortier, MHS, PA-C, Banu Aygun, MD, Thad A Howard, MS, Kerri Nottage, MD MPH, Russell E. Ware, MD PhD

Blood (2014) 124 (21): 2707.

https://doi.org/10.1182/blood.V124.21.2707.2707

Published: 2014

Journal Articles

Effect Of Genetic Modifiers Of Baseline Fetal Hemoglobin On Hydroxyurea Response In Children With Sickle Cell Disease

Vivien A Sheehan, MD, PhD, Jacy R Crosby, MS, Jonathan Michael Flanagan, Ph.D, Thad A Howard, MS, Nicole A. Mortier, MHS, PA-C, Banu Aygun, MD, Russell E. Ware, MD, PhD

Blood (2013) 122 (21): 2216.

https://doi.org/10.1182/blood.V122.21.2216.2216

Published: 2013

Journal Articles

FOXO3 Variants Are Associated With Lower Fetal Hemoglobin Levels In Children With Sickle Cell Disease

Vivien A Sheehan, MD, PhD, Jacy R Crosby, MS, Aniko Sabo, PhD, Thad A Howard, MS, Donna M. Muzny, Jeffrey G Reid, Ph.D, Banu Aygun, MD, Eric Boerwinkle, PhD, Richard A. Gibbs, Russell E. Ware, MD, PhD

Blood (2013) 122 (21): 778.

https://doi.org/10.1182/blood.V122.21.778.778

Published: 2013

NARROW

Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa

Hydroxyurea to Reduce Stroke Risk in Tanzanian Children with Sickle Cell Anemia

Genetic Variants That Influence Fetal Hemoglobin Expression from Hydroxyurea Treatment

Genetic Basis of Erythrocyte Alloimmunization Among Children with Sickle Cell Anemia in the Dominican Republic

Novel Genetic Loci That Influence Fetal Hemoglobin Expression in Children with Sickle Cell Anemia

Hydroxyurea Pharmacokinetic Profiles in Children Treated for Extreme Thrombocytosis after Total Pancreatectomy with Islet Cell Autotransplant Demonstrate Poor Absorption

Genetic Analysis in the Tanzania Sickle Surveillance Study (TS3): Modifiers of Sickle Cell Disease and Identification of Hemoglobin Variants

Geospatial Mapping of Sickle Cell Disease in Northwest Tanzania: The Tanzania Sickle Surveillance Study (TS3)

A Simple, Rapid, and Inexpensive Color-Based Hemoglobin Assay As a Robust Screening Test for Severe Anemia in Limited Resource Settings

Personalized Hydroxyurea Dosing to Reduce Time to MTD and Optimize the HbF Response: Results from the TREAT Study

Individualized Dosing of Hydroxyurea for Children with Sickle Cell Anemia Using a Population Pharmacokinetic-Based Model: The TREAT Study

Genetic Causes of Anemia in Malawian Children Less Than 5 Years of Age: Results from the Malawi Demographic and Health Survey

Genetic Analyses in the Uganda Sickle Surveillance Study: Modifiers of Sickle Cell Anemia and Identification of Hemoglobin Variants

Effects of Genetic Polymorphisms on Leukocyte and Neutrophil Counts and Maximum Tolerated Dose of Hydroxyurea in Children with Sickle Cell Anemia

Accuracy of a Rapid and Simple Point-of-Care Test for Sickle Cell Disease

Genetic Modifiers Influencing the Development of Albuminuria in Children with Sickle Cell Anemia

Pharmacokinetics and Tissue Distribution of Hydroxyurea in a Mouse Model

Hydroxyurea Pharmacokinetics for Predicting Maximum Tolerated Dose in Children with Sickle Cell Anemia

Effect Of Genetic Modifiers Of Baseline Fetal Hemoglobin On Hydroxyurea Response In Children With Sickle Cell Disease

FOXO3 Variants Are Associated With Lower Fetal Hemoglobin Levels In Children With Sickle Cell Disease

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American Society of Hematology

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American Society of Hematology

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