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Tariq Enver, PhD
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Journal Articles

Mitochondrial Activity Identifies a Transcriptionally and Functionally Distinct Subset of Aged HSCs with Lineage-Balanced Output

Els Mansell, PhD, Valgardur Sigurdsson, PhD, Elitza Deltcheva, PhD, John Brown, PhD, Chela James, PhD, Kenichi Miharada, PhD, Shamit Soneji, PhD, Jonas Larsson, MD PhD, Tariq Enver, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2480.
https://doi.org/10.1182/blood-2019-124001
Published: 2019
Journal Articles

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Ifat Geron, PhD, Angela Maria Savino, PhD, Noa Tal, MD PhD, John Brown, PhD, Virginia A Turati, DPhil, Yu Nee Lee, PhD, Chela James, PhD, Avigail Rein Gil, MD, Yehudit Birger, PhD, Inna Muler, Michal Hameiri, PhD, Victoria Marcu-Malina, PhD, Ute Fischer, PhD, Arndt Borkhardt, MD, Ilan M. Kirsch, MD, Arnon Nagler, MD, Tariq Enver, PhD, Shai Izraeli, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 566.
https://doi.org/10.1182/blood-2018-99-115913
Published: 2018
Journal Articles

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction As a Developmental Susceptibility to ETV6-RUNX1

Simon E Richardson, MA, MD PhD MRCP, FRPATH, Charlotta Boiers, MDPhD, Alya Zriwil, PhD, Emma Laycock, Virginia A Turati, DPhil, John Brown, PhD, Jason Wray, PhD, Chela James, PhD, Dapeng Wang, PhD, Javier Herrero, PhD, Ewa Sitnicka, PhD, Stefan Karlsson, MD, Andrew J.H. Smith, PhD, Sten Eirik Jacobsen, MDPhD, Tariq Enver, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1218.
https://doi.org/10.1182/blood.V130.Suppl_1.1218.1218
Published: 2017
Journal Articles

Transgenic Zebrafish Expressing the Human TEL-AML1 Oncogene Have Aberrant Developmental Myelopoiesis

Oscar Pena, Catherine Hockings, MBBChir, MA, FRCPath, MRCP, Gregorio Contento, Jasmine Rowell, Hatem Sabaawy, MD PhD, Tariq Enver, PhD, Elspeth M Payne, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2711.
https://doi.org/10.1182/blood.V128.22.2711.2711
Published: 2016
Journal Articles

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

Virginia A Turati, PhD, José Afonso Guerra-Assunção, PhD, John C Ambrose, PhD, John Brown, PhD, Mike Hubank, PhD, Alex Hobbs, PhD, Mark Lynch, PhD, Bernadett Gaal, PhD, Sarah Inglott, Lucia Conde, PhD, Simon Richardson, MD PhD, Javier Herrero, PhD, Sten Eirik Jacobsen, MD PhD, Tariq Enver, PhD
Journal: Blood
Blood (2016) 128 (22): 606.
https://doi.org/10.1182/blood.V128.22.606.606
Published: 2016
Journal Articles

VEGFA- a New Therapeutic Target in CNS Leukemia

Itaru Kato, MD, PhD, Yoko Nishinaka-Arai, PhD, Masahiro Nakamura, MD PhD, Ayse U. Akarca, BSc, Akira Niwa, MD, PhD, Hiroki Ozawa, Kenichi Yoshida, MD PhD, Makiko Mori, MD, Dapeng Wang, PhD, Hiroo Ueno, MD, Yusuke Shiozawa, MD, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Rajeev Gupta, MD, PhD, Katsutsugu Umeda, MD PhD, Kenichiro Watanabe, MD PhD, Katsuyoshi Koh, MD PhD, Souichi Adachi, MD, PhD, Toshio Heike, MDPhD, Megumu K Saito, MD, PhD, Masashi Sanada, MD PhD, Seishi Ogawa, MD PhD, Teresa Marafioti, MD, Akira Watanabe, PhD, Tatsutoshi Nakahata, MD PhD, Tariq Enver, PhD
Journal: Blood
Blood (2016) 128 (22): 911.
https://doi.org/10.1182/blood.V128.22.911.911
Published: 2016
Journal Articles

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Nicolas Goardon, Emmanuele Marchi, Lynn Quek, Anna Schuh, Petter Woll, Adam Mead, Kate Alford, Amanda Gilkes, Kheira Beldjord, David Bowen, Graham Standen, Sally Killick, Hannah Hunter, Steven Knapper, Lisa Robinson, Alex Sternberg, James D Cavenagh, Paul Virgo, Mike Griffiths, Elizabeth A. Macintyre, PhD, FRCP, FRCPath, Charles Craddock, Alan Burnett, Tariq Enver, PhD, Sten Eirik W Jacobsen, Catherine Porcher, Paresh Vyas
Journal: Blood
Blood (2010) 116 (21): 91.
https://doi.org/10.1182/blood.V116.21.91.91
Published: 2010
Journal Articles

Selective Persistence of Distinct Stem/B Leukaemic Stem Cells In Childhood Acute Lymphoblastic Leukaemia In Clinical Remission.

Christoph Lutz, MD, Petter Woll, PhD, Anders Castor, MD, PhD, Helen Ferry, PhD, Christina Jensen, PhD, Joanne Green, Helene Dreau, Michael Lutteropp, Anna Schuh, MD, PhD, Georgina Hall, MD, PhD, Chris Mitchell, MD, PhD, Jan Zuna, MD, PhD, Veronica Buckle, PhD, Sten Eirik W Jacobsen, MD, PhD, Tariq Enver, PhD
Journal: Blood
Blood (2010) 116 (21): 1585.
https://doi.org/10.1182/blood.V116.21.1585.1585
Published: 2010
Journal Articles

Dysregulation of Pax5 Activity Contributes to the Extinction of the B-Cell Phenotype in Reed-Sternberg Cells

Graham P Collins, MD, Jennifer C Paterson, Gillian E May, PhD, Rajeev Gupta, MD, PhD, Teresa Marafioti, MD, David Y Mason, MD, PhD, Tariq Enver, PhD
Journal: Blood
Blood (2008) 112 (11): 517.
https://doi.org/10.1182/blood.V112.11.517.517
Published: 2008
Journal Articles

Ectopic Expression of HDAC9 in Murine Lymphoid System Leads to Altered Lymphocyte Numbers and Proliferation as Well as Predisposition to Tumorigenesis.

Veronica S. Gil, BSc, Louise M.C. Howell, BSc, Jenny Yeung, PhD, Kevin R. Petrie, PhD, Adrian Smith, PhD, Neil Sebire, MD, Estela Matutes, MD, PhD, Andy Wotherspoon, MD, Tariq Enver, PhD, Eric So, PhD, Arthur Zelent, PhD
Journal: Blood
Blood (2007) 110 (11): 376.
https://doi.org/10.1182/blood.V110.11.376.376
Published: 2007
Journal Articles

Deregulation of RARγ and RARγ-Specific miRNAs in AML.

Angela N. Barrett, PhD, Rajeev Gupta, MD, Annegret Glasow, PhD, David Grimwade, PhD, Marieke von Lindern, PhD, Samuel Waxman, MD, Ken Mills, PhD, FRCPath, Alan Burnett, PhD, Tariq Enver, PhD, Arthur Zelent, PhD
Journal: Blood
Blood (2007) 110 (11): 3182.
https://doi.org/10.1182/blood.V110.11.3182.3182
Published: 2007
Journal Articles

DNA Methylation Independent Silencing of the RAR α Gene Expression in Acute Myeloid Leukemia.

Annegret Glasow, PhD, Angela Barrett, PhD, Manuel Boix Chornet, PhD, Rajeev Gupta, MD, Da-cheng Zhou, PhD, Robert Gallagher, MD, Marieke von Lindern, PhD, Samuel Waxman, MD, Tariq Enver, PhD, Guido Hildebrandt, MD, Arthur Zelent, PhD
Journal: Blood
Blood (2006) 108 (11): 2225.
https://doi.org/10.1182/blood.V108.11.2225.2225
Published: 2006
Journal Articles

Expression of ATRA Inducible RARα2 Isoform Is Deregulated in AML.

Annegret Glasow, PhD, Angela Barrett, PhD, Rajeev Gupta, MD, David Grimwade, MD, Marieke von Lindern, PhD, Tariq Enver, PhD, Arthur Zelent, PhD
Journal: Blood
Blood (2005) 106 (11): 1204.
https://doi.org/10.1182/blood.V106.11.1204.1204
Published: 2005
Journal Articles

Transcriptional Programming in Quiescent Human Hematopoietic Stem Cells - Implications for Regulation of Lineage Commitment Decisions.

Cristina Pina, MD, Tariq Enver, PhD
Journal: Blood
Blood (2005) 106 (11): 1723.
https://doi.org/10.1182/blood.V106.11.1723.1723
Published: 2005
Journal Articles

Mathematical Modeling of Transcriptional Regulatory Circuits Defines Cell Fate Attractors and Predicts the Genome-Scale Behaviour of Haemopoietic Progenitor Cells Undergoing a Binary Cell Fate Decision.

Tariq Enver, PhD, Sui Huang, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 4219.
https://doi.org/10.1182/blood.V106.11.4219.4219
Published: 2005
Journal Articles

Directing Oncogenic Fusion Genes into Stem Cells Via an Scl Enhancer.

Mariko Eguchi, MD PhD, Minenori Eguchi-Ishimae, MD PhD, Anthony R. Green, PhD FRCP FRCPath, Tariq Enver, PhD, Mel Greaves, FRS
Journal: Blood
Blood (2004) 104 (11): 216.
https://doi.org/10.1182/blood.V104.11.216.216
Published: 2004