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Takafumi Shimizu
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Journal Articles

Preclinical Evaluation of a Novel Orally Bioavailable Menin-MLL Interaction Inhibitor, DSP-5336, for the Treatment of Acute Leukemia Patients with MLL -Rearrangement or NPM1 Mutation

Ken Eguchi, Takafumi Shimizu, Daiki Kato, Yudai Furuta, Seiji Kamioka, Hitoshi Ban, Setsuko Ymamoto, Akihiko Yokoyama, Issay Kitabayashi
Journal: Blood
Blood (2021) 138 (Supplement 1): 3339.
https://doi.org/10.1182/blood-2021-152050
Published: 2021
Journal Articles

Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2 -V617F mouse model of MPN

Jean Grisouard, Takafumi Shimizu, Adrian Duek, Lucia Kubovcakova, Hui Hao-Shen, Stephan Dirnhofer, Radek C. Skoda
Journal: Blood
Blood (2015) 125 (13): 2131–2140.
https://doi.org/10.1182/blood-2014-08-594572
Published: 2015
Includes: Supplemental data
Journal Articles

JAK2V617F and Loss of Ezh2 in Hematopoietic Cells Contribute Synergistically to Myeloproliferative Neoplasm Initiation Potential, and Accelerate Progression of Disease

Takafumi Shimizu, PhD, Hui Hao-Shen, Lucia Kubovcakova, PhD, Pontus Lundberg, PhD, Stephan Dirnhofer, Stuart H. Orkin, MD, Jean Grisouard, PhD, Yukiko Shimizu, Annalisa Pianta, PhD, Barbara Szczerba, Ronny Nienhold, Radek C. Skoda, MD
Journal: Blood
Blood (2014) 124 (21): 158.
https://doi.org/10.1182/blood.V124.21.158.158
Published: 2014
Journal Articles

Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2 -V617F–driven mouse model of MPNs

Adrian Duek, Pontus Lundberg, Takafumi Shimizu, Jean Grisouard, Axel Karow, Lucia Kubovcakova, Hui Hao-Shen, Stephan Dirnhofer, Radek C. Skoda
Journal: Blood
Blood (2014) 123 (25): 3943–3950.
https://doi.org/10.1182/blood-2013-07-514208
Published: 2014
Journal Articles

Hereditary Thrombocytosis Caused By a Novel Germ-Line Mutation In The Gelsolin Gene

Annalisa Pianta, PhD, Kun Liu, PhD, Pontus Lundberg, PhD, Takafumi Shimizu, PhD, Hui Hao-Shen, Stephan Dirnhofer, MD, Robert Kralovics, PhD, Amy D. Shapiro, MD, Radek C. Skoda, M.D.
Journal: Blood
Blood (2013) 122 (21): 265.
https://doi.org/10.1182/blood.V122.21.265.265
Published: 2013
Journal Articles

Epigenetic Memory Enables the Dominant Generation of Adult-Type Erythrocytes From Human Induced Pluripotent Stem Cells

Naoya Takayama, M.D., Ph.D., Shiya Sano, Takafumi Shimizu, Ryoichiro Kawahata, Hiroshi Endo, M.D., Sou Nakamura, Seishi Ogawa, MD, PhD, Hiromitsu Nakauchi, Koji Eto, M.D., Ph.D.
Journal: Blood
Blood (2010) 116 (21): 648.
https://doi.org/10.1182/blood.V116.21.648.648
Published: 2010
Journal Articles

Generation of Monoclonal TCR-Expressing Human T-Lineage Lymphocytes From Induced Pluripotent Stem Cells of Single Peripheral T-Lymphocyte Origin

Toshinobu Nishimura, Shin Kaneko, M.D., Ph.D., Haruo Gotoh, Naoya Takayama, M.D., Ph.D., Takafumi Shimizu, Shoichi Iriguchi, Yoko Tajima, Yutaka Yasui, Nobukazu Watanabe, M.D., Ph.D., Satoshi Takahashi, M.D., Ph.D., Koji Eto, M.D., Ph.D., Hiromitsu Nakauchi, M.D., Ph.D.
Journal: Blood
Blood (2010) 116 (21): 490.
https://doi.org/10.1182/blood.V116.21.490.490
Published: 2010
Journal Articles

Establishment of Mouse PMF Model by the Introduction of Constitutive STAT5a Into Purified Hematopoietic Stem Cells.

Takafumi Shimizu, Akihiko Ito, Akira Nakagawa, Toshinobu Nishimura, Satoshi Yamazaki, Shoichi Iriguchi, Shin Kaneko, Hiromitsu Nakauchi
Journal: Blood
Blood (2009) 114 (22): 3900.
https://doi.org/10.1182/blood.V114.22.3900.3900
Published: 2009