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Sou Nakamura
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Journal Articles

iPSC-Derived Mesenchymal Stem Cells Supports the Ex Vivo expansion of Human Hematopoietic Stem and Progenitor Cells Via Sterile Inflammation Pathway

Maria Alejandra Kanashiro, Sudip Kumar Paul, Masamitsu Sone, Ikuyo Yoshino, Kyoko Tsujimura, Makoto Ikeya, Sou Nakamura, Koji Eto, Naoya Takayama
Journal: Blood
Blood (2023) 142 (Supplement 1): 2680.
https://doi.org/10.1182/blood-2023-181378
Published: 2023
Journal Articles

iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study

Clinical Trials & Observations
Naoshi Sugimoto, Junya Kanda, Sou Nakamura, Toshiyuki Kitano, Masakatsu Hishizawa, Tadakazu Kondo, Shin Shimizu, Akiko Shigemasa, Hideyo Hirai, Yasuyuki Arai, Manabu Minami, Harue Tada, Dai Momose, Ki-Ryang Koh, Masayuki Nogawa, Naohide Watanabe, Shinichiro Okamoto, Makoto Handa, Akira Sawaguchi, Nobuki Matsuyama, Mitsunobu Tanaka, Tomoya Hayashi, Akihiro Fuchizaki, Yoshihiko Tani, Akifumi Takaori-Kondo, Koji Eto
Journal: Blood
Blood (2022) 140 (22): 2398–2402.
https://doi.org/10.1182/blood.2022017296
Published: 2022
Includes: Supplemental data
Journal Articles

The First-in-Human Clinical Trial of iPSC-Derived Platelets (iPLAT1): Autologous Transfusion to an Aplastic Anemia Patient with Alloimmune Platelet Transfusion Refractoriness

Naoshi Sugimoto, Junya Kanda, Sou Nakamura, Toshiyuki Kitano, Masakatsu Hishizawa, Tadakazu Kondo, Shin Shimizu, Akiko Shigemasa, Hideyo Hirai, Harue Tada, Manabu Minami, Naohide Watanabe, Masayuki Nogawa, Makoto Handa, Yoshihiko Tani, Akifumi Takaori-Kondo, Koji Eto
Journal: Blood
Blood (2021) 138 (Supplement 1): 351.
https://doi.org/10.1182/blood-2021-145814
Published: 2021
Journal Articles

Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Akinori Yuzuriha, Sou Nakamura, PhD, Toshie Kusunoki, Takuya Matsumoto, PhD, Naoshi Sugimoto, MD PhD, Kiyotoshi Sekiguchi, PhD, Koji Eto, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3845.
https://doi.org/10.1182/blood-2018-99-114505
Published: 2018
Journal Articles

Anagrelide Inhibits Proliferation and Platelet Generation in Immortalized Megakaryocyte Progenitor Cell Lines Established from Human Induced Pluripotent Stem Cells

Koji Takaishi, MD, Masahiro Takeuchi, MD PhD, Shokichi Tsukamoto, MD PhD, Naoya Takayama, MD PhD, Motohiko Oshima, PhD, Yusuke Isshiki, MD, Kensuke Kayamori, MD, Kenji Kimura, MD, Yutaro Hino, MD, Nagisa Oshima-Hasegawa, MD PhD, Shio Mitsukawa, MD PhD, Yusuke Takeda, MD PhD, Naoya Mimura, MD PhD, Chikako Ohwada, MD PhD, Tohru Iseki, MD PhD, Sou Nakamura, PhD, Koji Eto, MD PhD, Atsushi Iwama, MD PhD, Koutaro Yokote, MD PhD, Chiaki Nakaseko, MDPhD, Emiko Sakaida, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1789.
https://doi.org/10.1182/blood-2018-99-111683
Published: 2018
Journal Articles

Natural Killer Cell Activities Against iPSCs-Derived HLA-Knockout Platelets and Megakaryocytes Reveal Perfect Rejection Profiles for Allotransfusion

Daisuke Suzuki, Naoshi Sugimoto, MD PhD, Norihide Yoshikawa, Hiroshi Endo, Sou Nakamura, Akitsu Hotta, Koji Eto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3841.
https://doi.org/10.1182/blood.V128.22.3841.3841
Published: 2016
Journal Articles

High-Vorticity with Periodic Flow Enhances in Vitro Biogenesis of Healthy Platelets from iPSC-Derived-Megakaryocytes

Yukitaka Ito, Sou Nakamura, Tomohiro Shigemori, Naoshi Sugimoto, MD PhD, Yoshikazu Kato, Kazuya Hashimoto, Naohide Watanabe, Masayuki Nogawa, Makoto Handa, Satoshi Nishimura, Koji Eto
Journal: Blood
Blood (2016) 128 (22): 2181.
https://doi.org/10.1182/blood.V128.22.2181.2181
Published: 2016
Journal Articles

Platelet Production System Using An Immortalized Megakaryocyte Cell Line Derived From Human Pluripotent Stem Cells

Sou Nakamura, Naoya Takayama, M.D., Ph.D., Hiromitsu Nakauchi, MD, PhD, Koji Eto, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): MRG-1.
https://doi.org/10.1182/blood.V118.21.MRG-1.MRG-1
Published: 2011
Journal Articles

Direct and Continuous Inhibition of ADAM17 Using a Novel Selective Inhibitor Restores Functional Platelet Yield From Human Pluripotent Stem Cells

Shinji Hirata, Ryoko Jono-Ohnishi, Satoshi Nishimura, M.D., Ph.D, Naoya Takayama, M.D., Ph.D., Sou Nakamura, Hiromitsu Nakauchi, MD, PhD, Takahiko Murata, Ph.D., Koji Eto, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 2323.
https://doi.org/10.1182/blood.V118.21.2323.2323
Published: 2011
Journal Articles

Platelet Production System Using An Immortalized Megakaryocyte Cell Line Derived From Human Pluripotent Stem Cells

Sou Nakamura, Naoya Takayama, M.D., Ph.D., Hiromitsu Nakauchi, MD, PhD, Koji Eto, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 2.
https://doi.org/10.1182/blood.V118.21.2.2
Published: 2011
Journal Articles

Modeling Congenital Amegakaryocytic Thrombocytopenia Using Patient-Specific Induced Pluripotent Stem Cells

Naoya Takayama, M.D., Ph.D., Shinji Hirata, Ryoko Jono-Ohnishi, Sou Nakamura, Sho-ichi Hirose, Hiroshi Endo, M.D., Masanori Nishi, MD, Yuhei Hamazaki, Shin Kaneko, M.D., Ph.D., Eiichi Ishii, MD, PhD, Hiromitsu Nakauchi, MD, PhD, Shinji Kunishima, PhD, Koji Eto, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 703.
https://doi.org/10.1182/blood.V118.21.703.703
Published: 2011
Journal Articles

Epigenetic Memory Enables the Dominant Generation of Adult-Type Erythrocytes From Human Induced Pluripotent Stem Cells

Naoya Takayama, M.D., Ph.D., Shiya Sano, Takafumi Shimizu, Ryoichiro Kawahata, Hiroshi Endo, M.D., Sou Nakamura, Seishi Ogawa, MD, PhD, Hiromitsu Nakauchi, Koji Eto, M.D., Ph.D.
Journal: Blood
Blood (2010) 116 (21): 648.
https://doi.org/10.1182/blood.V116.21.648.648
Published: 2010
Journal Articles

Cancellation of c-MYC Silencing in Human Induced Pluripotent Stem Cells Contributes to the Efficient in Vitro Production of Platelets with the Ability of Hemostasis In Vivo.

Naoya Takayama, Sou Nakamura, Satoshi Nishimura, Ryoko Ohnishi, Kazutoshi Takahashi, Shinya Yamanaka, Koji Eto, Hiromitsu Nakauchi
Journal: Blood
Blood (2009) 114 (22): 1488.
https://doi.org/10.1182/blood.V114.22.1488.1488
Published: 2009