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Journal Articles

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

Marie Bellio, Cédric Garcia, Thomas Edouard, Sophie Voisin, Benjamin G. Neel, Cendrine Cabou, Philippe Valet, Jun Mori, Alexandra Mazharian, Yotis A. Senis, Armelle Yart, Bernard Payrastre, Sonia Severin
Journal: Blood
Blood (2019) 134 (25): 2304–2317.
https://doi.org/10.1182/blood.2019001543
Published: 2019
Includes: Supplemental data
Journal Articles

A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth

Colin Valet, Marie Levade, Gaëtan Chicanne, Benoit Bilanges, Cendrine Cabou, Julien Viaud, Marie-Pierre Gratacap, Frédérique Gaits-Iacovoni, Bart Vanhaesebroeck, Bernard Payrastre, Sonia Severin
Journal: Blood
Blood (2017) 130 (18): 2032–2042.
https://doi.org/10.1182/blood-2017-04-781641
Published: 2017
Includes: Multimedia, Supplemental data
Journal Articles

Essential role of class II PI3K-C2α in platelet membrane morphology

Colin Valet, Gaëtan Chicanne, Childerick Severac, Claire Chaussade, Maria A. Whitehead, Cendrine Cabou, Marie-Pierre Gratacap, Frederique Gaits-Iacovoni, Bart Vanhaesebroeck, Bernard Payrastre, Sonia Severin
Journal: Blood
Blood (2015) 126 (9): 1128–1137.
https://doi.org/10.1182/blood-2015-03-636670
Published: 2015
Includes: Multimedia, Supplemental data
Journal Articles

Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate

Pierre-Alexandre Laurent, Sonia Séverin, Béatrice Hechler, Bart Vanhaesebroeck, Bernard Payrastre, Marie-Pierre Gratacap
Journal: Blood
Blood (2015) 125 (5): 881–888.
https://doi.org/10.1182/blood-2014-07-588335
Published: 2015
Includes: Multimedia, Supplemental data
Journal Articles

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

Catherine M. Hobbs, Harriet Manning, Cavan Bennett, Louella Vasquez, Sonia Severin, Lauren Brain, Alexandra Mazharian, Jose A. Guerrero, Juan Li, Nicole Soranzo, Anthony R. Green, Steve P. Watson, Cedric Ghevaert
Journal: Blood
Blood (2013) 122 (23): 3787–3797.
https://doi.org/10.1182/blood-2013-06-501452
Published: 2013
Includes: Supplemental data
Journal Articles

Physiological Levels of Jak2 V617F Result in Enhanced Megakaryocyte Differentiation, Proplatelet Formation and Platelet Reactivity.

Cedric J Ghevaert, MD, PhD, Juan Li, PhD, Sonia Severin, PhD, Jocelyn Auger, PhD, Steve Watson, BSc, PhD, Anthony R. Green, FRCP, FRCPath, FMed, Sci
Journal: Blood
Blood (2009) 114 (22): 226.
https://doi.org/10.1182/blood.V114.22.226.226
Published: 2009
Journal Articles

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion

Catherine Léon, Anita Eckly, Béatrice Hechler, Boris Aleil, Monique Freund, Catherine Ravanat, Marie Jourdain, Christelle Nonne, Josiane Weber, Ralph Tiedt, Marie-Pierre Gratacap, Sonia Severin, Jean-Pierre Cazenave, François Lanza, Radek Skoda, Christian Gachet
Journal: Blood
Blood (2007) 110 (9): 3183–3191.
https://doi.org/10.1182/blood-2007-03-080184
Published: 2007
Includes: Multimedia, Supplemental data
Journal Articles

Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLCγ2 activation

Ashraf Ragab, Sonia Séverin, Marie-Pierre Gratacap, Enrique Aguado, Marie Malissen, Martine Jandrot-Perrus, Bernard Malissen, Jeannie Ragab-Thomas, Bernard Payrastre
Journal: Blood
Blood (2007) 110 (7): 2466–2474.
https://doi.org/10.1182/blood-2007-02-075432
Published: 2007
Includes: Supplemental data