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Journal Articles

Pharmacokinetic-Guided Reduction of Emicizumab in Patients with Congenital Hemophilia a in the Netherlands: Interim Analysis from the Dosemi Study

Konrad Van Der Zwet, Marjon H. Cnossen, Floor CJI Moenen, Saskia EM Schols, Paula F Ypma, Paul L. den Exter, Louise Hooimeijer, Michiel Coppens, Ron A.A. Mathôt, Anouk A.M.T. Donners, Alexander Janssen, Ilmar Kruis, Eduard J. Van Beers, Corien L. Eckhardt, Rolf T. Urbanus, Lize Fie Ditteke Van Vulpen, Roger EG Schutgens, Kathelijn Fischer

Blood (2024) 144 (Supplement 1): 127.

https://doi.org/10.1182/blood-2024-193995

Published: 2024

Journal Articles

Evaluating the Clinical Relevance of Thrombin Generation Potential during Emicizumab Therapy

Konrad Van Der Zwet, Mark Roest, Dana Huskens, Eduard J. Van Beers, Kathelijn Fischer, Lize Fie Ditteke Van Vulpen, Roger EG Schutgens, Rolf T. Urbanus

Blood (2024) 144 (Supplement 1): 3960.

https://doi.org/10.1182/blood-2024-204587

Published: 2024

Journal Articles

Prothrombin forced into an awkward position

Rolf T. Urbanus

Blood (2024) 143 (19): 1888–1890.

https://doi.org/10.1182/blood.2024024240

Published: 2024

Journal Articles

Domain Specificity of Anti-Prothrombin Antibodies That Express Lupus Anticoagulant Activity

Rachel Gehlen, Tessa Noordermeer, Arne Vandevelde, Walid Chayoua, Marisa Ninivaggi, Romy De Laat-Kremers, Mark Roest, Philip G. De Groot, Katrien M.J. Devreese, Rolf T. Urbanus, Bas De Laat

Blood (2023) 142 (Supplement 1): 5529.

https://doi.org/10.1182/blood-2023-185610

Published: 2023

Journal Articles

Diversity of Plasmatic Thrombin Pools Regulate Thrombin Generation and Blood Clotting: Interference By a Novel Nanobody

Siyu Sun, Joke Konings, Rolf T. Urbanus, Dana Huskens, Frauke Swieringa, Romy De Laat-Kremers, Jinmi Zou, Philip G. De Groot, Mark Roest, Johan W. M. Heemskerk, Bas De Laat

Blood (2023) 142 (Supplement 1): 3978.

https://doi.org/10.1182/blood-2023-185665

Published: 2023

Journal Articles

Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis

Steven de Maat, Chantal C. Clark, Arjan D. Barendrecht, Simone Smits, Nadine D. van Kleef, Hinde El Otmani, Manon Waning, Marc van Moorsel, Michael Szardenings, Nicolas Delaroque, Kristof Vercruysse, Rolf T. Urbanus, Silvie Sebastian, Peter J. Lenting, Christoph Hagemeyer, Thomas Renné, Karen Vanhoorelbeke, Claudia Tersteeg, Coen Maas

Blood (2022) 139 (4): 597–607.

https://doi.org/10.1182/blood.2021011776

Published: 2022

Includes: Supplemental data

Journal Articles

Small Angle X-Ray Scattering Reveals the Conformation of Î² 2 glycoprotein I and the Conformational Binding Epitopes of Autoantibodies

Seung J. Kim, PhD, Jacob H. Rand, MD PhD, Philip G. de Groot, PhD, Rolf T. Urbanus, PhD, Dina Schneidman, PhD, Man K. Chan, PhD, Hilde Kelchtermans, PhD, Bas De Laat, MD PhD

Blood (2017) 130 (Supplement 1): 2378.

https://doi.org/10.1182/blood.V130.Suppl_1.2378.2378

Published: 2017

Journal Articles

The significance of autoantibodies against β 2 -glycoprotein I

Philip G. de Groot, Rolf T. Urbanus

Blood (2012) 120 (2): 266–274.

https://doi.org/10.1182/blood-2012-03-378646

Published: 2012

Journal Articles

β 2 -Glycoprotein I: a novel component of innate immunity

Çetin Ağar, Philip G. de Groot, Matthias Mörgelin, Stephanie D. D. C. Monk, Gwendolyn van Os, Johannes H. M. Levels, Bas de Laat, Rolf T. Urbanus, Heiko Herwald, Tom van der Poll, Joost C. M. Meijers

Blood (2011) 117 (25): 6939–6947.

https://doi.org/10.1182/blood-2010-12-325951

Published: 2011

Journal Articles

Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome

Zurina Romay-Penabad, Renan Aguilar-Valenzuela, Rolf T. Urbanus, Ronald H. W. M. Derksen, Maarten T. T. Pennings, Elizabeth Papalardo, Tuya Shilagard, Gracie Vargas, Yong Hwang, Philip G. de Groot, Silvia S. Pierangeli

Blood (2011) 117 (4): 1408–1414.

https://doi.org/10.1182/blood-2010-07-299099

Published: 2011

Journal Articles

β 2 -Glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome

Çetin Ağar, Gwendolyn M. A. van Os, Matthias Mörgelin, Richard R. Sprenger, J. Arnoud Marquart, Rolf T. Urbanus, Ronald H. W. M. Derksen, Joost C. M. Meijers, Philip G. de Groot

Blood (2010) 116 (8): 1336–1343.

https://doi.org/10.1182/blood-2009-12-260976

Published: 2010

Journal Articles

Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men

Bas de Laat, Philip G. de Groot, Ronald H. W. M. Derksen, Rolf T. Urbanus, Koen Mertens, Frits R. Rosendaal, Carine J. M. Doggen

Blood (2009) 114 (17): 3656–3661.

https://doi.org/10.1182/blood-2009-03-212910

Published: 2009

Journal Articles

Activation of the PI3K-Akt Pathway by Activated Protein C Occurs Via a Novel Receptor, Apolipoprotein E Receptor 2 (ApoER2)

Xia V. Yang, PhD, Yajnavalka Banerjee, PhD, Jose A. Fernandez, MD, PhD, Hiroshi Deguchi, MD, PhD, Xiao Xu, Laurent O. Mosnier, PhD, Rolf T Urbanus, MD, Phillip G deGroot, PhD, Tara C White, Owen J.T. McCarty, PhD, John H. Griffin, PhD

Blood (2008) 112 (11): 695.

https://doi.org/10.1182/blood.V112.11.695.695

Published: 2008

Journal Articles

Apolipoprotein E Receptor 2′ Mediates Pathogenic Effects of Dimeric β 2 glycoprotein I and of Anti- β 2 glycoprotein I Antibodies in Vivo

Zurina Romay-Penabad, Ph.D., Rolf T Urbanus, MD, Elizabeth Pappalardo, B.S., Yong Hwang, M.D., Ronald H.W.M. Derksen, MD., Tuya Shilagard, Ph.D., Gracie Vargas, Ph.D., Maarten TT Pennings, Ph.D., Philip G De Groot, PhD, Silvia S Pierangeli, Ph.D.

Blood (2008) 112 (11): 408.

https://doi.org/10.1182/blood.V112.11.408.408

Published: 2008

Journal Articles

Identification of a Role for Apolipoprotein E Receptor 2 as a Platelet Receptor for Factor XI

Tara C White, Michelle A Berny, Erik I Tucker, Jiaqing Pang, David Gailani, MD, Rolf T Urbanus, MD, Philip G de Groot, PhD, András Gruber, MD, Owen JT McCarty, PhD

Blood (2008) 112 (11): 3914.

https://doi.org/10.1182/blood.V112.11.3914.3914

Published: 2008

Journal Articles

Decreased beta2-Glycoprotein I Plasma Levels as a Risk Factor for Myocardial Infarction in Men.

Bas De Laat, PhD, Philip G. de Groot, PhD, Ronald H.W.M. Derksen, MD., Rolf T. Urbanus, Koen Mertens, PhD, Frits Rosendaal, MD, PhD, Carine J.M. Doggen, PhD

Blood (2008) 112 (11): 1813.

https://doi.org/10.1182/blood.V112.11.1813.1813

Published: 2008

Journal Articles

IgG antibodies that recognize epitope Gly40-Arg43 in domain I of β 2 –glycoprotein I cause LAC, and their presence correlates strongly with thrombosis

Bas de Laat, Ronald H. W. M. Derksen, Rolf T. Urbanus, Philip G. de Groot

Blood (2005) 105 (4): 1540–1545.

https://doi.org/10.1182/blood-2004-09-3387

Published: 2005

Journal Articles

β 2 -glycoprotein I–dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome

H. Bas de Laat, Ronald H.W.M. Derksen, Rolf T. Urbanus, Mark Roest, Philip G. de Groot

Blood (2004) 104 (12): 3598–3602.

https://doi.org/10.1182/blood-2004-03-1107

Published: 2004

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Pharmacokinetic-Guided Reduction of Emicizumab in Patients with Congenital Hemophilia a in the Netherlands: Interim Analysis from the Dosemi Study

Evaluating the Clinical Relevance of Thrombin Generation Potential during Emicizumab Therapy

Prothrombin forced into an awkward position

Domain Specificity of Anti-Prothrombin Antibodies That Express Lupus Anticoagulant Activity

Diversity of Plasmatic Thrombin Pools Regulate Thrombin Generation and Blood Clotting: Interference By a Novel Nanobody

Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis

Small Angle X-Ray Scattering Reveals the Conformation of Î² 2 glycoprotein I and the Conformational Binding Epitopes of Autoantibodies

The significance of autoantibodies against β 2 -glycoprotein I

β 2 -Glycoprotein I: a novel component of innate immunity

Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome

β 2 -Glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome

Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men

Activation of the PI3K-Akt Pathway by Activated Protein C Occurs Via a Novel Receptor, Apolipoprotein E Receptor 2 (ApoER2)

Apolipoprotein E Receptor 2′ Mediates Pathogenic Effects of Dimeric β 2 glycoprotein I and of Anti- β 2 glycoprotein I Antibodies in Vivo

Identification of a Role for Apolipoprotein E Receptor 2 as a Platelet Receptor for Factor XI

Decreased beta2-Glycoprotein I Plasma Levels as a Risk Factor for Myocardial Infarction in Men.

IgG antibodies that recognize epitope Gly40-Arg43 in domain I of β 2 –glycoprotein I cause LAC, and their presence correlates strongly with thrombosis

β 2 -glycoprotein I–dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome

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