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Journal Articles

A Short Thrombin Generation Time-to-Peak/Lag Time Ratio Is an Independent Risk Factor for Mortality in the General Population

Romy De Laat-Kremers, Simona Costanzo, Mark Roest, Amalia de Curtis, Dana Huskens, Augusto Di Castelnuovo, Marisa Ninivaggi, Chiara Cerletti, Maria Benedetta Donati, Bas De Laat, Licia Iacoviello

Blood (2023) 142 (Supplement 1): 3989.

https://doi.org/10.1182/blood-2023-189881

Published: 2023

Journal Articles

The Variable Heavy Chain Antibody Syn-VWFA1 Inhibits the Interaction of Platelets to Von Willebrand Factor in Solution but Not to Immobilized Von Willebrand Factor Thereby Inhibiting 3-Dimensional but Not 2-Dimensional Thrombus Formation

Dana Huskens, Lisa Nynke Van Der Vorm, Joke Konings, Nicholas Arce, Mark Roest, Philip G. De Groot, Renhao Li, Jasper A. Remijn, Bas De Laat

Blood (2023) 142 (Supplement 1): 1193.

https://doi.org/10.1182/blood-2023-177887

Published: 2023

Journal Articles

Diversity of Plasmatic Thrombin Pools Regulate Thrombin Generation and Blood Clotting: Interference By a Novel Nanobody

Siyu Sun, Joke Konings, Rolf T. Urbanus, Dana Huskens, Frauke Swieringa, Romy De Laat-Kremers, Jinmi Zou, Philip G. De Groot, Mark Roest, Johan W. M. Heemskerk, Bas De Laat

Blood (2023) 142 (Supplement 1): 3978.

https://doi.org/10.1182/blood-2023-185665

Published: 2023

Journal Articles

A Novel Plasminogen Activator Anti-Fibrin-uPA Increases the Sensitivity of the Plasmin Generation Assay to Therapeutic Target PAI-1

Ilaria De Simone, Mark Roest, Alisa S Wolberg, Bas de Laat, Dana Huskens

Blood (2023) 142 (Supplement 1): 5464.

https://doi.org/10.1182/blood-2023-181509

Published: 2023

Journal Articles

Domain Specificity of Anti-Prothrombin Antibodies That Express Lupus Anticoagulant Activity

Rachel Gehlen, Tessa Noordermeer, Arne Vandevelde, Walid Chayoua, Marisa Ninivaggi, Romy De Laat-Kremers, Mark Roest, Philip G. De Groot, Katrien M.J. Devreese, Rolf T. Urbanus, Bas De Laat

Blood (2023) 142 (Supplement 1): 5529.

https://doi.org/10.1182/blood-2023-185610

Published: 2023

Journal Articles

Prediction of Venous Thromboembolism in Patients with Cancer Using Neural Network

Romy De Laat-Kremers, Scott Tagawa, Madeline Young, Christine Garcia, Manish Shah, Pashtoon Murtaza Kasi, Jacob H Rand, Bas De Laat, Maria T DeSancho

Blood (2023) 142 (Supplement 1): 1235.

https://doi.org/10.1182/blood-2023-184990

Published: 2023

Journal Articles

Measuring Thrombin Generation in Platelet Rich Plasma with the ST Genesia

Marisa Ninivaggi, Romy De Laat-Kremers, Bas De Laat

Blood (2023) 142 (Supplement 1): 5470.

https://doi.org/10.1182/blood-2023-178662

Published: 2023

Journal Articles

Cellular Components in Whole Blood Contribute to the Development of Thromboembolic Events in Patients with Pancreatic Cancer

Ruth A.L. Willems, Mark Roest, Judith de Vos-Geelen, Bas de Laat, Hugo Ten Cate

Blood (2023) 142 (Supplement 1): 1286.

https://doi.org/10.1182/blood-2023-185655

Published: 2023

Journal Articles

Hemostasis Biomarkers and Long-Term Risk of Recurrent Cardiovascular Events and Bleeding Complications in Young Patients with an Ischemic Stroke

Janneke Spiegelenberg, Mark Roest, Bas De Laat, Marleen van Gelder, Saskia Middeldorp, Anil Tuladhar, Jenneke Leentjens, Frank-Erik De Leeuw

Blood (2023) 142 (Supplement 1): 2645.

https://doi.org/10.1182/blood-2023-187152

Published: 2023

Journal Articles

Intermediate Results of the Cornell Blood Coagulation in Cancer Study (COBLOCA-Study)

Romy de Laat-Kremers, Marina Loizou, Scott Tawaga, Jacob H. Rand, Bas de Laat, Maria T DeSancho

Blood (2022) 140 (Supplement 1): 5666–5667.

https://doi.org/10.1182/blood-2022-163240

Published: 2022

Journal Articles

Neural Network Diagnoses the Antiphospholipid Syndrome without Interrupting Anticoagulant Therapy

Romy de Laat-Kremers, Denis Wahl, Stéphane Zuily, Marisa Ninivaggi, Veronique Regnault, Jacek Musial, Philip G. de Groot, Katrien Devreese, Bas de Laat

Blood (2022) 140 (Supplement 1): 8388–8390.

https://doi.org/10.1182/blood-2022-163181

Published: 2022

Journal Articles

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Adam Miszta, Anna K. Kopec, Asmita Pant, Lori A. Holle, James R. Byrnes, Daniel A. Lawrence, Kirk C. Hansen, Matthew J. Flick, James P. Luyendyk, Bas de Laat, Alisa S. Wolberg

Blood (2020) 135 (19): 1704–1717.

https://doi.org/10.1182/blood.2019004267

Published: 2020

Includes: Supplemental data

Journal Articles

Platelet-Derived Microvesicles Reverse the Lupus Anticoagulant Effect and Are More Potent then Synthetic Phospholipids in Supporting Thrombin Generation in Antiphospholipid Syndrome

Cuicui Bai, PhD, Saartje Bloemen, PhD, Xiao Xuan Wu, MD, Ruchika Goel, MD MPH, Sheshadri Narayanan, Bas De Laat, MD, PhD, Jacob H. Rand, MD PhD, Ljiljana V. Vasovic, MD

Blood (2018) 132 (Supplement 1): 3790.

https://doi.org/10.1182/blood-2018-99-113486

Published: 2018

Journal Articles

Development of a Neural Network to Predict Thrombosis in the Antiphospholipid Syndrome with an Accuracy of 87%

Romy Kremers, PhD, Stéphane Zuily, MD PhD, Philip De Groot, PhD, Coenraad Hemker, MD PhD, Denis Wahl, MD PhD, Bas De Laat, MD, PhD

Blood (2018) 132 (Supplement 1): 3796.

https://doi.org/10.1182/blood-2018-99-115834

Published: 2018

Journal Articles

Active and Ultra-Large Von Willebrand Factor Is Significantly Elevated in Patients with Immune Thrombotic Thrombocytopenic Purpura

Wenjing Cao, PhD, Alicia Veninga, M.Sc., Elizabeth M. Staley, MD, PhD, Adam Miszta, PhD, Nicole Kocher, B.Sc., Lance Williams, III, MD, Marisa B. Marques, MD, Bas de Laat, MD, PhD, X. Long Zheng, MD PhD

Blood (2018) 132 (Supplement 1): 523.

https://doi.org/10.1182/blood-2018-99-117647

Published: 2018

Journal Articles

Flow Cytometric Analysis of Platelet Function in Patients on Antiplatelet Therapy and Suspected Thrombocytopathy

Dana Huskens, PhD, Mark Roest, PhD, Lisa Florin, Bas De Laat, MD, PhD, Katrien Devreese, PhD MD

Blood (2018) 132 (Supplement 1): 1161.

https://doi.org/10.1182/blood-2018-99-110295

Published: 2018

Journal Articles

The Isotype of Antiphospholipid Antibodies and Their Associated Risk on Thrombosis and Pregnancy Morbidity; What Are the Odds?

Walid Chayouâ, MSc, Hilde Kelchtermans, PhD, Gary Moore, MD, Jean-Christophe Gris, MD PhD, Jacek Musial, MD PhD, Stéphane Zuily, MDPhD, Bas De Laat, MD, PhD, Katrien Devreese, PhD MD

Blood (2018) 132 (Supplement 1): 1220.

https://doi.org/10.1182/blood-2018-99-113361

Published: 2018

Journal Articles

Small Angle X-Ray Scattering Reveals the Conformation of Î² 2 glycoprotein I and the Conformational Binding Epitopes of Autoantibodies

Seung J. Kim, PhD, Jacob H. Rand, MD PhD, Philip G. de Groot, PhD, Rolf T. Urbanus, PhD, Dina Schneidman, PhD, Man K. Chan, PhD, Hilde Kelchtermans, PhD, Bas De Laat, MD PhD

Blood (2017) 130 (Supplement 1): 2378.

https://doi.org/10.1182/blood.V130.Suppl_1.2378.2378

Published: 2017

Journal Articles

Applying Neural Networking Identifies Antiphospholipid Syndrome Patients with an Accuracy of 98.7%

Romy Kremers, PhD, Stéphane Zuily, MDPhD, Hilde Kelchtermans, PhD, Philip G. de Groot, PhD, Tessa Peters, Saartje Bloemen, PhD, Coenraad Hemker, MD PhD, Denis Wahl, MD PhD, Bas De Laat, MD PhD

Blood (2017) 130 (Supplement 1): 460.

https://doi.org/10.1182/blood.V130.Suppl_1.460.460

Published: 2017

Journal Articles

Poor Agreement between Commercially Available Anti-Cardiolipin and Anti-β2glycoprotein I IgG and IgM Solid Phase Assays Hampers Uniformity in the Classification of Antiphospholipid Syndrome Patients

Walid Chayouâ, MSc, Hilde Kelchtermans, PhD, Gary Moore, MD, Jean-Christophe Gris, MD PhD, Jacek Musial, MD PhD, Denis Wahl, MD PhD, Stéphane Zuily, MDPhD, Armando Tripodi, PhD, Pierre Fontana, MD PhD, Jasper A. Remijn, PhD, Bas De Laat, MD PhD, Katrien Devreese, MD PhD

Blood (2017) 130 (Supplement 1): 1059.

https://doi.org/10.1182/blood.V130.Suppl_1.1059.1059

Published: 2017

NARROW

A Short Thrombin Generation Time-to-Peak/Lag Time Ratio Is an Independent Risk Factor for Mortality in the General Population

The Variable Heavy Chain Antibody Syn-VWFA1 Inhibits the Interaction of Platelets to Von Willebrand Factor in Solution but Not to Immobilized Von Willebrand Factor Thereby Inhibiting 3-Dimensional but Not 2-Dimensional Thrombus Formation

Diversity of Plasmatic Thrombin Pools Regulate Thrombin Generation and Blood Clotting: Interference By a Novel Nanobody

A Novel Plasminogen Activator Anti-Fibrin-uPA Increases the Sensitivity of the Plasmin Generation Assay to Therapeutic Target PAI-1

Domain Specificity of Anti-Prothrombin Antibodies That Express Lupus Anticoagulant Activity

Prediction of Venous Thromboembolism in Patients with Cancer Using Neural Network

Measuring Thrombin Generation in Platelet Rich Plasma with the ST Genesia

Cellular Components in Whole Blood Contribute to the Development of Thromboembolic Events in Patients with Pancreatic Cancer

Hemostasis Biomarkers and Long-Term Risk of Recurrent Cardiovascular Events and Bleeding Complications in Young Patients with an Ischemic Stroke

Intermediate Results of the Cornell Blood Coagulation in Cancer Study (COBLOCA-Study)

Neural Network Diagnoses the Antiphospholipid Syndrome without Interrupting Anticoagulant Therapy

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Platelet-Derived Microvesicles Reverse the Lupus Anticoagulant Effect and Are More Potent then Synthetic Phospholipids in Supporting Thrombin Generation in Antiphospholipid Syndrome

Development of a Neural Network to Predict Thrombosis in the Antiphospholipid Syndrome with an Accuracy of 87%

Active and Ultra-Large Von Willebrand Factor Is Significantly Elevated in Patients with Immune Thrombotic Thrombocytopenic Purpura

Flow Cytometric Analysis of Platelet Function in Patients on Antiplatelet Therapy and Suspected Thrombocytopathy

The Isotype of Antiphospholipid Antibodies and Their Associated Risk on Thrombosis and Pregnancy Morbidity; What Are the Odds?

Small Angle X-Ray Scattering Reveals the Conformation of Î² 2 glycoprotein I and the Conformational Binding Epitopes of Autoantibodies

Applying Neural Networking Identifies Antiphospholipid Syndrome Patients with an Accuracy of 98.7%

Poor Agreement between Commercially Available Anti-Cardiolipin and Anti-β2glycoprotein I IgG and IgM Solid Phase Assays Hampers Uniformity in the Classification of Antiphospholipid Syndrome Patients

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American Society of Hematology

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ASH Publications

American Society of Hematology

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