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The Variable Heavy Chain Antibody Syn-VWFA1 Inhibits the Interaction of Platelets to Von Willebrand Factor in Solution but Not to Immobilized Von Willebrand Factor Thereby Inhibiting 3-Dimensional but Not 2-Dimensional Thrombus Formation

Dana Huskens, Lisa Nynke Van Der Vorm, Joke Konings, Nicholas Arce, Mark Roest, Philip G. De Groot, Renhao Li, Jasper A. Remijn, Bas De Laat
Journal: Blood
Blood (2023) 142 (Supplement 1): 1193.
https://doi.org/10.1182/blood-2023-177887
Published: 2023
Journal Articles

Diversity of Plasmatic Thrombin Pools Regulate Thrombin Generation and Blood Clotting: Interference By a Novel Nanobody

Siyu Sun, Joke Konings, Rolf T. Urbanus, Dana Huskens, Frauke Swieringa, Romy De Laat-Kremers, Jinmi Zou, Philip G. De Groot, Mark Roest, Johan W. M. Heemskerk, Bas De Laat
Journal: Blood
Blood (2023) 142 (Supplement 1): 3978.
https://doi.org/10.1182/blood-2023-185665
Published: 2023
Journal Articles

Hypobaric Hypoxia Induces Hypercoagulability Due to an Increase in Microparticles

Cécile H. Kicken, MD, Marisa Ninivaggi, PhD, Joke Konings, PhD, Martijn Moorlag, MSc, Leslie In het Panhuis, Marcus D. Lancé, MD PhD, Bas De Laat, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3549.
https://doi.org/10.1182/blood.V126.23.3549.3549
Published: 2015
Journal Articles

Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin

Joke Konings, José W. P. Govers-Riemslag, Helen Philippou, Nicola J. Mutch, Julian I. Borissoff, Peter Allan, Sumitra Mohan, Guido Tans, Hugo ten Cate, Robert A. S. Ariëns
Journal: Blood
Blood (2011) 118 (14): 3942–3951.
https://doi.org/10.1182/blood-2011-03-339572
Published: 2011
Includes: Supplemental data