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Journal Articles

Antimyeloma activity of heat shock protein-90 inhibition

Constantine S. Mitsiades, Nicholas S. Mitsiades, Ciaran J. McMullan, Vassiliki Poulaki, Andrew L. Kung, Faith E. Davies, Gareth Morgan, Masaharu Akiyama, Reshma Shringarpure, Nikhil C. Munshi, Paul G. Richardson, Teru Hideshima, Dharminder Chauhan, Xuesong Gu, Charles Bailey, Marie Joseph, Towia A. Libermann, Neal S. Rosen, Kenneth C. Anderson

Blood (2006) 107 (3): 1092–1100.

https://doi.org/10.1182/blood-2005-03-1158

Published: 2006

Includes: Supplemental data

Journal Articles

The JAK Inhibitor INCB20 Induces Antiproliferative and Apoptotic Effects in Human Myeloma Cells In Vitro and In Vivo .

Renate Burger, PhD, Steven Legouill, MD, Yu-Tzu Tai, PhD, Reshma Shringarpure, PhD, Klaus Podar, MD, PhD, Laurence Catley, MD, Pierfrancesco Tassone, MD, Paola Neri, MD, Teru Hideshima, MD, Dharminder Chauhan, PhD, Eian Caulder, BS, Kris Vaddi, PhD, Claire L. Neilan, PhD, Martin Gramatzki, MD, Jordan S. Fridman, PhD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 3357.

https://doi.org/10.1182/blood.V106.11.3357.3357

Published: 2005

Journal Articles

Cytotoxic activity of the maytansinoid immunoconjugate B-B4–DM1 against CD138 + multiple myeloma cells

Pierfrancesco Tassone, Victor S. Goldmacher, Paola Neri, Antonella Gozzini, Masood A. Shammas, Kathleen R. Whiteman, Linda L. Hylander-Gans, Daniel R. Carrasco, Teru Hideshima, Reshma Shringarpure, Jialan Shi, Charles K. Allam, John Wijdenes, Salvatore Venuta, Nikhil C. Munshi, Kenneth C. Anderson

Blood (2004) 104 (12): 3688–3696.

https://doi.org/10.1182/blood-2004-03-0963

Published: 2004

Journal Articles

Lymphoplasmacytic Cells and Mast Cells Are Targets for Imatinib Mesylate (Gleevec, Glivec) in Waldenstrom’s Macroglobulinemia.

Olivier Tournilhac, Daniel Ditzel Santos, Lian Xu, Evdoxia Hatjiharissi, Yu Tsu, Tai, Laurie Catley, Zachary Hunter, Andrew Branagan, Renate Burger, Reshma Shringarpure, Joshua Boyce, Kenneth C. Anderson, Steven P. Treon

Blood (2004) 104 (11): 4929.

https://doi.org/10.1182/blood.V104.11.4929.4929

Published: 2004

Journal Articles

Caveolin-1 Is Required for VEGF- Triggered Multiple Myeloma Cell Migration and Is Targeted by Bortezomib (Velcade®).

Klaus Podar, MD, PhD, Reshma Shringarpure, PhD, Yu-Tzu Tai, PhD, Melissa Simoncini, BS, Martin Sattler, PhD, Kenji Ishitsuka, MD, PhD, Paul G. Richardson, MD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Anderson C. Kenneth, MD

Blood (2004) 104 (11): 2453.

https://doi.org/10.1182/blood.V104.11.2453.2453

Published: 2004

Journal Articles

Increased TCF-4 Expression Correlates with Reduced Caspase-3 Induction and Confers Resistance to Bortezomib.

Reshma Shringarpure, PhD, Deepak Bhole, PhD, Renate Burger, PhD, Laurence Catley, MBBS, FRACP, FRCPA, Klaus Podar, MD, PhD, Yu-Tzu Tai, PhD, Teru Hideshima, MD, PhD, Constantine Mitsiades, MD, PhD, Nikhil C. Munshi, MD, Dharminder Chauhan, PhD, Kenneth C. Anderson, PhD

Blood (2004) 104 (11): 285.

https://doi.org/10.1182/blood.V104.11.285.285

Published: 2004

Journal Articles

JNK Activation and Fas Up-Regulation Precede Proteasomal Degradation of Topoisomerase I in SN38-Mediated Cytotoxicity Against Multiple Myeloma.

Laurence Catley, MBBS, FRACP, FRCPA, Yu-Tzu Tai, PhD, Reshma Shringarpure, PhD, Renate Burger, PhD, Moni Son, Klaus Podar, MD, PhD, Dharminder Chauhan, PhD, Teru Hideshima, MD, PhD, Louis Denis, MD, Paul G. Richardson, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD

Blood (2004) 104 (11): 3413.

https://doi.org/10.1182/blood.V104.11.3413.3413

Published: 2004

Journal Articles

NVP-AEW541: A Selective Small Molecule IGF-1R Tyrosine Kinase Inhibitor Is Active Against Multiple Myeloma and Other Hematologic Neoplasias and Solid Tumors.

Nicholas Mitsiades, MD, PhD, Ciaran J. McMullan, Vassiliki Poulaki, MD, PhD, Reshma Shringarpure, PhD, Towia A. Libermann, PhD, Teru Hideshima, MD, PhD, Dharminder Chauhan, PhD, Robert L. Schlossman, MD, Paul G. Richardson, MD, Nikhil C. Munshi, MD, PhD, Carlos Garcia-Echeverria, PhD, Francesco Hoffmann, PhD, Kenneth C. Anderson, MD, Constantine S. Mitsiades, MD, PhD

Blood (2004) 104 (11): 766.

https://doi.org/10.1182/blood.V104.11.766.766

Published: 2004

Journal Articles

Inhibition of Human Plasmacytoma Cell Growth by a Novel JAK Kinase Inhibitor.

Blood (2004) 104 (11): 644.

https://doi.org/10.1182/blood.V104.11.644.644

Published: 2004

Journal Articles

GW654652, the pan-inhibitor of VEGF receptors, blocks the growth and migration of multiple myeloma cells in the bone marrow microenvironment

Klaus Podar, Laurence P. Catley, Yu-Tzu Tai, Reshma Shringarpure, Pedro Carvalho, Toshiaki Hayashi, Renate Burger, Robert L. Schlossman, Paul G. Richardson, Lini N. Pandite, Rakesh Kumar, Teru Hideshima, Dharminder Chauhan, Kenneth C. Anderson

Blood (2004) 103 (9): 3474–3479.

https://doi.org/10.1182/blood-2003-10-3527

Published: 2004

Journal Articles

The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti–multiple myeloma (MM) activity and overcome bortezomib resistance

Dharminder Chauhan, Guilan Li, Klaus Podar, Teru Hideshima, Reshma Shringarpure, Laurence Catley, Constantine Mitsiades, Nikhil Munshi, Yu Tzu Tai, Nanjoo Suh, Gordon W. Gribble, Tadashi Honda, Robert Schlossman, Paul Richardson, Michael B. Sporn, Kenneth C. Anderson

Blood (2004) 103 (8): 3158–3166.

https://doi.org/10.1182/blood-2003-08-2873

Published: 2004

Journal Articles

Immunomodulatory drug costimulates T cells via the B7-CD28 pathway

Richard LeBlanc, Teru Hideshima, Laurence P. Catley, Reshma Shringarpure, Renate Burger, Nicholas Mitsiades, Constantine Mitsiades, Puneet Cheema, Dharminder Chauhan, Paul G. Richardson, Kenneth C. Anderson, Nikhil C. Munshi

Blood (2004) 103 (5): 1787–1790.

https://doi.org/10.1182/blood-2003-02-0361

Published: 2004

Journal Articles

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

Dharminder Chauhan, Guilan Li, Teru Hideshima, Klaus Podar, Constantine Mitsiades, Nicholas Mitsiades, Laurence Catley, Yu Tzu Tai, Toshiaki Hayashi, Reshma Shringarpure, Renate Burger, Nikhil Munshi, Yasuyuki Ohtake, Satya Saxena, Kenneth C. Anderson

Blood (2003) 102 (9): 3379–3386.

https://doi.org/10.1182/blood-2003-05-1417

Published: 2003

Journal Articles

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

Laurence Catley, Ellen Weisberg, Yu-Tzu Tai, Peter Atadja, Stacy Remiszewski, Teru Hideshima, Nicholas Mitsiades, Reshma Shringarpure, Richard LeBlanc, Dharminder Chauhan, Nikhil C. Munshi, Robert Schlossman, Paul Richardson, James Griffin, Kenneth C. Anderson

Blood (2003) 102 (7): 2615–2622.

https://doi.org/10.1182/blood-2003-01-0233

Published: 2003

NARROW

Antimyeloma activity of heat shock protein-90 inhibition

The JAK Inhibitor INCB20 Induces Antiproliferative and Apoptotic Effects in Human Myeloma Cells In Vitro and In Vivo .

Cytotoxic activity of the maytansinoid immunoconjugate B-B4–DM1 against CD138 + multiple myeloma cells

Lymphoplasmacytic Cells and Mast Cells Are Targets for Imatinib Mesylate (Gleevec, Glivec) in Waldenstrom’s Macroglobulinemia.

Caveolin-1 Is Required for VEGF- Triggered Multiple Myeloma Cell Migration and Is Targeted by Bortezomib (Velcade®).

Increased TCF-4 Expression Correlates with Reduced Caspase-3 Induction and Confers Resistance to Bortezomib.

JNK Activation and Fas Up-Regulation Precede Proteasomal Degradation of Topoisomerase I in SN38-Mediated Cytotoxicity Against Multiple Myeloma.

NVP-AEW541: A Selective Small Molecule IGF-1R Tyrosine Kinase Inhibitor Is Active Against Multiple Myeloma and Other Hematologic Neoplasias and Solid Tumors.

Inhibition of Human Plasmacytoma Cell Growth by a Novel JAK Kinase Inhibitor.

GW654652, the pan-inhibitor of VEGF receptors, blocks the growth and migration of multiple myeloma cells in the bone marrow microenvironment

The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti–multiple myeloma (MM) activity and overcome bortezomib resistance

Immunomodulatory drug costimulates T cells via the B7-CD28 pathway

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

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American Society of Hematology

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American Society of Hematology

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