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Journal Articles

Polatuzumab Vedotin in Relapsed and Refractory (r/r) Large B-Cell Lymphoma (LBCL): Real-World Data of the German National Compassionate Use Program (CUP)

Blood (2020) 136 (Supplement 1): 11–13.

https://doi.org/10.1182/blood-2020-136539

Published: 2020

Journal Articles

Elevated Pre-Treatment Fetal Hemoglobin Predicts Better Outcome in MDS/AML Patients Receiving 5-Aza-2'-Deoxycytidine (DAC)

Rainer Claus, MD, Gabriele Ihorst, PhD, Philipp Sander, Ljudmila Bogatyreva, Heiko Becker, MD, Pierre W Wijermans, MD, Stefan Suciu, Emmanuel Bissé, MD PhD, Michael Lübbert, MD

Blood (2016) 128 (22): 3175.

https://doi.org/10.1182/blood.V128.22.3175.3175

Published: 2016

Journal Articles

Implementation of a Molecular Tumor Board in Clinical Decision Making at the Medical Center University of Freiburg

Blood (2016) 128 (22): 3579.

https://doi.org/10.1182/blood.V128.22.3579.3579

Published: 2016

Journal Articles

The Pan-PIM Kinase Inhibitor LGB321 Affects Apoptotic Pathways and Microenvironmental Interactions in CLL

Sarah Decker, PhD, Sandra Kissel, Konrad Aumann, MD, Thorsten Zenz, Katja Zirlik, MD, Rainer Claus, MD, Justus Duyster, MD, Christine Dierks, MD

Blood (2016) 128 (22): 4370.

https://doi.org/10.1182/blood.V128.22.4370.4370

Published: 2016

Journal Articles

Decitabine (DAC) in Combination with Donor Lymphocyte Infusions (DLIs) Can Induce Remissions of Overt Aml Relapses after Allogeneic Transplantation

Sebastian Sommer, MD, Rainer Claus, MD, Hartmut Bertz, MD, Ralph Wäsch, MD, Reinhard Marks, MD, Robert Zeiser, MD, Ljudmila Bogatyrova, Jürgen Finke, MD, Michael Lübbert, MD

Blood (2016) 128 (22): 2247.

https://doi.org/10.1182/blood.V128.22.2247.2247

Published: 2016

Journal Articles

SYK Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia

Marco Benkisser-Petersen, Maike Buchner, Arlette Dörffel, Marcus Dühren von Minden, Kerstin Leberecht, Kathrin Kläsener, Rainer Claus, MD, Ariane Ott, Christine Dierks, Hassan Jumaa, Fabio Malavasi, Michael Reth, Hendrik Veelken, Katja Zirlik, MD

Blood (2015) 126 (23): 2910.

https://doi.org/10.1182/blood.V126.23.2910.2910

Published: 2015

Journal Articles

Combined Inhibition of BCR and IGF1R Signaling Leads to Synergistic Apoptosis Induction in Primary CLL Cells in Vitro

Charlotte Schmidt-Salzmann, MD, Niuscha Yaktapour, PhD, Tilman Brummer, PhD, Katja Zirlik, MD, Rainer Claus, MD

Blood (2015) 126 (23): 4168.

https://doi.org/10.1182/blood.V126.23.4168.4168

Published: 2015

Journal Articles

Single Cell Genotyping of Inv(16) AML in CBL Mutated Clonal Hematopoiesis Characterizes Clonal Architecture and Evolution of Exome Sequencing-Identified Mutations in the Protein Tyrosine Phosphatase Ptprt and Other Genes

Christoph Niemöller, Sabine Bleul, Nadja Blagitko-Dorfs, PhD, Christine Greil, MD, Kenichi Yoshida, MD PhD, Rainer Claus, MD, Dietmar Pfeifer, PhD, Seishi Ogawa, MD PhD, Michael Lübbert, MD, Heiko Becker, MD

Blood (2015) 126 (23): 3834.

https://doi.org/10.1182/blood.V126.23.3834.3834

Published: 2015

Journal Articles

Induction of an Erythroid but Not Megakaryocytic Expression Signature in Myeloid Cells By in Vitro 5-Aza-2'-Deoxycytidine Treatment

Rainer Claus, MD, Philipp Sander, Dietmar Pfeifer, PhD, Lioudmila Bogatyreva, Emmanuel Bissé, MDPhD, Michael Lübbert, MDPhD

Blood (2015) 126 (23): 4538.

https://doi.org/10.1182/blood.V126.23.4538.4538

Published: 2015

Journal Articles

ABCB1 Expression in Acute Myeloid Leukemia (AML): A Possible Predictive Value for Treatment Resistance?

Stephany Corrêa, PhD, Eliana Abdelhay, PhD, Peter Paschka, MD, Verena I. Gaidzik, MD, Rocio Hassan, PhD, Rainer Claus, MD, Richard F. Schlenk, MD, Konstanze Döhner, MD, Lars Bullinger, MD PhD

Blood (2014) 124 (21): 3618.

https://doi.org/10.1182/blood.V124.21.3618.3618

Published: 2014

Journal Articles

In Vivo Methylome Changes in Purified Peripheral Blood Blasts and T Cells of AML Patients Treated with Decitabine: Statistical Modelling of a Hypomethylation Response

Blood (2014) 124 (21): 870.

https://doi.org/10.1182/blood.V124.21.870.870

Published: 2014

Journal Articles

NFATc1 Is Transcriptionally Activated in Chronic Lymphocytic Leukemia (CLL) By Promotor DNA-Hypomethylation Which Correlates with in-Vitro Vulnerability to Calcineurin Inhibitors

Christine Wolf, Katharina Filarsky, Angela Garding, PhD, Rainer Claus, MD, Christopher C Oakes, PhD, Irina Idler, PhD, Christoph Plass, PhD, Peter Lichter, PhD, Hartmut Doehner, MD, Stephan Stilgenbauer, MD, Daniel Mertens, PhD

Blood (2014) 124 (21): 1941.

https://doi.org/10.1182/blood.V124.21.1941.1941

Published: 2014

Journal Articles

Differential DNA Methylation Predicts Response To Combined Treatment Regimens With a DNA Methyltransferase Inhibitor In Acute Myeloid Leukemia (AML)

Maximilian Schmutz, Manuela Zucknick, PhD, Richard F. Schlenk, MD, Konstanze Döhner, MD, Hartmut Döhner, MD, Christoph Plass, PhD, Lars Bullinger, MD, PhD, Rainer Claus, MD

Blood (2013) 122 (21): 2539.

https://doi.org/10.1182/blood.V122.21.2539.2539

Published: 2013

Journal Articles

Decitabine Response Associated Gene Expression Patterns In Acute Myeloid Leukemia (AML)

Stephan R Bohl, MD, Rainer Claus, MD, Anna Dolnik, Richard F. Schlenk, MD, Konstanze Döhner, MD, Björn Hackanson, MD, Hartmut Döhner, MD, Michael Lübbert, MD, Lars Bullinger, MD, PhD

Blood (2013) 122 (21): 3756.

https://doi.org/10.1182/blood.V122.21.3756.3756

Published: 2013

Journal Articles

Heterogeneity and Evolution Of DNA Methylation In Chronic Lymphocytic Leukemia

Christopher C Oakes, Ph.D, Rainer Claus, MD, Lei Gu, Yassen Assenov, Jennifer Hüllein, Manuela Zucknick, David Brocks, Olga Bogatyrova, Christopher R. Schmidt, Laura Rassenti, PhD, Thomas J. Kipps, MD, PhD, Daniel Mertens, PhD, Peter Lichter, PhD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD, John C. Byrd, MD, Thorsten Zenz, MD, Christoph Plass, PhD

Blood (2013) 122 (21): 1626.

https://doi.org/10.1182/blood.V122.21.1626.1626

Published: 2013

Journal Articles

A Complex Molecular Network Controls Palmitoylation-Dependant CD95 Sensitivity Of CLL Cells

Valeska Berg, Nachiket Vartak, PhD, Rainer Claus, MD, Julia Claasen, Marion Rusch, PhD, Christian P. Pallasch, MD, Herbert Waldmann, PhD, Christopher Plass, PhD, Philippe Bastiaens, PhD, Michael Hallek, MD, Christian Hedberg, PhD, Clemens Wendtner, MD, Lukas P. Frenzel, MD

Blood (2013) 122 (21): 4148.

https://doi.org/10.1182/blood.V122.21.4148.4148

Published: 2013

Journal Articles

The Hsp90 Inhibitor 17-DMAG Increases SOCS3 and Regulates Cytokine Production, Migration and Cell Death in Chronic Lymphocytic Leukemia

Erin K Hertlein, PhD, Timothy L. Chen, Rainer Claus, MD, Christoph Plass, PhD, Amy Lehman, David Jarjoura, PhD, Kami Maddocks, MD, Jeffrey A. Jones, MD, MPH, David M. Lucas, PhD, Amy J. Johnson, PhD, John C. Byrd, MD

Blood (2012) 120 (21): 1362.

https://doi.org/10.1182/blood.V120.21.1362.1362

Published: 2012

Journal Articles

Aberrant Epigenetic Suppression of the Ptprot Gene Encoding a Protein Tyrosine Phosphatase Targeting KIT in Acute Myeloid Leukemia

Tasneem Motiwala, PhD, Satavisha Roy, Shujun Liu, Ph.D, Sebastian Schwind, MD, Rainer Claus, MD, Xiaokui Mo, PhD, Ramiro Garzon, MD, Hartmut Dohner, MD, Konstanze Dohner, MD, PhD, David Jarjoura, PhD, Christoph Plass, PhD, Guido Marcucci, MD, Samson T. Jacob, PhD

Blood (2012) 120 (21): 1322.

https://doi.org/10.1182/blood.V120.21.1322.1322

Published: 2012

Journal Articles

TOSO Deficiency Exerts Impact On BAFF-R Expression, Thereby Causing Impaired B Cell Development in Vivo

Alexandra Schulz, PhD, Yoon Jung Park, Ph.D., Rainer Claus, MD, Hamid Kashkar, PhD, Jens Seeger, PhD, Julia Claasen, Christian P. Pallasch, MD, Christoph Plass, PhD, Michael Hallek, MD, Clemens Wendtner, Lukas P. Frenzel, MD

Blood (2012) 120 (21): 3898.

https://doi.org/10.1182/blood.V120.21.3898.3898

Published: 2012

Journal Articles

The Relative Significance of ZAP -70 Promoter Methylation As a Prognostic Factor in Previously Untreated Chronic Lymphocytic Leukemia: Validation of Results Using a Second Large CLL Research Consortium (CRC) Patient Data Set

Rainer Claus, MD, Amy S. Ruppert, MAS, David M. Lucas, PhD, Manuela Zucknick, PhD, Laura Z. Rassenti, Ph.D., Andrew Greaves, Donna S. Neuberg, ScD, William G. Wierda, MD, Ph.D., Michael J. Keating, MD, Jennifer R. Brown, MD, PhD, John G Gribben, Kanti R. Rai, M.D., Michael R. Grever, MD, Neil E. Kay, MD, Thomas J. Kipps, MD, PhD, Christoph Plass, PhD, John C. Byrd, MD

Blood (2012) 120 (21): 3865.

https://doi.org/10.1182/blood.V120.21.3865.3865

Published: 2012

NARROW

Polatuzumab Vedotin in Relapsed and Refractory (r/r) Large B-Cell Lymphoma (LBCL): Real-World Data of the German National Compassionate Use Program (CUP)

Elevated Pre-Treatment Fetal Hemoglobin Predicts Better Outcome in MDS/AML Patients Receiving 5-Aza-2'-Deoxycytidine (DAC)

Implementation of a Molecular Tumor Board in Clinical Decision Making at the Medical Center University of Freiburg

The Pan-PIM Kinase Inhibitor LGB321 Affects Apoptotic Pathways and Microenvironmental Interactions in CLL

Decitabine (DAC) in Combination with Donor Lymphocyte Infusions (DLIs) Can Induce Remissions of Overt Aml Relapses after Allogeneic Transplantation

SYK Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia

Combined Inhibition of BCR and IGF1R Signaling Leads to Synergistic Apoptosis Induction in Primary CLL Cells in Vitro

Single Cell Genotyping of Inv(16) AML in CBL Mutated Clonal Hematopoiesis Characterizes Clonal Architecture and Evolution of Exome Sequencing-Identified Mutations in the Protein Tyrosine Phosphatase Ptprt and Other Genes

Induction of an Erythroid but Not Megakaryocytic Expression Signature in Myeloid Cells By in Vitro 5-Aza-2'-Deoxycytidine Treatment

ABCB1 Expression in Acute Myeloid Leukemia (AML): A Possible Predictive Value for Treatment Resistance?

In Vivo Methylome Changes in Purified Peripheral Blood Blasts and T Cells of AML Patients Treated with Decitabine: Statistical Modelling of a Hypomethylation Response

NFATc1 Is Transcriptionally Activated in Chronic Lymphocytic Leukemia (CLL) By Promotor DNA-Hypomethylation Which Correlates with in-Vitro Vulnerability to Calcineurin Inhibitors

Differential DNA Methylation Predicts Response To Combined Treatment Regimens With a DNA Methyltransferase Inhibitor In Acute Myeloid Leukemia (AML)

Decitabine Response Associated Gene Expression Patterns In Acute Myeloid Leukemia (AML)

Heterogeneity and Evolution Of DNA Methylation In Chronic Lymphocytic Leukemia

A Complex Molecular Network Controls Palmitoylation-Dependant CD95 Sensitivity Of CLL Cells

The Hsp90 Inhibitor 17-DMAG Increases SOCS3 and Regulates Cytokine Production, Migration and Cell Death in Chronic Lymphocytic Leukemia

Aberrant Epigenetic Suppression of the Ptprot Gene Encoding a Protein Tyrosine Phosphatase Targeting KIT in Acute Myeloid Leukemia

TOSO Deficiency Exerts Impact On BAFF-R Expression, Thereby Causing Impaired B Cell Development in Vivo

The Relative Significance of ZAP -70 Promoter Methylation As a Prognostic Factor in Previously Untreated Chronic Lymphocytic Leukemia: Validation of Results Using a Second Large CLL Research Consortium (CRC) Patient Data Set

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American Society of Hematology

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ASH Publications

American Society of Hematology

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