1-12 of 12
R. Gitendra Wickremasinghe
Close
Sort by
Journal Articles

Phenethyl Isothiocyanate (PEITC) Regulates Autophagy in Chronic Lymphocytic Leukemia.

Jemimah Adams, PhD, R Gitendra Wickremasinghe, PhD, Archibald G Prentice, MBChB, FRCP, FRCPath, Jonathan C. Strefford, BSc, PhD, Andrew Duncombe, MD, Francesco Forconi, MD, Freda K. Stevenson, DPhil, Graham Packham, PhD, Andrew Steele, PhD
Journal: Blood
Blood (2012) 120 (21): 2906.
https://doi.org/10.1182/blood.V120.21.2906.2906
Published: 2012
Journal Articles

The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment

Andrew J. Steele, Archibald G. Prentice, Kate Cwynarski, A. Victor Hoffbrand, Stephen M. Hart, Mark W. Lowdell, Edward R. Samuel, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2010) 116 (22): 4569–4577.
https://doi.org/10.1182/blood-2009-09-245811
Published: 2010
Includes: Supplemental data
Journal Articles

Attenuated Measles Virus: A Promising Therapeutic Modality for B Cell Malignancy.

Bella Patel, MB BS, MD, Ehsan Ghorani, MB BS, Y. Zhang, R. Gitendra-Wickremasinghe, PhD, Andrew Steele, BSc MSc, PhD, Adele K Fielding, MB, BS, PhD
Journal: Blood
Blood (2009) 114 (22): 2460.
https://doi.org/10.1182/blood.V114.22.2460.2460
Published: 2009
Journal Articles

2-phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells

Andrew J. Steele, Archibald G. Prentice, A. Victor Hoffbrand, Birunthini C. Yogashangary, Stephen M. Hart, Mark W. Lowdell, Edward R. Samuel, Janet M. North, Elisabeth P. Nacheva, Anastasios Chanalaris, Panagiotis Kottaridis, Kate Cwynarski, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2009) 114 (6): 1217–1225.
https://doi.org/10.1182/blood-2008-11-190587
Published: 2009
Includes: Supplemental data
Journal Articles

p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism

Andrew J. Steele, Archibald G. Prentice, A. Victor Hoffbrand, Birunthini C. Yogashangary, Stephen M. Hart, Elisabeth P. Nacheva, Julie D. Howard-Reeves, Veronique M. Duke, Panagiotis D. Kottaridis, Kate Cwynarski, Lyubomir T. Vassilev, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2008) 112 (9): 3827–3834.
https://doi.org/10.1182/blood-2008-05-156380
Published: 2008
Includes: Supplemental data
Journal Articles

Pifithrin α, a Selective Inhibitor of p53-Mediated Transcription, Augments Apoptotic Killing of Chronic Lymphocytic Leukemia Cells by Nutlin 3a and Cytotoxic Drugs.

Andrew J. Steele, Archie Prentice, Kate Cwynarski, A. Victor Hoffbrand, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2007) 110 (11): 1590.
https://doi.org/10.1182/blood.V110.11.1590.1590
Published: 2007
Journal Articles

2-Phenylacetylenesulfonamide Upregulates Noxa and Induces p53-Independent Apoptosis of CLL Cells.

Andrew J. Steele, Archie Prentice, Kate Cwynarski, A. Victor Hoffbrand, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2007) 110 (11): 1609.
https://doi.org/10.1182/blood.V110.11.1609.1609
Published: 2007
Journal Articles

The Sesquiterpene Lactone Parthenolide Rapidly and Selectively Induces Apoptosis of B-Chronic Lymphocytic Leukemia Cells.

Andrew J. Steele, PhD, Anouska A. Casanova, BSc, A. Victor Hoffbrand, DSc, Atul B. Mehta, MD, Kanagasabai Ganeshaguru, PhD, Dylan T. Jones, PhD, R. Gitendra Wickremasinghe, PhD
Journal: Blood
Blood (2004) 104 (11): 3483.
https://doi.org/10.1182/blood.V104.11.3483.3483
Published: 2004
Journal Articles

Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs

Dylan T. Jones, Elena Addison, Janet M. North, Mark W. Lowdell, A. Victor Hoffbrand, Atul B. Mehta, Kanagasabai Ganeshaguru, Najeem I. Folarin, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2004) 103 (5): 1855–1861.
https://doi.org/10.1182/blood-2003-05-1603
Published: 2004
Journal Articles

Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis

Dylan T. Jones, Kanagasabai Ganeshaguru, Robert J. Anderson, Trevor R. Jackson, K. Richard Bruckdorfer, Sylvia Y. Low, Lars Palmqvist, H. Grant Prentice, A. Victor Hoffbrand, Atul B. Mehta, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2003) 101 (8): 3174–3180.
https://doi.org/10.1182/blood-2002-07-2143
Published: 2003
Journal Articles

Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediate killing of B-chronic lymphocytic leukemia cells by cytotoxic drugs or γ radiation

Dylan T. Jones, Kanagasabai Ganeshaguru, Andres E. Virchis, Najeem I. Folarin, Mark W. Lowdell, Atul B. Mehta, H. Grant Prentice, A. Victor Hoffbrand, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2001) 98 (9): 2800–2807.
https://doi.org/10.1182/blood.V98.9.2800
Published: 2001
Journal Articles

Biochemical and Genetic Control of Apoptosis: Relevance to Normal Hematopoiesis and Hematological Malignancies

R. Gitendra Wickremasinghe, A. Victor Hoffbrand
Journal: Blood
Blood (1999) 93 (11): 3587–3600.
https://doi.org/10.1182/blood.V93.11.3587
Published: 1999