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Archibald G. Prentice
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Journal Articles

Phenethyl Isothiocyanate (PEITC) Regulates Autophagy in Chronic Lymphocytic Leukemia.

Jemimah Adams, PhD, R Gitendra Wickremasinghe, PhD, Archibald G Prentice, MBChB, FRCP, FRCPath, Jonathan C. Strefford, BSc, PhD, Andrew Duncombe, MD, Francesco Forconi, MD, Freda K. Stevenson, DPhil, Graham Packham, PhD, Andrew Steele, PhD
Journal: Blood
Blood (2012) 120 (21): 2906.
https://doi.org/10.1182/blood.V120.21.2906.2906
Published: 2012
Journal Articles

The p90RSK Inhibitor BI-D1870 Induces Apoptosis in CLL Cells

Andrew J Steele, PhD, Archibald G Prentice, MBChB, FRCP, FRCPath, Victoria Last, PhD, A. Victor Hoffbrand, DM, DSc, R G Wickremasinghe
Journal: Blood
Blood (2011) 118 (21): 2492.
https://doi.org/10.1182/blood.V118.21.2492.2492
Published: 2011
Journal Articles

The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment

Andrew J. Steele, Archibald G. Prentice, Kate Cwynarski, A. Victor Hoffbrand, Stephen M. Hart, Mark W. Lowdell, Edward R. Samuel, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2010) 116 (22): 4569–4577.
https://doi.org/10.1182/blood-2009-09-245811
Published: 2010
Includes: Supplemental data
Journal Articles

The impact on outcome of the addition of all- trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1 , FLT3 , and CEBPA

Clinical Trials & Observations
Alan K. Burnett, Robert K. Hills, Claire Green, Sarah Jenkinson, Kenneth Koo, Yashma Patel, Carol Guy, Amanda Gilkes, Donald W. Milligan, Anthony H. Goldstone, Archibald G. Prentice, Keith Wheatley, David C. Linch, Rosemary E. Gale
Journal: Blood
Blood (2010) 115 (5): 948–956.
https://doi.org/10.1182/blood-2009-08-236588
Published: 2010
Includes: Supplemental data
Journal Articles

Induction of Noxa Via Generation of Reactive Oxygen Species Plays a Key Role in Induction of CLL Cell Apoptosis by Two Novel p53-Independent Cytotoxic Agents.

Andrew Steele, BSc, MSc, PhD, Archibald G Prentice, MBChB, FRCP, FRCPath, Anastasios Chanalaris, A. Victor Hoffbrand, DM, FRCP, FRCPath, DSc, Kate Cwynarski, Ranmohan Wickremasinghe
Journal: Blood
Blood (2009) 114 (22): 2752.
https://doi.org/10.1182/blood.V114.22.2752.2752
Published: 2009
Journal Articles

2-phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells

Andrew J. Steele, Archibald G. Prentice, A. Victor Hoffbrand, Birunthini C. Yogashangary, Stephen M. Hart, Mark W. Lowdell, Edward R. Samuel, Janet M. North, Elisabeth P. Nacheva, Anastasios Chanalaris, Panagiotis Kottaridis, Kate Cwynarski, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2009) 114 (6): 1217–1225.
https://doi.org/10.1182/blood-2008-11-190587
Published: 2009
Includes: Supplemental data
Journal Articles

Clinically Significant Responses Achieved with Romidepsin in Treatment-Refractory Cutaneous T-Cell Lymphoma: Final Results from a Phase 2B, International, Multicenter, Registration Study

Youn Kim, MD, Sean Whittaker, MD, FRCP, Marie France Demierre, MD, Alain H Rook, MD, Adam Lerner, MD, Madeleine Duvic, MD, Sunil Reddy, MD, Ellen J Kim, MD, Tadeusz Robak, MD, Jürgen C Becker, MD, Alexey Samtsov, MD, William McCulloch, MB, FRCP, Archibald G Prentice, MBChB, FRCP, FRCPath
Journal: Blood
Blood (2008) 112 (11): 263.
https://doi.org/10.1182/blood.V112.11.263.263
Published: 2008
Journal Articles

p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism

Andrew J. Steele, Archibald G. Prentice, A. Victor Hoffbrand, Birunthini C. Yogashangary, Stephen M. Hart, Elisabeth P. Nacheva, Julie D. Howard-Reeves, Veronique M. Duke, Panagiotis D. Kottaridis, Kate Cwynarski, Lyubomir T. Vassilev, R. Gitendra Wickremasinghe
Journal: Blood
Blood (2008) 112 (9): 3827–3834.
https://doi.org/10.1182/blood-2008-05-156380
Published: 2008
Includes: Supplemental data
Journal Articles

Romidepsin (depsipeptide) Induces Clinically Significant Responses in Treatment-Refractory CTCL: An International, Multicenter Study.

Youn H. Kim, MD, Sunil Reddy, MD, Ellen J. Kim, MD, Alain H. Rook, MD, Adam Lerner, MD, Mariefrance Demierre, MD, Madeleine Duvic, MD, Sean Whittaker, MD, FRCP, Tadeusz Robak, MD, Jurgen C. Becker, MD, William McCulloch, MB, FRCP, Archibald G. Prentice, MB, FRCP, FRCPath, on behalf of All Investigators
Journal: Blood
Blood (2007) 110 (11): 123.
https://doi.org/10.1182/blood.V110.11.123.123
Published: 2007
Journal Articles

ZAP-70 expression is associated with enhanced ability to respond to migratory and survival signals in B-cell chronic lymphocytic leukemia (B-CLL)

Sarah J. Richardson, Christine Matthews, Mark A. Catherwood, H. Denis Alexander, B. Sean Carey, Joanna Farrugia, Anne Gardiner, Sarah Mould, David Oscier, J. Adrian Copplestone, Archibald G. Prentice
Journal: Blood
Blood (2006) 107 (9): 3584–3592.
https://doi.org/10.1182/blood-2005-04-1718
Published: 2006