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Journal Articles

Aberrant rRNA 2'-O-Methylation Causes Bone Marrow Failure and Defective Immune Function

Daphna Nachmani, Lourdes M. Mendez, MD PhD, Pier Paolo Pandolfi, MD PhD

Blood (2020) 136 (Supplement 1): 11–12.

https://doi.org/10.1182/blood-2020-141809

Published: 2020

Journal Articles

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression

Miguel Gallardo, PhD, Hun Ju Lee, MD, Xiaorui Zhang, Laura R. Pageon, Asha Multani, Markus Reschke, PhD, John G Clohessy, Alfonso Quintás-Cardama, MD, Michael Andreeff, MD PhD, Steven M. Kornblau, MD, Pier Paolo Pandolfi, MD PhD, Sean M. Post, PhD

Blood (2014) 124 (21): 2382.

https://doi.org/10.1182/blood.V124.21.2382.2382

Published: 2014

Journal Articles

The BRAF Pseudogene Is a Proto-Oncogenic Competitive Endogenous RNA

Florian Karreth, PhD, Markus Reschke, PhD, Bjoern Chapuy, MD PhD, Margaret A. Shipp, MD, Roberto Chiarle, MD, Pier Paolo Pandolfi, MD PhD

Blood (2014) 124 (21): 263.

https://doi.org/10.1182/blood.V124.21.263.263

Published: 2014

Journal Articles

In Vivo Analysis of PML-RARA in a Humanized Mouse Model

Hiromichi Matsushita, MD PhD, Takashi Yahata, PhD, Yin Sheng, PhD, Yoshihiko Nakamura, PhD, Yukari Muguruma, PhD, Hideyuki Matsuzawa, Masayuki Tanaka, Hideki Hayashi, Tadayuki Sato, Anar Damdinsuren, MD, Makoto Onizuka, MD PhD, Mamoru Ito, Hayato Miyachi, MD PhD, Pier Paolo Pandolfi, MD PhD, Kiyoshi Ando

Blood (2014) 124 (21): 1020.

https://doi.org/10.1182/blood.V124.21.1020.1020

Published: 2014

Journal Articles

MUC1 Expression Is Essential For Establishment Of Acute Myeloid Leukemia In Vivo

Dina Stroopinsky, PhD, Hasan Rajabi, PhD, Jacalyn Rosenblatt, MD, Heidi Mills, BA, Turner Kufe, Katarina Luptakova, MD, Baldev Vasir, PhD, Maxwell D Coll, Palmer Kristen, Akriti Kharbanda, Srivastava Neeharika, MD, Robin Joyce, MD, James D. Levine, MD, Jon Arnason, MD, Richard M. Stone, MD, Pier Paolo Pandolfi, MD, PhD, Donald Kufe, MD, David Avigan, MD

Blood (2013) 122 (21): 3787.

https://doi.org/10.1182/blood.V122.21.3787.3787

Published: 2013

Journal Articles

ceRNAs and ceRNA Networks in Normal and Malignant Hematopoiesis and Their Therapeutic Implications

Pier Paolo Pandolfi, MD, PhD

Blood (2013) 122 (21): SCI-30.

https://doi.org/10.1182/blood.V122.21.SCI-30.SCI-30

Published: 2013

Journal Articles

A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division.

Keisuke Ito, M.D., Ph.D., Arkaitz Carracedo, Ph.D., Fumio Arai, DDS, PhD, Ugo Ala, Ph.D., David Avigan, MD, Zachary Schafer, Ph.D., Ron M. Evans, PhD, Toshio Suda, MD, Chih-Hao Lee, Pier Paolo Pandolfi, MD, PhD

Blood (2012) 120 (21): 2327.

https://doi.org/10.1182/blood.V120.21.2327.2327

Published: 2012

Journal Articles

Targeting Leukemia Initiating Cells by MUC1-C Subunit Inhibition

Blood (2012) 120 (21): 3583.

https://doi.org/10.1182/blood.V120.21.3583.3583

Published: 2012

Journal Articles

Upregulation of eIF4E in Nucleophosmin 1 (NPM1) Haploinsufficient Cells Alters CCAAT Enhancer Binding Protein Alpha (C/EBPα) Activity: Implications for MDS and AML

Nirmalee Abayasekara, MS, Michelle Levine, BS, Niccolo Bolli, MD, Hong Sun, MD, Matthew Silver, BS, Navid Nia, Paolo Sportoletti, MD, Pier Paolo Pandolfi, MD, PhD, Nancy Berliner, MD, Arati Khanna-Gupta, PhD

Blood (2011) 118 (21): 2432.

https://doi.org/10.1182/blood.V118.21.2432.2432

Published: 2011

Journal Articles

A Dual Proto-Oncogenic and Tumor Suppressive Role of LRF/POKEMON In Hemopoietic Malignancies through Control of Cell Fate Decision

Pier Paolo Pandolfi, MD, PhD

Blood (2010) 116 (21): SCI-14.

https://doi.org/10.1182/blood.V116.21.SCI-14.SCI-14

Published: 2010

Journal Articles

Targeting Acute Myeloid Leukemia Stem Cells by MUC1-C Subunit Inhibition

Dina Stroopinsky, PhD, Jacalyn Rosenblatt, MD, MSc, Keisuke Ito, MD, PhD, Li Yin, Hasan Rajabi, PhD, Baldev Vasir, PhD, Turner Kufe, Brett Glotzbecker, MD, Katarina Luptakova, MD, Heidi Mills, BA, Robin Joyce, MD, Dimitrios Tzachanis, MD, PhD, Vassiliki A Boussiotis, MD, PhD, James Levine, MD, Ilene Galinsky, ANP, Richard Stone, MD, Pier Paolo Pandolfi, MD, PhD, Donald Kufe, MD, David Avigan, MD

Blood (2010) 116 (21): 848.

https://doi.org/10.1182/blood.V116.21.848.848

Published: 2010

Journal Articles

The Role of Nucleophosmin In Hematopoietic Stem Cells and the Pathogenesis of Myelodysplastic Syndrome

Keisuke Ito, MD, PhD, Paolo Sportoletti, MD, John G Clohessy, PhD, Grisendi Silvia, PhD, Pier Paolo Pandolfi, MD, PhD

Blood (2010) 116 (21): 95.

https://doi.org/10.1182/blood.V116.21.95.95

Published: 2010

Journal Articles

BCL11B Mutations In T-Cell Acute Lymphoblastic Leukemia

Blood (2010) 116 (21): 471.

https://doi.org/10.1182/blood.V116.21.471.471

Published: 2010

Journal Articles

Cytoplasmic Nucleophosmin (NPMc+) Mutations and FMS-Like Tyrosine Kinase 3 (Flt3) Internal Tandem Duplication (ITD) Mutations Cooperate to Cause Leukemia In a Mouse Model

Rachel E. Rau, MD, Daniel Magoon, Emily McIntyre, Li Li, PhD, Sarah Greenblatt, David Huso, DVM, PhD, Pier Paolo Pandolfi, MD, PhD, Donald Small, MD, PhD, Patrick Brown, MD

Blood (2010) 116 (21): 145.

https://doi.org/10.1182/blood.V116.21.145.145

Published: 2010

Journal Articles

Nucleophosmin Is Required for Macrophage Function and Maturation.

Paolo Sportoletti, MD, John G Clohessy, Luisa Riccardi, MD, Arati Khanna-Gupta, PhD, Jian Chen, Nancy Berliner, MD, Pier Paolo Pandolfi, MD, PhD

Blood (2009) 114 (22): 238.

https://doi.org/10.1182/blood.V114.22.238.238

Published: 2009

Journal Articles

Akt-Mediated Phosphorylation of Bmi1 Regulates Its Chromatin Association and Growth Promoting Properties.

Yan Liu, Fan Liu, Ph.D., Xinyang Zhao, Goro Sashida, Anthony Deblasio, Zhenbang Chen, Hui-kuan Lin, Silvana Di Giandomenico, Shannon Elf, Youyang Yang, Yasuhiko Miyata, MD, PhD, Gang Huang, Ph.D., Silvia Menendez, Ingo Mellinghoff, MD, Pier Paolo Pandolfi, MD, PhD, Cyrus V. Hedvat, MD, PhD, Stephen D. Nimer

Blood (2009) 114 (22): 3605.

https://doi.org/10.1182/blood.V114.22.3605.3605

Published: 2009

Journal Articles

Nucleophosmin-1 Interacts with CCAAT Enhancer Binding Protein Alpha (C/EBPα) to Facilitate Granulocyte Maturation: Implications in MDS and AML.

Arati Khanna-Gupta, PhD, Jian Chen, Matthew Silver, BS, Hong Sun, Nirmalee Abayasekara, MS, Stephanie Halene, MD, Paolo Sportoletti, MD, Pier Paolo Pandolfi, MD, PhD, Nancy Berliner, MD

Blood (2009) 114 (22): 2768.

https://doi.org/10.1182/blood.V114.22.2768.2768

Published: 2009

Journal Articles

Generation of a Factor Dependent Myeloid Cell Line from Nucleophosmin-1 Heterozygous (NPM-1+/−) Mouse Bone Marrow as a Model for 5q- MDS

Arati Khanna-Gupta, PhD, Hong Sun, Jian Chen, Stephanie Halene, MD, Paolo Sportoletti, MD, Pier Paolo Pandolfi, MD, PhD, Nancy Berliner

Blood (2008) 112 (11): 852.

https://doi.org/10.1182/blood.V112.11.852.852

Published: 2008

Journal Articles

The Pokemon/LRF-Notch Paradigm.

Pier Paolo Pandolfi, MD, PhD

Blood (2008) 112 (11): sci-29.

https://doi.org/10.1182/blood.V112.11.sci-29.sci-29

Published: 2008

Journal Articles

PML Controls PTEN Localization and Function in APL through a Novel Deubiquitination Pathway

Arkaitz Carracedo, MIn-Sup Song, Leonardo Salmena, Ainara Egia, Francesco Lo-Coco, Julie Teruya-Feldstein, MD, Pier Paolo Pandolfi, MD, PhD

Blood (2008) 112 (11): 3812.

https://doi.org/10.1182/blood.V112.11.3812.3812

Published: 2008

NARROW

Aberrant rRNA 2'-O-Methylation Causes Bone Marrow Failure and Defective Immune Function

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression

The BRAF Pseudogene Is a Proto-Oncogenic Competitive Endogenous RNA

In Vivo Analysis of PML-RARA in a Humanized Mouse Model

MUC1 Expression Is Essential For Establishment Of Acute Myeloid Leukemia In Vivo

ceRNAs and ceRNA Networks in Normal and Malignant Hematopoiesis and Their Therapeutic Implications

A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division.

Targeting Leukemia Initiating Cells by MUC1-C Subunit Inhibition

Upregulation of eIF4E in Nucleophosmin 1 (NPM1) Haploinsufficient Cells Alters CCAAT Enhancer Binding Protein Alpha (C/EBPα) Activity: Implications for MDS and AML

A Dual Proto-Oncogenic and Tumor Suppressive Role of LRF/POKEMON In Hemopoietic Malignancies through Control of Cell Fate Decision

Targeting Acute Myeloid Leukemia Stem Cells by MUC1-C Subunit Inhibition

The Role of Nucleophosmin In Hematopoietic Stem Cells and the Pathogenesis of Myelodysplastic Syndrome

BCL11B Mutations In T-Cell Acute Lymphoblastic Leukemia

Cytoplasmic Nucleophosmin (NPMc+) Mutations and FMS-Like Tyrosine Kinase 3 (Flt3) Internal Tandem Duplication (ITD) Mutations Cooperate to Cause Leukemia In a Mouse Model

Nucleophosmin Is Required for Macrophage Function and Maturation.

Akt-Mediated Phosphorylation of Bmi1 Regulates Its Chromatin Association and Growth Promoting Properties.

Nucleophosmin-1 Interacts with CCAAT Enhancer Binding Protein Alpha (C/EBPα) to Facilitate Granulocyte Maturation: Implications in MDS and AML.

Generation of a Factor Dependent Myeloid Cell Line from Nucleophosmin-1 Heterozygous (NPM-1+/−) Mouse Bone Marrow as a Model for 5q- MDS

The Pokemon/LRF-Notch Paradigm.

PML Controls PTEN Localization and Function in APL through a Novel Deubiquitination Pathway

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American Society of Hematology

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ASH Publications

American Society of Hematology

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