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Journal Articles

JAK2 V617F Impairs T Cell Differentiation in Polycythemia Vera

Daniel C Choi, Ghaith Abu-Zeinah, Silvana Di Giandomenico, Katie Erdos, Joseph Scandura
Journal: Blood
Blood (2022) 140 (Supplement 1): 6746–6747.
https://doi.org/10.1182/blood-2022-167785
Published: 2022
Journal Articles

Diffuse Large B Cell Pdtx in Humanized Mice Are Valuable Models to Study Host-Lymphoma Interactions and Immune-Modulating Agents

Giorgia Zanetti, Giuseppina Astone, Luca Cappelli, William Chiu, Maria Teresa Cacciapuoti, Clarisse Kayembe, Danilo Fiore, Wayne Tam, Joseph Scandura, Silvana Di Giandomenico, Lorenzo Galluzzi, Lisa Giulino Roth, Giorgio Inghirami
Journal: Blood
Blood (2021) 138 (Supplement 1): 2406.
https://doi.org/10.1182/blood-2021-151598
Published: 2021
Journal Articles

Hematopoietic Stem and Progenitor Cell Fitness As a Novel Prognostic and Monitoring Biomarker for JAK2 V617F Myeloproliferative Neoplasms (MPNs)

Ghaith Abu-Zeinah, Silvana Di Giandomenico, Tatiana Cruz, Daniel Choi, Elwood Taylor, III, Ellen Ritchie, Richard T. Silver, Joseph Scandura
Journal: Blood
Blood (2021) 138 (Supplement 1): 627.
https://doi.org/10.1182/blood-2021-153003
Published: 2021
Journal Articles

Megakaryocyte TGFβ1 partitions erythropoiesis into immature progenitor/stem cells and maturing precursors

Silvana Di Giandomenico, Pouneh Kermani, Nicole Mollé, Maria Mia Yabut, Ghaith Abu-Zeinah, Thomas Stephens, Nassima Messali, Ryan Schreiner, Fabienne Brenet, Shahin Rafii, Joseph M. Scandura
Journal: Blood
Blood (2020) 136 (9): 1044–1054.
https://doi.org/10.1182/blood.2019003276
Published: 2020
Includes: Supplemental data
Journal Articles

Low-Dose Epo after Tgfβ Blockade Triggers Robust Erythropoiesis and Increased RBC Production

Silvana Di Giandomenico, PhD, Ghaith Abu Zeinah, MD, Pouneh Kermani, PhD, Mia Yabut, BS, Thomas Stephens, BS, Nassima Messali, PhD, Joseph Scandura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2217.
https://doi.org/10.1182/blood-2019-129044
Published: 2019
Journal Articles

Myeloproliferative Neoplasm (MPN) Driver Mutations Are Enriched during Hematopoietic Stem Cell Differentiation in Patterns That Correlate with Clinical Phenotype and Treatment Response

Ghaith Abu-Zeinah, MD, Silvana Di Giandomenico, PhD, Claudia Sosner, BA, Niamh Savage, BA, Spencer Krichevsky, BS, Ellen K. Ritchie, MD, Pouneh Kermani, PhD, Richard T. Silver, MD, Joseph Scandura, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4317.
https://doi.org/10.1182/blood-2018-99-117744
Published: 2018
Journal Articles

Megakaryocytic TGFβ1 Partitions Hematopoiesis into Amplifying Stem and Progenitor Cells and Maturing Effector Cells

Silvana Di Giandomenico, PhD, Pouneh Kermani, PhD, Nicole Molle, BS, Mia Yabut, BS, Fabienne Brenet, PhD, Shahin Rafii, MD, Joseph Scandura, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 81.
https://doi.org/10.1182/blood.V130.Suppl_1.81.81
Published: 2017
Journal Articles

Controlling Hematopoietic Stem Cell Quiescence By Ablating the TGFβ-Responsive, Hematopoietic-Hpecific Enhancer of CDKN1C (p57)

Mia Yabut, BS, Fabienne Brenet, PhD, Nassima Messali, PhD, Nicole Molle, BS, Pouneh Kermani, PhD, Silvana Di Giandomenico, PhD, Matthew Brown, BS, Joseph Scandura, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2436.
https://doi.org/10.1182/blood.V130.Suppl_1.2436.2436
Published: 2017
Journal Articles

Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells

Takashi Asai, Yan Liu, Silvana Di Giandomenico, Narae Bae, Delphine Ndiaye-Lobry, Anthony Deblasio, Silvia Menendez, Yevgeniy Antipin, Boris Reva, Rachel Wevrick, Stephen D. Nimer
Journal: Blood
Blood (2012) 120 (8): 1601–1612.
https://doi.org/10.1182/blood-2011-11-393983
Published: 2012
Includes: Supplemental data
Journal Articles

Akt-Mediated Phosphorylation of Bmi1 Regulates Its Chromatin Association and Growth Promoting Properties.

Yan Liu, Fan Liu, Ph.D., Xinyang Zhao, Goro Sashida, Anthony Deblasio, Zhenbang Chen, Hui-kuan Lin, Silvana Di Giandomenico, Shannon Elf, Youyang Yang, Yasuhiko Miyata, MD, PhD, Gang Huang, Ph.D., Silvia Menendez, Ingo Mellinghoff, MD, Pier Paolo Pandolfi, MD, PhD, Cyrus V. Hedvat, MD, PhD, Stephen D. Nimer
Journal: Blood
Blood (2009) 114 (22): 3605.
https://doi.org/10.1182/blood.V114.22.3605.3605
Published: 2009
Journal Articles

Necdin Regulates Hematopoietic Stem Cell Quiescence and Sensitivity to Genotoxic Stress.

Takashi Asai, Yan Liu, Silvana Di Giandomenico, Anthony Deblasio, Silvia Menendez, Jack Antipin, Boris Reva, Rachel Wevrick, Stephen D. Nimer
Journal: Blood
Blood (2009) 114 (22): 379.
https://doi.org/10.1182/blood.V114.22.379.379
Published: 2009