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Pauline Robbe, MSc
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Journal Articles

Multicentre Genome Wide Association Study Identifies Risk Alleles for Progressive Chronic Lymphocytic Leukaemia

David Allsup, BSc, MBBS, FRCP, FRCPath, PhD, Wei Yu Lin, PhD, Sarah Elizabeth Fordham, PhD BSc, Nicola Sunter, Claire Elstob, PhD, Thahira Rahman, PhD, Elaine Willmore, Colin Shepherd, Gordon Strathdee, BSc, PhD, Timothy Barrow, PhD, Tryfonia Mainou-Fowler, Rachel Piddock, Helen Marr, PhD, Jonathan Wallis, Scott R. Marshall, BSc,MDPhD, Geoffery Summerfield, Andrew Pettitt, FRCPath, PhD, Chris Pepper, BSc, PhD, Christopher Fegan, MB, MD FRCP, FRCPath, Francesco Forconi, MD DM, PhD FRCPath, Martin J.S. Dyer, Sandrine Jayne, PhD, April Sellors, Anna Schuh, PhD, Pauline Robbe, MSc, PhD, David Oscier, Richard S. Houlston, James Bailey, PhDFRCPath,MRCP,MD, Syed Ashar Rais, Alison Bentley, Lynn Cawkwell, Peter Hillmen, MD PhD, Guy Pratt, James M. Allan
Journal: Blood
Blood (2019) 134 (Supplement_1): 1740.
https://doi.org/10.1182/blood-2019-122037
Published: 2019
Journal Articles

Highly Comprehensive Genomic Testing for CLL: WGS, One Key to CLL Patient Stratification

Kate E Ridout, PhD, Pauline Robbe, MSc, PhD, Doriane Cavalieri, MSc, Jennifer Becq, PhD, Miao He, PhD, Ruth Clifford, FRCPath, PhD, Niamh Appleby, FRCPath, MD, Reem Alsolami, PhD, Adam Burns, BSc, PhD, Melanie Oates, PhD, Basile Stamatopoulos, PhD, Samantha Knight, PhD, Alona Sosinsky, PhD, Pavlos Antoniou, PhD, Mark Ross, PhD, David Bentley, PhD, Andrew Pettitt, FRCPath, PhD, Peter Hillmen, MB ChB, PhD FRCP, FRCPath, Mark Caulfield, PhD, Anna Schuh, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3115.
https://doi.org/10.1182/blood-2018-99-115935
Published: 2018
Journal Articles

p53 Functional Assessment and Correlation with 17p Deletion and/or TP53 Mutation Status: Final Report of the ICLL001 Bomp Trial

Magali Le Garff-Tavernier, Claire Quiney, Lauren Veronese, MD PhD, Florence Nguyen-Khac, MD PhD, Pauline Robbe, MSc, PhD, Patricia Combes, Marie-Sarah Dilhuydy, MD, Pierre Feugier, Beatrice Mahe, MD, Laurence Sanhes, MD, Alain Jacques Delmer, MD, Loic Ysebaert, MD PhD, Malgorzata Truchan-Graczyk, Brigitte Dreyfus, MD, Choquet Sylvain, MD, Thérèse Aurran, MD, Emmanuelle Ferrant, MD, Caroline Dartigeas, MD, Stéphane Leprêtre, MD, Gian Matteo Pica, MD, Frederic Davi, MD PhD, Bruno Pereira, Roselyne Delepine, Anna Schuh, MD PhD, Romain Guieze, MD, Jacques-Olivier Bay, MD PhD, Véronique Leblond, MD PhD, Helene Merle-Beral, MD PhD, Sophie de Guibert, MD, Olivier Tournilhac, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3127.
https://doi.org/10.1182/blood-2018-99-116722
Published: 2018
Journal Articles

Detection of Clinically Relevant Molecular Alterations in Chronic Lymphocytic Leukemia (CLL) By Nanopore Sequencing

Adam Burns, BSc, PhD, David Robert Bruce, MRCP, Pauline Robbe, MSc, PhD, Adele Timbs, Basile Stamatopoulos, PhD, Ruth Clifford, FRCPath, PhD, Maria Lopopolo, Duncan Parkes, Kate E Ridout, PhD, Anna Schuh, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1847.
https://doi.org/10.1182/blood-2018-99-110948
Published: 2018
Journal Articles

The Contribution of Gene Mutations to Long-Term Clinical Outcomes: Data from the Randomised UK LRF CLL4 Trial

Stuart Blakemore, PhD, Ruth Clifford, Pavlos Antoniou, Helen Parker, PhD, Pauline Robbe, MSc, Marta Larrayoz, PhD, Zadie Davis, Latha Kadalyayil, Andrew Collins, Jade Forster, PhD, Monica Else, Andrew J Steele, PhD, Jacqueline Chan, PhD, Graham Speight, PhD, Mark Cragg, PhD, Matthew John Jerome Rose-Zerilli, PhD, Daniel Catovsky, MD FRCP, David Oscier, MD PhD, Anna Schuh, MD PhD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 259.
https://doi.org/10.1182/blood.V130.Suppl_1.259.259
Published: 2017
Journal Articles

Clinical Importance of DNA Methylation Signatures in Chronic Lymphocytic Leukaemia Patients Treated with Chemo-Immunotherapy

Harindra Amarasinghe, PhD, Tomasz K Wojdacz, PhD MSc, Matthew John Jerome Rose-Zerilli, PhD, Alice Beattie, Jade Forster, PhD, Latha Kadalayil, Stuart Blakemore, PhD, Helen Parker, PhD, Marta Larrayoz, PhD, Ruth Clifford, Zadie Davis, Monica Else, Dena Cohen, Andrew J Steele, PhD, Richard Rosenquist, MD PhD, Andrew Collins, Andrew Pettitt, FRCPath, PhD, Peter Hillmen, MBChB, PhD, Pauline Robbe, MSc, Christopher Plass, Anna Schuh, MD PhD, Daniel Catovsky, MD FRCP, David Oscier, MD PhD, Christopher C. Oakes, PhD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 56.
https://doi.org/10.1182/blood.V130.Suppl_1.56.56
Published: 2017
Journal Articles

Next-Generation Deep Sequencing Reveals Multiple Ighv Clones in One Third of CLL Patients Defining New Prognostic Subgroups and Improving Previous Classification

Basile Stamatopoulos, PhD, Adele Timbs, Msc, Hélène Dreau, MSc, Ruth Clifford, Pauline Robbe, MSc, Adam Burns, BSc, Joanne Mason, PhD, Anna Schuh, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4127.
https://doi.org/10.1182/blood.V126.23.4127.4127
Published: 2015
Journal Articles

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Matthew John Jerome Rose-Zerilli, PhD, Helen Parker, Marta Larrayoz, PhD, Ruth Clifford, Stuart Blakemore, Jennifer Edelmann, MD, Jane Gibson, Jun Wang, Viktor Ljungstrom, Tracy Chaplin, Ali Roghanian, Zadie Davis, Anton Parker, BSc, Eugen Tausch, MD, Stavroula Ntoufa, Sara Ramos, Pauline Robbe, MSc, Andrew J Steele, PhD, Graham Packham, PhD, Ana E. Rodriguez, Lee Brown, Feargal McNicholl, Francesco Forconi, MD DM, PhD FRCPath, Andrew R Pettitt, MRCP PhD, Peter Hillmen, Martin J.S. Dyer, Prof., Mark S Cragg, PhD, Bryan D Young, BSc, PhD, Claude Chelala, Richard Rosenquist, Kostas Stamatopoulos, MD, Stephan Stilgenbauer, Samantha Knight, Anna Schuh, MD PhD, David Oscier, Jonathan C Strefford, PhD
Journal: Blood
Blood (2015) 126 (23): 365.
https://doi.org/10.1182/blood.V126.23.365.365
Published: 2015
Journal Articles

Mutational Landscape of 118 Relapsed Chronic Lymphocytic Leukemia Clinical Trial Samples; Evidence for a Multiple-Hit Profile Using Targeted Next Generation Sequencing

Pauline Robbe, MSc, Romain Guièze, MD, Ruth M Clifford, MD, Sophie de Guibert, Adele Timbs, MSc, Marie-Sarah Dilhuydy, MD, Maite Cabes, BSc, Loic Ysebaert, MDPhD, Adam Burns, BSc, Florence Nguyen-Khac, MDPhD, Frederic Davi, MD PhD, Lauren Veronese, MD PhD, Patricia Combes, Magali Le Garff-Tavernier, MD PhD, Veronique Leblond, MD PhD, Hélène Merle-Béral, MD PhD, Reem Alsolami, MSc, Susanne Weller, PhD, Angela Hamblin, MDPhD, Joanne Mason, PhD, Andrew R Pettitt, MRCP, PhD, Peter Hillmen, MB, ChB, PhD, Jenny Taylor, DPhil, Samantha JL Knight, PhD CBiol, MSB, FRCPath, Anna Schuh, MDPhD, Olivier Tournilhac, MD
Journal: Blood
Blood (2014) 124 (21): 1974.
https://doi.org/10.1182/blood.V124.21.1974.1974
Published: 2014
Journal Articles

Whole Genome Sequencing, Targeted Deep Sequencing and Copy-Number Analysis Provide a Comprehensive Picture of the Mutational Landscape of 41 Clinically Annotated CLL Cases

Adam Burns, BSc, Susanne Weller, PhD, Sean Humphray, PhD, Jennifer Becq, PhD, Reem Alsolami, MSc, Angela Hamblin, MDPhD, Ruth M Clifford, MD, Samantha JL Knight, PhD CBiol, MSB, FRCPath, Pauline Robbe, MSc, Maite Cabes, BSc, Joanne Mason, PhD, Chris S.R Hatton, MD, Jenny Taylor, DPhil, David Bentley, DPhil, Anna Schuh, MDPhD
Journal: Blood
Blood (2014) 124 (21): 1958.
https://doi.org/10.1182/blood.V124.21.1958.1958
Published: 2014
Journal Articles

The Identification of Further Minimal Regions of Overlap in Chronic Lymphocytic Leukemia Using High-Resolution SNP Arrays

Samantha JL Knight, PhD CBiol, MSB, FRCPath, Ruth Clifford, MD, Pauline Robbe, MSc, Sara DC Ramos, MSc, Adam Burns, BSc, Adele T Timbs, MSc, Reem Alsolami, BSc, Susanne Weller, PhD, Angela Hamblin, MDPhD, Joanne Mason, PhD, Melanie Oates, PhD, Michalis Titsias, PhD, Christopher Yau, DPhil, Chris C Holmes, PhD, Andrew R Pettitt, FRCP, PhD, Peter Hillmen, MB, ChB, PhD, Jenny Taylor, DPhil, Anna Shuh, MD PhD FRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 3315.
https://doi.org/10.1182/blood.V124.21.3315.3315
Published: 2014
Journal Articles

Development and Evaluation of the Clinical Utility of a Next Generation Sequencing (NGS) Tool for Myeloid Disorders

Angela Hamblin, MDPhD, Adam Burns, BSc, Christopher Tham, BA, Ruth Clifford, MD, Pauline Robbe, MSc, Adele Timbs, MSc, Joanne Mason, PhD, Helene Dreau, MSc, Andreas Weller, PhD, Puthen Jithesh, PhD, Olivia Fox, BSc, Melody Tabiner, MA, Adam Mead, MDPhD, Andrew Peniket, MD, Paresh Vyas, MDPhD, Shirley Henderson, PhD, Anna Schuh, MDPhD
Journal: Blood
Blood (2014) 124 (21): 2373.
https://doi.org/10.1182/blood.V124.21.2373.2373
Published: 2014
Journal Articles

Towards Response Prediction Using Integrated Genomics in Chronic Lymphocytic Leukaemia: Results on 250 First-Line FCR Treated Patients from UK Clinical Trials

Ruth M Clifford, MD, Pauline Robbe, MSc, Susanne Weller, PhD, Adele T Timbs, MSc, Michalis Titsias, PhD, Adam Burns, BSc, Maite Cabes, BSc, Reem Alsolami, MSc, Christopher Yau, DPhil, Angela Hamblin, MDPhD, Joanne Mason, PhD, Melanie Oates, PhD, Andrew Pettitt, MD PhD, Chris Holmes, PhD, Peter Hillmen, MB, ChB, PhD, Jenny Taylor, DPhil, Samantha JL Knight, PhD CBiol, MSB, FRCPath, Anna Schuh, MDPhD
Journal: Blood
Blood (2014) 124 (21): 1942.
https://doi.org/10.1182/blood.V124.21.1942.1942
Published: 2014