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Elaine Willmore
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Journal Articles

Multicentre Genome Wide Association Study Identifies Risk Alleles for Progressive Chronic Lymphocytic Leukaemia

David Allsup, BSc, MBBS, FRCP, FRCPath, PhD, Wei Yu Lin, PhD, Sarah Elizabeth Fordham, PhD BSc, Nicola Sunter, Claire Elstob, PhD, Thahira Rahman, PhD, Elaine Willmore, Colin Shepherd, Gordon Strathdee, BSc, PhD, Timothy Barrow, PhD, Tryfonia Mainou-Fowler, Rachel Piddock, Helen Marr, PhD, Jonathan Wallis, Scott R. Marshall, BSc,MDPhD, Geoffery Summerfield, Andrew Pettitt, FRCPath, PhD, Chris Pepper, BSc, PhD, Christopher Fegan, MB, MD FRCP, FRCPath, Francesco Forconi, MD DM, PhD FRCPath, Martin J.S. Dyer, Sandrine Jayne, PhD, April Sellors, Anna Schuh, PhD, Pauline Robbe, MSc, PhD, David Oscier, Richard S. Houlston, James Bailey, PhDFRCPath,MRCP,MD, Syed Ashar Rais, Alison Bentley, Lynn Cawkwell, Peter Hillmen, MD PhD, Guy Pratt, James M. Allan
Journal: Blood
Blood (2019) 134 (Supplement_1): 1740.
https://doi.org/10.1182/blood-2019-122037
Published: 2019
Journal Articles

Cross-Talk between Cytokine and NF-ĸB Signaling in the CLL Microenvironment Can Affect Sensitivity for Venetoclax

Rachel Thijssen, Marco Haselager, Elaine Willmore, Simon Mackay, Arnon P. Kater, MD, Eric Eldering
Journal: Blood
Blood (2017) 130 (Supplement 1): 4306.
https://doi.org/10.1182/blood.V130.Suppl_1.4306.4306
Published: 2017
Journal Articles

Targeting Ikkα in CLL: Inhibition of Non-Canonical NF-κb Signaling Decreases Survival and Proliferation of CD40L-Stimulated Primary CLL Cells

Elaine Willmore, PhD, Aaron Gardner, PhD, Susan J Tudhope, PhD, Andrew Herridge, BSc, Jill Hunter, Jonathan P Wallis, MD, Helen J Marr, MD PhD, Giacomo Berretta, PhD, David Breen, PhD, Andrew Paul, PhD, Darren Edwards, PhD, Louise C Young, PhD, Colin J Suckling, PhD, Robin Plevin, PhD, Marie Boyd, PhD, James M Allan, DPhil, Simon Mackay, PhD, Neil D Perkins, PhD
Journal: Blood
Blood (2016) 128 (22): 3959.
https://doi.org/10.1182/blood.V128.22.3959.3959
Published: 2016
Journal Articles

The p53-MDM2 Antagonist RG7388 Activates p53 and Induces a Predominantly Pro-Apoptotic Gene Expression Signature in Chronic Lymphocytic Leukemia

Carmela Ciardullo, PhD, Laura Woodhouse, PhD, Erhan Aptullahoglu, MSc, Jonathan P Wallis, MD, Helen J Marr, MD PhD, Scott R Marshall, MD, Nick Bown, PhD, Elaine Willmore, PhD, John Lunec, PhD
Journal: Blood
Blood (2016) 128 (22): 893.
https://doi.org/10.1182/blood.V128.22.893.893
Published: 2016
Journal Articles

The Role of HOXA4 in Chronic Lymphocytic Leukaemia Progression and Response to Therapy

Timothy M Barrow, PhD, Laura Woodhouse, PhD, Gesa Junge, PhD, Susan J Tudhope, PhD, Charlotte Behardien, BSc, Jonathan P Wallis, MD, Helen J Marr, MD PhD, Scott R Marshall, MD, Nick Bown, PhD, Elaine Willmore, BSc, PhD, Gordon Strathdee, BSc, PhD
Journal: Blood
Blood (2016) 128 (22): 3924.
https://doi.org/10.1182/blood.V128.22.3924.3924
Published: 2016
Journal Articles

High Activity of Poly(ADP-Ribose) Polymerase in Chronic Lymphocytic Leukemia

Elaine Willmore, BSc, PhD, Natalie Rodrigues, Lisa Allinson, BSc, Geoffrey P Summerfield, MD, Jonathan Wallis, MD, Chris Lowe, Nicola Curtin, PhD
Journal: Blood
Blood (2012) 120 (21): 1788.
https://doi.org/10.1182/blood.V120.21.1788.1788
Published: 2012
Journal Articles

P B S-1086, a “Pan-Rel” Inhibitor, Decreases Viability of Chronic Lymphocytic Leukemia Cells

Susan J Tudhope, BSc, PhD, Evan A Mulligan, BSc, PhD, Jill E Hunter, BSc, PhD, Geoffrey P Summerfield, MD, Scott Marshall, MD, Jonathan Wallis, MD, Helen Marr, Paul Evans, Chris Lowe, Barbara W Durkacz, BSc, PhD, Jie Zhang, PhD, Jeffrey Meshulam, BS, Kathryn Bobb, MS, Elaine Willmore, BSc, PhD
Journal: Blood
Blood (2012) 120 (21): 867.
https://doi.org/10.1182/blood.V120.21.867.867
Published: 2012
Journal Articles

Relationships Between Aberrant Activity of the NF-κB Subunits and Outcome In Chronic Lymphocytic Leukemia: The Dual Role of DNA Damage Sensor Enzymes

Evan A Mulligan, Jill E Hunter, Arabella EG Baird, Sarah Elliott, Geoffrey P Summerfield, Karen Hamlen, Chris Lowe, Jonathan Wallis, Stephany Veuger, Barbara W Durkacz, Elaine Willmore
Journal: Blood
Blood (2010) 116 (21): 3588.
https://doi.org/10.1182/blood.V116.21.3588.3588
Published: 2010
Journal Articles

ATM Mutant Chronic Lymphocytic Leukaemia Cells are Chemosensitized by Inhibition of DNA-Dependent Protein Kinase

Elaine Willmore, BSc, PhD, Ana Skowronska, Evan A Mulligan, PhD, G. Ahmed, Sarah Elliott, PhD, Geoffrey P Summerfield, Karen Hamlen, Chris Lowe, Barbara W Durkacz, Tanja Stankovic
Journal: Blood
Blood (2010) 116 (21): 433.
https://doi.org/10.1182/blood.V116.21.433.433
Published: 2010
Journal Articles

DNA-Dependent Protein Kinase Is a Therapeutic Target in Poor Prognosis B-Cell Chronic Lymphocytic Leukemia

Elaine Willmore, BSc, PhD, Sarah L. Elliott, Clark J. Crawford, Geoffrey Summerfield, Tryfonia Mainou-Fowler, Graham Jackson, Paul Evans, Paula Newton, Duncan Gowans, Barbara W. Durkacz
Journal: Blood
Blood (2008) 112 (11): 382.
https://doi.org/10.1182/blood.V112.11.382.382
Published: 2008
Journal Articles

Targeting DNA-PK and ATM Increases Sensitivity to Chlorambucil and Fludarabine in Chemoresistant and p53-Defective B-CLL Cells.

Elaine Willmore, PhD, Geoffrey P. Summerfield, MD, Tryfonia Mainou-Fowler, PhD, Graham H. Jackson, MD, Anthony Carter, Andrew R. Pettitt, MD, Barbara W. Durkacz, PhD
Journal: Blood
Blood (2006) 108 (11): 523.
https://doi.org/10.1182/blood.V108.11.523.523
Published: 2006
Journal Articles

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia

Elaine Willmore, Sarah de Caux, Nicola J. Sunter, Michael J. Tilby, Graham H. Jackson, Caroline A. Austin, Barbara W. Durkacz
Journal: Blood
Blood (2004) 103 (12): 4659–4665.
https://doi.org/10.1182/blood-2003-07-2527
Published: 2004