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Journal Articles

Fructose Treatment Targets Myeloid Leukemogenesis in IDH2 Mutants By Exhausting Alpha-Ketoglutarate Pools

Angela Maria Savino, Briana Turner, Sangmoo Jeong, Tanya Schild, Xuejing Yang, Hanzhi Luo, Rachel Chirayil, Quinlan Cullen, Mandy Chan, Grace Han, Kathryn Chang, Sudha Janaki Raman, Justin R Cross, Kayvan Keshari, Michael G Kharas
Journal: Blood
Blood (2022) 140 (Supplement 1): 2966–2967.
https://doi.org/10.1182/blood-2022-164626
Published: 2022
Journal Articles

Pre-Clinical Efficacy of the Novel Kinase Inhibitor Nintedanib on PAX5 Fusion Genes in Pediatric Ph-like B-Cell Precursor Acute Lymphoblastic Leukemia

Grazia Fazio, Silvia Bresolin, Claudia Saitta, Daniela Silvestri, Elena Vendramini, Chiara Palmi, Silvia Rigamonti, Marta Galbiati, Manuel Quadri, Stefano Mecca, Angela Maria Savino, Michela Bardini, Andrea Grioni, Maria Grazia Valsecchi, PhD, Geertruy te Kronnie, Andrea Biondi, MD, Giovanni Cazzaniga, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 745.
https://doi.org/10.1182/blood-2019-128509
Published: 2019
Journal Articles

Stearoyl-CoA Desaturase (SCD) Enhances Central Nervous System Leukemia

Angela Maria Savino, PhD, Orianne Olivares, PhD, Shani Barel, Lev Yakimov, Ifat Geron, Hila Fishman, Inbal Mor, Ifat Abramovich, Sara Isabel Fernandes, Eyal Gottlieb, Christina Halsey, MD PhD, Shai Izraeli, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 389.
https://doi.org/10.1182/blood-2018-99-114749
Published: 2018
Journal Articles

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Ifat Geron, PhD, Angela Maria Savino, PhD, Noa Tal, MD PhD, John Brown, PhD, Virginia A Turati, DPhil, Yu Nee Lee, PhD, Chela James, PhD, Avigail Rein Gil, MD, Yehudit Birger, PhD, Inna Muler, Michal Hameiri, PhD, Victoria Marcu-Malina, PhD, Ute Fischer, PhD, Arndt Borkhardt, MD, Ilan M. Kirsch, MD, Arnon Nagler, MD, Tariq Enver, PhD, Shai Izraeli, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 566.
https://doi.org/10.1182/blood-2018-99-115913
Published: 2018
Journal Articles

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Angela Maria Savino, Jolanda Sarno, Luca Trentin, Margherita Vieri, Grazia Fazio, PhD, Michela Bardini, Cristina Bugarin, Gianluca Fossati, Kara L. Davis, DO, Giuseppe Gaipa, PhD, Lueder Hinrich Meyer, MD, Garry P. Nolan, Prof, PhD, Andrea Biondi, Prof, MD, Geertruy Te Kronnie, PhD, Chiara Palmi, PhD, Giovanni Cazzaniga
Journal: Blood
Blood (2015) 126 (23): 2534.
https://doi.org/10.1182/blood.V126.23.2534.2534
Published: 2015
Journal Articles

Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Jolanda Sarno, Kara L. Davis, DO, Angela Maria Savino, PhD, Cristina Bugarin, Stefania Pinto, Chiara Buracchi, PhD, Astraea Jager, BS, Chiara Palmi, PhD, Ruth C Barber, PhD, Daniela Silvestri, Gianni Cazzaniga, PhD, Martin J.S. Dyer, Prof., Andrea Biondi, Prof, MD, Garry P. Nolan, Prof, PhD, Giuseppe Gaipa, PhD
Journal: Blood
Blood (2015) 126 (23): 906.
https://doi.org/10.1182/blood.V126.23.906.906
Published: 2015
Journal Articles

Autosomal dominant macrothrombocytopenia in Italy is most frequently a type of heterozygous Bernard-Soulier syndrome

Anna Savoia, Carlo L. Balduini, Maria Savino, Patrizia Noris, Maria Del Vecchio, Silverio Perrotta, Simona Belletti, Vincenzo Poggi, Achille Iolascon
Journal: Blood
Blood (2001) 97 (5): 1330–1335.
https://doi.org/10.1182/blood.V97.5.1330
Published: 2001