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Journal Articles

Loss of CD62L Expression in CD4+FoxP3+ Regulatory T Cells Following Freeze-and-Thaw Prevents Protection Against GVHD in Murine Models

Mareike Florek, MD, Dominik Schneidawind, MD, Jeanette Baker, PhD, Antonio Pierini, MD, Dennis B Leveson-Gower, PhD, Yuqiong Pan, MD, Robert S. Negrin, MD, Everett H. Meyer, MD PhD

Blood (2014) 124 (21): 2427.

https://doi.org/10.1182/blood.V124.21.2427.2427

Published: 2014

Journal Articles

CD4+FoxP3+ Regulatory T Cells Regulate B Cell Differentiation and Induce Tolerance to Bone Marrow Grafts

Antonio Pierini, MD, Hidekazu Nishikii, MD PhD, Yuqiong Pan, MD, Jeanette Baker, PhD, Dennis B Leveson-Gower, PhD, Mareike Florek, MD, Robert Negrin, MD

Blood (2014) 124 (21): 4322.

https://doi.org/10.1182/blood.V124.21.4322.4322

Published: 2014

Journal Articles

Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models

Mareike Florek, Emanuela I. Sega, Dennis B. Leveson-Gower, Jeanette Baker, Antonia M. S. Müller, Dominik Schneidawind, Everett Meyer, Robert S. Negrin

Blood (2014) 124 (11): 1832–1842.

https://doi.org/10.1182/blood-2014-02-555128

Published: 2014

Includes: Supplemental data

Journal Articles

Donor hematopoiesis in mice following total lymphoid irradiation requires host T-regulatory cells for durable engraftment

Antonia M. S. Müller, Jessica Poyser, Natascha J. Küpper, Cassandra Burnett, Rose M. Ko, Holbrook E.K. Kohrt, Mareike Florek, Pei Zhang, Robert S. Negrin, Judith A. Shizuru

Blood (2014) 123 (18): 2882–2892.

https://doi.org/10.1182/blood-2013-10-530212

Published: 2014

Includes: Supplemental data

Journal Articles

Mast cells suppress murine GVHD in a mechanism independent of CD4 + CD25 + regulatory T cells

Dennis B. Leveson-Gower, Emanuela I. Sega, Janet Kalesnikoff, Mareike Florek, Yuqiong Pan, Antonio Pierini, Stephen J. Galli, Robert S. Negrin

Blood (2013) 122 (22): 3659–3665.

https://doi.org/10.1182/blood-2013-08-519157

Published: 2013

Includes: Supplemental data

Journal Articles

In Allogeneic Transplant Recipients Th17 Cells Originate From Donor Stem Cells and Reside In Target Organs of Chronic Graft-Versus-Host Disease

Antonia MS Mueller, MD, Mareike Florek, MD, Natascha J Kuepper, Jessica Poyser, Judith A. Shizuru, MD, PhD

Blood (2013) 122 (21): 5425.

https://doi.org/10.1182/blood.V122.21.5425.5425

Published: 2013

Journal Articles

Host CD4+CD25+FoxP3+ Regulatory T Cells Facilitate Donor Engraftment Without Impacting Graft Versus Host Disease Onset After Major-Mismatched Hematopoietic Stem Cell Transplantation

Antonio Pierini, MD, Hidekazu Nishikii, MD, PhD, Mareike Florek, MD, Dennis B Leveson-Gower, PhD, Yuqiong Pan, MD, Byung-Su Kim, MD, Jeanette Baker, PhD, Robert Negrin, MD

Blood (2013) 122 (21): 1996.

https://doi.org/10.1182/blood.V122.21.1996.1996

Published: 2013

Journal Articles

Adoptive Transfer Of Ex Vivo “Educated” CD4+CD25+FoxP3+ Regulatory T Cells Effectively Treats Acute Graft Versus Host Disease Preserving Graft Versus Tumor Effect

Antonio Pierini, MD, Dominik Schneidawind, MD, Mareike Florek, MD, Maite Alvarez, PhD, Yuqiong Pan, MD, Jeanette Baker, PhD, Everett Meyer, MD, PhD, Robert Negrin, MD

Blood (2013) 122 (21): 4485.

https://doi.org/10.1182/blood.V122.21.4485.4485

Published: 2013

Journal Articles

A distinct evolution of the T-cell repertoire categorizes treatment refractory gastrointestinal acute graft-versus-host disease

Everett H. Meyer, Andro R. Hsu, Joanna Liliental, Andrea Löhr, Mareike Florek, James L. Zehnder, Sam Strober, Philip Lavori, David B. Miklos, David S. Johnson, Robert S. Negrin

Blood (2013) 121 (24): 4955–4962.

https://doi.org/10.1182/blood-2013-03-489757

Published: 2013

Includes: Supplemental data

Journal Articles

Immune Injury by Allogeneic CD4 + T Cells Leads to Host Hematopoietic Stem Cell Dormancy and Prevents Engraftment of Donor Cells.

Antonia MS Mueller, MD, Mareike Florek, MD, Holbrook E Kohrt, MD, PhD, Judith A. Shizuru, MD, PhD

Blood (2012) 120 (21): 2366.

https://doi.org/10.1182/blood.V120.21.2366.2366

Published: 2012

Journal Articles

The Expansion of Gastrointestinal-associated αβ T Cell Clones in Peripheral Blood Over Time Is a Disease Feature of Severe Acute Graft-Versus-Host Disease

Everett H. Meyer, MD, PhD, Joanna Liliental, PhD, Mareike Florek, MD, Andrea Löhr, PhD, Andro Hsu, PhD, David Scott Johnson, PhD, David B Miklos, MD, PhD, James L. Zehnder, Robert S. Negrin, MD

Blood (2012) 120 (21): 228.

https://doi.org/10.1182/blood.V120.21.228.228

Published: 2012

Journal Articles

Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells

Saar Gill, Adrianne E. Vasey, Alysha De Souza, Jeanette Baker, Aaron T. Smith, Holbrook E. Kohrt, Mareike Florek, Kenneth D. Gibbs, Jr, Keri Tate, David S. Ritchie, Robert S. Negrin

Blood (2012) 119 (24): 5758–5768.

https://doi.org/10.1182/blood-2012-03-415364

Published: 2012

Includes: Supplemental data

Journal Articles

The Inhibitory Receptor LAG-3 Is Not Essential for Regulatory T Cells Function but Influences Donor T Cell Potency in Acute Graft-Versus-Host-Disease

Emanuela I Sega, PhD, Dennis B Leveson-Gower, PhD, Mareike Florek, MD, Robert S Negrin, MD

Blood (2011) 118 (21): 1900.

https://doi.org/10.1182/blood.V118.21.1900.1900

Published: 2011

Journal Articles

A Novel Model of Pre-Emptive ECP Treatment Shows Significant Reduction of Gvhd-Related Mortality In Mice,

Mareike Florek, MD, Emanuela I Sega, PhD, Antonia MS Mueller, MD, Dennis B Leveson-Gower, PhD, Judith A Shizuru, MD PhD, Robert S Negrin, MD

Blood (2011) 118 (21): 4025.

https://doi.org/10.1182/blood.V118.21.4025.4025

Published: 2011

Journal Articles

Graft T Cells Retard Stem Cell Derived Lymphoid Organ Reconstitution and Immune Function After Allogeneic Transplantation,

Antonia MS Mueller, MD, Holbrook E Kohrt, MD, Sumana Shashidhar, Mareike Florek, MD, Natascha J Kuepper, Janice (Wes) M. Brown, MD, Judith A Shizuru, MD PhD

Blood (2011) 118 (21): 4030.

https://doi.org/10.1182/blood.V118.21.4030.4030

Published: 2011

Journal Articles

IL-17 Gene Ablation Does Not Impact Treg-Mediated Suppression of Graft-Versus-Host Disease Following Bone Marrow Transplantation,

Lucrezia Colonna, PhD, Mareike Florek, MD, Dennis B Leveson-Gower, PhD, Emanuela I Sega, PhD, Robert Zeiser, M.D., Martin Buess, MD, Robert S Negrin, MD

Blood (2011) 118 (21): 4037.

https://doi.org/10.1182/blood.V118.21.4037.4037

Published: 2011

Journal Articles

Natural Killer Cell Adoptive Immunotherapy Is Hampered by A Rapid Development of NK Cell Dysfunction Characterized by Loss of Effector Mechanisms and Downregulation of the Transcription Factors T-Bet and Eomesodermin; Definition and Possible Mechanism of NK Cell Exhaustion

Saar I. Gill, MBBS, FRACP, Adrianne E Vasey, BS, Jeanette B Baker, PhD, Aaron Smith, BS, Holbrook E Kohrt, MD, Mareike Florek, MD, David Ritchie, MBBS, FRACP, FRCPA, PhD, Robert S Negrin, MD

Blood (2011) 118 (21): 1000.

https://doi.org/10.1182/blood.V118.21.1000.1000

Published: 2011

Journal Articles

Interactions Between Donor CD4 Cells and Residual Host Cells After Nonmyeloablative Hematopoietic Stem Cell Transplantation Suppress Hematopoiesis and Lead to Graft Rejection

Antonia MS Mueller, Mareike Florek, Husein Hadeiba, Judith A Shizuru

Blood (2010) 116 (21): 75.

https://doi.org/10.1182/blood.V116.21.75.75

Published: 2010

Journal Articles

Mast Cells Reduce Gvhd Severity In Allogeneic Transplantation by Reducing the Proliferation of Conventional T Cells

Dennis B Leveson-Gower, Emanuela I Sega, Janet Kalesnikoff, Mareike Florek, Stephen J Galli, Robert Negrin, MD

Blood (2010) 116 (21): 243.

https://doi.org/10.1182/blood.V116.21.243.243

Published: 2010

Journal Articles

Engraftment Failure After Non-Myeloablative Hematopoietic Stem Cell Transplantation: Donor CD4 Cells Interfere with Residual Host Cells and Can Trigger Rejection of the Graft.

Antonia MS Mueller, Mareike Florek, Judith Shizuru

Blood (2009) 114 (22): 3528.

https://doi.org/10.1182/blood.V114.22.3528.3528

Published: 2009

NARROW

Loss of CD62L Expression in CD4+FoxP3+ Regulatory T Cells Following Freeze-and-Thaw Prevents Protection Against GVHD in Murine Models

CD4+FoxP3+ Regulatory T Cells Regulate B Cell Differentiation and Induce Tolerance to Bone Marrow Grafts

Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models

Donor hematopoiesis in mice following total lymphoid irradiation requires host T-regulatory cells for durable engraftment

Mast cells suppress murine GVHD in a mechanism independent of CD4 + CD25 + regulatory T cells

In Allogeneic Transplant Recipients Th17 Cells Originate From Donor Stem Cells and Reside In Target Organs of Chronic Graft-Versus-Host Disease

Host CD4+CD25+FoxP3+ Regulatory T Cells Facilitate Donor Engraftment Without Impacting Graft Versus Host Disease Onset After Major-Mismatched Hematopoietic Stem Cell Transplantation

Adoptive Transfer Of Ex Vivo “Educated” CD4+CD25+FoxP3+ Regulatory T Cells Effectively Treats Acute Graft Versus Host Disease Preserving Graft Versus Tumor Effect

A distinct evolution of the T-cell repertoire categorizes treatment refractory gastrointestinal acute graft-versus-host disease

Immune Injury by Allogeneic CD4 + T Cells Leads to Host Hematopoietic Stem Cell Dormancy and Prevents Engraftment of Donor Cells.

The Expansion of Gastrointestinal-associated αβ T Cell Clones in Peripheral Blood Over Time Is a Disease Feature of Severe Acute Graft-Versus-Host Disease

Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells

The Inhibitory Receptor LAG-3 Is Not Essential for Regulatory T Cells Function but Influences Donor T Cell Potency in Acute Graft-Versus-Host-Disease

A Novel Model of Pre-Emptive ECP Treatment Shows Significant Reduction of Gvhd-Related Mortality In Mice,

Graft T Cells Retard Stem Cell Derived Lymphoid Organ Reconstitution and Immune Function After Allogeneic Transplantation,

IL-17 Gene Ablation Does Not Impact Treg-Mediated Suppression of Graft-Versus-Host Disease Following Bone Marrow Transplantation,

Natural Killer Cell Adoptive Immunotherapy Is Hampered by A Rapid Development of NK Cell Dysfunction Characterized by Loss of Effector Mechanisms and Downregulation of the Transcription Factors T-Bet and Eomesodermin; Definition and Possible Mechanism of NK Cell Exhaustion

Interactions Between Donor CD4 Cells and Residual Host Cells After Nonmyeloablative Hematopoietic Stem Cell Transplantation Suppress Hematopoiesis and Lead to Graft Rejection

Mast Cells Reduce Gvhd Severity In Allogeneic Transplantation by Reducing the Proliferation of Conventional T Cells

Engraftment Failure After Non-Myeloablative Hematopoietic Stem Cell Transplantation: Donor CD4 Cells Interfere with Residual Host Cells and Can Trigger Rejection of the Graft.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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