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Journal Articles

Decoding the Pivotal Roles of BCL10 Activating Mutations in DLBCL Drug Resistance and Lymphomagenesis

Caroline A. Coughlin, Dhanvantri Chahar, Marianna Lekakis, Hsuan-Ting Huang, Abdessamad Youssfi Alaoui, Lingxiao Li, Evan Roberts, Natalia Campos Gallego, Claude-Henry Volmar, Ola Landgren, Shaun Brothers, Anthony Griswold, Catalina Amador, Daniel Bilbao, Francesco Maura, Jonathan H. Schatz

Blood (2024) 144 (Supplement 1): 829.

https://doi.org/10.1182/blood-2024-203545

Published: 2024

Journal Articles

The Cyclin-G Associated Kinase (GAK) Is a Critical Targetable Dependency for Successful Mitosis By Diffuse Large B-Cell Lymphomas Linked to Retinoblastoma Loss of Function

Olivia Barbara Lightfuss, Preet Kumar, Austin Daniel Newsam, Lingxiao Li, Pierre A. Younes, Toral Shastri, Abdessamad Youssfi Alaoui, Diego E. Hernandez Parets, Paola Manara, Daniel Bilbao, Stephan Schürer, Vance P. Lemmon, Francesco Maura, Yangbo Feng, Hassan A. Ali, Jonathan H. Schatz

Blood (2024) 144 (Supplement 1): 2781.

https://doi.org/10.1182/blood-2024-206073

Published: 2024

Journal Articles

The Cyclin-G Associated Kinase (GAK) Is a Critical Dependency for Cell-Cycle Progression in Diffuse Large B-Cell Lymphoma Associated with Deregulation of the Retinoblastoma Tumor Suppressor

Austin D. Newsam, Preet Kumar, Olivia B. Lightfuss, Lingxiao Li, Anirban Ghoshal, Stephan Schürer, Vance Lemmon, Yangbo Feng, Hassan Al-Ali, Jonathan H. Schatz

Blood (2022) 140 (Supplement 1): 2261–2262.

https://doi.org/10.1182/blood-2022-164697

Published: 2022

Journal Articles

PI3K/AKT Activation Mediates B-Cell Transformation By the "T" Splice-Variant of Fyn Kinase

Preet Kumar, Lingxiao Li, Jonathan H. Schatz

Blood (2021) 138 (Supplement 1): 4334.

https://doi.org/10.1182/blood-2021-153053

Published: 2021

Journal Articles

Targeted Delivery of Nanocarrier-Conjugated Doxorubicin to Widen the Therapeutic Window of the Most Active Drug in Lymphoma Therapeutics

Artavazd Arumov, BSc, Piumi Y. Liyanage, BS, Asaad Trabolsi, MD, Lingxiao Li, PhD, Evan R. Roberts, BS, Daniel Bilbao, PhD, Roger M. LeBlanc, PhD, Jonathan H. Schatz, MD

Blood (2019) 134 (Supplement_1): 4061.

https://doi.org/10.1182/blood-2019-122599

Published: 2019

Journal Articles

NPM-ALK Upregulates Jab1/Csn5 through STAT3 Activation in Anaplastic Large Cell Lymphoma: A Novel Function of NPM-ALK That Contributes to PD1/PD-L1 Immune Checkpoint Regulation

Elias Drakos, MD PhD Prof., Konstantina Stathopoulou, MSc., Lingxiao Li, PhD, Daniel Bilbao, Vasiliki Leventaki, Pedro Farrajota Neves Da Silva, MD, Vasileios Atsaves, PhD, Anders Österborg, MD PhD, L. Jeffrey Medeiros, MD, Francisco Vega, MD PhD, Jonathan H. Schatz, MD, Francois Claret, PhD, George Z. Rassidakis, MD PhD Prof.

Blood (2019) 134 (Supplement_1): 2796.

https://doi.org/10.1182/blood-2019-130457

Published: 2019

Journal Articles

CRISPR/Cas9 Generation of Npm1-Alk in Transplantable Murine Hematopoietic Stem Cells Accurately Models ALK-Positive Lymphoma in Recipients

Soumya Sundara Rajan, MSc, Lingxiao Li, PhD, Kranthi Kunkalla, Amit Dipak Amin, PhD, Nitin Agarwal, Francisco Vega, MD PhD, Jonathan H. Schatz, MD

Blood (2018) 132 (Supplement 1): 779.

https://doi.org/10.1182/blood-2018-99-114692

Published: 2018

Journal Articles

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Blood (2018) 131 (3): 328–341.

https://doi.org/10.1182/blood-2017-06-789669

Published: 2018

Includes: Supplemental data

Journal Articles

The Marine Natural Compound Elatol Is a Novel Protein Translation Inhibitor with Potent Activity Against Aggressive Non-Hodgkin Lymphomas

Tara Peters, BA, Joseph Tillotson, PhD, Sarah C Wilmore, BSc, Alison Yeomans, PhD, Graham Packham, PhD, Eli Chapman, PhD, Jonathan H. Schatz, MD, Lingxiao Li, PhD

Blood (2017) 130 (Supplement 1): 4112.

https://doi.org/10.1182/blood.V130.Suppl_1.4112.4112

Published: 2017

Journal Articles

NPM1-ALK Overexpression-Driven Toxicity in ALCL Is Partner Dependent and Mediated By STAT1 Antagonism of STAT3 Survival Signaling, Revealing a Novel Therapeutic Strategy

Soumya Sundara Rajan, M.Sc, Amit Dipak Amin, PhD, Lingxiao Li, PhD, Delphine C. M. Rolland, PharmD, PhD, Haiquan Li, PhD, Soham Puvvada, MD, Yves Lussier, MD, Megan S. Lim, MDPhD, Jonathan H. Schatz, MD

Blood (2017) 130 (Supplement 1): 2506.

https://doi.org/10.1182/blood.V130.Suppl_1.2506.2506

Published: 2017

Journal Articles

Activated B-Cell DLBCL with Downstream Activation of Survival Signaling Requires PIM Kinase Activity to Maintain Oncoprotein Translation

Tara L. Peters, BA, Ana A Tula-Sanchez, PhD, Lingxiao Li, PhD, Praechompoo Pongtornpipat, BS, Mengdie WANG, BS, Nicolette BROWN, BS, Soham D. Puvvada, MD, Jonathan H. Schatz, MD

Blood (2014) 124 (21): 4496.

https://doi.org/10.1182/blood.V124.21.4496.4496

Published: 2014

Journal Articles

Potent Efficacy of BCL2 Inhibition with ABT-199 in High-Risk Aggressive B-Lymphoma Models When Combined with Knockdown of MCL1

Lingxiao Li, PhD, Praechompoo Pongtornpipat, BS, Timothy Tiutan, BS, BA, Samantha L. Kendrick, PhD, Soyoung Park, MD, Daniel O Persky, MD, Lisa M. Rimsza, MD, Soham D. Puvvada, MD, Jonathan H. Schatz, MD

Blood (2014) 124 (21): 506.

https://doi.org/10.1182/blood.V124.21.506.506

Published: 2014

Journal Articles

Targeting MYC Expression With CDK Inhibitors Shows Potency In Preclinical Models Of High-Risk Diffuse Large B-Cell Lymphom

Lingxiao Li, PhD, Praechompoo Pongtornpipat, Soham D. Puvvada, MD, Jonathan H. Schatz, MD

Blood (2013) 122 (21): 1831.

https://doi.org/10.1182/blood.V122.21.1831.1831

Published: 2013

NARROW

Decoding the Pivotal Roles of BCL10 Activating Mutations in DLBCL Drug Resistance and Lymphomagenesis

The Cyclin-G Associated Kinase (GAK) Is a Critical Targetable Dependency for Successful Mitosis By Diffuse Large B-Cell Lymphomas Linked to Retinoblastoma Loss of Function

The Cyclin-G Associated Kinase (GAK) Is a Critical Dependency for Cell-Cycle Progression in Diffuse Large B-Cell Lymphoma Associated with Deregulation of the Retinoblastoma Tumor Suppressor

PI3K/AKT Activation Mediates B-Cell Transformation By the "T" Splice-Variant of Fyn Kinase

Targeted Delivery of Nanocarrier-Conjugated Doxorubicin to Widen the Therapeutic Window of the Most Active Drug in Lymphoma Therapeutics

NPM-ALK Upregulates Jab1/Csn5 through STAT3 Activation in Anaplastic Large Cell Lymphoma: A Novel Function of NPM-ALK That Contributes to PD1/PD-L1 Immune Checkpoint Regulation

CRISPR/Cas9 Generation of Npm1-Alk in Transplantable Murine Hematopoietic Stem Cells Accurately Models ALK-Positive Lymphoma in Recipients

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

The Marine Natural Compound Elatol Is a Novel Protein Translation Inhibitor with Potent Activity Against Aggressive Non-Hodgkin Lymphomas

NPM1-ALK Overexpression-Driven Toxicity in ALCL Is Partner Dependent and Mediated By STAT1 Antagonism of STAT3 Survival Signaling, Revealing a Novel Therapeutic Strategy

Activated B-Cell DLBCL with Downstream Activation of Survival Signaling Requires PIM Kinase Activity to Maintain Oncoprotein Translation

Potent Efficacy of BCL2 Inhibition with ABT-199 in High-Risk Aggressive B-Lymphoma Models When Combined with Knockdown of MCL1

Targeting MYC Expression With CDK Inhibitors Shows Potency In Preclinical Models Of High-Risk Diffuse Large B-Cell Lymphom

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American Society of Hematology

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American Society of Hematology

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