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Paola Manara
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Journal Articles

The Cyclin-G Associated Kinase (GAK) Is a Critical Targetable Dependency for Successful Mitosis By Diffuse Large B-Cell Lymphomas Linked to Retinoblastoma Loss of Function

Olivia Barbara Lightfuss, Preet Kumar, Austin Daniel Newsam, Lingxiao Li, Pierre A. Younes, Toral Shastri, Abdessamad Youssfi Alaoui, Diego E. Hernandez Parets, Paola Manara, Daniel Bilbao, Stephan Schürer, Vance P. Lemmon, Francesco Maura, Yangbo Feng, Hassan A. Ali, Jonathan H. Schatz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2781.
https://doi.org/10.1182/blood-2024-206073
Published: 2024
Journal Articles

Translational Disruption of NRF2 By Zotatifin Enhances Sensitivity to Ferroptosis and CAR-T Cells in Diffuse Large B-Cell Lymphoma

Paola Manara, Venu Venkatarame Gowda Saralamma, Austin Daniel Newsam, Marco Vincenzo Russo, Tyler Andrew Cunningham, Alicia Bilbao Martinez, Nikolai Fattakhov, Kyle Hoffman, Alexandra Marie Carbone, Abdessamad Youssfi Alaoui, Dhanvantri Chahar, Olivia Barbara Lightfuss, Francesco Maura, Daniel Bilbao, Jonathan H. Schatz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4167.
https://doi.org/10.1182/blood-2024-203442
Published: 2024
Journal Articles

Enhanced Ferroptosis Induction Susceptibility in Diffuse Large B-Cell Lymphoma through Rocaglate-Mediated Translation Inhibition

Paola Manara, Alexa Barroso, Abdessamad Youssfi Alaoui, Tyler A Cunningham, David H. Ho, Kyle Hoffman, Jonathan H. Schatz
Journal: Blood
Blood (2023) 142 (Supplement 1): 2814.
https://doi.org/10.1182/blood-2023-187443
Published: 2023
Journal Articles

The Marine Product Elatol Is a Novel Inhibitor of Mitochondrial Translation Triggering the Integrated Stress Response and Apoptosis in Leukemia and Lymphoma Cells

Tyler A. Cunningham, Priyanka Maiti, Paola Manara, Vivek Singh, Nigel Beaton, Alexey Amunts, Flavia Fontanesi, Antonio Barrientos, Jonathan H. Schatz
Journal: Blood
Blood (2022) 140 (Supplement 1): 7819.
https://doi.org/10.1182/blood-2022-166899
Published: 2022
Journal Articles

Translatome Reprogramming By Rocaglates in Lymphoma Induces Drug Resistance through up-Regulation of CD98hc, Activating Downstream AKT Survival Signaling

Paola Manara, Tyler A. Cunningham, J.J. David Ho, Caroline A. Coughlin, Jonathan H. Schatz
Journal: Blood
Blood (2022) 140 (Supplement 1): 8844.
https://doi.org/10.1182/blood-2022-166771
Published: 2022