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Journal Articles

Sonrotoclax overcomes BCL2 G101V mutation–induced venetoclax resistance in preclinical models of hematologic malignancy

Jiuyang Liu, Shuran Li, Qin Wang, Yingcai Feng, Haimei Xing, Xuefei Yang, Ying Guo, Yunhang Guo, Hanzi Sun, Xiaoxin Liu, Shasha Yang, Zhu Mei, Yutong Zhu, Zhenzhen Cheng, Shuaishuai Chen, Min Xu, Wenjing Zhang, Nanyan Wan, Jia Wang, Yanwen Ma, Shuo Zhang, Xudong Luan, Aiying Xu, Lin Li, Haitao Wang, Xiaolong Yang, Yuan Hong, Hai Xue, Xi Yuan, Nan Hu, Xiaomin Song, Zhiwei Wang, Xuesong Liu, Lai Wang, Ye Liu
Journal: Blood
Blood (2024) 143 (18): 1825–1836.
https://doi.org/10.1182/blood.2023019706
Published: 2024
Includes: Supplemental data
Journal Articles

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Ganqian Zhu, PhD, Huacheng Luo, Shi Chen, Qian Lai, Ying Guo, Olga A Guryanova, MDPhD, Yi Qiu, Feng-Chun Yang, MD PhD, Wei Li, Stephen D. Nimer, MD, Suming Huang, Mingjiang Xu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 886.
https://doi.org/10.1182/blood-2018-99-112232
Published: 2018
Journal Articles

Activation of Hottip lncrna Perturbs HSC Function Leading to AML like Disease in Mice

Huacheng Luo, Ganqian Zhu, PhD, Jie Zha, MD, Bowen Yan, Ph. D, Ying Guo, Jianfeng Xu, PhD, Qian Lai, Bing Xu, MD PhD, Feng-Chun Yang, MD PhD, Wei Li, Yi Qiu, Mingjiang Xu, MD PhD, Suming Huang
Journal: Blood
Blood (2018) 132 (Supplement 1): 3877.
https://doi.org/10.1182/blood-2018-99-110218
Published: 2018
Journal Articles

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Hui Yang, Stefan Kurtenbach, Ying Guo, Ines Lohse, Michael A. Durante, Jianping Li, Zhaomin Li, Hassan Al-Ali, Lingxiao Li, Zizhen Chen, Matthew G. Field, Peng Zhang, Shi Chen, Shohei Yamamoto, Zhuo Li, Yuan Zhou, Stephen D. Nimer, J. William Harbour, Claes Wahlestedt, Mingjiang Xu, Feng-Chun Yang
Journal: Blood
Blood (2018) 131 (3): 328–341.
https://doi.org/10.1182/blood-2017-06-789669
Published: 2018
Includes: Supplemental data
Journal Articles

Gain-of-Function of ASXL1 Truncating Protein in the Pathogenesis of Myeloid Malignancies

Hui Yang, PhD, Stefan Kurtenbach, PhD, Ying Guo, MD PhD, Ines Lohse, PhD, Michael Durante, PhD candidate, Peng Zhang, PhD, Yuan Zhou, PhD, William Harbour, MDPhD, Claes Wahlestedt, Mingjiang Xu, MDPhD, Feng-Chun Yang, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 564.
https://doi.org/10.1182/blood.V130.Suppl_1.564.564
Published: 2017
Journal Articles

Loss of ASXL1 in the Bone Marrow Niche Dysregulates Hematopoietic Stem Cell Fates through RNA Polymerase II Complex

Peng Zhang, PhD, Zizhen Chen, PhD, Rong Li, PhD, Ying Guo, MD PhD, Mingjiang Xu, MDPhD, Yuan Zhou, PhD, Feng-Chun Yang, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 133.
https://doi.org/10.1182/blood.V130.Suppl_1.133.133
Published: 2017
Journal Articles

Exposure-Response of Idelalisib Administered in Combination with Ofatumumab for the Treatment of Relapsed Chronic Lymphocytic Leukemia

Shringi Sharma, PhD, Ying Guo, PhD, Feng Jin, PhD, Xiaoming Li, PhD, Ronald L. Dubowy, MD, Terry Newcomb, PhD, Srini Ramanathan, PhD
Journal: Blood
Blood (2015) 126 (23): 4172.
https://doi.org/10.1182/blood.V126.23.4172.4172
Published: 2015
Journal Articles

Analysis of Clinical and Pathological Features of 117 Chinese Cases of Natural Killer/T Cell Lymphoma

Rong Liang, PhD, MD, Zhe Wang, PhD, MD, Qun xie Chen, PhD, MD, Xian qing Bai, PhD, MD, Guo qing Yan, PhD, MD, Lan Yang, MD, Tao Zhang, PhD, MD, Ying Guo, PhD, MD, Luhua Wang, M.D.
Journal: Blood
Blood (2012) 120 (21): 5105.
https://doi.org/10.1182/blood.V120.21.5105.5105
Published: 2012
Journal Articles

Effect of Huangqi On Mesenchymal Stem Cells (MSC) Transplanted Therapy in Spinal Cord Injury: It Promotes the Neural Differentiation of MSC In Vivo.

Qin Yu, Yueshuang Bai, Jie Lin, Lixian Sheng, Qin Dong, Ying Guo, Xiaobo Xuan
Journal: Blood
Blood (2009) 114 (22): 4476.
https://doi.org/10.1182/blood.V114.22.4476.4476
Published: 2009
Journal Articles

Molecular Mechanisms of Spindle Checkpoint-Apoptosis Linkage and Karyotypic Stability in Stem Cells.

Charlie Mantel, Sara Rhorabough, Ying Guo, Man-Ryul Lee, Myung-Kwan Han, Kye-Seong Kim, Hal E. Broxmeyer
Journal: Blood
Blood (2007) 110 (11): 3361.
https://doi.org/10.1182/blood.V110.11.3361.3361
Published: 2007
Journal Articles

Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability

Charlie Mantel, Ying Guo, Man Ryul Lee, Min-Kyoung Kim, Myung-Kwan Han, Hirohiko Shibayama, Seiji Fukuda, Mervin C. Yoder, Louis M. Pelus, Kye-Seong Kim, Hal E. Broxmeyer
Journal: Blood
Blood (2007) 109 (10): 4518–4527.
https://doi.org/10.1182/blood-2006-10-054247
Published: 2007
Includes: Supplemental data
Journal Articles

CD10 − MUM1 + follicular lymphoma lacks BCL2 gene translocation and shows characteristic biologic and clinical features

Clinical Trials & Observations Brief Report
Kennosuke Karube, Ying Guo, Junji Suzumiya, Yasuo Sugita, Yuko Nomura, Kohei Yamamoto, Kei Shimizu, Shirou Yoshida, Hideki Komatani, Morishige Takeshita, Masahiro Kikuchi, Naoya Nakamura, Osamu Takasu, Fumiko Arakawa, Hiroyuki Tagawa, Masao Seto, Koichi Ohshima
Journal: Blood
Blood (2006) 109 (7): 3076–3079.
https://doi.org/10.1182/blood-2006-09-045989
Published: 2006
Includes: Supplemental data
Journal Articles

Oct-4 Is Crucial for Stress-Induced Murine Embryonic Stem Cell Survival/Anti-Apoptosis Mediated by STAT3/Survivin.

Ying Guo, MD, MS, Charlie Mantel, B.S., Robert A. Hromas, M.D., Hal E. Broxmeyer, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 277.
https://doi.org/10.1182/blood.V108.11.277.277
Published: 2006
Journal Articles

Oct-4 Is Crucial for Murine Embryonic Stem Cell Secretion of Cytokines/Growth Modulators That Enhance Cell Survival/Anti-Apoptosis of Murine ES Cells and Bone Marrow Hematopoietic Progenitor Cells.

Ying Guo, MD, Barbara Graham-Evans, PhD, Charlie R. Mantal, Robert A. Hromas, M.D, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2005) 106 (11): 1359.
https://doi.org/10.1182/blood.V106.11.1359.1359
Published: 2005
Journal Articles

Role of SIRT1 in Proliferation and Self-Renewal of Mouse Embryonic Stem Cells.

Myung-Kwan Han, Charlie Mantel, Ying Guo, Wen Tao, Hal E. Broxmeyer
Journal: Blood
Blood (2005) 106 (11): 520.
https://doi.org/10.1182/blood.V106.11.520.520
Published: 2005
Journal Articles

oct-4 Is Essential for Aneuploidy/Polyploidy-Tolerance in Embryonic Stem (ES) Cells and the Fate of Tetraploid ES Cells during Early Differentiation.

Charlie R. Mantel, Ying Guo, Myung-Kwan Han, Sara Roharbaugh, Barbara Graham-Evans, Mervin C. Yoder, Robert A. Hromas, Hal E. Broxmeyer
Journal: Blood
Blood (2005) 106 (11): 311.
https://doi.org/10.1182/blood.V106.11.311.311
Published: 2005
Journal Articles

Checkpoint Adaptation and Apoptosis Are Uncoupled in Mouse ES Cell Lines.

Charlie Mantel, Ying Guo, Hirohiko Shibayama, Seiji Fukuda, Mervin C. Yoder, Louis M. Pelus, Hal E. Broxmeyer
Journal: Blood
Blood (2004) 104 (11): 1259.
https://doi.org/10.1182/blood.V104.11.1259.1259
Published: 2004
Journal Articles

SDF-1/CXCL12 Enhances Survival of Murine Embryonic Stem Cells and Their Production of Myeloid Progenitors, but Not Hemangioblasts.

Ying Guo, M.D, Giao Hangoc, Ph.D., Huimin Bian, Louis M. Pelus, Ph.D., Hal E. Broxmeyer, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 1693.
https://doi.org/10.1182/blood.V104.11.1693.1693
Published: 2004
Journal Articles

The homeoprotein Hex is required for hemangioblast differentiation

Ying Guo, Rebecca Chan, Heather Ramsey, Weiming Li, Xiaodong Xie, William C. Shelley, Juan Pedro Martinez-Barbera, Bernardo Bort, Kenneth Zaret, Mervin Yoder, Robert Hromas
Journal: Blood
Blood (2003) 102 (7): 2428–2435.
https://doi.org/10.1182/blood-2003-02-0634
Published: 2003