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Lawrence J Breyfogle
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Journal Articles

Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms

Edwin Chen, Rebekka K. Schneider, Lawrence J. Breyfogle, Emily A. Rosen, Luke Poveromo, Shannon Elf, Amy Ko, Kristina Brumme, Ross Levine, Benjamin L. Ebert, Ann Mullally
Journal: Blood
Blood (2015) 125 (2): 327–335.
https://doi.org/10.1182/blood-2014-04-567024
Published: 2015
Includes: Supplemental data
Journal Articles

The Recql5 Helicase Is a Novel Downstream Target of Jak2V617F and Maintains Genome Stability in Response to Replication Stress

Edwin Chen, PhD, Jong-Sook Ahn, PhD, Lawrence J Breyfogle, Anthony R Green, PhDFRCP FRCPath, Benjamin L. Ebert, MDPhD, Ann Mullally, MD
Journal: Blood
Blood (2014) 124 (21): 822.
https://doi.org/10.1182/blood.V124.21.822.822
Published: 2014
Journal Articles

Tet2 Loss Accelerates The Myeloproliferative Neoplasm (MPN) Phenotype Of Jak2V617F Knockin Mice But Is Insufficient To Cause Leukemic Transformation

Edwin Chen, Lawrence J Breyfogle, Rebekka K. Schneider, MD, Luke Poveromo, BS, Ross L. Levine, MD, Benjamin L. Ebert, MD, PhD, Ann Mullally, MD
Journal: Blood
Blood (2013) 122 (21): 4095.
https://doi.org/10.1182/blood.V122.21.4095.4095
Published: 2013
Journal Articles

Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera

Ann Mullally, Claudia Bruedigam, Luke Poveromo, Florian H. Heidel, Amy Purdon, Therese Vu, Rebecca Austin, Dirk Heckl, Lawrence J. Breyfogle, Catherine Paine Kuhn, Demetrios Kalaitzidis, Scott A. Armstrong, David A. Williams, Geoff R. Hill, Benjamin L. Ebert, Steven W. Lane
Journal: Blood
Blood (2013) 121 (18): 3692–3702.
https://doi.org/10.1182/blood-2012-05-432989
Published: 2013
Includes: Supplemental data