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Larry H. Boise
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Journal Articles

Disrupting Ectopic Super-Enhancers to Treat Multiple Myeloma

Seth Welsh, Daniel Riggs, Erin Meermeier, Chang-Xin Shi, Victoria Garbitt, Meaghen E Sharik, Megan Du, Kennedi Todd, Zachary Hammond, Sochilt Brown, Caleb K Stein, Paola Neri, Nizar J. Bahlis, Benjamin G Barwick, Larry H. Boise, W. Michael Kuehl, Marta Chesi, P. Leif Bergsagel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1593.
https://doi.org/10.1182/blood-2021-147551
Published: 2021
Journal Articles

Daratumumab with Pomalidomide and Dexamethasone at First Relapse in Relapsed and/or Refractory Multiple Myeloma (RRMM) Patients

Nisha Joseph, Kathryn T. Maples, Kevin Hall, Vikas A Gupta, Larry H. Boise, Leonard T. Heffner, Madhav V Dhodapkar, Craig C. Hofmeister, Jonathan L. Kaufman, Sagar Lonial, Ajay K. Nooka
Journal: Blood
Blood (2021) 138 (Supplement 1): 1616.
https://doi.org/10.1182/blood-2021-151161
Published: 2021
Journal Articles

Elongator Complex Regulates MCL1 Dependency Via IRE1-XBP1 Axis of the ER Stress Response Pathway in Multiple Myeloma

Neeraj K Aryal, Anjana Sundarrajan, Scott Boiko, David Jenkins, Huayang Liu, Miika Ahdesmaki, Aurelie Bornot, Andrew Jarnuczak, Eric Miele, Ultan McDermott, Stephen Fawell, Lisa Drew, Larry H. Boise, Justin Cidado
Journal: Blood
Blood (2021) 138 (Supplement 1): 2275.
https://doi.org/10.1182/blood-2021-151194
Published: 2021
Journal Articles

Functional Genomic Characterization of Endoplasmic Reticulum-Associated Dependencies in Multiple Myeloma - Biologic and Therapeutic Implications

Ryosuke Shirasaki, MD PhD, Ricardo De Matos Simoes, PhD, Shizuka Yamano, Sondra L. Downey-Kopyscinski, PhD, Brian Glassner, PhD, Huihui Tang, PhD, Vikas Gupta, MD PhD, Aviad Tsherniak, PhD, Francisca Vazquez, PhD, Jonathan D. Licht, MD, Larry H. Boise, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-143117
Published: 2020
Journal Articles

POU2AF1 As a Master Regulator of Oncogenic Transcription Factor Networks in Myeloma

Ricardo De Matos Simoes, PhD, Ryosuke Shirasaki, MD, Huihui Tang, PhD, Shizuka Yamano, Benjamin G Barwick, PhD, Sara Gandolfi, MD, Eugen Dhimolea, PhD, Sondra L. Downey-Kopyscinski, PhD, Olga Dashevsky, PhD, Brian Glassner, PhD, Michal Sheffer, PhD, Dhvanir Kansara, Megan Bariteau, BSc, Jeffrey Sorrell, BA, Vikas Gupta, MD PhD, Aedin Culhane, PhD, Aviad Tsherniak, PhD, Francisca Vazquez, PhD, Larry H. Boise, PhD, Jonathan D. Licht, MD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-142580
Published: 2020
Journal Articles

Interactions with a "Humanized" Mesenchymal Bone Marrow Stromal Niche In Vivo Modify the Patterns of Essential Genes for Myeloma Cells: Therapeutic Implications

Ryosuke Shirasaki, MD PhD, Sondra L. Downey-Kopyscinski, PhD, Ricardo De Matos Simoes, PhD, Olga Dashevsky, Sara Gandolfi, MD, Megan Bariteau, BSc, Aviad Tsherniak, PhD, Francisca Vazquez, PhD, Maria Themeli, MD PhD, Jonathan D. Licht, MD, Larry H. Boise, PhD, Richard W.J. Groen, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40.
https://doi.org/10.1182/blood-2020-143151
Published: 2020
Journal Articles

Chromatin Accessibility Identifies Regulatory Elements Predictive of Oncogene Expression in Multiple Myeloma

Benjamin G Barwick, PhD, Vikas A. Gupta, MD PhD, Shannon M Matulis, PhD, Jonathan C Patton, B.S., Doris R Powell, MA, Yanyan Gu, MD PhD, David L. Jaye, MD, Karen N Conneely, PhD, Yin C Lin, PhD, Craig C Hofmeister, MDMPH, Ajay Nooka, MDMPH, Jonathan J Keats, PhD, Sagar Lonial, MD FACP, Paula M Vertino, PhD, Larry H. Boise, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-140717
Published: 2020
Journal Articles

Use of Olfactory Receptor Genes As Controls for Genome-Scale CRISPR Functional Genomic Studies to Define Treatment Resistance Mechanisms

Olga Dashevsky, PhD, Ricardo De Matos Simoes, PhD, Ryosuke Shirasaki, MD, Michal Sheffer, PhD, Eugen Dhimolea, PhD, Sara Gandolfi, MD, Huihui Tang, PhD, Sondra L. Downey-Kopyscinski, PhD, Megan Bariteau, B.Sc., Jeffrey Sorrell, BA, Brian Glassner, PhD, John Doench, PhD, Larry H. Boise, PhD, Jonathan D. Licht, MD, Aedin Culhane, PhD, William C. Hahn, MD PhD, Francisca Vazquez, PhD, Aviad Tsherniak, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36.
https://doi.org/10.1182/blood-2020-142651
Published: 2020
Journal Articles

Role of clonoSEQ ® , a Next-Generation Sequencing (NGS) Assay and PET/CT As a Measure of Minimal Residual Disease Negativity Among Patients with Multiple Myeloma

Ajay Nooka, MDMPH, Kyle Bradley, MD MS, Nisha Joseph, MD, Craig C Hofmeister, MDMPH, Madhav V. Dhodapkar, MD, Larry H. Boise, PhD, Sagar Lonial, MD FACP, Shiyong Li, MD PhD, Jonathan L. Kaufman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50–51.
https://doi.org/10.1182/blood-2020-143093
Published: 2020
Journal Articles

Clinical Efficacy of Daratumumab, Pomalidomide and Dexamethasone in Relapsed, Refractory Myeloma Patients: Utility of Retreatment with Daratumumab Among Refractory Patients

Ajay K Nooka, MD MPH, Nisha Joseph, MD, Larry H Boise, PhD, Charise Gleason, MSN, ANP-BC, AOCNP, Jonathan L. Kaufman, MD, Sagar Lonial, MD FACP
Journal: Blood
Blood (2016) 128 (22): 492.
https://doi.org/10.1182/blood.V128.22.492.492
Published: 2016
Journal Articles

IKZF1 Regulates BRD4 Retention and Recruitement at Enhancer in Myeloma Cells: Role of BRD4 in IMiDs Resistance

Paola Neri, MD PhD, Ines Tagoug, PhD, Ranjan Maity, PhD, Jacquelyn Babich, Lindsay Lockwood, Jonathan J Keats, PhD, Larry H Boise, PhD, Leif Bergsagel, MD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2016) 128 (22): 358.
https://doi.org/10.1182/blood.V128.22.358.358
Published: 2016