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Meaghen E Sharik
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Journal Articles

IMiDs Synergize with EP300 Inhibition to Disrupt the Ikzf/MYC/IRF4 Axis in Multiple Myeloma

Seth J Welsh, Benjamin G Barwick, Erin Meermeier, Daniel Riggs, Chang-Xin Shi, Yuan Xiao Zhu, Meaghen E Sharik, Megan T Du, Victoria Marie Garbitt, Caleb K Stein, Joachim L Petit, Nathalie Meurice, Rodrigo Fonseca, Kennedi Todd, Sochilt Brown, Yuliza Tafoya Alvarado, Zachary Hammond, Nicklus Cuc, Courtney Wittenberg, Camille Herzog, Lawrence H. Boise, Nizar J. Bahlis, Paola Neri, W. Michael Kuehl, Marta Chesi, P. Leif Bergsagel
Journal: Blood
Blood (2022) 140 (Supplement 1): 12997.
https://doi.org/10.1182/blood-2022-169920
Published: 2022
Journal Articles

Vκ*MYC Mouse Model Recapitulates Key Genomic Defining Events in Multiple Myeloma

Francesco Maura, David Coffey, Esteban Braggio, Caleb K Stein, Meaghen E Sharik, Megan T Du, Bachisio Ziccheddu, Gareth J. Morgan, Ola Landgren, P. Leif Bergsagel, Marta Chesi
Journal: Blood
Blood (2022) 140 (Supplement 1): 1540–1541.
https://doi.org/10.1182/blood-2022-166614
Published: 2022
Journal Articles

Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined T Cell Engager and Cytotoxic Therapy in a Multiple Myeloma Preclinical Model

Erin Meermeier, Caleb K Stein, Meaghen E Sharik, Yuan Xiao Zhu, Megan T Du, Seth J Welsh, Chang-Xin Shi, Matthew L Wheeler, P. Leif Bergsagel, Marta Chesi
Journal: Blood
Blood (2022) 140 (Supplement 1): 7056–7057.
https://doi.org/10.1182/blood-2022-167668
Published: 2022
Journal Articles

Disrupting Ectopic Super-Enhancers to Treat Multiple Myeloma

Seth Welsh, Daniel Riggs, Erin Meermeier, Chang-Xin Shi, Victoria Garbitt, Meaghen E Sharik, Megan Du, Kennedi Todd, Zachary Hammond, Sochilt Brown, Caleb K Stein, Paola Neri, Nizar J. Bahlis, Benjamin G Barwick, Larry H. Boise, W. Michael Kuehl, Marta Chesi, P. Leif Bergsagel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1593.
https://doi.org/10.1182/blood-2021-147551
Published: 2021
Journal Articles

A Single-Cell Transcriptional Analysis of Tumour Cells and the Immune Microenvironment during Disease Evolution in a Transgenic Mouse Model of Myeloma

Danielle C Croucher, MSc, Marta Chesi, PhD, Zhihua Li, Victoria Marie Garbitt, BS, Meaghen E Sharik, BS, Daniel Waller, PhD, Michael Sebag, MD PhD, P. Leif Bergsagel, MD, Trevor J. Pugh, PhD, Suzanne Trudel, MD FRCP(C)
Journal: Blood
Blood (2018) 132 (Supplement 1): 56.
https://doi.org/10.1182/blood-2018-99-118691
Published: 2018
Journal Articles

PIKfyve Inhibitors for the Treatment of Multiple Myeloma

Cecilia Bonolo De Campos, PhD, Yuan Xiao Zhu, PhD, Chang-Xin Shi, PhD, Laura Ann Bruins, BS, Joachim L Petit, PhD, Alysia N Polito, BS, Meaghen E Sharik, BS, Caleb K Stein, MS, Gregory J Ahmann, BS, Ilsel D Lopez Armenta, BS, Nikolai Sepetov, PhD, Sergei Romanov, PhD, P. Leif Bergsagel, MD, Marta Chesi, PhD, Nathalie Meurice, PhD, A. Keith Stewart, MBChB, MBA
Journal: Blood
Blood (2017) 130 (Supplement 1): 4423.
https://doi.org/10.1182/blood.V130.Suppl_1.4423.4423
Published: 2017
Journal Articles

Translational Research of PT-112, a Clinical Agent in Advanced Phase I Development: Evident Bone Tropism, Synergy In Vitro with Bortezomib and Lenalidomide , and Potent Efficacy in the Vk*MYC Mouse Model of Multiple Myeloma

Tyler D Ames, PhD, Meaghen E Sharik, BS, Gulam M Rather, PhD, Guillaume Hochart, MPhil, David Bonnel, PhD, Stefan Linehan, Jonathan Stauber, PhD, Richard A Wing, PhD, Jose J Jimeno, MD, Daniel Medina, PhD, Joseph R Bertino, MD, Marta Chesi, PhD, P. Leif Bergsagel, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1797.
https://doi.org/10.1182/blood.V130.Suppl_1.1797.1797
Published: 2017