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Kristine Crews
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Tolerability of 6-Mercaptopurine (6MP) in Patients with Thiopurine Methyltransferase ( TPMT ) Heterozygosity in the Context of Multi-Agent Therapy for Acute Lymphoblastic Leukemia (ALL)

Chengcheng Liu, Deqing Pei, MS, Cheng Cheng, PhD, Jun J. Yang, PhD, Kristine Crews, PharmD, Wenjian Yang, PhD, Seth E. Karol, MD, Sima Jeha, MD, John T. Sandlund, MD, Raul C Ribeiro, MD, Jeffrey E Rubnitz, MD PhD, Monika L. Metzger, MD MS, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD
Journal: Blood
Blood (2014) 124 (21): 3722.
https://doi.org/10.1182/blood.V124.21.3722.3722
Published: 2014
Journal Articles

Genome-Wide Association Analyses Identify Susceptibility Loci For Vincristine-Induced Peripheral Neuropathy In Children With Acute Lymphoblastic Leukemia

Barthelemy Diouf, PhD, PharmD, Kristine Crews, PharmD, Glen Lew, MD, Deqing Pei, MS, Cheng Cheng, PhD, Ju Bao, PhD, Jie Zheng, PhD, Wenjian Yang, PhD, Yiping Fan, Steven W. Paugh, PhD, Joseph Robert McCorkle, PhD, Xiaomin Lu, Naomi J. Winick, MD, William L. Carroll, MD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Meenakshi Devidas, PhD, Ching-Hon Pui, MD, Mary V. Relling, PharmD, William E. Evans, PharmD
Journal: Blood
Blood (2013) 122 (21): 618.
https://doi.org/10.1182/blood.V122.21.618.618
Published: 2013
Journal Articles

Cytarabine-Induced Gene Expression Signatures in AML Patients and Its Association with Clinical Outcome.

Jatinder K. Lamba, PhD, Stanley Pounds, PhD, Xueyuan Cao, PhD, Kristine Crews, PharmD, Dario Campana, MD., PhD, James R. Downing, MD, Raul Ribeiro, MD, Jeffrey Rubnitz, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2470.
https://doi.org/10.1182/blood.V120.21.2470.2470
Published: 2012
Journal Articles

PDE4B Modulates Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia

Jun J. Yang, PhD, Shuyu E, PhD, Shuhong Shen, MD, PhD, Deepa Bhojwani, MD, Huining Kang, PhD, Yani Ma, PhD, Jing Chen, MD, PhD, JingYan Tang, MD, Nita L. Seibel, MD, Heng Xu, PhD, Jin Cheng, Laura B. Ramsey, PhD, Kristine Crews, PharmD, W. Paul Bowman, MD, Michael J. Borowitz, MD, PhD, William L. Carroll, MD, Cheryl L. Willman, MD, Sima Jeha, MD, Ching-Hon Pui, MD, Stephen P. Hunger, MD, Mary V. Relling, PharmD, William E. Evans, PharmD
Journal: Blood
Blood (2012) 120 (21): 530.
https://doi.org/10.1182/blood.V120.21.530.530
Published: 2012
Journal Articles

Clinical Utility and Implications of Asparaginase Antibodies in Acute Lymphoblastic Leukemia

Chengcheng Liu, Jitesh D. Kawedia, PhD, RPh, Cheng Cheng, PhD, Deqing Pei, MS, Christian A Fernandez, PhD, Xiangjun Cai, PhD, Kristine Crews, Sue Kaste, DO, John C Panetta, PhD, W. Paul Bowman, MD, Sima Jeha, MD, John Sandlund, MD, William E. Evans, PharmD, Ching-Hon Pui, MD, Mary V. Relling, PharmD
Journal: Blood
Blood (2011) 118 (21): 1481.
https://doi.org/10.1182/blood.V118.21.1481.1481
Published: 2011
Journal Articles

Pathway Based Pharmacogenomics of Cytarabine In Pediatric Acute Myeloid Leukemia

Jatinder Lamba, PhD, Amit Mitra, Kristine Crews, Pounds Stanley, PhD, Xueyuan Cao, PhD, Varsha Gandhi, PhD, William Plunkett, PhD, Jeffrey Rubnitz, MD, PhD, Raul Ribeiro
Journal: Blood
Blood (2010) 116 (21): 294.
https://doi.org/10.1182/blood.V116.21.294.294
Published: 2010
Journal Articles

5'Nucleotidase (NT5C2) Genotype Influences Leukemic Blast Concentration of Ara-CTP in Pediatric Patients with Acute Myeloid Leukemia.

Jatinder K. Lamba, Amit Mitra, Kristine Crews, Stanley Pounds, Xueyuan Cao, Varsha Gandhi, William Plunkett, Jeffrey Rubnitz, Raul C Ribeiro
Journal: Blood
Blood (2009) 114 (22): 593.
https://doi.org/10.1182/blood.V114.22.593.593
Published: 2009
Journal Articles

Gene Expression Patterns Associated with Cytarabine Pharmacology and Outcome in Pediatric Acute Myeloid Leukemia.

Jatinder K. Lamba, Kristine Crews, Stanley Pounds, Xueyuan Cao, Varsha Gandhi, William Plunkett, Sharyn D. Baker, Ching-Hon Pui, Dario Campana, James R. Downing, MD, Jeffrey Rubnitz, Raul C Ribeiro
Journal: Blood
Blood (2009) 114 (22): 114.
https://doi.org/10.1182/blood.V114.22.114.114
Published: 2009
Journal Articles

Gene Expression Profiling of Acute Myeloid Leukemia Shows Therapeutically Meaningful Patterns of Association with Ara-CTP Pharmacokinetics and Pharmacodynamics

Jatinder K. Lamba, Kristine Crews, Stanley Pounds, Xueyuan Cao, Sharyn D. Baker, Varsha Gandhi, William Plunkett, James R. Downing, Jeffrey Rubnitz, Raul C. Ribeiro
Journal: Blood
Blood (2008) 112 (11): 215.
https://doi.org/10.1182/blood.V112.11.215.215
Published: 2008
Journal Articles

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

Jun J. Yang, Deepa Bhojwani, Wenjian Yang, Xiangjun Cai, Gabriele Stocco, Kristine Crews, Jinhua Wang, Debra Morrison, Meenakshi Devidas, Stephen P. Hunger, Cheryl L. Willman, Elizabeth A. Raetz, Ching-hon Pui, William E. Evans, Mary V. Relling, William L. Carroll
Journal: Blood
Blood (2008) 112 (10): 4178–4183.
https://doi.org/10.1182/blood-2008-06-165027
Published: 2008
Includes: Supplemental data
Journal Articles

Deoxycytidine Kinase Genotype Influences Leukemia Cell Concentration of Cytarabine 5′-Triphosphate in Pediatric AML Patients.

Jatinder Lamba, PhD, Kristine Crews, Pharm. D, Stanley Pounds, Ph.D., Erin Schuetz, Ph.D., Varsha Gandhi, Ph.D., William Plunkett, Ph.D., Jeffrey Rubnitz, M.D., Ph.D., Raul Ribeiro, M.D
Journal: Blood
Blood (2007) 110 (11): 225.
https://doi.org/10.1182/blood.V110.11.225.225
Published: 2007
Journal Articles

Inosine-Triphosphate-Pyrophosphatase Genotype Is a Determinant of Severe Fever with Neutropenia Following Treatment of Acute Lymphoblastic Leukemia with Combination Chemotherapy That Includes Mercaptopurine Adjusted for Thiopurine-S-Methyltransferase Genotype.

Gabriele Stocco, PhD, Meyling Cheok, PhD, Wenjian Yang, PhD, Thierry Dervieux, PharmD/PhD, Kristine Crews, PharmD, Deqing Pei, Cheng Cheng, PhD, Ching-Hon Pui, MD, Mary V. Relling, PharmD, William E. Evans, PharmD
Journal: Blood
Blood (2007) 110 (11): 2827.
https://doi.org/10.1182/blood.V110.11.2827.2827
Published: 2007