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Kieran O’Neill
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Journal Articles

Chromatin Architecture Protein CTCF Plays a Role in Determining 5-Azacytidine Response of Leukemic Cells By Potentially Regulating Hoxb Genes

Aparna Gopal, Derek Tam, Ryan J. Stubbins, Kieran O'Neill, Marion Shadbolt, Deborah Deng, Rena Buckstein, Aly Karsan
Journal: Blood
Blood (2022) 140 (Supplement 1): 5850–5851.
https://doi.org/10.1182/blood-2022-170674
Published: 2022
Journal Articles

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Hanyang Lin, Katharina Rothe, Min Chen, Andrew Wu, Artem Babaian, Ryan Yen, Jonathan Zeng, Jens Ruschmann, Oleh I. Petriv, Kieran O'Neill, Tobias Maetzig, David J. H. F. Knapp, Naoto Nakamichi, Ryan Brinkman, Inanc Birol, Donna L. Forrest, Carl Hansen, R. Keith Humphries, Connie J. Eaves, Xiaoyan Jiang
Journal: Blood
Blood (2020) 136 (5): 596–609.
https://doi.org/10.1182/blood.2019003636
Published: 2020
Includes: Supplemental data
Journal Articles

Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice

Jennifer M. Grants, Joanna Wegrzyn, Tony Hui, Kieran O’Neill, Marion Shadbolt, David J. H. F. Knapp, Jeremy Parker, Yu Deng, Aparna Gopal, T. Roderick Docking, Megan Fuller, Jenny Li, Mark Boldin, Connie J. Eaves, Martin Hirst, Aly Karsan
Journal: Blood
Blood (2020) 135 (25): 2235–2251.
https://doi.org/10.1182/blood.2019003105
Published: 2020
Includes: Supplemental data
Journal Articles

Global Transcriptome Profiling Identifies a Key Mir-185-PAK6 Axis That Promotes Survival of Leukemic Stem Cells and Drug-Insensitive Blasts in BCR-ABL + Human Leukemia

Andrew Wu, BSc, Lin Hanyang, PhD, Katharina Rothe, PhD, Min Chen, MD PhD, Jens Ruschmann, PhD, Oleh Petriv, PhD, Kieran O'Neill, PhD, Tobias Maetzig, MD, David Knapp, PhD, Naoto Nakamichi, MD PhD, Ryan Brinkman, PhD, Inanc Birol, PhD, Donna L Forrest, MD, Carl Hansen, PhD, R. Keith Humphries, MD PhD, Connie J. Eaves, PhD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 931.
https://doi.org/10.1182/blood-2018-99-113559
Published: 2018
Journal Articles

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

Jennifer Grants, PhD, Joanna Wegrzyn, PhD, David Knapp, PhD, Tony Hui, Kieran O'Neill, PhD, Jeremy Parker, PhD, Deborah Deng, Mark Boldin, PhD, Martin Hirst, PhD, Connie J. Eaves, PhD, Aly Karsan, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 714.
https://doi.org/10.1182/blood.V130.Suppl_1.714.714
Published: 2017
Journal Articles

Identification and Characterization of New Microrna Biomarkers and Target Genes in Drug-Insensitive CD34+ CML Stem/Progenitor Cells Using Global Comparative RNA-Seq Analyses

Hanyang Lin, BSc, MSc, Jonathan Zeng, Katharina Rothe, BSc, MSc, Jens Ruschmann, PhD, Oleh Petriv, PhD, Kieran O'Neill, PhD, Tobias Maetzig, PhD, David Knapp, BSc, Ryan R. Brinkman, PhD, Inanc Birol, PhD, Donna L. Forrest, MD, Carl Hansen, PhD, Connie J. Eaves, PhD, R. Keith Humphries, MD PhD, Xiaoyan Jiang, MDPhD
Journal: Blood
Blood (2015) 126 (23): 1567.
https://doi.org/10.1182/blood.V126.23.1567.1567
Published: 2015
Journal Articles

Identification of New microRNA Biomarkers and Candidate Target Genes in Primitive CML Cells Using Global Comparative RNA analyses

Hanyang Lin, Katharina Rothe, Jens Ruschmann, Oleh Petriv, Kieran O'Neill, David J.H.F. Knapp, Ryan R. Brinkman, Inanc Birol, Donna L. Forrest, MD, Carl Hansen, Connie J Eaves, R. Keith Humphries, MD PhD, Xiaoyan Jiang
Journal: Blood
Blood (2014) 124 (21): 3133.
https://doi.org/10.1182/blood.V124.21.3133.3133
Published: 2014