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Journal Articles

Lentiviral vectors engineered for direct In Vivo delivery to resting T cells

Free
Gopal Naik Nenavath, Md Sharif Hasan, Nainika Ravichandran, Tatenda Kadungure, Karina Krotova, Collin Gwilt, Ajay Kumar, Nandakumar Packiriswamy, Pragati Jain, Chia-Hsuan Chin, Kyle Gromer, Rianna Vandergaast, Colby Feser, Miguel A Muñoz Alía, Patrycja Lech, Timothy Carey, Christian Kinney, Hamid Salimi, Kah-Whye Peng, Stephen Russell
Journal: Blood
Blood (2025) 146 (Supplement 1): 5902.
https://doi.org/10.1182/blood-2025-5902
Published: 2025
Journal Articles

Intravenously administered LV-169 delivers a functional BCMA-CAR transgene to niche-resident T cells and leads to elimination of disseminated myeloma in MHC-deficient NSG mice

Free
Stephen Russell, Gopal Naik Nenavath, Nandakumar Packiriswamy, Timothy Carey, Md Yeashin Gazi, Aaron Hawkes, Collin Gwilt, Chia-Hsuan Chin, Christian Kinney, Hamid Salimi, Thipparat Suwanmanee, Darren Phung, Karina Krotova, Rianna Vandergaast, Kartika Venugopal, Edward Briercheck, Eric Smith, Yi Lin, Kah-Whye Peng
Journal: Blood
Blood (2025) 146 (Supplement 1): 5896.
https://doi.org/10.1182/blood-2025-5896
Published: 2025
Journal Articles

In Vivo Generation of Functional CD19 CAR-T Cells Using a Serum-Stable CD3-Targeted Lentiviral Vector

Free
Karina Krotova, Gopal Naik Nenavath, Nandakumar Packiriswamy, Rianna Vandergaast, Melissa Moy, Christopher Ziegler, Miguel A Muñoz Alía, Kah-Whye Peng, Stephen Russell
Journal: Blood
Blood (2023) 142 (Supplement 1): 767.
https://doi.org/10.1182/blood-2023-186992
Published: 2023
Journal Articles

Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon, in Patients with Relapsed or Refractory Multiple Myeloma, Lymphomas, or Histiocytic/Dendritic Cell Neoplasms

Free
N. Nora Bennani, Joselle Cook, Susan M. Geyer, Brenda F Ginos, Lianwen Zhang, Javier Munoz, Stephen Broski, Stephen Russell, Kah-Whye Peng, Martha Lacy
Journal: Blood
Blood (2023) 142 (Supplement 1): 5004.
https://doi.org/10.1182/blood-2023-190664
Published: 2023
Journal Articles

An Analysis of Virus Amplification and Antitumor Responses in T-Cell Lymphoma Patients Treated with Voyager-V1 ( VSV-IFNβ-NIS)

Free
Joselle Cook, Kah-Whye Peng, Thomas E. Witzig, Stephen Broski, Jose C. Villasboas, Jonas Paludo, Mrinal M. Patnaik, S. Vincent Rajkumar, Angela Dispenzieri, Nelson Leung, Francis K. Buadi, N. Nora Bennani, Stephen M. Ansell, Lianwen Zhang, Nandakumar Pakiriswamy, Baskar Balakrishnan, Bethany Brunton, Marissa Giers, Brenda F Ginos, Amylou C. Dueck, Susan M. Geyer, Morie A. Gertz, Rahma M Warsame, Ronald Go, Suzanne R. Hayman, David Dingli, Shaji Kumar, P. Leif Bergsagel, Wilson I Gonsalves, Taxiarchis Kourelis, Eli Muchtar, Prashant Kapoor, Robert A. Kyle, Yi Lin, Mustaqeem A. Siddiqui, Amie Fonder, Miriam A. Hobbs, Yi L. Hwa, Stephen J. Russell, Martha Q. Lacy
Journal: Blood
Blood (2021) 138 (Supplement 1): 1333.
https://doi.org/10.1182/blood-2021-153184
Published: 2021
Journal Articles

Vesicular Stomatitis Virus (VSV) Engineered to Express CD19 Stimulates Anti-CD19 Chimeric Antigen Receptor Modified T Cells and Promotes Their Anti-Tumor Effects

Free
Reona Sakemura, MDPhD, Elizabeth C. Eckert, PhD, Sydney B. Crotts, Linh Pham, Elizabeth L. Siegler, PhD, Michelle J. Cox, Erin E. Tapper, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Ismail Can, Evandro D. Bezerra, MD, Lionel Kankeu Fonkoua, MD, Paulina Horvei, MD, Michael W. Ruff, MD, Susan L. Slager, PhD, Sameer A. Parikh, MD, Neil E. Kay, MD, Kah-Whye Peng, PhD, Stephen J. Russell, MD PhD, Saad S. Kenderian, MB, ChB
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-139647
Published: 2020
Journal Articles

Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon Beta, in Patients with Relapsed or Refractory Multiple Myeloma (MM), Acute Myeloid Leukemia (AML), and T-Cell Neoplasms (TCL)

Free
Joselle Cook, MBBS, Kah-Whye Peng, PhD, Brenda F Ginos, B.A., Amylou C. Dueck, PhD, Marissa Giers, BSN, RN, Nandakumar Packiriswamy, PhD DVM, Beth Brunton, PhD, Mrinal M. Patnaik, MDMBBS, Thomas E. Witzig, MD, Francis K. Buadi, MB, CHB, Angela Dispenzieri, MD, Morie A Gertz, MD, Ronald S. Go, MD, Suzanne R. Hayman, MD, John A. Lust, MD PhD, David Dingli, MD PhD, S. Vincent Rajkumar, MD, Nelson Leung, MD, Rahma M Warsame, MD, Wilson I Gonsalves, MD, Taxiarchis Kourelis, MD, Eli Muchtar, MD, P. Leif Bergsagel, MD, Stephen Broski, MD, Prashant Kapoor, MD, Robert A. Kyle, MD, Mustaqeem A. Siddiqui, MDMBA, Amie Fonder, PA-C, MS, Miriam A. Hobbs, APRN, CNP, DNP, Yi L. Hwa, NP, Yi Lin, MD PhD, Shaji K. Kumar, MD, Stephen J. Russell, MD PhD, Martha Q. Lacy, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-140853
Published: 2020
Journal Articles

Development of a Sensitive and Efficient Reporter Platform for the Detection of Chimeric Antigen Receptor T Cell Expansion, Trafficking, and Toxicity

Free
Reona Sakemura, MD PhD, Lukkana Suksanpaisan, PhD, Roman H Khadka, Alysha N Newsom, Michael J. Hansen, Michelle J. Cox, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Erin E. Tapper, Paulina Roman Moreno, MD, Michael W. Ruff, MD, Sameer A. Parikh, MD, Neil E. Kay, MD, Kah-Whye Peng, PhD, Stephen J Russell, MD PhD, Saad S. Kenderian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 53.
https://doi.org/10.1182/blood-2019-123476
Published: 2019
Journal Articles

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

Free
Xiaosheng Wu, Mary Stenson, Jithma Abeykoon, Kevin Nowakowski, Lianwen Zhang, Joshua Lawson, Linda Wellik, Ying Li, Jordan Krull, Kerstin Wenzl, Anne J. Novak, Stephen M. Ansell, Gail A. Bishop, Daniel D. Billadeau, Kah Whye Peng, Francis Giles, Daniel M. Schmitt, Thomas E. Witzig
Journal: Blood
Blood (2019) 134 (4): 363–373.
https://doi.org/10.1182/blood.2018874560
Published: 2019
Includes: Supplemental data
Journal Articles

Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon, in Patients with Relapsed or Refractory Multiple Myeloma (MM), Acute Myeloid Leukemia (AML), and T-Cell Neoplasms (TCL)

Free
Martha Q. Lacy, MD, Kah-Whye Peng, PhD, Stephen J. Russell, MD PhD, Amylou C. Dueck, PhD, Mrinal M. Patnaik, MD MBBS, Thomas E. Witzig, MD, Brenda F Ginos, Francis K. Buadi, MB, CHB, Angela Dispenzieri, MD, Morie A. Gertz, MD, Ronald S. Go, MD, Suzanne R. Hayman, MD, John A. Lust, MD PhD, David Dingli, MD PhD, S. Vincent Rajkumar, MD, Nelson Leung, MD, Rahma Warsame, MD, Wilson I Gonsalves, MD, Taxiarchis Kourelis, MD, Eli Muchtar, MD, Stephen Broski, MD, Robert C Murphy, MD PhD, Prashant Kapoor, MD, Robert A. Kyle, MD, Steven Zeldenrust, MD, Aref Al-Kali, MD, Mark R. Litzow, MD, Shruthi Naik, PhD, Mark J Federspiel, PhD, Shaji K. Kumar, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3268.
https://doi.org/10.1182/blood-2018-99-119444
Published: 2018
Journal Articles

T Cell Responses to Tumor Associated Antigens in Multiple Myeloma Patients Treated with MV-NIS, an Oncolytic Measles Virus

Free
Nandakumar Packiriswamy, PhD DVM, Deepak Upreti, PhD, Yumei Zhou, PhD, Angela Dispenzieri, MD, Kah-Whye Peng, PhD, Stephen J. Russell, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3793.
https://doi.org/10.1182/blood.V130.Suppl_1.3793.3793
Published: 2017
Journal Articles

Ruxolitinib Rescues Mice from Lethal Interferon Beta Toxicity and TLS

Free
Kah-Whye Peng, PhD, Linh Pham, Lianwen Zhang, PhD, Rebecca Nace, Nathan Jenks, Michael Steele, Alysha Newsom, Ronald Marler, DVM, PhD, Martha Q Lacy, MD, Stephen J. Russell, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1807.
https://doi.org/10.1182/blood.V130.Suppl_1.1807.1807
Published: 2017
Journal Articles

Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia

Free
Weiwei Shen, Mrinal M. Patnaik, Autumn Ruiz, Stephen J. Russell, Kah-Whye Peng
Journal: Blood
Blood (2016) 127 (11): 1449–1458.
https://doi.org/10.1182/blood-2015-06-652503
Published: 2016
Includes: Supplemental data
Journal Articles

Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors

Free
Cecilia Frecha, Caroline Costa, Camille Lévy, Didier Nègre, Stephen J. Russell, Andrea Maisner, Gilles Salles, Kah-Whye Peng, Francois-Loïc Cosset, Els Verhoeyen
Journal: Blood
Blood (2009) 114 (15): 3173–3180.
https://doi.org/10.1182/blood-2009-05-220798
Published: 2009
Includes: Supplemental data
Journal Articles

Pre-Clinical Data and Preliminary Patient Results of Intravenous MV-NIS To Treat Relapsed, Refractory Multiple Myeloma.

Free
Angela Dispenzieri, Rae M. Myers, Caili Tong, Suzanne M. Greiner, Mary E. Harvey, Guy Griesmann, Joel Reid, Mark Federspiel, Matthew M. Ames, David Dingli, Martha Q. Lacy, Morie A. Gertz, Karen Schweikwart, Anthony Welch, Kah-Whye Peng, Stephen J. Russell
Journal: Blood
Blood (2007) 110 (11): 1181.
https://doi.org/10.1182/blood.V110.11.1181.1181
Published: 2007
Journal Articles

Tumor Associated Macrophages (TAM) in Skeletal Plasmacytomas of Patients with Multiple Myeloma.

Free
Stephen J. Russell, MD, PhD, Ahmet Dogan, MD, Hooi Tin Ong, PhD, Julie Vrana, PhD, Angela Dispenzieri, MD, Allan B. Dietz, PhD, Kah-Whye Peng, PhD
Journal: Blood
Blood (2007) 110 (11): 114.
https://doi.org/10.1182/blood.V110.11.114.114
Published: 2007
Journal Articles

Synergistic activity of the proteasome inhibitor PS-341 with non-myeloablative 153-Sm-EDTMP skeletally targeted radiotherapy in an orthotopic model of multiple myeloma

Free
Apollina Goel, Angela Dispenzieri, Susan M. Geyer, Suzanne Greiner, Kah-Whye Peng, Stephen J. Russell
Journal: Blood
Blood (2006) 107 (10): 4063–4070.
https://doi.org/10.1182/blood-2005-09-3870
Published: 2006
Journal Articles

Interaction of Measles Virus Vectors with Auger Electron Emitting Radioisotopes.

Free
David Dingli, MD, PhD, Kah-Whye Peng, PhD, Mary E. Harvey, Sompong Vongpunsawad, Elizabeth R. Bergert, Robert A. Kyle, MD, Roberto Cattaneo, PhD, John C. Morris, MD, Stephen J. Russell, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 5525.
https://doi.org/10.1182/blood.V106.11.5525.5525
Published: 2005
Journal Articles

Oncolytic Measles Virus Selectively Targets CD46 Overexpression on Myeloma Cells.

Free
Kah-Whye Peng, PhD, Michael M. Timm, David Dingli, MD, PhD, Angela Dispenzieri, MD, Morie Gertz, MD, Thomas E. Witzig, MD, Philip R. Greipp, MD, Stephen J. Russell, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 2392.
https://doi.org/10.1182/blood.V104.11.2392.2392
Published: 2004
Journal Articles

Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter

Free
David Dingli, Kah-Whye Peng, Mary E. Harvey, Philip R. Greipp, Michael K. O'Connor, Roberto Cattaneo, John C. Morris, Stephen J. Russell
Journal: Blood
Blood (2004) 103 (5): 1641–1646.
https://doi.org/10.1182/blood-2003-07-2233
Published: 2004