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Journal Articles

The Protective Role of Tubular Epithelial Cells Produced Fms-like Tyrosine Kinase Receptor 3 Ligand in Acute Kidney Injury

Na Li, Yao Guo, Zheqi Wen, Chuyu Xie, Mingcheng Huang, Jiang Shan, Yuming Zhao, Dengyang Zhang, Zhiguang Chang, Liuting Yu, Chi Kong Li, Zhihua Zheng, Zhizhuang Joe Zhao, Yun Chen

Blood (2023) 142 (Supplement 1): 2539.

https://doi.org/10.1182/blood-2023-174317

Published: 2023

Journal Articles

The Tubular Cells Produce Fms-like Tyrosine Kinase Receptor 3 Ligand to Recover Kidney Function after Acute Kidney Injury Disease

Na Li, Yao Guo, Zhihua Zheng, Yun Chen, Zhizhuang Joe Zhao

Blood (2022) 140 (Supplement 1): 8325.

https://doi.org/10.1182/blood-2022-155704

Published: 2022

Journal Articles

Niclosamide Inhibits the Growth of Acute Lymphoblastic Leukemia Cells By Increasing Intracellular ROS and Activation of p53-PUMA/NOXA

Junbin Huang, Jing Yang, Yun Chen, Zhizhuang Joe Zhao, Chun Chen

Blood (2022) 140 (Supplement 1): 5917.

https://doi.org/10.1182/blood-2022-168825

Published: 2022

Journal Articles

Aurora Kinase B/C Inhibitor GSK1070916 Specifically Targets Juvenile Myelomonocytic Leukemia Cells with SHP2(PTPN11) Mutation

Chunxiao He, Dengyang Zhang, Yao Guo, Yuming Zhao, Junbin Huang, Hongman Xue, Chun Chen, Yun Chen, Zhizhuang Joe Zhao

Blood (2022) 140 (Supplement 1): 3092.

https://doi.org/10.1182/blood-2022-168468

Published: 2022

Journal Articles

Novel Anti-CD117 Antibodies for Rapid and Efficient Hematopoietic Stem Cell Depletion and Safe Bone Marrow Conditioning

Giada Dal Collo, Antoinette van Hoven-Beijen, Yu He, Yvonne M Muller, Yuandong Wang, Joe Zhao, Peter D Katsikis, Stefan J Erkeland

Blood (2022) 140 (Supplement 1): 4496–4497.

https://doi.org/10.1182/blood-2022-158149

Published: 2022

Journal Articles

HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression

Blood (2022) 139 (18): 2797–2815.

https://doi.org/10.1182/blood.2021013925

Published: 2022

Includes: Supplemental data

Journal Articles

Establishment of Stable Cell Lines Representing Juvenile Myelomonocytic Leukemia with SHP2 Mutations

Yuming Zhao, Yao Guo, Chunxiao He, Dengyang Zhang, Han Zhong Pei, Ming Yang, Zhiguang Chang, Liuting Yu, Junbin Huang, Hongman Xue, Chun Chen, Zhizhuang Joe Zhao, Yun Chen

Blood (2021) 138 (Supplement 1): 4353.

https://doi.org/10.1182/blood-2021-150007

Published: 2021

Journal Articles

Small Molecule Kinase Inhibitor Sunitinib Specifically Targets Juvenile Myelomonocytic Leukemia Cells with SHP2(PTPN11) Mutation

Chunxiao He, Yuming Zhao, Junbin Huang, Yao Guo, Hongman Xue, Chun Chen, Yun Chen, Zhizhuang Joe Zhao

Blood (2021) 138 (Supplement 1): 3353.

https://doi.org/10.1182/blood-2021-149324

Published: 2021

Journal Articles

FLT3 Inhibitors Induce p53 Instability Due to Increased Interaction between p53 and MDM2 By Inhibiting STAT5 Phosphorylation in Acute Myeloid Leukemia

Han Zhong Pei, Xiaomei Zhuang, Ming Yang, Yao Guo, Zhiguang Chang, Dengyang Zhang, Yuming Zhao, Liuting Yu, Bo Lu, Xiaojun Xu, Yun Chen, Zhizhuang Joe Zhao

Blood (2021) 138 (Supplement 1): 3333.

https://doi.org/10.1182/blood-2021-149406

Published: 2021

Journal Articles

HMGA1 Chromatin Regulators Drive Progression in Myeloproliferative Neoplasms through Epigenetic Rewiring to Induce Networks Involved in GATA2 and Proliferation

Liping Li, Jung-Hyun Kim, Wenyan Lu, Leslie Cope, Donna M Williams, Joseph Kim, Raajit Rampal, Richard Koche, Lingling Xian, Li Luo, Marija Vasiljevic, Daniel R Matson, Zhizhuang Joe Zhao, Ophelia Rogers, Matthew C. Stubbs, Karen Reddy, Jerry L. Spivak, Alison R. Moliterno, Linda Resar

Blood (2021) 138 (Supplement 1): 625.

https://doi.org/10.1182/blood-2021-144712

Published: 2021

Journal Articles

FLT3 Inhibitors Induce Instability of p53 By Mir-181 Mediated Downregulation of Deubiquitinase YOD1 in Acute Myeloid Leukemia

Han Zhong Pei, Yao Guo, PhD, Bo Lu, MD, Zhiguang Chang, PhD, Dengyang Zhang, PhD, Liuting Yu, Yuming Zhao, Suk-Hwan Baek, PhD, Yun Chen, PhD, Zhizhuang Joe Zhao, PhD

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-139002

Published: 2020

Journal Articles

FLT3 Ligand-DM1 Conjugate Selectively Targets Acute Myeloid Leukemia Cells with FLT3 Expression

Dengyang Zhang, PhD, Yao Guo, PhD, Yuming Zhao, MD, Liuting Yu, Zhiguang Chang, PhD, Han Zhong Pei, Junbin Huang, MDPhD, Chun Chen, MDPhD, Hongman Xue, MDPhD, Yihang Pan, MD, Ningning Li, PhD, Chengming Zhu, PhD, Zhizhuang Joe Zhao, PhD, Jian Yu, PhD, Yun Chen, PhD

Blood (2020) 136 (Supplement 1): 30–31.

https://doi.org/10.1182/blood-2020-140200

Published: 2020

Journal Articles

Tumor Associated Macrophages Express High-Levels of FLT3 Ligand, Which Induces Activation of FLT3 Signaling That Promotes Survival of Neoplastic Cells in B-Cell Acute Lymphoblastic Leukemia

Yao Guo, PhD, Junbin Huang, MDPhD, Dengyang Zhang, PhD, Liqin Zhang, Yuming Zhao, Liuting Yu, Zhiguang Chang, PhD, Han Zhong Pei, Chun Chen, MDPhD, Hongman Xue, MDPhD, Xiaojun Xu, MDPhD, Zhizhuang Joe Zhao, PhD, Yun Chen, PhD

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-142093

Published: 2020

Journal Articles

Development of Liver-Specific Thrombopoietin Targeted Sirnas: Impact on Platelet Count, Megakaryocyte Mass, and Hematopoietic Progenitors in Normal and MPN Murine Models

Dhruv Desai, MSc, Anna Borodovsky, PhD, Wendell P Davis, DVM DACVP, Rohan Degaonkar, Kristina Yucius, Kellie D'Angelo, MLS(ASCP)CM, Paul Gedman, BS, Donna Marie Williams, PhD, Ophelia Rogers, Zhizhuang Joe Zhao, PhD, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 4329.

https://doi.org/10.1182/blood-2018-99-117142

Published: 2018

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Wenyan Lu, PhD, Briyana Chisholm, BS, Li Luo, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 102.

https://doi.org/10.1182/blood-2018-99-119549

Published: 2018

Journal Articles

Mechanism of Escape from LNK Negative Regulation: Constitutively Active JAK2V617F Retains Lysine63-Ubiquitin

Jeffrey Patterson-Fortin, MD PhD, Jerry L. Spivak, MD, Amy S. Duffield, MD PhD, Donna Marie Williams, PhD, Ophelia Rogers, Zhizhuang Joe Zhao, PhD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 2931.

https://doi.org/10.1182/blood.V130.Suppl_1.2931.2931

Published: 2017

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 489.

https://doi.org/10.1182/blood.V130.Suppl_1.489.489

Published: 2017

Journal Articles

Modulating Hedgehog Signaling Reduces MAPK, TGF-β, and Marrow Fibrosis in a Transgenic Mouse Model of JAK2V617F Associated Myeloproliferative Disease

Parvesh Chaudhry, PhD, Mohan Singh, PhD, Imran Siddiqi, MDPhD, Casey L. O'Connell, MD, Zhizhuang Joe Zhao, PhD, Akil Merchant, MD

Blood (2017) 130 (Supplement 1): 4216.

https://doi.org/10.1182/blood.V130.Suppl_1.4216.4216

Published: 2017

Journal Articles

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

Linda Resar, MD, Donna Marie Williams, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Lingling Xian, MD PhD, Jerry L. Spivak, MD, Alison R Moliterno, MD

Blood (2016) 128 (22): 1958.

https://doi.org/10.1182/blood.V128.22.1958.1958

Published: 2016

Journal Articles

Preclinical Efficacy of TGF-Beta Receptor I Kinase Inhibitor, Galunisertib, in Myelofibrosis

Lanzhu Yue, PhD, Matthias Bartenstein, Wanke Zhao, Wan-Ting Ho, Ling Zhang, MD, Franck Rapaport, PhD, Ross L. Levine, MD, Zonghong Shao, Zhizhuang Joe Zhao, PhD, Amit Verma, Pearlie K Epling-Burnette, PhD

Blood (2015) 126 (23): 603.

https://doi.org/10.1182/blood.V126.23.603.603

Published: 2015

NARROW

The Protective Role of Tubular Epithelial Cells Produced Fms-like Tyrosine Kinase Receptor 3 Ligand in Acute Kidney Injury

The Tubular Cells Produce Fms-like Tyrosine Kinase Receptor 3 Ligand to Recover Kidney Function after Acute Kidney Injury Disease

Niclosamide Inhibits the Growth of Acute Lymphoblastic Leukemia Cells By Increasing Intracellular ROS and Activation of p53-PUMA/NOXA

Aurora Kinase B/C Inhibitor GSK1070916 Specifically Targets Juvenile Myelomonocytic Leukemia Cells with SHP2(PTPN11) Mutation

Novel Anti-CD117 Antibodies for Rapid and Efficient Hematopoietic Stem Cell Depletion and Safe Bone Marrow Conditioning

HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression

Establishment of Stable Cell Lines Representing Juvenile Myelomonocytic Leukemia with SHP2 Mutations

Small Molecule Kinase Inhibitor Sunitinib Specifically Targets Juvenile Myelomonocytic Leukemia Cells with SHP2(PTPN11) Mutation

FLT3 Inhibitors Induce p53 Instability Due to Increased Interaction between p53 and MDM2 By Inhibiting STAT5 Phosphorylation in Acute Myeloid Leukemia

HMGA1 Chromatin Regulators Drive Progression in Myeloproliferative Neoplasms through Epigenetic Rewiring to Induce Networks Involved in GATA2 and Proliferation

FLT3 Inhibitors Induce Instability of p53 By Mir-181 Mediated Downregulation of Deubiquitinase YOD1 in Acute Myeloid Leukemia

FLT3 Ligand-DM1 Conjugate Selectively Targets Acute Myeloid Leukemia Cells with FLT3 Expression

Tumor Associated Macrophages Express High-Levels of FLT3 Ligand, Which Induces Activation of FLT3 Signaling That Promotes Survival of Neoplastic Cells in B-Cell Acute Lymphoblastic Leukemia

Development of Liver-Specific Thrombopoietin Targeted Sirnas: Impact on Platelet Count, Megakaryocyte Mass, and Hematopoietic Progenitors in Normal and MPN Murine Models

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Mechanism of Escape from LNK Negative Regulation: Constitutively Active JAK2V617F Retains Lysine63-Ubiquitin

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

Modulating Hedgehog Signaling Reduces MAPK, TGF-β, and Marrow Fibrosis in a Transgenic Mouse Model of JAK2V617F Associated Myeloproliferative Disease

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

Preclinical Efficacy of TGF-Beta Receptor I Kinase Inhibitor, Galunisertib, in Myelofibrosis

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American Society of Hematology

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American Society of Hematology

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