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Journal Articles

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Blood (2020) 136 (5): 596–609.

https://doi.org/10.1182/blood.2019003636

Published: 2020

Includes: Supplemental data

Journal Articles

Global Transcriptome Profiling Identifies a Key Mir-185-PAK6 Axis That Promotes Survival of Leukemic Stem Cells and Drug-Insensitive Blasts in BCR-ABL + Human Leukemia

Andrew Wu, BSc, Lin Hanyang, PhD, Katharina Rothe, PhD, Min Chen, MD PhD, Jens Ruschmann, PhD, Oleh Petriv, PhD, Kieran O'Neill, PhD, Tobias Maetzig, MD, David Knapp, PhD, Naoto Nakamichi, MD PhD, Ryan Brinkman, PhD, Inanc Birol, PhD, Donna L Forrest, MD, Carl Hansen, PhD, R. Keith Humphries, MD PhD, Connie J. Eaves, PhD, Xiaoyan Jiang, MD PhD

Blood (2018) 132 (Supplement 1): 931.

https://doi.org/10.1182/blood-2018-99-113559

Published: 2018

Journal Articles

The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia

Blood (2016) 128 (22): 1534.

https://doi.org/10.1182/blood.V128.22.1534.1534

Published: 2016

Journal Articles

The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia

Blood (2015) 126 (23): 1244.

https://doi.org/10.1182/blood.V126.23.1244.1244

Published: 2015

Journal Articles

Identification and Characterization of New Microrna Biomarkers and Target Genes in Drug-Insensitive CD34+ CML Stem/Progenitor Cells Using Global Comparative RNA-Seq Analyses

Hanyang Lin, BSc, MSc, Jonathan Zeng, Katharina Rothe, BSc, MSc, Jens Ruschmann, PhD, Oleh Petriv, PhD, Kieran O'Neill, PhD, Tobias Maetzig, PhD, David Knapp, BSc, Ryan R. Brinkman, PhD, Inanc Birol, PhD, Donna L. Forrest, MD, Carl Hansen, PhD, Connie J. Eaves, PhD, R. Keith Humphries, MD PhD, Xiaoyan Jiang, MDPhD

Blood (2015) 126 (23): 1567.

https://doi.org/10.1182/blood.V126.23.1567.1567

Published: 2015

Journal Articles

Identification of New microRNA Biomarkers and Candidate Target Genes in Primitive CML Cells Using Global Comparative RNA analyses

Hanyang Lin, Katharina Rothe, Jens Ruschmann, Oleh Petriv, Kieran O'Neill, David J.H.F. Knapp, Ryan R. Brinkman, Inanc Birol, Donna L. Forrest, MD, Carl Hansen, Connie J Eaves, R. Keith Humphries, MD PhD, Xiaoyan Jiang

Blood (2014) 124 (21): 3133.

https://doi.org/10.1182/blood.V124.21.3133.3133

Published: 2014

Journal Articles

Hoxa9/Meis1 Mediate Leukemic Programming through Microrna-155

Edith Schneider, M.Sc., Anna Staffas, PhD, Milijana Mirkovic-Hoesle, PhD, Bernhard Gentner, MD, Jens Ruschmann, Christian Buske, MD, Michael Heuser, MD, Konstanze Döhner, MD, Hartmut Döhner, MD, R. Keith Humphries, MD PhD, Arefeh Rouhi, PhD, Florian Kuchenbauer, MD PhD, Lars Palmqvist, MD PhD

Blood (2014) 124 (21): 884.

https://doi.org/10.1182/blood.V124.21.884.884

Published: 2014

Journal Articles

Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells

Blood (2011) 118 (12): 3350–3358.

https://doi.org/10.1182/blood-2010-10-312454

Published: 2011

Includes: Supplemental data

Journal Articles

Mir-223 Is Dispensable for the Onset of Acute Myeloid Leukemia

Florian Kuchenbauer, MD, PhD, Tobias Berg, MD, Sarah M Mah, Milijana mirkovic-Hosle, Anisa Salmi, Jens Ruschmann, Andrew Muranyi, Bob Agiropoulos, Arefeh Rouhi, Daniel T Starczynowski, Michael Heuser, Donna E. Hogge, MD, PhD, Fernando D. Camargo, PhD, Hartmut Dohner, MD, Christian Buske, MD, R. Keith Humphries

Blood (2010) 116 (21): 501.

https://doi.org/10.1182/blood.V116.21.501.501

Published: 2010

Journal Articles

Differential Expression of Mirna* Species in Cancer and the Contribution of MiR-223* to the Development of Acute Myeloid Leukemia.

Blood (2009) 114 (22): 2960.

https://doi.org/10.1182/blood.V114.22.2960.2960

Published: 2009

Journal Articles

Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells

Christopher J. Ong, Andrew Ming-Lum, Matt Nodwell, Ali Ghanipour, Lu Yang, David E. Williams, Joseph Kim, Loutfig Demirjian, Pooran Qasimi, Jens Ruschmann, Li-Ping Cao, Kewei Ma, Stephen W. Chung, Vincent Duronio, Raymond J. Andersen, Gerald Krystal, Alice L.-F. Mui

Blood (2007) 110 (6): 1942–1949.

https://doi.org/10.1182/blood-2007-03-079699

Published: 2007

Includes: Supplemental data

NARROW

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Global Transcriptome Profiling Identifies a Key Mir-185-PAK6 Axis That Promotes Survival of Leukemic Stem Cells and Drug-Insensitive Blasts in BCR-ABL + Human Leukemia

The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia

The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia

Identification and Characterization of New Microrna Biomarkers and Target Genes in Drug-Insensitive CD34+ CML Stem/Progenitor Cells Using Global Comparative RNA-Seq Analyses

Identification of New microRNA Biomarkers and Candidate Target Genes in Primitive CML Cells Using Global Comparative RNA analyses

Hoxa9/Meis1 Mediate Leukemic Programming through Microrna-155

Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells

Mir-223 Is Dispensable for the Onset of Acute Myeloid Leukemia

Differential Expression of Mirna* Species in Cancer and the Contribution of MiR-223* to the Development of Acute Myeloid Leukemia.

Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells

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American Society of Hematology

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American Society of Hematology

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