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Journal Articles

Damage-Induced Pyroptotic Cell Death Facilitates Regeneration of the Thymus

Sinéad Kinsella, MSc,PhD, Cindy Evandy, Kayla S Hopwo, Kirsten Cooper, Lorenzo Iovino, MD, Colton W Smith, Reema Jain, PhD, Paul DeRoos, Jarrod A Dudakov, PhD

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-143051

Published: 2020

Journal Articles

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Lorenzo Iovino, MD, Paul DeRoos, Reema Jain, PhD, Jarrod A Dudakov, PhD

Blood (2019) 134 (Supplement_1): 587.

https://doi.org/10.1182/blood-2019-131513

Published: 2019

Journal Articles

Zinc Treatment Stimulates Thymic Regeneration after Bone Marrow Transplant

Lorenzo Iovino, MD, Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Reema Jain, PhD, Paul DeRoos, Alex Gagnon, Tamas M Ugrai, Gabriele Buda, MD PhD, Sara Galimberti, MD PhD, Mario Petrini, MD PhD, Jarrod A Dudakov, PhD

Blood (2019) 134 (Supplement_1): 4422.

https://doi.org/10.1182/blood-2019-129290

Published: 2019

Journal Articles

NOD2 Acts As a Master Regulator of Endogenous Thymic Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Paul DeRoos, Reema Jain, PhD, Lorenzo Iovino, MD, Jarrod A Dudakov, PhD

Blood (2018) 132 (Supplement 1): 478.

https://doi.org/10.1182/blood-2018-99-115386

Published: 2018

Journal Articles

Zinc Supplementation Improves T Cell Reconstitution after Allogeneic HSCT By Stimulating Endogenous Pathways of Thymic Regeneration

Lorenzo Iovino, MD, Kirsten Cooper, Sinéad Kinsella, MSc, PhD, Paul DeRoos, Reema Jain, PhD, Sara Galimberti, Enrico Orciuolo, PhD MD, Edoardo Benedetti, MD, Mario Petrini, PhD MD Prof, Jarrod A Dudakov, PhD

Blood (2018) 132 (Supplement 1): 3321.

https://doi.org/10.1182/blood-2018-99-112707

Published: 2018

Journal Articles

Mechanisms Governing Endogenous Thymic Regeneration

Tobias Wertheimer, Enrico Velardi, PhD BS, Jennifer Tsai, MD PhD, Kirsten Cooper, Katja J Ottmüller, Zeinab Mokthari, Jason M. Butler, PhD, Shahin Rafii, MD, Marcel R.M. van den Brink, MD PhD, Jarrod A Dudakov, PhD

Blood (2017) 130 (Supplement 1): 66.

https://doi.org/10.1182/blood.V130.Suppl_1.66.66

Published: 2017

Journal Articles

Nrf2 Is a Critical Mediator of CD4 T Cell-Induced Acute Graft-Versus-Host Disease

Jennifer Tsai, MD PhD, Enrico Velardi, PhD BS, Yusuke Shono, MD PhD, Kimon Argyropoulos, MD, Odette M. Smith, BA, Amina Lazrak, BS, Chen Liu, MD PhD, George F Murphy, MD, Ya-Yuan Fu, PhD, Alan M. Hanash, Robert R. Jenq, MD, Jarrod A Dudakov, PhD, Marcel R.M. van den Brink, MD PhD

Blood (2017) 130 (Supplement 1): 205.

https://doi.org/10.1182/blood.V130.Suppl_1.205.205

Published: 2017

Journal Articles

The Damage Sensory Molecule TRPA1 Positively Regulates Endogenous Thymic Regeneration after Damage

Kimon Argyropoulos, MD, Enrico Velardi, PhD BS, Jennifer Tsai, MD PhD, Amina Lazrak, BS, Lorenz Jahn, PhD, Jarrod A Dudakov, PhD, Marcel R.M. van den Brink, MD PhD

Blood (2017) 130 (Supplement 1): 67.

https://doi.org/10.1182/blood.V130.Suppl_1.67.67

Published: 2017

Journal Articles

Pharmacological Inhibition of Luteinizing Hormone Signaling Promotes HSC Quiescence and Hematopoietic Regeneration

Enrico Velardi, PhD BS, Jennifer Tsai, MD PhD, Stefan Radtke, PhD, Kirsten Cooper, Kimon Argyropoulos, MD, Shieh Jae-Hung, PhD, Yusuke Shono, MD PhD, Robert R. Jenq, MD, Alan M. Hanash, Malcolm A.S. Moore, DPhil, Hans-Peter Kiem, MD PhD, Marcel R.M. van den Brink, MD PhD, Jarrod A Dudakov, PhD

Blood (2017) 130 (Supplement 1): 1139.

https://doi.org/10.1182/blood.V130.Suppl_1.1139.1139

Published: 2017

Journal Articles

Suppression of Luteinizing Hormone Enhances HSC Recovery after Hematopoietic Injuries

Enrico Velardi, PhD, Jennifer Jia-ying Tsai, PhD, Kimon V. Argyropoulos, MD, Shieh Jae-Hung, Sophie Lieberman, Fabiana Kreines, Yusuke Shono, MD PhD, Lauren Young, Tobias Wertheimer, Robert R. Jenq, MD, Alan M Hanash, MD PhD, Malcolm A.S. Moore, PhD, Marcel Van Den Brink, MD PhD, Jarrod A Dudakov, PhD

Blood (2016) 128 (22): 370.

https://doi.org/10.1182/blood.V128.22.370.370

Published: 2016

Journal Articles

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage

Blood (2015) 126 (23): 3072.

https://doi.org/10.1182/blood.V126.23.3072.3072

Published: 2015

Journal Articles

Production of BMP4 By Endothelial Cells Is Crucial for Endogenous Thymic Regeneration

Tobias Wertheimer, Enrico Velardi, PhD, Christian Brede, PhD, Shiyun Xiao, Christopher C Kloss, PhD, Andreas Beilhack, MD, Nancy Manley, PhD, Jason M. Butler, PhD, Shahin Rafii, MD, Marcel van den Brink, MD PhD, Jarrod A Dudakov, PhD

Blood (2015) 126 (23): 637.

https://doi.org/10.1182/blood.V126.23.637.637

Published: 2015

Journal Articles

Endothelial Cells Promote Endogenous Thymic Regeneration after Injury Via BMP4 Signaling

Tobias Wertheimer, Christopher Carl Kloss, PhD, Enrico Velardi, PhD, Christian Brede, PhD, Michael Ginsberg, PhD, Fabiana M Kreines, BS, Johannes L. Zakrzewski, MD, Andrea Z. Tuckett, PhD, Jennifer Jia-ying Tsai, MBChB, Odette M Smith, BA, Emily R Levy, BS, Andreas Beilhack, MD, Shahin Rafii, MD, Jason M. Butler, PhD, Marcel R.M. van den Brink, MD PhD, Jarrod A Dudakov, PhD

Blood (2014) 124 (21): 2429.

https://doi.org/10.1182/blood.V124.21.2429.2429

Published: 2014

Journal Articles

IL-22 Is an Intestinal Stem Cell Growth Factor, and IL-22 Administration in Vivo Reduces Morbidity and Mortality in Murine GvHD

Caroline A Lindemans, MD PhD, Anna Mertelsmann, Margaret Helen O'Connor, MS,BA, Jarrod A Dudakov, PhD, Robert Jenq, MD, Enrico Velardi, PhD, Lauren F. Young, BS, Odette M Smith, Gillian Lawrence, Natalie Luo, Juliet Ivanov, G Hua, PhD, Maria L Martin, Chen Liu, MD, PhD, Richard Kolesnick, MD, Marcel Van Den Brink, MD PhD, Alan M Hanash, MD PhD

Blood (2014) 124 (21): 651.

https://doi.org/10.1182/blood.V124.21.651.651

Published: 2014

Journal Articles

The Role of the Cytoplasmic RNA Sensor Retinoic Acid Inducible Gene- I (RIG-I) in Allogeneic Stem Cell Transplantation

Julius Clemens Fischer, MDcal student, Caroline A Lindemans, MD PhD, Chia-Ching Lin, PhD, Alexander Wintges, graduate student, Michael Bscheider, MD, Tobias Wertheimer, Simon Heidegger, MD, Robert Jenq, MD, Jarrod A Dudakov, PhD, Alan M. Hanash, MD PhD, Christian Peschel, MD, Tobias Haas, MD, Marcel R.M. van den Brink, MD PhD, Hendrik Poeck, MD

Blood (2014) 124 (21): 3827.

https://doi.org/10.1182/blood.V124.21.3827.3827

Published: 2014

Journal Articles

IL-22 Administration Decreases Intestinal Gvhd Pathology, Increases Intestinal Stem Cell Recovery, and Enhances Immune Reconstitution Following Allogeneic Hematopoietic Transplantation

Anna M Mertelsmann, Jarrod A Dudakov, PhD, Enrico Velardi, PhD, Guoqiang Hua, PhD, Fabiana M Kreines, BS, Emily R Levy, BS, Margaret O'Connor, Odette M Smith, BA, Richard Kolesnick, MD, Marcel R. M. van den Brink, MD, PhD, Alan M Hanash, MD, PhD

Blood (2013) 122 (21): 290.

https://doi.org/10.1182/blood.V122.21.290.290

Published: 2013

Journal Articles

Intrathymic Innate Lymphoid Cells: Long-Lived Mediators Of Immune Regeneration

Jarrod A Dudakov, PhD, Denzel Cole, Alan M Hanash, MD, PhD, Lauren F Young, BS, Fabiana M Kreines, BS, Emily R Levy, BS, Odette M Smith, BA, Enrico Velardi, PhD, Marcel van den Brink, MD, PhD

Blood (2013) 122 (21): 289.

https://doi.org/10.1182/blood.V122.21.289.289

Published: 2013

Journal Articles

Sex Steroid Blockade Enhances Thymopoiesis By Modulating Notch Signaling

Enrico Velardi, PhD, Jennifer J Tsai, M.D., Amanda M. Holland, PhD, Natalie V Singer, BS, Mallory L West, BS, Odette M Smith, BA, Lauren F. Young, BS, Fabiana M Kreines, BS, Emily R Levy, BS, Richard Boyd, PhD, Marcel R. M. van den Brink, MD, PhD, Jarrod A Dudakov, PhD

Blood (2013) 122 (21): 291.

https://doi.org/10.1182/blood.V122.21.291.291

Published: 2013

Journal Articles

Eomesodermin Regulates The Early Activation Of Alloreactive CD4 T Cells and Is Critical For Both Gvh and GVL Responses

Barbara Du Rocher, PhD, MSc, Odette M Smith, BA, Andrew M. Intlekofer, MD, PhD, Jarrod A Dudakov, PhD, Emily Levy, BA, Fabiana Kreiners, BA, Steven Reiner, Eliana Abdelhay, PhD , MSc, Marcel R.M. van den Brink, MD, PhD, Alan M Hanash, MD, PhD

Blood (2013) 122 (21): 133.

https://doi.org/10.1182/blood.V122.21.133.133

Published: 2013

Journal Articles

Innate Lymphoid Cell-Derived IL-22 Regulates Epithelial Recovery From Gvhd

Alan M Hanash, MD, PhD, Jarrod A Dudakov, PhD, Guoqiang Hua, PhD, Margaret O'Connor, Lauren F. Young, BS, Bruce R. Blazar, MD, Richard Kolesnick, MD, Marcel R.M. van den Brink, MD, PhD

Blood (2012) 120 (21): 339.

https://doi.org/10.1182/blood.V120.21.339.339

Published: 2012

NARROW

Damage-Induced Pyroptotic Cell Death Facilitates Regeneration of the Thymus

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

Zinc Treatment Stimulates Thymic Regeneration after Bone Marrow Transplant

NOD2 Acts As a Master Regulator of Endogenous Thymic Regeneration

Zinc Supplementation Improves T Cell Reconstitution after Allogeneic HSCT By Stimulating Endogenous Pathways of Thymic Regeneration

Mechanisms Governing Endogenous Thymic Regeneration

Nrf2 Is a Critical Mediator of CD4 T Cell-Induced Acute Graft-Versus-Host Disease

The Damage Sensory Molecule TRPA1 Positively Regulates Endogenous Thymic Regeneration after Damage

Pharmacological Inhibition of Luteinizing Hormone Signaling Promotes HSC Quiescence and Hematopoietic Regeneration

Suppression of Luteinizing Hormone Enhances HSC Recovery after Hematopoietic Injuries

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage

Production of BMP4 By Endothelial Cells Is Crucial for Endogenous Thymic Regeneration

Endothelial Cells Promote Endogenous Thymic Regeneration after Injury Via BMP4 Signaling

IL-22 Is an Intestinal Stem Cell Growth Factor, and IL-22 Administration in Vivo Reduces Morbidity and Mortality in Murine GvHD

The Role of the Cytoplasmic RNA Sensor Retinoic Acid Inducible Gene- I (RIG-I) in Allogeneic Stem Cell Transplantation

IL-22 Administration Decreases Intestinal Gvhd Pathology, Increases Intestinal Stem Cell Recovery, and Enhances Immune Reconstitution Following Allogeneic Hematopoietic Transplantation

Intrathymic Innate Lymphoid Cells: Long-Lived Mediators Of Immune Regeneration

Sex Steroid Blockade Enhances Thymopoiesis By Modulating Notch Signaling

Eomesodermin Regulates The Early Activation Of Alloreactive CD4 T Cells and Is Critical For Both Gvh and GVL Responses

Innate Lymphoid Cell-Derived IL-22 Regulates Epithelial Recovery From Gvhd

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American Society of Hematology

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ASH Publications

American Society of Hematology

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