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Journal Articles

Testing the Limits of Endogenous Thymic Regeneration after HCT Conditioning

Dante Dennis Acenas II, David Granadier, Lorenzo Iovino, Kirsten Cooper, Paul Deroos, Vanessa A Hernandez, Jarrod A Dudakov
Journal: Blood
Blood (2023) 142 (Supplement 1): 3427.
https://doi.org/10.1182/blood-2023-190235
Published: 2023
Journal Articles

Zinc Status Affects T Cell Reconstitution in Patients Receiving Naïve T Cell Depleted Allogeneic HSCT

Lorenzo Iovino, Jessica Lok, Jacqueline Diaz, Heather Persinger, Vanessa A Hernandez, Kirsten Cooper, Paul Deroos, David Granadier, Dante Dennis Acenas II, Jarrod A Dudakov, Marie Bleakley
Journal: Blood
Blood (2023) 142 (Supplement 1): 3562.
https://doi.org/10.1182/blood-2023-182370
Published: 2023
Journal Articles

Hematopoietic Stem Cell Transplantation (HCT) Conditioning Leads to NK Cell Cytotoxicity Limiting Endogenous Thymus Regeneration

David Granadier, Kirsten Cooper, Dante Dennis Acenas II, Lorenzo Iovino, Paul Deroos, Vanessa A Hernandez, Jarrod A Dudakov
Journal: Blood
Blood (2023) 142 (Supplement 1): 461.
https://doi.org/10.1182/blood-2023-188387
Published: 2023
Journal Articles

Interleukin 18 Suppresses Regeneration of the Thymus

David Granadier, Kirsten Cooper, Sinéad Kinsella, Cindy Evandy, Lorenzo Iovino, Paul DeRoos, Steve Shannon-Sevillano, Dante Denny Acenas, Jarrod A Dudakov
Journal: Blood
Blood (2022) 140 (Supplement 1): 1169–1170.
https://doi.org/10.1182/blood-2022-168432
Published: 2022
Journal Articles

The Zinc-Sensing Receptor GPR39 Is a Master Regulator of Immune Reconstitution after Bone Marrow Transplant in the Thymus and in the Bone Marrow

Lorenzo Iovino, Kirsten Cooper, Paul DeRoos, Cindy Evandy, David Granadier, Sinéad Kinsella, Dante Denny Acenas, Jarrod A Dudakov
Journal: Blood
Blood (2022) 140 (Supplement 1): 10206–10207.
https://doi.org/10.1182/blood-2022-162572
Published: 2022
Journal Articles

Activation of the zinc-sensing receptor GPR39 promotes T-cell reconstitution after hematopoietic cell transplant in mice

Lorenzo Iovino, Kirsten Cooper, Paul deRoos, Sinéad Kinsella, Cindy Evandy, Tamas Ugrai, Francesco Mazziotta, Kathleen S. Ensbey, David Granadier, Kayla Hopwo, Colton Smith, Alex Gagnon, Sara Galimberti, Mario Petrini, Geoffrey R. Hill, Jarrod A. Dudakov
Journal: Blood
Blood (2022) 139 (25): 3655–3666.
https://doi.org/10.1182/blood.2021013950
Published: 2022
Includes: Supplemental data
Journal Articles

Damage-Induced Pyroptotic Cell Death Facilitates Regeneration of the Thymus

Sinéad Kinsella, MSc,PhD, Cindy Evandy, Kayla S Hopwo, Kirsten Cooper, Lorenzo Iovino, MD, Colton W Smith, Reema Jain, PhD, Paul DeRoos, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28.
https://doi.org/10.1182/blood-2020-143051
Published: 2020
Journal Articles

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Lorenzo Iovino, MD, Paul DeRoos, Reema Jain, PhD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 587.
https://doi.org/10.1182/blood-2019-131513
Published: 2019
Journal Articles

Zinc Treatment Stimulates Thymic Regeneration after Bone Marrow Transplant

Lorenzo Iovino, MD, Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Reema Jain, PhD, Paul DeRoos, Alex Gagnon, Tamas M Ugrai, Gabriele Buda, MD PhD, Sara Galimberti, MD PhD, Mario Petrini, MD PhD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4422.
https://doi.org/10.1182/blood-2019-129290
Published: 2019
Journal Articles

NOD2 Acts As a Master Regulator of Endogenous Thymic Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Paul DeRoos, Reema Jain, PhD, Lorenzo Iovino, MD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 478.
https://doi.org/10.1182/blood-2018-99-115386
Published: 2018
Journal Articles

Zinc Supplementation Improves T Cell Reconstitution after Allogeneic HSCT By Stimulating Endogenous Pathways of Thymic Regeneration

Lorenzo Iovino, MD, Kirsten Cooper, Sinéad Kinsella, MSc, PhD, Paul DeRoos, Reema Jain, PhD, Sara Galimberti, Enrico Orciuolo, PhD MD, Edoardo Benedetti, MD, Mario Petrini, PhD MD Prof, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3321.
https://doi.org/10.1182/blood-2018-99-112707
Published: 2018
Journal Articles

Pharmacological Inhibition of Luteinizing Hormone Signaling Promotes HSC Quiescence and Hematopoietic Regeneration

Enrico Velardi, PhD BS, Jennifer Tsai, MD PhD, Stefan Radtke, PhD, Kirsten Cooper, Kimon Argyropoulos, MD, Shieh Jae-Hung, PhD, Yusuke Shono, MD PhD, Robert R. Jenq, MD, Alan M. Hanash, Malcolm A.S. Moore, DPhil, Hans-Peter Kiem, MD PhD, Marcel R.M. van den Brink, MD PhD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1139.
https://doi.org/10.1182/blood.V130.Suppl_1.1139.1139
Published: 2017
Journal Articles

Mechanisms Governing Endogenous Thymic Regeneration

Tobias Wertheimer, Enrico Velardi, PhD BS, Jennifer Tsai, MD PhD, Kirsten Cooper, Katja J Ottmüller, Zeinab Mokthari, Jason M. Butler, PhD, Shahin Rafii, MD, Marcel R.M. van den Brink, MD PhD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 66.
https://doi.org/10.1182/blood.V130.Suppl_1.66.66
Published: 2017