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Journal Articles

Epigenetic Silencing of BRCA1 Is Linked to Homologous Recombination Repair Defects and Elevated Mir-155 Expression in Myeloid Neoplasms

Weijie Poh, BS, Alison R Moliterno, MD, Keith W. Pratz, MD, Ivana Gojo, MD, Michael A McDevitt, MD PhD, James G. Herman, MD

Blood (2014) 124 (21): 3525.

https://doi.org/10.1182/blood.V124.21.3525.3525

Published: 2014

Journal Articles

Pcft Is Silenced By DNA Methylation In Pediatric Acute Lymphoblastic Leukemia Resulting In Decreased Methotrexate Uptake

Calvin K. Lee, MD, Weijie Poh, Megan Healey, PhD, Eric S Schafer, MD, Patrick Brown, MD, James G. Herman, MD

Blood (2013) 122 (21): 3768.

https://doi.org/10.1182/blood.V122.21.3768.3768

Published: 2013

Journal Articles

A Phase I Study Of The Histone Deacetylase Inhibitor Entinostat Plus Clofarabine For Philadelphia Chromosome Negative, Poor Risk (Newly Diagnosed Older Adults or Adults with Relapsed and Refractory Disease) Acute Lymphoblastic Leukemia Or Bilineage/Biphenotypic Leukemia

Hetty E Carraway, MD, MBA, Judith E. Karp, MD, Ivana Gojo, MD, Keith W. Pratz, MD, Nilanjan Ghosh, MD, PhD, Steven D. Gore, MD, Margaret M. Showel, MD, Mark Levis, MD, PhD, B. Douglas Smith, Jacqueline Greer, James G. Herman, MD, Lia Gore, MD, Min-Jung Lee, PhD, Sunmin Lee, PhD, Peter Ordentlich, PhD, Richard Piekarz, MD, PhD, Jane Trepel, PhD

Blood (2013) 122 (21): 1427.

https://doi.org/10.1182/blood.V122.21.1427.1427

Published: 2013

Journal Articles

Genetic and Epigenetic Defects in DNA Repair Lead to Synthetic Lethality of Poly (ADP-Ribose) Polymerase (PARP) Inhibitors in Aggressive Myeloproliferative Disorders

Michael A McDevitt, MD, PhD, Brian D Koh, Anand Patel, Alison R. Moliterno, MD, Weijie Poh, James G. Herman, MD, Robert L Dilley, B. Douglas Smith, M.D., Judith E. Karp, MD, Jaroslaw P Maciejewski, MD, PhD, Scott H. Kaufmann, MD, PhD, Keith W. Pratz, MD

Blood (2011) 118 (21): 400.

https://doi.org/10.1182/blood.V118.21.400.400

Published: 2011

Journal Articles

Identification of a DNA Methylation Predictive Signature of Overall Survival in Higher-Risk MDS Patients Treated with Azacitidine,

Tao Shi, PhD, Ludmila Danilova, PhD, Xiaolong Luo, PhD, Lela M. Lucy, MS, CL Beach, PharmD, Leslie Cope, PhD, James G. Herman, MD, Kyle J. MacBeth, PhD

Blood (2011) 118 (21): 3815.

https://doi.org/10.1182/blood.V118.21.3815.3815

Published: 2011

Journal Articles

Epigenetic Dysregulation of the Tissue Inhibitor of Metalloproteinases-2 Gene in Multiple Myeloma

Oliver Galm, Edgar Jost, MD, Claudia Schubert, James G. Herman, MD, Tim H Brümmendorf, Stefan Wilop, MD

Blood (2011) 118 (21): 5089.

https://doi.org/10.1182/blood.V118.21.5089.5089

Published: 2011

Journal Articles

Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies

Blood (2009) 114 (13): 2764–2773.

https://doi.org/10.1182/blood-2009-02-203547

Published: 2009

Includes: Supplemental data

Journal Articles

Progressive Chromatin Repression and Promoter Methylation of a -catenin Correlates with AML Transformation in Patients with and without 5q Deletions.

Michael McDevitt, MD, PhD, Ying Ye, MD, Mingzhou Guo, Hetty E. Carraway, MD, Oliver Galm, Judith E. Karp, Steven D. Gore, MD, Jaroslaw Maciejewski, Jeanne Kowalski, Xiao-Fei Wang, B. Douglas Smith, MD, James G. Herman, MD

Blood (2008) 112 (11): 3369.

https://doi.org/10.1182/blood.V112.11.3369.3369

Published: 2008

Journal Articles

Differences in Promoter Methylation of Tumor Suppressor Genes in Cytogenetically Normal and Abnormal Acute Myeloid Leukemias.

Elizabeth A. Griffiths, MD, Craig M. Hooker, MPH, Michael A. McDevitt, MD, PhD, Judith E. Karp, MD, James G. Herman, MD, Hetty E. Carraway, MD

Blood (2008) 112 (11): 2249.

https://doi.org/10.1182/blood.V112.11.2249.2249

Published: 2008

Journal Articles

Acute Myeloid Leukemia Is Characterized by Wnt Pathway Inhibitor Promoter Methylation.

Elizabeth A. Griffiths, MD, Craig M. Hooker, MPH, Michael A. McDevitt, MD, PhD, Judith E. Karp, MD, James G. Herman, MD, Hetty E. Carraway, MD

Blood (2008) 112 (11): 2253.

https://doi.org/10.1182/blood.V112.11.2253.2253

Published: 2008

Journal Articles

a-catenin Hypermethylation Correlates with AML Transformation in Patients with and without 5q Defects.

Ying Ye, Michael McDevitt, Mingzhou Guo, Judith E. Karp, Steve Gore, Hetty Carraway, Xiaofei Wang, Oliver Galm, Jaroslaw Maciejewski, Andrew Dunbar, Lukasz Gondek, Doug B. Smith, Steve Allen, Craig Hooker, James G. Herman

Blood (2007) 110 (11): 2119.

https://doi.org/10.1182/blood.V110.11.2119.2119

Published: 2007

Journal Articles

Epigenetic Inactivation of the Secreted Frizzled-Related Protein Gene Family in Multiple Myeloma.

Edgar Jost, MD, Deniz Gezer, Stefan Wilop, MD, James G. Herman, MD, Rainhardt Osieka, MD, Oliver Galm, MD

Blood (2007) 110 (11): 2131.

https://doi.org/10.1182/blood.V110.11.2131.2131

Published: 2007

Journal Articles

Aberrant DNA Methylation of the C/EBPalpha Promoter Region in Hematopoietic Malignancies.

Edgar Jost, MD, Nicole do, James G. Herman, MD, Rainhardt Osieka, MD, Oliver Galm, MD

Blood (2005) 106 (11): 4236.

https://doi.org/10.1182/blood.V106.11.4236.4236

Published: 2005

Journal Articles

Changes in Promoter Methylation and Gene Expression in Patients with MDS and MDS-AML Treated with 5-Azacitidine and Sodium Phenylbutyrate.

Steven D. Gore, MD, Stephen B. Baylin, MD, Tianna Dauses, RN, Michael R. Grever, MD, Anchalee Jiemjit, MS, Jasper Manning, MS, Carole B. Miller, MD, Anthony J. Murgo, MD, James A. Zwiebel, MD, James G. Herman, MD

Blood (2004) 104 (11): 469.

https://doi.org/10.1182/blood.V104.11.469.469

Published: 2004

Journal Articles

Aberrant DNA Methylation Patterns in Chronic Idiopathic Myelofibrosis.

Edgar Jost, M.D., Gerald Gehbauer, M.D., Christoph E. Maintz, M.D., Peter Jousten, M.D., Leo Habets, M.D., James G. Herman, M.D., Rainhardt Osieka, M.D., Oliver Galm, M.D.

Blood (2004) 104 (11): 2443.

https://doi.org/10.1182/blood.V104.11.2443.2443

Published: 2004

Journal Articles

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

Oliver Galm, Hirohide Yoshikawa, Manel Esteller, Rainhardt Osieka, James G. Herman

Blood (2003) 101 (7): 2784–2788.

https://doi.org/10.1182/blood-2002-06-1735

Published: 2003

Journal Articles

CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas

Frederic Tort, Silvia Hernàndez, Silvia Beà, Antonio Martı́nez, Manel Esteller, James G. Herman, Xavier Puig, Emma Camacho, Montse Sánchez, Iracema Nayach, Armando Lopez-Guillermo, Pedro L. Fernández, Dolors Colomer, Luis Hernàndez, Elias Campo

Blood (2002) 100 (13): 4602–4608.

https://doi.org/10.1182/blood-2002-04-1078

Published: 2002

Journal Articles

p15 INK4B CpG Island Methylation in Primary Acute Leukemia Is Heterogeneous and Suggests Density as a Critical Factor for Transcriptional Silencing

Elizabeth E. Cameron, Stephen B. Baylin, James G. Herman

Blood (1999) 94 (7): 2445–2451.

https://doi.org/10.1182/blood.V94.7.2445.419k19_2445_2451

Published: 1999

Journal Articles

Hypermethylation of the DAP-Kinase CpG Island Is a Common Alteration in B-Cell Malignancies

Rachel A. Katzenellenbogen, Stephen B. Baylin, James G. Herman

Blood (1999) 93 (12): 4347–4353.

https://doi.org/10.1182/blood.V93.12.4347

Published: 1999

NARROW

Epigenetic Silencing of BRCA1 Is Linked to Homologous Recombination Repair Defects and Elevated Mir-155 Expression in Myeloid Neoplasms

Pcft Is Silenced By DNA Methylation In Pediatric Acute Lymphoblastic Leukemia Resulting In Decreased Methotrexate Uptake

A Phase I Study Of The Histone Deacetylase Inhibitor Entinostat Plus Clofarabine For Philadelphia Chromosome Negative, Poor Risk (Newly Diagnosed Older Adults or Adults with Relapsed and Refractory Disease) Acute Lymphoblastic Leukemia Or Bilineage/Biphenotypic Leukemia

Genetic and Epigenetic Defects in DNA Repair Lead to Synthetic Lethality of Poly (ADP-Ribose) Polymerase (PARP) Inhibitors in Aggressive Myeloproliferative Disorders

Identification of a DNA Methylation Predictive Signature of Overall Survival in Higher-Risk MDS Patients Treated with Azacitidine,

Epigenetic Dysregulation of the Tissue Inhibitor of Metalloproteinases-2 Gene in Multiple Myeloma

Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies

Progressive Chromatin Repression and Promoter Methylation of a -catenin Correlates with AML Transformation in Patients with and without 5q Deletions.

Differences in Promoter Methylation of Tumor Suppressor Genes in Cytogenetically Normal and Abnormal Acute Myeloid Leukemias.

Acute Myeloid Leukemia Is Characterized by Wnt Pathway Inhibitor Promoter Methylation.

a-catenin Hypermethylation Correlates with AML Transformation in Patients with and without 5q Defects.

Epigenetic Inactivation of the Secreted Frizzled-Related Protein Gene Family in Multiple Myeloma.

Aberrant DNA Methylation of the C/EBPalpha Promoter Region in Hematopoietic Malignancies.

Changes in Promoter Methylation and Gene Expression in Patients with MDS and MDS-AML Treated with 5-Azacitidine and Sodium Phenylbutyrate.

Aberrant DNA Methylation Patterns in Chronic Idiopathic Myelofibrosis.

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas

p15 INK4B CpG Island Methylation in Primary Acute Leukemia Is Heterogeneous and Suggests Density as a Critical Factor for Transcriptional Silencing

Hypermethylation of the DAP-Kinase CpG Island Is a Common Alteration in B-Cell Malignancies

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American Society of Hematology

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American Society of Hematology

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