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JANET D. ROWLEY
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Journal Articles

MLL-Rearranged Acute Myeloid Leukemias Drive Expression Of Mir-9, a Critical Oncogene In Leukemogenesis

Colles Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Rejani B. Kunjamma, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2013) 122 (21): 3740.
https://doi.org/10.1182/blood.V122.21.3740.3740
Published: 2013
Journal Articles

PBX3 is an important cofactor of HOXA9 in leukemogenesis

Zejuan Li, Zhiyu Zhang, Yuanyuan Li, Stephen Arnovitz, Ping Chen, Hao Huang, Xi Jiang, Gia-Ming Hong, Rejani B. Kunjamma, Haomin Ren, Chunjiang He, Chong-Zhi Wang, Abdel G. Elkahloun, Peter J. M. Valk, Konstanze Döhner, Mary Beth Neilly, Lars Bullinger, Ruud Delwel, Bob Löwenberg, Paul P. Liu, Richard Morgan, Janet D. Rowley, Chun-Su Yuan, Jianjun Chen
Journal: Blood
Blood (2013) 121 (8): 1422–1431.
https://doi.org/10.1182/blood-2012-07-442004
Published: 2013
Includes: Supplemental data
Journal Articles

A Critical Role of Mir-9 in Myelopoesis and EVI1-Induced Leukemogenesis.

Vitalyi Senyuk, PhD, Yunyuan Zhang, Yang Liu, Ming Ming, PhD, Jianjun Chen, PhD, Janet D. Rowley, MD, Giuseppina Nucifora, PhD, Zhijian Qian, PhD
Journal: Blood
Blood (2012) 120 (21): 2332.
https://doi.org/10.1182/blood.V120.21.2332.2332
Published: 2012
Journal Articles

The HOXA/PBX3 Pathway Is an Attractive Therapeutic Target in MLL -Rearranged Acute Leukemia

Zejuan Li, MD, PhD, Zhiyu Zhang, Yuanyuan Li, Stephen Arnovitz, Ping Chen, MD, Hao Huang, PhD, Xi Jiang, PhD, Gia-Ming Hong, PhD, Chunjiang He, PhD, Chong-Zhi Wang, Abdel Elkahloun, PhD, Peter J. M. Valk, PhD, Konstanze Dohner, MD, PhD, Mary Beth Neilly, Lars Bullinger, MD, PhD, Ruud Delwel, PhD, Bob Lowenberg, MD, PhD, Pu Paul Liu, MD, PhD, Richard Morgan, Janet D. Rowley, MD, Chun-Su Yuan, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 3522.
https://doi.org/10.1182/blood.V120.21.3522.3522
Published: 2012
Journal Articles

Blockade of Mir-150 Maturation by MLL -Fusion/MYC/Lin-28 Is Required for MLL -Associated Leukemia

Xi Jiang, PhD, Hao Huang, PhD, Zejuan Li, MD, PhD, Yuanyuan Li, Xiao Wang, Sandeep Gurbuxani, MBBS, PhD, Ping Chen, MD, Chunjiang He, PhD, Dewen You, PhD, Shuodan Zhang, Jinhua Wang, Stephen Arnovitz, Abdel Elkahloun, PhD, Colles Price, Gia-Ming Hong, PhD, Haomin Ren, Rejani B. Kunjamma, Mary Beth Neilly, Richard A. Larson, MD, Michelle M. Le Beau, PhD, Robert K. Slany, PhD, Paul P. Liu, MD, PhD, Jun Lu, PhD, Jiwang Zhang, MD, PhD, Chuan He, PhD, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 3499.
https://doi.org/10.1182/blood.V120.21.3499.3499
Published: 2012
Journal Articles

MLL-Associated Leukemias Drive Expression of MiR-9, Required for Tumorigenesis

Colles Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Rejani B. Kunjamma, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 525.
https://doi.org/10.1182/blood.V120.21.525.525
Published: 2012
Journal Articles

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML

Zejuan Li, Hao Huang, Yuanyuan Li, Xi Jiang, Ping Chen, Stephen Arnovitz, Michael D. Radmacher, Kati Maharry, Abdel Elkahloun, Xinan Yang, Chunjiang He, Miao He, Zhiyu Zhang, Konstanze Dohner, Mary Beth Neilly, Colles Price, Yves A. Lussier, Yanming Zhang, Richard A. Larson, Michelle M. Le Beau, Michael A. Caligiuri, Lars Bullinger, Peter J. M. Valk, Ruud Delwel, Bob Lowenberg, Paul P. Liu, Guido Marcucci, Clara D. Bloomfield, Janet D. Rowley, Jianjun Chen
Journal: Blood
Blood (2012) 119 (10): 2314–2324.
https://doi.org/10.1182/blood-2011-10-386235
Published: 2012
Includes: Supplemental data
Journal Articles

Activation of a Mir-181-Targeting HOXA-PBX3 Homeobox Gene Signature Is Associated with Adverse Prognosis of Cytogenetically Abnormal Acute Myeloid Leukemia

Zejuan Li, MD, PhD, Hao Huang, PhD, Yuanyuan Li, Xi Jiang, PhD, Ping Chen, MD, Stephen Arnovitz, Michael D. Radmacher, PhD, Kati Maharry, MAS, Abdel Elkahloun, Xinan Yang, Chunjiang He, PhD, Colles O. Price, Konstanze Dohner, MD, PhD, Zhiyu Zhang, Chen Shen, Mary Beth Neilly, Yves A Lussier, Yanming Zhang, MD, Richard A. Larson, MD, Michelle M. Le Beau, PhD, Michael A Caligiuri, MD, Lars Bullinger, Peter Valk, Ruud Delwel, Ph.D., Bob Lowenberg, MD, PhD, Paul P. Liu, Guido Marcucci, MD, Clara D. Bloomfield, MD, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 236.
https://doi.org/10.1182/blood.V118.21.236.236
Published: 2011
Journal Articles

MLL-Rearrangements Result in Upregulation of Mir-9 and Subsequent Inhibition of the Tumor Suppressor TGFBI

Colles O. Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 2453.
https://doi.org/10.1182/blood.V118.21.2453.2453
Published: 2011
Journal Articles

Repression of Mir-495, a Microrna Associated with Favorable Outcome of Acute Myeloid Leukemia Patients, Is Required for the MLL -Associated Leukemogenesis,

Xi Jiang, PhD, Hao Huang, PhD, Zejuan Li, MD, PhD, Yuanyuan Li, Ping Chen, MD, Chunjiang He, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 3462.
https://doi.org/10.1182/blood.V118.21.3462.3462
Published: 2011
Journal Articles

Targeting mutations predictably

Hans Schreiber, Janet D. Rowley, Donald A. Rowley
Journal: Blood
Blood (2011) 118 (4): 830–831.
https://doi.org/10.1182/blood-2011-06-357541
Published: 2011
Journal Articles

Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

Relja Popovic, Laurie E. Riesbeck, Chinavenmeni S. Velu, Aditya Chaubey, Jiwang Zhang, Nicholas J. Achille, Frank E. Erfurth, Katherine Eaton, Jun Lu, H. Leighton Grimes, Jianjun Chen, Janet D. Rowley, Nancy J. Zeleznik-Le
Journal: Blood
Blood (2009) 113 (14): 3314–3322.
https://doi.org/10.1182/blood-2008-04-154310
Published: 2009
Journal Articles

Identification of Genes Deregulated in Both Human and Murine MLLRearrangement Leukemias.

Zejuan Li, MD, PhD, Roger T. Luo, Shuangli Mi, Miao Sun, Ping Chen, Mary Beth Neilly, Yanming Zhang, Janet D. Rowley, Michael J. Thirman, Jianjun Chen
Journal: Blood
Blood (2008) 112 (11): 3359.
https://doi.org/10.1182/blood.V112.11.3359.3359
Published: 2008
Journal Articles

Chromosomal translocations: revisited yet again

Janet D. Rowley
Journal: Blood
Blood (2008) 112 (6): 2183–2189.
https://doi.org/10.1182/blood-2008-04-097931
Published: 2008
Journal Articles

MicroRNA Expression Signatures Accurately Discriminate Acute Lymphoblastic Leukemia from Acute Myeloid Leukemia.

Shuangli Mi, PhD, Jun Lu, Ph.D., Miao Sun, M.S., Zejuan Li, Ph.D., Hao Zhang, M.S., Mary Beth Neilly, M.S., Yungui Wang, Ph.D., Zhijian Qian, Ph.D., Jie Jin, M.D., Yanming Zhang, M.D., Stefan K. Bohlander, M.D., Michelle M. Le, B.A., Richard Larson, M.D., Todd R. Golub, M.D., Janet D. Rowley, M.D., Jianjun Chen, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 231.
https://doi.org/10.1182/blood.V110.11.231.231
Published: 2007
Journal Articles

MicroRNA Expression Profiles in Acute Myeloid Leukemia with Common Translocations.

Zejuan Li, MD, PhD, Jun Lu, PhD, Miao Sun, MS, Shuangli Mi, PhD, Hao Zhang, MS, Roger T. Luo, PhD, Zhijian Qian, PhD, Mary Beth Neilly, MS, Yungui Wang, PhD, Jie Jin, MD, Yanming Zhang, MD, Stefan K. Bohlander, MD, Richard Larson, MD, Michelle LeBeau, PhD, Michael J. Thirman, MD, Todd R. Golub, MD, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2007) 110 (11): 3181.
https://doi.org/10.1182/blood.V110.11.3181.3181
Published: 2007
Journal Articles

MEL1 at 1p36.3 Is Fused to Several Partner Genes Including HOXA9 Located at Different Chromosomal Bands from 3q21.3 in t(1;3)(p36.3;q21.3)-Leukemia.

Phan Thi Xinh, MD, PhD, Hoang Anh, VU, M.D, Ph.D, Hideo Tanaka, M.D, Ph.D, Shin Fujisawa, M.D, Ph.D, Fumitoshi Taketazu, M.D, Ph.D, Janet D. Rowley, M.D, Katsushi Tokunaga, Ph.D, Yuko Sato, M.D, Ph.D
Journal: Blood
Blood (2007) 110 (11): 3499.
https://doi.org/10.1182/blood.V110.11.3499.3499
Published: 2007
Journal Articles

Identification of Genes Abnormally Expressed in Human MLL-AF4 Leukemia.

Shuangli Mi, PhD, Miao Sun, M.S., Zejuan Li, M.D., Ph.D., Roger T. Luo, Ph.D., Nimanthi Jayathilaka, B.S., Mary Beth Neilly, M.S., Masha Kocherginsky, Ph.D., Yanming Zhang, M.D. Ph.D., Sanggyu Lee, Ph.D., Theodore G. Karrison, Ph.D., Michael J. Thirman, M.D., San Ming Wang, Ph.D., Janet D. Rowley, M.D., Jianjun Chen, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 4314.
https://doi.org/10.1182/blood.V108.11.4314.4314
Published: 2006
Journal Articles

Activation-Induced Cytidine Deaminase Acts as a Mutator in BCR-ABL1 -Transformed Acute Lymphoblastic Leukemia Cells.

Niklas Feldhahn, PhD, Florian Klein, MD, Wolf-Karsten Hofmann, MD, Janet D. Rowley, MD, Hassan Jumaa, PhD, Markus Müschen, MD
Journal: Blood
Blood (2006) 108 (11): 640.
https://doi.org/10.1182/blood.V108.11.640.640
Published: 2006
Journal Articles

Identification of Genes Abnormally Expressed in Both Human and Murine MLL-ELL and/or MLL-ENL Leukemia.

Zejuan Li, MD, PhD, Miao Sun, M.S., Shuangli Mi, Ph.D., Roger T. Luo, Ph.D., Jingyue Bao, Ph.D., MeryBeth Neilly, M.S., Nimanthi Jayathilaka, B.S., Yanming Zhang, M.D., Ph.D., Deborah S. Johnson, M.S., Lili Wang, M.S., Catherine Lavau, M.D., Charles Tseng, Ph.D., Xiuqing Zhang, Ph.D., Jian Wang, Ph.D., Jun Yu, Ph.D., Huanming Yang, Ph.D., Michael J. Thirman, M.D., San Ming Wang, Ph.D., Janet D. Rowley, M.D., Jianjun Chen, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2249.
https://doi.org/10.1182/blood.V108.11.2249.2249
Published: 2006