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J.F San Miguel
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Journal Articles

Mutational Profile and Prognostic Relevance of Circulating Tumor Cells in Multiple Myeloma

Yuji Mishima, PhD, Bruno Paiva, PhD, Jiantao Shi, Mira Massoud, Salomon Manier, MD, Ludmila Flores, Adriana Perilla-Glen, MBA, Yosra Aljawai, MSc, Daisy Huynh, BS, MS, Satoshi Takagi, PhD, Aldo M Roccaro, MD PhD, Antonio Sacco, BS, Diego Alignani, Maria Victoria Mateos, Joan Bladé, MD, Juan Jose Lahuerta, Paul G. Richardson, MD, Jacob P. Laubach, MD, Robert L. Schlossman, MD, Kenneth C Anderson, MD, Nikhil C. Munshi, MD, Felipe Prosper, MD, Franziska Michor, PhD, J.F. San Miguel, Irene M. Ghobrial, MD
Journal: Blood
Blood (2015) 126 (23): 23.
https://doi.org/10.1182/blood.V126.23.23.23
Published: 2015
Journal Articles

Analysis of Zoledronic ACID Therapy for Patients with Multiple Myeloma with Asymptomatic Biochemical Relaps.

Ramón García-Sanz, Albert Oriol, Javier De La Rubia, MD, Luis Palomera, MD, Paz Ribas, Miguel Teodoro Hernández, Maria José Moreno, Joan Bargay, Angel Ramírez, Ana Isabel Teruel, María Jesús Blanchard, Mercedes Gironella, MD, Miquel Granell, MD, Eugenia Abella, J.F. San Miguel
Journal: Blood
Blood (2012) 120 (21): 2967.
https://doi.org/10.1182/blood.V120.21.2967.2967
Published: 2012
Journal Articles

A Novel Murine Model of Human Disseminated Multiple Myeloma with A Subcutaneous Human Bone Chip from an Adult Donor Confers Proliferative Advantage and Is Suitable for the In Vivo Evaluation of Novel Drugs

Enrique M. Ocio, Laura San-Segundo, Juan Blanco, Teresa Hernández-Iglesias, Diego Fernández-Lázaro, Teresa Paíno, Mercedes Garayoa, Enrique Álava, Fernando Jiménez-Barredo, Elena Díaz-Rodríguez, Atanasio Pandiella, J.F San Miguel
Journal: Blood
Blood (2010) 116 (21): 4077.
https://doi.org/10.1182/blood.V116.21.4077.4077
Published: 2010
Journal Articles

Zalypsis Has Synergistic Effect When Combined with Bortezomib + Dexamethasone through Caspase Dependent and Mainly Independent Mechanisms and through A Potent Induction of DNA Damage

Enrique M. Ocio, Lorena González-Coco, Laura San-Segundo, Xi Chen, Teresa Hernández-Iglesias, Diego Fernández-Lázaro, Teresa Paíno, Mercedes Garayoa, Carmen Cuevas, Pablo Avilés, Enrique Álava, Atanasio Pandiella, J.F San Miguel
Journal: Blood
Blood (2010) 116 (21): 3003.
https://doi.org/10.1182/blood.V116.21.3003.3003
Published: 2010
Journal Articles

Long Term Significance of Response in Multiple Myeloma After Stem Cell Transplantation.

Joaquin Martínez-López, Joan Blade, M. Carmen Gomez del Castillo, Maria Victoria Mateos, Adrian Alegre, MD, José Garcia-Laraña, Anna Sureda, Javier de la Rubia, Eulogio Conde, MD, Rafael Martínez, Felipe de Arriba, Jose Luis Gomez Zamudio, Juan Besalduch, Rafael Cabrera, M. Cruz Biguria, Jose Maria Moraleda, J.F San Miguel, Juan José Lahuerta, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1811.
https://doi.org/10.1182/blood.V114.22.1811.1811
Published: 2009
Journal Articles

Value of Gene Expression Profiling by Taqman® Low Density Arrays in the Diagnosis and Prognosis of Acute Myeloid Leukemia.

Carmen Chillon, Carlos Santamaria, Ramon Garcia-Sanz, Montserrat Hernandez, Norma C. Gutiérrez, Dolores Caballero, Maria-Belén Vidriales, Cristina Pérez, Ana Balanzategui, Miguel Alcoceba, Maria E. Sarasquete, Noemi Puig, Fernando Ramos, Alfonso García de Coca, Joaquin Díaz-Mediavilla, J.F San Miguel, Marcos Gonzalez
Journal: Blood
Blood (2009) 114 (22): 1620.
https://doi.org/10.1182/blood.V114.22.1620.1620
Published: 2009
Journal Articles

Bortezomib (Velcade)-Melphalan-Prednisone (VMP) Versus Velcade- Thalidomide-Prednisone (VTP) in Elderly Untreated Multiple Myeloma Patients: Which Is the Best Partner for Velcade: An Alkylating or An Immunomodulator Agent?

Maria-Victoria Mateos, Albert Oriol, Joaquín Martínez, Ma Teresa Cibeira, Raquel de Paz, Ma José Terol, José García-Laraña, Enrique Bengoechea, Rafael Martínez, Alejandro Martin, Felipe de Arriba, Luis Palomera, José Hernández, Jose-Luis Bello, María-Luisa Martín, Yolanda González, Joan Blade, MD, Juan José Lahuerta, J.F San Miguel, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 651.
https://doi.org/10.1182/blood.V112.11.651.651
Published: 2008
Journal Articles

Thalidomide/Dexamethasone (TD) Vs. Bortezomib(Velcade®)/Thalidomide/Dexamethasone (VTD) Vs. VBMCP/VBAD/Velcade® As Induction Regimens Prior Autologous Stem Cell Transplantation (ASCT) in Younger Patients with Multiple Myeloma (MM): First Results of a Prospective Phase III PETHEMA/Gem Trial

Laura Rosinol, M. Teresa Cibeira, Joaquin Martinez, Maria Victoria Mateos, Ma José Terol, Javier de la Rubia, Luis Palomera, Felipe de Arriba, Albert Oriol, Adrian Alegre, Juan Besalduch, Raquel de Paz, José Garcia-Laraña, Joaquín Díaz-Mediavilla, Anna Sureda, Juan José Lahuerta, J.F. San Miguel, Joan Blade
Journal: Blood
Blood (2008) 112 (11): 654.
https://doi.org/10.1182/blood.V112.11.654.654
Published: 2008
Journal Articles

Both Expanded and Uncultured Mesenchymal Stem Cells from MDS Patients Are Genomically Abnormal, Showing a Specific Genetic Profile for the 5q- Syndrome.

Olga López Villar, MD, Juan LuíS. García, PhD, Fermín. M Sánchez Guijo, MD, PhD, Cristina Robledo, Pilar Hernandez Campo, PhD, Maria Diez Campelo, MD, PhD, Sandra Muntion, Jose Antonio Pérez Simón, MD, PhD, J.F. San Miguel, MD, PhD, MaríA. Consuelo Del Cañizo, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1650.
https://doi.org/10.1182/blood.V112.11.1650.1650
Published: 2008
Journal Articles

Effect of Pre and Post-Transplantation Responses on Outcome of Multiple Myeloma Patients: CR and near-CR Should Not Be Considered as Equivalent Prognostic Markers. Results of a PETHEMA/Gem Prospective Study

Juan José Lahuerta, Maria Victoria Mateos, Joaquin Martínez-López, Laura Rosinol, Anna Sureda, Javier de la Rubia, José García-Laraña, Rafael Martínez-Martínez, Miguel-Teodoro Hernández-García, Dolores Carrera, Juan Besalduch, MD, PhD, Felipe de Arriba, Jose-Maria Ribera, Lourdes Escoda, María-Belen Hernández-Ruiz, Javier García-Frade, Concepción Rivas-González, Adrian Alegre, Joan Blade, J.F. San Miguel
Journal: Blood
Blood (2008) 112 (11): 161.
https://doi.org/10.1182/blood.V112.11.161.161
Published: 2008
Journal Articles

Final Results of a Phase II Trial with Plitidepsin (Aplidin) Alone and in Combination with Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma

Maria-Victoria Mateos, Mª Teresa Cibeira, Paul Richardson, Joan Blade, Felipe Prosper, MD, Albert Oriol, Javier de la Rubia, MD, Adrian Alegre, MD, Juan José Lahuerta, MD, PhD, Ramón García-Sanz, MD, PhD, Constantine S. Mitsiades, MD, PhD, Jose Espinoza, MD, Kenneth C. Anderson, J.F. San Miguel
Journal: Blood
Blood (2008) 112 (11): 3700.
https://doi.org/10.1182/blood.V112.11.3700.3700
Published: 2008
Journal Articles

DNA Double Strand Breaks Induction by Zalypsis, a Novel Marine Compound, Results in Potent Antimyeloma Activity

Enrique M Ocio, Patricia Maiso, Xi Chen, Mercedes Garayoa, Stela Álvarez-Fernández, Laura San-Segundo, David Vilanova, Lucía López-Corral, Juan Carlos Montero, Teresa Hernández-Iglesias, Enrique de Álava, Carlos Galmarini, Pablo Avilés, Carmen Cuevas, Atanasio Pandiella, J.F. San Miguel, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 245.
https://doi.org/10.1182/blood.V112.11.245.245
Published: 2008
Journal Articles

A High Number of Losses in 13q14 Chromosome Is Associated with a Worse Outcome and Biological Differences in Patients with B Chronic Lymphoid Leukemia.

José-Ángel Hernández, Ana-Eugenia Rodríguez, Marcos González, Rocío Benito, Celia Fontanillo, Virgilio Sandoval, Mercedes Romero, Guillermo Martín-Núñez, Alfonso García de Coca, Rosa Fisac, Josefina Galende, Isabel Recio, Francisco Ortuño, Juan-Luis García, Javier de las Rivas, Norma-Carmen Gutiérrez, Jesús-Maria Hernández, J.F. San Miguel
Journal: Blood
Blood (2008) 112 (11): 2073.
https://doi.org/10.1182/blood.V112.11.2073.2073
Published: 2008
Journal Articles

Maintenance Treatment after Autologous Peripheral Blood Stem Cell Transplantation (PBSCT) in Multiple Myeloma (MM) with a Unique Weekly Dose of Pegylated Interpheron alpha2b (Pegintron®): Preliminary Clinical Results in 30 Patients of a Phase II Multicentric Study.

Adrian Alegre, B. Aguado, J. Garcia-Laraña, J.J. Lahuerta, M.V. Mateos, R. Rodriguez-Notario, B. Navas, J.M. Fernandez-Rañada, J.F. San Miguel
Journal: Blood
Blood (2007) 110 (11): 4822.
https://doi.org/10.1182/blood.V110.11.4822.4822
Published: 2007
Journal Articles

Non Myeloablative Allogeneic Related Transplant in Patients with Aggressive B Cell Lymphoma: Results of Two Multicenter Spanish Trials. The GELTAMO Group.

M.D. Caballero, J. Briones, M.V Mateos, J.F. Tomás, R. Martino, J. de la Serna, J.L. Díez, J.A. Pérez-Simón, A. Sureda, J. Sarrá, J. García-Laraña, J.M. Ribera, J. Sierra, J.F. San Miguel
Journal: Blood
Blood (2007) 110 (11): 5053.
https://doi.org/10.1182/blood.V110.11.5053.5053
Published: 2007
Journal Articles

Imatinib Mesilate Modifies Genes Involved in Hematopoiesis in Non Clonal Bone Marrow Cells from CML Patients in Complete Cytogenetic Response.

Fermin M. Sanchez-Guijo, MD, PhD, Eva Lumbreras, BSc, Patricia Morais, BSc, Juan-Luis Garcia, PhD, Norma C. Gutierrez, MD, PhD, J.F. San Miguel, MD, PhD, Consuelo del Canizo, MD, PhD, Jesus M. Hernandez-Rivas, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2947.
https://doi.org/10.1182/blood.V110.11.2947.2947
Published: 2007
Journal Articles

Antimyeloma Efficacy of Plitidepsin (Aplidin®): From Bench to the Bedside.

Enrique M. Ocio, Constantine Mitsiades, M. Victoria Mateos, Patricia Maiso, Faustino Mollinedo, Mercedes Garayoa, Consuelo Gajate, Joan Blade, Felipe Prosper, Juan José Lahuerta, Nicholas Mitsiades, Ciaran J. McMullan, Nikhil C. Munshi, Teru Hideshima, Dharminder Chauhan, Carmen Cuevas, Pablo Avilés, Glynn Faircloth, Paul G. Richardson, Atanasio Pandiella, Kenneth C. Anderson, J.F. San Miguel
Journal: Blood
Blood (2007) 110 (11): 1178.
https://doi.org/10.1182/blood.V110.11.1178.1178
Published: 2007
Journal Articles

Clinical Efficacy of Bortezomib Based Therapy in Plasma Cell Leukemias.

Adrian Alegre, B. Aguado, J.J. Lahuerta, C. Cervero, A. Oriol, A. Abella, R. Carrion, R. Renat, J.A. Hernandez-Rivas, J. de la Rubia, M.V. Mateos, R. Garcia-Sanz, R. Rodriguez-Notario, B. Navas, J.M. Fernandez-Rañada, J.F. San Miguel
Journal: Blood
Blood (2007) 110 (11): 2726.
https://doi.org/10.1182/blood.V110.11.2726.2726
Published: 2007
Journal Articles

Effect of Mesenchymal Stem Cells on the Viability, Proliferation and Differentiation of B Lymphocytes.

Soraya Tabera, Jose A. Perez-Simon, Maria Diez-Campelo, Luis I. Sanchez-Abarca, Belen Blanco, Ana Benito, Enrique Ocio, Fermin M. Sanchez-Guijo, Consuelo Canizo, J.F. San Miguel
Journal: Blood
Blood (2007) 110 (11): 3880.
https://doi.org/10.1182/blood.V110.11.3880.3880
Published: 2007
Journal Articles

Mesenchymal Stem Cells from Patients with Myelodysplastic Syndromes Are Functionally and Genomically Abnormal.

Olga López Villar, MD, Fermin M. Sánchez-Guijo, PhD, Juan Luis García, PhD, Jose Ramon González Porras, PhD, Eva Villarón, PhD, Natalia López-Holgado, PhD, Jose Antonio Pérez Simón, PhD, J.F. San Miguel, PhD, María Consuelo Del Cañizo, PhD
Journal: Blood
Blood (2007) 110 (11): 1916.
https://doi.org/10.1182/blood.V110.11.1916.1916
Published: 2007