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Journal Articles

Association of Liver Iron Concentration Levels with Myocardial T2* Responses in Transfusion-Dependent Thalassemia Major Patients Treated with Deferasirox and Deferoxamine- Extension of Cordelia Study

Dudley J Pennell, John B Porter, Antonio Piga, Jackie Han, Alexander Vorog, Yesim Aydinok

Blood (2015) 126 (23): 2155.

https://doi.org/10.1182/blood.V126.23.2155.2155

Published: 2015

Journal Articles

A 1-year randomized controlled trial of deferasirox vs deferoxamine for myocardial iron removal in β-thalassemia major (CORDELIA)

Dudley J. Pennell, John B. Porter, Antonio Piga, Yongrong Lai, Amal El-Beshlawy, Khawla M. Belhoul, Mohsen Elalfy, Akif Yesilipek, Yurdanur Kilinç, Tomasz Lawniczek, Dany Habr, Marianne Weisskopf, Yiyun Zhang, Yesim Aydinok

Blood (2014) 123 (10): 1447–1454.

https://doi.org/10.1182/blood-2013-04-497842

Published: 2014

Includes: Supplemental data

Journal Articles

Deferasirox Compared With Deferoxamine For The Removal Of Cardiac Iron In Patients With β-Thalassemia Major: 2-Year Data From The Cordelia Extension

Dudley J Pennell, MD, John B Porter, MD, Antonio Piga, MD, Yongrong Lai, MD, Amal El-Beshlawy, MD, Khawla Belhoul, MD, Mohsen Elalfy, MD, Akif Yesilipek, MD, Yurdanur Kilinç, MD, Antje Wegener, MD, Dany Habr, MD, Junwu Shen, PhD, Yesim Aydinok, MD

Blood (2013) 122 (21): 1018.

https://doi.org/10.1182/blood.V122.21.1018.1018

Published: 2013

Journal Articles

A Multicenter, Randomized, Open-Label Trial Evaluating Deferasirox Compared with Deferoxamine for the Removal of Cardiac Iron in Patients with β-Thalassemia Major and Iron Overload (CORDELIA).

Dudley J Pennell, MD, John B Porter, MD, Antonio Piga, MD, Yongrong Lai, MD, Amal El-Beshlawy, MD, Khawla Beloul, MD, Mohsen Elalfy, MD, Akif Yesilipek, MD, Yurdanur Kilinç, MD, Tomasz Lawniczek, MD, Dany Habr, MD, Marianne Weisskopf, PhD, Yiyun Zhang, PhD, Yesim Aydinok, MD

Blood (2012) 120 (21): 2124.

https://doi.org/10.1182/blood.V120.21.2124.2124

Published: 2012

Journal Articles

A Decade Follow-up of a Thalassemia Major (TM) Cohort Monitored by Cardiac Magnetic Resonance Imaging (CMR): Significant Reduction In Patients with Cardiac Iron and In Total Mortality

Alison S Thomas, MBBS, Maciej Garbowski, MBBS, Ai Leen Ang, MBBS, Farrukh T Shah, MBBS, MD, J. Malcolm Walker, MBBS, James C Moon, MBBCh, MD, Dudley J Pennell, MD, John B Porter, MD

Blood (2010) 116 (21): 1011.

https://doi.org/10.1182/blood.V116.21.1011.1011

Published: 2010

Journal Articles

Efficacy of deferasirox in reducing and preventing cardiac iron overload in β-thalassemia

Dudley J. Pennell, John B. Porter, Maria Domenica Cappellini, Amal El-Beshlawy, Lee Lee Chan, Yesim Aydinok, Mohsen Saleh Elalfy, Pranee Sutcharitchan, Chi-Kong Li, Hishamshah Ibrahim, Vip Viprakasit, Antonis Kattamis, Gillian Smith, Dany Habr, Gabor Domokos, Bernard Roubert, Ali Taher

Blood (2010) 115 (12): 2364–2371.

https://doi.org/10.1182/blood-2009-04-217455

Published: 2010

Journal Articles

Calibration of Improved T2* Method for the Estimation of Liver Iron Concentration in Transfusional Iron Overload.

Maciej W Garbowski, John-Paul Carpenter, Gillian Smith, Dudley J Pennell, John B Porter

Blood (2009) 114 (22): 2004.

https://doi.org/10.1182/blood.V114.22.2004.2004

Published: 2009

Journal Articles

Impact of Myocardial Iron Loading On Right Ventricular Function.

John-Paul Carpenter, Francisco Alpendurada, Monica Deac, Paul Kirk, John B Porter, J. Malcolm Walker, Winston Banya, Taigang He, Gillian Smith, Dudley J Pennell

Blood (2009) 114 (22): 2012.

https://doi.org/10.1182/blood.V114.22.2012.2012

Published: 2009

Journal Articles

Improvement in Right Ventricular Function Following 1 Year of Deferasirox Therapy in Patients with β-Thalassemia.

Gillian Smith, Dudley J. Pennell, John B. Porter, M. Domenica Cappellini, Lee Lee Chan, Amal El-Beshlawy, Yesim Aydinok, Hishamshah Ibrahim, Chi-Kong Lee, Vip Viprakasit, Mohsen Saleh Elalfy, Antonis Kattamis, Dany Habr, Gabor Domokos, Abdel Hmissi, Ali Taher

Blood (2009) 114 (22): 5106.

https://doi.org/10.1182/blood.V114.22.5106.5106

Published: 2009

Journal Articles

Efficacy and Safety of Deferasirox (Exjade®) in β-Thalassemia Patients with Myocardial Siderosis: 2-Year Results From the EPIC Cardiac Sub-Study.

Dudley J. Pennell, John B. Porter, M. Domenica Cappellini, Lee Lee Chan, Amal El-Beshlawy, Yesim Aydinok, Hishamshah Ibrahim, Chi-Kong Li, Vip Viprakasit, Mohsen Saleh Elalfy, Antonis Kattamis, Gillian Smith, Dany Habr, Gabor Domokos, Bernard Roubert, Ali Taher

Blood (2009) 114 (22): 4062.

https://doi.org/10.1182/blood.V114.22.4062.4062

Published: 2009

Journal Articles

Improved Endothelial Function with Combined Chelation Therapy in Thalassaemia Major.

Mark A. Tanner, MRCP, Renzo Galanello, MD, Carlo Dessi, MD, Annalisa Agus, MD, Gillian C. Smith, MSc, Mark A. Westwood, MD, Ravi Assomull, MRCP, Sunil V. Nair, MRCP, J. Malcolm Walker, MD, Dudley J. Pennell, MD

Blood (2006) 108 (11): 1770.

https://doi.org/10.1182/blood.V108.11.1770.1770

Published: 2006

Journal Articles

Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis

Dudley J. Pennell, Vasili Berdoukas, Markissia Karagiorga, Vasili Ladis, Antonio Piga, Athanassios Aessopos, Efstathios D. Gotsis, Mark A. Tanner, Gill C. Smith, Mark A. Westwood, Beatrix Wonke, Renzo Galanello

Blood (2006) 107 (9): 3738–3744.

https://doi.org/10.1182/blood-2005-07-2948

Published: 2006

Journal Articles

Validation of T2* Technique in Ex-Vivo Myocardial Tissue.

Paul Kirk, MBBS, BSc, MRCP, David N. Firmin, PhD, Barry Sampson, PhD, John B. Porter, MD, Malcolm J. Walker, MD, Dudley J. Pennell, MD, FRCP, FESC, FACC

Blood (2005) 106 (11): 3718.

https://doi.org/10.1182/blood.V106.11.3718.3718

Published: 2005

Journal Articles

Myocardial T2* in Patients with Cardiac Failure Secondary to Iron Overload.

Mark A. Tanner, MBBS, John B. Porter, MD, Mark A. Westwood, MD, Sunil V. Nair, MBBS, Lisa J. Anderson, MD, J. M. Walker, MD, Dudley J. Pennell, MD

Blood (2005) 106 (11): 3838.

https://doi.org/10.1182/blood.V106.11.3838.3838

Published: 2005

Journal Articles

Improved Myocardial T2* in Transfusion Dependent Anemias Receiving ICL670 (Deferasirox).

John B. Porter, MD, Mark A. Tanner, MRCP, Dudley J. Pennell, MD, Perla Eleftheriou, MD

Blood (2005) 106 (11): 3600.

https://doi.org/10.1182/blood.V106.11.3600.3600

Published: 2005

Journal Articles

Normalized Left Ventricular Volumes and Function in Thalassemia Major Patients with Normal Myocardial Iron.

Mark A. Westwood, MD, Lisa J. Anderson, MD, Alicia M. Maceira, MD, Emma Prescott, BSc, John B. Porter, PhD, Beatrix Wonke, MD, Malcolm J. Walker, MD, Dudley J. Pennell, MD

Blood (2005) 106 (11): 2707.

https://doi.org/10.1182/blood.V106.11.2707.2707

Published: 2005

Journal Articles

A Randomized, Placebo Controlled, Double Blind Trial of the Effect of Combined Therapy with Deferoxamine and Deferiprone on Myocardial Iron in Thalassaemia Major Using Cardiovascular Magnetic Resonance.

Mark A. Tanner, MD, Renzo Galanello, MD, Carlo Dessi, MD, Mark A. Westwood, MD, Gillian C. Smith, MSc, Mohammed Khan, MSc, Sunil V. Nair, MD, J. M. Walker, MD, Dudley J. Pennell, MD

Blood (2005) 106 (11): 3655.

https://doi.org/10.1182/blood.V106.11.3655.3655

Published: 2005

Journal Articles

Inter-Site Validation of a Single Breath Hold T2* MR Technique for Heart and Liver Iron Measurement.

Paul Kirk, MBBS, BSc, MRCP, Lisa J. Anderson, MD, Mark A. Tanner, MBBS, Renzo Galanello, MD, Gildo Matta, MD, Ru S. Tan, MD, Ivg Ng, MD, Angie Lai, MD, Kevin Chen, MD, David N. Firmin, MD, Dudley J. Pennell, MD, FRCP, FESC, FACC

Blood (2005) 106 (11): 3830.

https://doi.org/10.1182/blood.V106.11.3830.3830

Published: 2005

Journal Articles

The Effect of Combined Chelation Therapy in the Treatment of Severe Myocardial Iron Loading in Beta Thalassaemia Major.

Mark A. Tanner, MBBS, Renzo Galanello, MD, Carlo Dessi, MD, Mark A. Westwood, MD, Dudley J. Pennell, MD

Blood (2005) 106 (11): 3836.

https://doi.org/10.1182/blood.V106.11.3836.3836

Published: 2005

Journal Articles

Calibration of Myocardial T2* Values in Post-Mortem Hearts.

Dudley J. Pennell, MD, Lisa J. Anderson, MD, Kirk Paul, MBBS, Gian Luca Forni, MD, Gareth Ellis, MD, J. M. Walker, MD, John B. Porter, MD

Blood (2005) 106 (11): 3837.

https://doi.org/10.1182/blood.V106.11.3837.3837

Published: 2005

NARROW

Association of Liver Iron Concentration Levels with Myocardial T2* Responses in Transfusion-Dependent Thalassemia Major Patients Treated with Deferasirox and Deferoxamine- Extension of Cordelia Study

A 1-year randomized controlled trial of deferasirox vs deferoxamine for myocardial iron removal in β-thalassemia major (CORDELIA)

Deferasirox Compared With Deferoxamine For The Removal Of Cardiac Iron In Patients With β-Thalassemia Major: 2-Year Data From The Cordelia Extension

A Multicenter, Randomized, Open-Label Trial Evaluating Deferasirox Compared with Deferoxamine for the Removal of Cardiac Iron in Patients with β-Thalassemia Major and Iron Overload (CORDELIA).

A Decade Follow-up of a Thalassemia Major (TM) Cohort Monitored by Cardiac Magnetic Resonance Imaging (CMR): Significant Reduction In Patients with Cardiac Iron and In Total Mortality

Efficacy of deferasirox in reducing and preventing cardiac iron overload in β-thalassemia

Calibration of Improved T2* Method for the Estimation of Liver Iron Concentration in Transfusional Iron Overload.

Impact of Myocardial Iron Loading On Right Ventricular Function.

Improvement in Right Ventricular Function Following 1 Year of Deferasirox Therapy in Patients with β-Thalassemia.

Efficacy and Safety of Deferasirox (Exjade®) in β-Thalassemia Patients with Myocardial Siderosis: 2-Year Results From the EPIC Cardiac Sub-Study.

Improved Endothelial Function with Combined Chelation Therapy in Thalassaemia Major.

Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis

Validation of T2* Technique in Ex-Vivo Myocardial Tissue.

Myocardial T2* in Patients with Cardiac Failure Secondary to Iron Overload.

Improved Myocardial T2* in Transfusion Dependent Anemias Receiving ICL670 (Deferasirox).

Normalized Left Ventricular Volumes and Function in Thalassemia Major Patients with Normal Myocardial Iron.

A Randomized, Placebo Controlled, Double Blind Trial of the Effect of Combined Therapy with Deferoxamine and Deferiprone on Myocardial Iron in Thalassaemia Major Using Cardiovascular Magnetic Resonance.

Inter-Site Validation of a Single Breath Hold T2* MR Technique for Heart and Liver Iron Measurement.

The Effect of Combined Chelation Therapy in the Treatment of Severe Myocardial Iron Loading in Beta Thalassaemia Major.

Calibration of Myocardial T2* Values in Post-Mortem Hearts.

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American Society of Hematology

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American Society of Hematology

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