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Journal Articles

Efficacy and Safety of Combination Therapy with Oral Iron Chelators Deferiprone and Deferasirox in Patients with β-Thalassemia Major: A Systematic Literature Review

Janet L. Kwiatkowski, Sujit Sheth, Antonis Kattamis, Francesco Bianchi, Fernando Tricta, Caroline Fradette, Roberta Luzzi, Antonio Piga

Blood (2024) 144 (Supplement 1): 5268.

https://doi.org/10.1182/blood-2024-207562

Published: 2024

Journal Articles

Erythroid Response in Patients with Non-Transfusion-Dependent β-Thalassemia Treated with Luspatercept: Long-Term Data from the BEYOND Trial

Ali T. Taher, Vip Viprakasit, Maria Domenica Domenica Cappellini, Antonio Piga, John B. Porter, Thomas D. Coates, Khaled M. Musallam, Gian Luca Forni, Jeevan K. Shetty, Marija Bosilkovska Weisskopf, Richard Wei, Wen-Ling Kuo, Antonis Kattamis

Blood (2022) 140 (Supplement 1): 8210–8212.

https://doi.org/10.1182/blood-2022-157512

Published: 2022

Journal Articles

Alterations of Neuromuscular Environment Are Associated with Chronic Tissue Hypoxia in β-Thalassemia Patients

Andrea Piolatto, Gennaro Boccia, Alessandra Manca, Carmen Gaglioti, Teresa Ceglie, Caterina Cosentino, Luca Beratto, Jessica Cusato, Patrizia Falco, Silvia De Carlo, Filomena Longo, Antonella Roetto, Antonio Piga, Antonio D'Avolio, Alberto Rainoldi, Giovanni Battista Ferrero

Blood (2022) 140 (Supplement 1): 8208–8209.

https://doi.org/10.1182/blood-2022-168830

Published: 2022

Journal Articles

Effect of Luspatercept in β-Thalassemia Patients with β0/β0 Genotype: A Subgroup Analysis of the BELIEVE Study

Sujit Sheth, Olivier Hermine, Ali T. Taher, Kevin H.M. Kuo, John B. Porter, Antonio Piga, Thomas D. Coates, Antonis Kattamis, Loyse Felber Medlin, Wen-Ling Kuo, Natalia Holot, Maria Domenica Domenica Cappellini

Blood (2022) 140 (Supplement 1): 1946–1948.

https://doi.org/10.1182/blood-2022-157511

Published: 2022

Journal Articles

Mortality in β-thalassemia patients with confirmed pulmonary arterial hypertension on right heart catheterization

Valeria Maria Pinto, Khaled M. Musallam, Giorgio Derchi, Giovanna Graziadei, Marianna Giuditta, Raffaella Origa, Susanna Barella, Gavino Casu, Annamaria Pasanisi, Filomena Longo, Maddalena Casale, Roberta Miceli, Pierluigi Merella, Immacolata Tartaglione, Antonio Piga, Maria Domenica Cappellini, Barbara Gianesin, Gian Luca Forni, on behalf of the Webthal project

Blood (2022) 139 (13): 2080–2083.

https://doi.org/10.1182/blood.2021014862

Published: 2022

Journal Articles

Luspatercept Improves Quality of Life and Reduces Red Blood Cell Transfusion Burden in Patients with Non-Transfusion-Dependent β-Thalassemia in the BEYOND Trial

Antonis Kattamis, Vip Viprakasit, Maria Domenica Cappellini, Ersi Voskaridou, Antonio Piga, John B. Porter, Thomas D. Coates, Gian Luca Forni, Jeevan K. Shetty, Dimana Miteva, Oriana Esposito, Wen-Ling Kuo, Shien Guo, Christopher Pelligra, Jennifer Lord-Bessen, Aylin Yucel, Ali T. Taher

Blood (2021) 138 (Supplement 1): 3081.

https://doi.org/10.1182/blood-2021-148535

Published: 2021

Journal Articles

Serum GDF15 in β-Thalassemia: A Quantitative Marker of Ineffective Erythropoiesis?

Andrea Piolatto, Martina Teti, Nicolò Tesio, Giovanni Battista Ferrero, Antonio Piga, Filomena Longo

Blood (2021) 138 (Supplement 1): 2017.

https://doi.org/10.1182/blood-2021-145993

Published: 2021

Journal Articles

COVID 19 and Hemoglobinopathies: Update of the Italian Experience

Irene Motta, MD, Valeria Maria Pinto, MD, Filomena Longo, MD, Federico Bonetti, MD, Elisa De Michele, MD, Alberto Piperno, MD, Lorella Pitrolo, MD, Micol Quaresima, MD, Michela Ribersani, MD, Margherita Migone De Amicis, MD, Manuela Balocco, MD, Barbara Gianesin, PhD, Giovanna Graziadei, MD, Maria Domenica Cappellini, MD, Lucia De Franceschi, MD, Antonio Piga, MD, Gian Luca Forni, MD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-141610

Published: 2020

Journal Articles

Health-Related Quality of Life Outcomes for Patients with Transfusion-Dependent Beta-Thalassemia Treated with Luspatercept in the Believe Trial

Maria Domenica Cappellini, Ali T. Taher, Antonio Piga, MD, Farrukh Shah, Ersi Voskaridou, Vip Viprakasit, John B. Porter, MA, MD, FRCP, FRCPath, Olivier Hermine, Ellis J. Neufeld, Alexis A. Thompson, MD, Derek Tang, Peiwen Yu, Shien Guo, Jeevan K. Shetty, Dimana Miteva, Tatiana Zinger, Jay T. Backstrom, Esther Natalie Oliva, MD

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-136312

Published: 2020

Journal Articles

Sustained Reductions in Red Blood Cell (RBC) Transfusion Burden and Events in β-Thalassemia with Luspatercept: Longitudinal Results of the Believe Trial

Ali T. Taher, Vip Viprakasit, Olivier Hermine, John B. Porter, MA, MD, FRCP, FRCPath, Antonio Piga, MD, Kevin H.M. Kuo, MDMSc,FRCPC, Thomas D. Coates, MD, Ersi Voskaridou, Abderrahim Khelif, Antonis Kattamis, Jeevan K. Shetty, George Zhang, Yu (Olivia) Tian, Dimana Miteva, Tatiana Zinger, Derek Tang, Jay T. Backstrom, Maria Domenica Cappellini

Blood (2020) 136 (Supplement 1): 45–46.

https://doi.org/10.1182/blood-2020-140310

Published: 2020

Journal Articles

Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety Comparison of Deferasirox Formulations for Treatment Tailoring

Andrea Piolatto, MS, Carmen Gaglioti, MD, Filomena Longo, MD, Silvia De Francia, PhD, Sarah Allegra, PhD, Paola Berchialla, PhD, Antonio Piga

Blood (2019) 134 (Supplement_1): 3547.

https://doi.org/10.1182/blood-2019-122030

Published: 2019

Journal Articles

Evaluating Luspatercept Responders in the Phase 3, Randomized, Double-Blind, Placebo-Controlled BELIEVE Trial of Luspatercept in Adult Beta-Thalassemia Patients (Pts) Who Require Regular Red Blood Cell (RBC) Transfusions

Blood (2019) 134 (Supplement_1): 3545.

https://doi.org/10.1182/blood-2019-122685

Published: 2019

Journal Articles

Selecting ß-Thalassemia Patients for Gene Therapy: A Decision-Making Algorithm

Donatella Baronciani, MD, Maddalena Casale, MD, Lucia De Franceschi, MD, Giovanna Graziadei, MD, Filomena Longo, MD, Raffaella Origa, MD, Valeria Maria Pinto, MD, Paolo Rigano, MD, Monia Marchetti, MD, Antonia Gigante, Emanuele Angelucci, MD, Maria Domenica Cappellini, MD, Achille Iolascon, MD PhD, Antonio Piga, Gian Luca Forni

Blood (2019) 134 (Supplement_1): 972.

https://doi.org/10.1182/blood-2019-128320

Published: 2019

Journal Articles

Luspatercept improves hemoglobin levels and blood transfusion requirements in a study of patients with β-thalassemia

Antonio Piga, Silverio Perrotta, Maria Rita Gamberini, Ersi Voskaridou, Angela Melpignano, Aldo Filosa, Vincenzo Caruso, Antonello Pietrangelo, Filomena Longo, Immacolata Tartaglione, Caterina Borgna-Pignatti, Xiaosha Zhang, Abderrahmane Laadem, Matthew L. Sherman, Kenneth M. Attie

Blood (2019) 133 (12): 1279–1289.

https://doi.org/10.1182/blood-2018-10-879247

Published: 2019

Includes: Supplemental data

Journal Articles

Hemoglobin Utilization in Asplenic and Non-Splenectomized Transfusion Dependent Thalassemia Patients Supported with Pathogen Reduced Red Blood Cell Concentrates in a Phase 3 Study (SPARC)

Yesim Aydinok, Antonio Piga, Raffaella Origa, MD, Nina Mufti, PhD, Anna Erikson, PhD, Anne North, PhD, Katie Waldhaus, Christine Ernst, MD, Jin-Sying Lin, PhD, Norman Huang, PhD, Richard J. Benjamin, MD, Laurence Corash, MD

Blood (2018) 132 (Supplement 1): 3812.

https://doi.org/10.1182/blood-2018-99-112685

Published: 2018

Journal Articles

Liver Iron Measurements with Less Expensive Technology: Comparison of a Room-Temperature Susceptometer with SQUID in 84 Subjects

Alberto Fenzi, PhD, Filomena Longo, MD, Antonio Piga, Daniela Ventura, MD, Andrea Sboarina, PhD, Sankaran Kumar, PhD, William Avrin, PhD

Blood (2018) 132 (Supplement 1): 3628.

https://doi.org/10.1182/blood-2018-99-116955

Published: 2018

Journal Articles

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Blood (2018) 132 (Supplement 1): 163.

https://doi.org/10.1182/blood-2018-163

Published: 2018

Journal Articles

Renal Safety after More Than a Decade of Deferasirox Use in Patients with Transfusional Hemosiderosis

Raffaella Origa, Antonio Piga, MD, Immacolata Tartaglione, MD, Giuseppina Della Corte, Ali El-Ali, Jackie Han, Chiara Castiglioni, Gian Luca Forni, MD

Blood (2016) 128 (22): 2466.

https://doi.org/10.1182/blood.V128.22.2466.2466

Published: 2016

Journal Articles

Safety and Efficacy of Direct-Acting Antiviral Drugs in Patients with Haemoglobinophaties and Chronic Hepatitis C Infection

Antonio Piga, MD, Paolo Rigano, MD, Raffaella Origa, MD, M. Domenica Cappellini, MD, Valeria Pinto, MD, Immacolata Tartaglione, MD, Aldo Filosa, MD, Domenico D'Ascola, MD, Vito Di Marco, Gian Luca Forni, MD

Blood (2016) 128 (22): 3627.

https://doi.org/10.1182/blood.V128.22.3627.3627

Published: 2016

Journal Articles

A randomized trial of amlodipine in addition to standard chelation therapy in patients with thalassemia major

Juliano L. Fernandes, Sandra R. Loggetto, Monica P. A. Veríssimo, Kleber Y. Fertrin, Giorgio R. Baldanzi, Luciana A. B. Fioravante, Doralice M. Tan, Tatiana Higa, Denise A. Mashima, Antonio Piga, Otavio R. Coelho, Fernando F. Costa, Sara T. Saad

Blood (2016) 128 (12): 1555–1561.

https://doi.org/10.1182/blood-2016-06-721183

Published: 2016

Includes: Supplemental data

NARROW

Efficacy and Safety of Combination Therapy with Oral Iron Chelators Deferiprone and Deferasirox in Patients with β-Thalassemia Major: A Systematic Literature Review

Erythroid Response in Patients with Non-Transfusion-Dependent β-Thalassemia Treated with Luspatercept: Long-Term Data from the BEYOND Trial

Alterations of Neuromuscular Environment Are Associated with Chronic Tissue Hypoxia in β-Thalassemia Patients

Effect of Luspatercept in β-Thalassemia Patients with β0/β0 Genotype: A Subgroup Analysis of the BELIEVE Study

Mortality in β-thalassemia patients with confirmed pulmonary arterial hypertension on right heart catheterization

Luspatercept Improves Quality of Life and Reduces Red Blood Cell Transfusion Burden in Patients with Non-Transfusion-Dependent β-Thalassemia in the BEYOND Trial

Serum GDF15 in β-Thalassemia: A Quantitative Marker of Ineffective Erythropoiesis?

COVID 19 and Hemoglobinopathies: Update of the Italian Experience

Health-Related Quality of Life Outcomes for Patients with Transfusion-Dependent Beta-Thalassemia Treated with Luspatercept in the Believe Trial

Sustained Reductions in Red Blood Cell (RBC) Transfusion Burden and Events in β-Thalassemia with Luspatercept: Longitudinal Results of the Believe Trial

Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety Comparison of Deferasirox Formulations for Treatment Tailoring

Evaluating Luspatercept Responders in the Phase 3, Randomized, Double-Blind, Placebo-Controlled BELIEVE Trial of Luspatercept in Adult Beta-Thalassemia Patients (Pts) Who Require Regular Red Blood Cell (RBC) Transfusions

Selecting ß-Thalassemia Patients for Gene Therapy: A Decision-Making Algorithm

Luspatercept improves hemoglobin levels and blood transfusion requirements in a study of patients with β-thalassemia

Hemoglobin Utilization in Asplenic and Non-Splenectomized Transfusion Dependent Thalassemia Patients Supported with Pathogen Reduced Red Blood Cell Concentrates in a Phase 3 Study (SPARC)

Liver Iron Measurements with Less Expensive Technology: Comparison of a Room-Temperature Susceptometer with SQUID in 84 Subjects

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Renal Safety after More Than a Decade of Deferasirox Use in Patients with Transfusional Hemosiderosis

Safety and Efficacy of Direct-Acting Antiviral Drugs in Patients with Haemoglobinophaties and Chronic Hepatitis C Infection

A randomized trial of amlodipine in addition to standard chelation therapy in patients with thalassemia major

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American Society of Hematology

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